SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'SOR'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)		 1d8c MALATE SYNTHASE G
(Escherichia
coli) 		3 / 3 GLN A  61
HIS A 462
PRO A 704
 None
SOR  A4000 (-3.8A)
SOR  A4000 (-3.1A)
 0.00A 1d8cA-1d8cA:
67.1		 1d8cA-1d8cA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_1
(N,N-DIMETHYLGLYCINE
OXIDASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		3 / 3 ASP A  56
THR A  89
GLU A 180
 None
SOR  A 400 (-3.3A)
MG  A 399 ( 2.5A)
 0.88A 1pj7A-4xiaA:
undetectable		 1pj7A-4xiaA:
18.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XID_A_ASCA389_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		10 / 10 TRP A  15
HIS A  53
PHE A  93
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
ASP A 292
LYS A 294
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 ( 4.9A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
None
 0.27A 1xidA-4xiaA:
57.6		 1xidA-4xiaA:
65.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XID_A_ASCA389_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 10 TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 1.29A 1xidA-4xiaA:
57.6		 1xidA-4xiaA:
65.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XIH_A_SORA389_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 HIS A  53
THR A  89
PHE A  93
VAL A 134
ASP A 256
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 ( 4.9A)
SOR  A 400 (-4.5A)
None
 1.09A 1xihA-4xiaA:
57.5		 1xihA-4xiaA:
65.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XIH_A_SORA389_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 HIS A  53
THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 1.38A 1xihA-4xiaA:
57.5		 1xihA-4xiaA:
65.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XIH_A_SORA389_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		12 / 12 TRP A  15
HIS A  53
THR A  89
PHE A  93
VAL A 134
TRP A 136
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 254
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 ( 4.9A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 4.8A)
SOR  A 400 ( 2.7A)
 0.18A 1xihA-4xiaA:
57.5		 1xihA-4xiaA:
65.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		4 / 4 LEU A  89
SER A 273
ASP A 310
ASP A 315
 None
None
SOR  A 711 ( 3.2A)
None
 1.49A 2br4B-5m6gA:
undetectable		 2br4B-5m6gA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMA_A_SAMA375_0
(PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE)		 5k4p PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1
(Escherichia
coli) 		5 / 11 GLY A 467
SER A 469
THR A 283
GLY A 479
PHE A 484
 None
None
SOR  A 611 (-3.5A)
SOR  A 611 (-3.8A)
None
 1.18A 2hmaA-5k4pA:
undetectable		 2hmaA-5k4pA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 5jo9 RIBITOL
2-DEHYDROGENASE
(Bradyrhizobium
japonicum) 		4 / 7 THR A  13
TYR A 153
ASN A 112
LEU A 190
 None
SOR  A 302 (-3.9A)
None
PO4  A 301 (-4.4A)
 1.19A 2hzqA-5jo9A:
undetectable		 2hzqA-5jo9A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5jo9 RIBITOL
2-DEHYDROGENASE
(Bradyrhizobium
japonicum) 		4 / 7 PHE A 240
PRO A 195
LEU A 199
ALA A 202
 SOR  A 302 ( 4.7A)
None
None
None
 0.90A 2vcvA-5jo9A:
undetectable		 2vcvA-5jo9A:
20.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		7 / 12 HIS A  53
THR A  89
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.23A 2xinA-4xiaA:
57.4		 2xinA-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		7 / 12 HIS A  53
THR A  89
VAL A 134
GLU A 180
GLU A 216
HIS A 219
ASP A 256
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
None
 1.32A 2xinA-4xiaA:
57.4		 2xinA-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 THR A  89
GLU A 216
HIS A 219
ASP A 256
ASP A 244
 SOR  A 400 (-3.3A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
None
MG  A 399 ( 3.1A)
 1.33A 2xinA-4xiaA:
57.4		 2xinA-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		12 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 254
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 4.8A)
SOR  A 400 ( 2.7A)
 0.47A 2xinA-4xiaA:
57.4		 2xinA-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		8 / 12 HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 256
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
None
 1.36A 2xinB-4xiaA:
57.3		 2xinB-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 THR A  89
GLU A 180
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 (-3.3A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.17A 2xinB-4xiaA:
57.3		 2xinB-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		12 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 254
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 4.8A)
SOR  A 400 ( 2.7A)
 0.45A 2xinB-4xiaA:
