SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'SNT'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L7I_A_VISA1202_1 (SMOOTHENED HOMOLOG,SOLUBLE CYTOCHROME B562,SMOOTHENED HOMOLOG)	4n4w	CYTOCHROME B(562),SMOOTHENED HOMOLOG (Homo sapiens; Shigella flexneri)	11 / 12	ASN A 219 TRP A 281 ASP A 384 SER A 387 TYR A 394 ARG A 400 GLN A 477 PHE A 484 GLU A 518 ASN A 521 LEU A 522	None None SNT A 605 ( 4.7A) SNT A 605 (-4.6A) None None None None SNT A 605 (-4.0A) SNT A 605 (-3.6A) SNT A 605 ( 4.4A)	0.65A	5l7iA-4n4wA: 45.6	5l7iA-4n4wA: 61.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L7I_A_VISA1202_1 (SMOOTHENED HOMOLOG,SOLUBLE CYTOCHROME B562,SMOOTHENED HOMOLOG)	4n4w	CYTOCHROME B(562),SMOOTHENED HOMOLOG (Homo sapiens; Shigella flexneri)	8 / 12	ASN A 219 TRP A 281 ASP A 384 SER A 387 TYR A 394 GLN A 477 LEU A 522 MET A 525	None None SNT A 605 ( 4.7A) SNT A 605 (-4.6A) None None SNT A 605 ( 4.4A) SNT A 605 (-4.6A)	0.73A	5l7iA-4n4wA: 45.6	5l7iA-4n4wA: 61.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L7I_B_VISB1202_1 (SMOOTHENED HOMOLOG,SOLUBLE CYTOCHROME B562,SMOOTHENED HOMOLOG)	4n4w	CYTOCHROME B(562),SMOOTHENED HOMOLOG (Homo sapiens; Shigella flexneri)	11 / 12	TRP A 281 ASP A 384 SER A 387 TYR A 394 ARG A 400 ASP A 473 GLN A 477 PRO A 513 GLU A 518 ASN A 521 LEU A 522	None SNT A 605 ( 4.7A) SNT A 605 (-4.6A) None None None None None SNT A 605 (-4.0A) SNT A 605 (-3.6A) SNT A 605 ( 4.4A)	0.60A	5l7iB-4n4wA: 37.8	5l7iB-4n4wA: 61.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5L7I_B_VISB1202_1 (SMOOTHENED HOMOLOG,SOLUBLE CYTOCHROME B562,SMOOTHENED HOMOLOG)	4n4w	CYTOCHROME B(562),SMOOTHENED HOMOLOG (Homo sapiens; Shigella flexneri)	8 / 12	TRP A 281 ASP A 384 SER A 387 TYR A 394 ASP A 473 PRO A 513 LEU A 522 MET A 525	None SNT A 605 ( 4.7A) SNT A 605 (-4.6A) None None None SNT A 605 ( 4.4A) SNT A 605 (-4.6A)	0.68A	5l7iB-4n4wA: 37.8	5l7iB-4n4wA: 61.97

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["5L7I_A_VISA1202_1","SMOOTHENED HOMOLOG,SOLUBLE CYTOCHROME B562,SMOOTHENED HOMOLOG","4n4w","CYTOCHROME B(562),SMOOTHENED HOMOLOG","Homo sapiens;Shigella flexneri",11,"ASN A 219;TRP A 281;ASP A 384;SER A 387;TYR A 394;ARG A 400;GLN A 477;PHE A 484;GLU A 518;ASN A 521;LEU A 522","None;None;SNT A 605 ( 4.7A);SNT A 605 (-4.6A);None;None;None;None;SNT A 605 (-4.0A);SNT A 605 (-3.6A);SNT A 605 ( 4.4A)","0.65A","5l7iA-4n4wA:45.6",null],["5L7I_A_VISA1202_1","SMOOTHENED HOMOLOG,SOLUBLE CYTOCHROME B562,SMOOTHENED HOMOLOG","4n4w","CYTOCHROME B(562),SMOOTHENED HOMOLOG","Homo sapiens;Shigella flexneri",8,"ASN A 219;TRP A 281;ASP A 384;SER A 387;TYR A 394;GLN A 477;LEU A 522;MET A 525","None;None;SNT A 605 ( 4.7A);SNT A 605 (-4.6A);None;None;SNT A 605 ( 4.4A);SNT A 605 (-4.6A)","0.73A","5l7iA-4n4wA:45.6","5l7iA-4n4wA:61.97"],["5L7I_B_VISB1202_1","SMOOTHENED HOMOLOG,SOLUBLE CYTOCHROME B562,SMOOTHENED HOMOLOG","4n4w","CYTOCHROME B(562),SMOOTHENED HOMOLOG","Homo sapiens;Shigella flexneri",11,"TRP A 281;ASP A 384;SER A 387;TYR A 394;ARG A 400;ASP A 473;GLN A 477;PRO A 513;GLU A 518;ASN A 521;LEU A 522","None;SNT A 605 ( 4.7A);SNT A 605 (-4.6A);None;None;None;None;None;SNT A 605 (-4.0A);SNT A 605 (-3.6A);SNT A 605 ( 4.4A)","0.60A","5l7iB-4n4wA:37.8","5l7iA-4n4wA:61.97"],["5L7I_B_VISB1202_1","SMOOTHENED HOMOLOG,SOLUBLE CYTOCHROME B562,SMOOTHENED HOMOLOG","4n4w","CYTOCHROME B(562),SMOOTHENED HOMOLOG","Homo sapiens;Shigella flexneri",8,"TRP A 281;ASP A 384;SER A 387;TYR A 394;ASP A 473;PRO A 513;LEU A 522;MET A 525","None;SNT A 605 ( 4.7A);SNT A 605 (-4.6A);None;None;None;SNT A 605 ( 4.4A);SNT A 605 (-4.6A)","0.68A","5l7iB-4n4wA:37.8","5l7iB-4n4wA:61.97"]]