SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'SO2'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPO_H_TESH1010_1
(ANTI-TESTOSTERONE
(HEAVY CHAIN)
ANTI-TESTOSTERONE
(LIGHT CHAIN))		 4rkm MCCA
(Wolinella
succinogenes) 		5 / 12 SER A 294
TYR A 301
ALA A 287
TYR A 285
GLY A 238
 None
HEM  A 807 ( 3.8A)
None
SO2  A 814 (-4.8A)
None
 1.27A 1vpoH-4rkmA:
undetectable
1vpoL-4rkmA:
undetectable		 1vpoH-4rkmA:
14.34
1vpoL-4rkmA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HTQ_A_ZMRA472_1
(NEURAMINIDASE)		 4rkm MCCA
(Wolinella
succinogenes) 		5 / 12 GLU A 100
ALA A 287
ARG A 218
TYR A 285
TYR A 301
 None
None
HEM  A 807 (-3.8A)
SO2  A 814 (-4.8A)
HEM  A 807 ( 3.8A)
 1.44A 2htqA-4rkmA:
undetectable		 2htqA-4rkmA:
19.24