57.3		 2xinB-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		8 / 12 HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 256
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
None
 1.39A 2xinC-4xiaA:
57.4		 2xinC-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 THR A  89
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.22A 2xinC-4xiaA:
57.4		 2xinC-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		12 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 254
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 4.8A)
SOR  A 400 ( 2.7A)
 0.49A 2xinC-4xiaA:
57.4		 2xinC-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		7 / 12 HIS A  53
THR A  89
GLU A 180
GLU A 216
HIS A 219
ASP A 256
ASP A 244
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
None
MG  A 399 ( 3.1A)
 1.50A 2xinD-4xiaA:
57.4		 2xinD-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		7 / 12 HIS A  53
THR A  89
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 1.30A 2xinD-4xiaA:
57.4		 2xinD-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		7 / 12 HIS A  53
THR A  89
VAL A 134
GLU A 180
GLU A 216
HIS A 219
ASP A 256
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
None
 1.30A 2xinD-4xiaA:
57.4		 2xinD-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		12 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 254
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 4.8A)
SOR  A 400 ( 2.7A)
 0.45A 2xinD-4xiaA:
57.4		 2xinD-4xiaA:
67.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 HIS A  53
THR A  89
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.37A 3ximA-4xiaA:
57.5		 3ximA-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 HIS A  53
THR A  89
HIS A 219
ASP A 292
ASP A 254
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
SOR  A 400 ( 4.8A)
 1.37A 3ximA-4xiaA:
57.5		 3ximA-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 HIS A  53
THR A  89
VAL A 134
GLU A 216
ASP A 244
ASP A 256
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
MG  A 399 ( 2.8A)
MG  A 399 ( 3.1A)
None
 1.15A 3ximA-4xiaA:
57.5		 3ximA-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 1.35A 3ximA-4xiaA:
57.5		 3ximA-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		11 / 12 TRP A  15
HIS A  53
MET A  87
THR A  89
VAL A 134
TRP A 136
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.19A 3ximA-4xiaA:
57.5		 3ximA-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		9 / 12 TRP A  15
HIS A  53
MET A  87
THR A  89
VAL A 134
TRP A 136
LYS A 182
HIS A 219
ASP A 254
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
SOR  A 400 (-2.9A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 4.8A)
 0.59A 3ximA-4xiaA:
57.5		 3ximA-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		7 / 12 HIS A  53
THR A  89
VAL A 134
GLU A 180
GLU A 216
ASP A 244
ASP A 256
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
MG  A 399 ( 3.1A)
None
 1.16A 3ximB-4xiaA:
57.6		 3ximB-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 THR A  89
GLU A 180
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 (-3.3A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.20A 3ximB-4xiaA:
57.6		 3ximB-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 THR A  89
GLU A 180
HIS A 219
ASP A 292
ASP A 254
 SOR  A 400 (-3.3A)
MG  A 399 ( 2.5A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
SOR  A 400 ( 4.8A)
 1.32A 3ximB-4xiaA:
57.6		 3ximB-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 1.40A 3ximB-4xiaA:
57.6		 3ximB-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		11 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.18A 3ximB-4xiaA:
57.6		 3ximB-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		9 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
HIS A 219
ASP A 254
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 4.8A)
 0.59A 3ximB-4xiaA:
57.6		 3ximB-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 THR A  89
GLU A 180
HIS A 219
ASP A 292
ASP A 254
 SOR  A 400 (-3.3A)
MG  A 399 ( 2.5A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
SOR  A 400 ( 4.8A)
 1.37A 3ximC-4xiaA:
57.1		 3ximC-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 THR A  89
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 1.29A 3ximC-4xiaA:
57.1		 3ximC-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 THR A  89
VAL A 134
GLU A 180
GLU A 216
ASP A 244
ASP A 256
 SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
MG  A 399 ( 3.1A)
None
 1.11A 3ximC-4xiaA:
57.1		 3ximC-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		11 / 12 TRP A  15
MET A  87
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.20A 3ximC-4xiaA:
57.1		 3ximC-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		9 / 12 TRP A  15
MET A  87
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
