SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'SO8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5fol	LEUCYL-TRNA SYNTHETASE (Cryptosporidium muris)	5 / 12	SER A 529 THR A 287 THR A 259 ALA A 536 TYR A 294	None SO8 A1544 (-3.7A) None None None	1.41A	5dsgA-5folA: undetectable	5dsgA-5folA: 20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5fol	LEUCYL-TRNA SYNTHETASE (Cryptosporidium muris)	5 / 12	SER A 529 THR A 287 THR A 259 ALA A 536 TYR A 294	None SO8 A1544 (-3.7A) None None None	1.42A	5dsgB-5folA: undetectable	5dsgB-5folA: 20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B50_A_OAQA302_0 (SULFOTRANSFERASE OXAMNIQUINE RESISTANCE PROTEIN)	5fol	LEUCYL-TRNA SYNTHETASE (Cryptosporidium muris)	5 / 12	PRO A 303 LEU A 302 ASP A 433 SER A 413 THR A 297	None None SO8 A1544 (-2.7A) None None	1.35A	6b50A-5folA: undetectable	6b50A-5folA: 21.92

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["5DSG_A_0HKA1201_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYSIN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4","5fol","LEUCYL-TRNA SYNTHETASE","Cryptosporidium muris",5,"SER A 529;THR A 287;THR A 259;ALA A 536;TYR A 294","None;SO8 A1544 (-3.7A);None;None;None","1.41A","5dsgA-5folA:undetectable",null],["5DSG_B_0HKB1201_1","MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYSIN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4","5fol","LEUCYL-TRNA SYNTHETASE","Cryptosporidium muris",5,"SER A 529;THR A 287;THR A 259;ALA A 536;TYR A 294","None;SO8 A1544 (-3.7A);None;None;None","1.42A","5dsgB-5folA:undetectable","5dsgA-5folA:20.70"],["6B50_A_OAQA302_0","SULFOTRANSFERASE OXAMNIQUINE RESISTANCE PROTEIN","5fol","LEUCYL-TRNA SYNTHETASE","Cryptosporidium muris",5,"PRO A 303;LEU A 302;ASP A 433;SER A 413;THR A 297","None;None;SO8 A1544 (-2.7A);None;None","1.35A","6b50A-5folA:undetectable","5dsgB-5folA:20.70"]]