SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'SLU'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5kyv LUCIFERIN
4-MONOOXYGENASE
(Photinus
pyralis) 		3 / 3 ARG A 337
ARG A 218
ASP A 224
 None
SLU  A 601 ( 4.2A)
None
 0.95A 3wipG-5kyvA:
undetectable
3wipH-5kyvA:
undetectable		 3wipG-5kyvA:
17.64
3wipH-5kyvA:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5kyv LUCIFERIN
4-MONOOXYGENASE
(Photinus
pyralis) 		4 / 8 ARG A 218
ILE A 351
VAL A 366
GLY A 341
 SLU  A 601 ( 4.2A)
None
None
SLU  A 601 (-4.0A)
 0.94A 4eq4B-5kyvA:
9.8		 4eq4B-5kyvA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDZ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5kyv LUCIFERIN
4-MONOOXYGENASE
(Photinus
pyralis) 		4 / 7 ILE A 434
GLY A 341
THR A 345
LEU A 418
 SLU  A 601 ( 4.3A)
SLU  A 601 (-4.0A)
None
None
 0.91A 4zdzA-5kyvA:
undetectable		 4zdzA-5kyvA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE3_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5kyv LUCIFERIN
4-MONOOXYGENASE
(Photinus
pyralis) 		4 / 7 ILE A 434
GLY A 341
THR A 345
LEU A 418
 SLU  A 601 ( 4.3A)
SLU  A 601 (-4.0A)
None
None
 0.85A 4ze3A-5kyvA:
undetectable		 4ze3A-5kyvA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESM_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5kyv LUCIFERIN
4-MONOOXYGENASE
(Photinus
pyralis) 		4 / 7 ILE A 434
GLY A 341
THR A 345
LEU A 418
 SLU  A 601 ( 4.3A)
SLU  A 601 (-4.0A)
None
None
 0.90A 5esmA-5kyvA:
undetectable		 5esmA-5kyvA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS1_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5kyv LUCIFERIN
4-MONOOXYGENASE
(Photinus
pyralis) 		4 / 8 ILE A 434
GLY A 341
THR A 345
LEU A 418
 SLU  A 601 ( 4.3A)
SLU  A 601 (-4.0A)
None
None
 0.86A 5hs1A-5kyvA:
undetectable		 5hs1A-5kyvA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5kyv LUCIFERIN
4-MONOOXYGENASE
(Photinus
pyralis) 		3 / 3 VAL A 366
SER A 347
MET A 398
 None
SLU  A 601 (-3.5A)
None
 0.84A 5ikqA-5kyvA:
undetectable		 5ikqA-5kyvA:
22.72