HIS A 219
ASP A 254
 SOR  A 400 (-4.0A)
SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 4.8A)
 0.72A 3ximC-4xiaA:
57.1		 3ximC-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		7 / 12 HIS A  53
THR A  89
VAL A 134
GLU A 180
GLU A 216
ASP A 244
ASP A 256
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
MG  A 399 ( 3.1A)
None
 1.14A 3ximD-4xiaA:
57.9		 3ximD-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 THR A  89
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 1.29A 3ximD-4xiaA:
57.9		 3ximD-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 TRP A  15
HIS A  53
THR A  89
TRP A 136
LYS A 182
ASP A 254
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
SOR  A 400 (-2.9A)
SOR  A 400 ( 4.8A)
 0.75A 3ximD-4xiaA:
57.9		 3ximD-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		11 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.17A 3ximD-4xiaA:
57.9		 3ximD-4xiaA:
67.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DVO_A_SORA404_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		7 / 12 HIS A  53
THR A  89
VAL A 134
ASN A 214
GLU A 216
ASP A 244
ASP A 256
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
None
MG  A 399 ( 2.8A)
MG  A 399 ( 3.1A)
None
 1.24A 4dvoA-4xiaA:
57.5		 4dvoA-4xiaA:
65.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DVO_A_SORA404_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.32A 4dvoA-4xiaA:
57.5		 4dvoA-4xiaA:
65.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DVO_A_SORA404_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 THR A  89
TRP A 136
HIS A 219
ASP A 292
ASP A 254
 SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
SOR  A 400 ( 4.8A)
 1.33A 4dvoA-4xiaA:
57.5		 4dvoA-4xiaA:
65.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DVO_A_SORA404_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		11 / 12 TRP A  15
HIS A  53
MET A  87
THR A  89
VAL A 134
TRP A 136
LYS A 182
ASN A 214
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
SOR  A 400 (-2.9A)
None
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 0.16A 4dvoA-4xiaA:
57.5		 4dvoA-4xiaA:
65.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DVO_A_SORA404_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		10 / 12 TRP A  15
HIS A  53
MET A  87
THR A  89
VAL A 134
TRP A 136
LYS A 182
ASN A 214
HIS A 219
ASP A 254
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
SOR  A 400 (-2.9A)
None
SOR  A 400 (-4.1A)
SOR  A 400 ( 4.8A)
 0.67A 4dvoA-4xiaA:
57.5		 4dvoA-4xiaA:
65.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_A_SORA400_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 MET A  87
THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.41A 4xiaA-4xiaA:
65.0		 4xiaA-4xiaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_A_SORA400_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		12 / 12 TRP A  15
HIS A  53
MET A  87
THR A  89
VAL A 134
TRP A 136
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 254
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 4.8A)
SOR  A 400 ( 2.7A)
 0.02A 4xiaA-4xiaA:
65.0		 4xiaA-4xiaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_B_SORB400_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		7 / 12 HIS A  53
THR A  89
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.24A 4xiaB-4xiaA:
62.7		 4xiaB-4xiaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_B_SORB400_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		7 / 12 MET A  87
THR A  89
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 1.33A 4xiaB-4xiaA:
62.7		 4xiaB-4xiaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_B_SORB400_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		12 / 12 TRP A  15
HIS A  53
MET A  87
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.14A 4xiaB-4xiaA:
62.7		 4xiaB-4xiaA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_D_NMYD600_1
(BIFUNCTIONAL AAC/APH)		 1d8c MALATE SYNTHASE G
(Escherichia
coli) 		5 / 12 ASP A  58
TYR A 707
GLU A 709
GLU A 427
GLU A 398
 SOR  A4000 ( 4.4A)
None
None
MG  A3001 ( 2.6A)
None
 1.47A 5iqeD-1d8cA:
0.0		 5iqeD-1d8cA:
16.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 5jo9 RIBITOL
2-DEHYDROGENASE
(Bradyrhizobium
japonicum) 		12 / 12 TYR A  92
SER A 140
LEU A 141
THR A 147
TRP A 149
GLU A 150
GLY A 184
PRO A 185
VAL A 186
TRP A 194
PHE A 240
LEU A 242
 SOR  A 302 (-4.3A)
SOR  A 302 (-2.5A)
SOR  A 302 ( 3.8A)
SOR  A 302 (-3.8A)
SOR  A 302 ( 4.9A)
SOR  A 302 (-2.4A)
SOR  A 302 (-3.4A)
SOR  A 302 ( 2.8A)
SOR  A 302 ( 4.3A)
SOR  A 302 (-3.7A)
SOR  A 302 ( 4.7A)
SOR  A 302 ( 4.5A)
 0.12A 5jo9A-5jo9A:
45.7		 5jo9A-5jo9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 5k4p PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1
(Escherichia
coli) 		6 / 6 GLY A 282
THR A 283
SER A 284
TYR A 287
GLY A 479
ASN A 482
 SOR  A 611 (-3.1A)
SOR  A 611 (-3.5A)
SOR  A 611 (-2.8A)
SOR  A 611 ( 4.0A)
SOR  A 611 (-3.8A)
SOR  A 611 (-3.1A)
 0.00A 5k4pA-5k4pA:
61.1		 5k4pA-5k4pA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M6G_A_SORA711_0
(BETA-GLUCOSIDASE)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		5 / 12 ASP A 129
PHE A 178
MET A 275
TRP A 448
GLU A 195
 SOR  A 711 (-3.1A)
SOR  A 711 (-4.6A)
SOR  A 711 (-3.9A)
None
None
 1.43A 5m6gA-5m6gA:
70.0		 5m6gA-5m6gA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M6G_A_SORA711_0
(BETA-GLUCOSIDASE)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		7 / 12 GLY A  92
ASP A 129
ARG A 192
LYS A 231
HIS A 232
MET A 275
GLU A 505
 SOR  A 711 (-4.1A)
SOR  A 711 (-3.1A)
SOR  A 711 ( 3.0A)
SOR  A 711 (-2.5A)
GOL  A 709 ( 3.4A)
SOR  A 711 (-3.9A)
SOR  A 711 (-3.5A)
 0.93A 5m6gA-5m6gA:
70.0		 5m6gA-5m6gA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M6G_A_SORA711_0
(BETA-GLUCOSIDASE)		 5m6g BETA-GLUCOSIDASE
(Saccharopolyspor
a
erythraea) 		12 / 12 LEU A  89
GLY A  91
ASP A 129
PHE A 178
ARG A 192
LYS A 231
HIS A 232
MET A 275
TYR A 311
MET A 340
TRP A 448
GLU A 505
 None
SOR  A 711 (-3.5A)
SOR  A 711 (-3.1A)
SOR  A 711 (-4.6A)
SOR  A 711 ( 3.0A)
SOR  A 711 (-2.5A)
GOL  A 709 ( 3.4A)
SOR  A 711 (-3.9A)
SOR  A 711 ( 4.6A)
SOR  A 711 ( 3.7A)
None
SOR  A 711 (-3.5A)
 0.00A 5m6gA-5m6gA:
70.0		 5m6gA-5m6gA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_A_SORA503_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 9 HIS A  53
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.33A 5nhaA-4xiaA:
38.9		 5nhaA-4xiaA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_A_SORA503_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		8 / 9 TRP A  15
HIS A  53
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.23A 5nhaA-4xiaA:
38.9		 5nhaA-4xiaA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_B_SORB503_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		8 / 9 TRP A  15
HIS A  53
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.24A 5nhaB-4xiaA:
38.8		 5nhaB-4xiaA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_B_SORB503_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 9 TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 1.28A 5nhaB-4xiaA:
38.8		 5nhaB-4xiaA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_C_SORC503_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 9 HIS A  53
TRP A 136
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.35A 5nhaC-4xiaA:
38.8		 5nhaC-4xiaA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_C_SORC503_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		8 / 9 TRP A  15
HIS A  53
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.24A 5nhaC-4xiaA:
38.8		 5nhaC-4xiaA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_C_SORC503_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 9 TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 1.28A 5nhaC-4xiaA:
38.8		 5nhaC-4xiaA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_D_SORD503_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 9 HIS A  53
GLU A 180
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 (-4.0A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.40A 5nhaD-4xiaA:
38.9		 5nhaD-4xiaA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_D_SORD503_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		8 / 9 TRP A  15
HIS A  53
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.24A 5nhaD-4xiaA:
38.9		 5nhaD-4xiaA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_D_SORD503_0
(XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 9 TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 1.28A 5nhaD-4xiaA:
38.9		 5nhaD-4xiaA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		4 / 6 HIS A 242
HIS A 290
THR A  51
TRP A  15
 None
None
None
SOR  A 400 (-4.0A)
 1.31A 5ogjA-4xiaA:
undetectable		 5ogjA-4xiaA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5jo9 RIBITOL
2-DEHYDROGENASE
(Bradyrhizobium
japonicum) 		4 / 5 MET A 108
TYR A 153
GLY A  94
GLY A  95
 None
SOR  A 302 (-3.9A)
None
None
 1.06A 5x7pA-5jo9A:
undetectable		 5x7pA-5jo9A:
10.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 HIS A  53
THR A  89
GLU A 180
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.35A 5ximA-4xiaA:
57.6		 5ximA-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 HIS A  53
THR A  89
GLU A 180
HIS A 219
ASP A 292
ASP A 254
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
MG  A 399 ( 2.5A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
SOR  A 400 ( 4.8A)
 1.43A 5ximA-4xiaA:
57.6		 5ximA-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		7 / 12 HIS A  53
THR A  89
VAL A 134
GLU A 180
GLU A 216
ASP A 244
ASP A 256
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
MG  A 399 ( 3.1A)
None
 1.16A 5ximA-4xiaA:
57.6		 5ximA-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 244
 SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
 1.35A 5ximA-4xiaA:
57.6		 5ximA-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		11 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.18A 5ximA-4xiaA:
57.6		 5ximA-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		9 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
HIS A 219
ASP A 254
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 4.8A)
 0.65A 5ximA-4xiaA:
57.6		 5ximA-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 HIS A  53
THR A  89
VAL A 134
GLU A 216
ASP A 244
ASP A 256
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
MG  A 399 ( 2.8A)
MG  A 399 ( 3.1A)
None
 1.22A 5ximB-4xiaA:
57.5		 5ximB-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 MET A  87
THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.35A 5ximB-4xiaA:
57.5		 5ximB-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 MET A  87
THR A  89
TRP A 136
HIS A 219
ASP A 292
ASP A 254
 SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
SOR  A 400 ( 4.8A)
 1.41A 5ximB-4xiaA:
57.5		 5ximB-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		11 / 12 TRP A  15
HIS A  53
MET A  87
THR A  89
VAL A 134
TRP A 136
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.19A 5ximB-4xiaA:
57.5		 5ximB-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		10 / 12 TRP A  15
HIS A  53
MET A  87
THR A  89
VAL A 134
TRP A 136
LYS A 182
HIS A 219
ASP A 254
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
SOR  A 400 (-2.9A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 4.8A)
SOR  A 400 ( 2.7A)
 0.56A 5ximB-4xiaA:
57.5		 5ximB-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 HIS A  53
THR A  89
VAL A 134
GLU A 180
GLU A 216
ASP A 256
 SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
None
 1.21A 5ximC-4xiaA:
57.5		 5ximC-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 THR A  89
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 292
 SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
 1.27A 5ximC-4xiaA:
57.5		 5ximC-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 THR A  89
TRP A 136
GLU A 180
HIS A 219
ASP A 292
ASP A 254
 SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
SOR  A 400 ( 4.8A)
 1.35A 5ximC-4xiaA:
57.5		 5ximC-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		11 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.14A 5ximC-4xiaA:
57.5		 5ximC-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		11 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
HIS A 219
ASP A 244
ASP A 254
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 (-4.0A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 4.8A)
SOR  A 400 ( 2.7A)
 0.52A 5ximC-4xiaA:
57.5		 5ximC-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		5 / 12 THR A  89
GLU A 180
GLU A 216
ASP A 256
ASP A 244
 SOR  A 400 (-3.3A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
None
MG  A 399 ( 3.1A)
 1.39A 5ximD-4xiaA:
57.7		 5ximD-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 THR A  89
TRP A 136
GLU A 180
HIS A 219
ASP A 292
ASP A 254
 SOR  A 400 (-3.3A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 2.7A)
SOR  A 400 ( 4.8A)
 1.35A 5ximD-4xiaA:
57.7		 5ximD-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		6 / 12 THR A  89
VAL A 134
GLU A 180
GLU A 216
ASP A 244
ASP A 256
 SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
MG  A 399 ( 2.5A)
MG  A 399 ( 2.8A)
MG  A 399 ( 3.1A)
None
 1.10A 5ximD-4xiaA:
57.7		 5ximD-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		11 / 12 TRP A  15
MET A  87
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
MG  A 399 ( 2.8A)
SOR  A 400 (-4.1A)
MG  A 399 ( 3.1A)
SOR  A 400 ( 2.7A)
 0.20A 5ximD-4xiaA:
57.7		 5ximD-4xiaA:
67.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		10 / 12 TRP A  15
MET A  87
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
HIS A 219
ASP A 254
ASP A 292
 SOR  A 400 (-4.0A)
SOR  A 400 ( 4.4A)
SOR  A 400 (-3.3A)
SOR  A 400 (-4.5A)
SOR  A 400 (-3.8A)
MG  A 399 ( 2.5A)
SOR  A 400 (-2.9A)
SOR  A 400 (-4.1A)
SOR  A 400 ( 4.8A)
SOR  A 400 ( 2.7A)
 0.61A 5ximD-4xiaA:
57.7		 5ximD-4xiaA:
67.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		3 / 3 HIS A  53
ASN A  91
LEU A  92
 SOR  A 400 (-4.0A)
None
None
 0.89A 6f7lB-4xiaA:
undetectable		 6f7lB-4xiaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4xia D-XYLOSE ISOMERASE
(Arthrobacter
sp.
NRRL
B3728) 		4 / 8 TRP A  19
ASP A  56
ASP A 292
GLU A 180
 None
None
SOR  A 400 ( 2.7A)
MG  A 399 ( 2.5A)
 1.07A 6mn4C-4xiaA:
undetectable		 6mn4C-4xiaA:
23.25