SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'SLB'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4G_A_ZMRA466_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.47A 1a4gA-4h53A:
55.1		 1a4gA-4h53A:
31.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4G_A_ZMRA466_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 371
ARG A 224
ALA A 246
GLU A 276
GLU A 277
 SLB  A 512 (-2.9A)
SLB  A 512 (-4.2A)
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
 1.29A 1a4gA-4h53A:
55.1		 1a4gA-4h53A:
31.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4G_A_ZMRA466_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 SLB  A 512 (-3.8A)
None
None
None
 0.15A 1a4gA-4h53A:
55.1		 1a4gA-4h53A:
31.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4G_B_ZMRB466_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.49A 1a4gB-4h53A:
55.1		 1a4gB-4h53A:
31.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4G_B_ZMRB466_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 371
ARG A 224
ALA A 246
GLU A 276
GLU A 277
 SLB  A 512 (-2.9A)
SLB  A 512 (-4.2A)
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
 1.28A 1a4gB-4h53A:
55.1		 1a4gB-4h53A:
31.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4G_B_ZMRB466_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ASP A 151
ARG A 152
ILE A 222
 SLB  A 512 (-3.5A)
SLB  A 512 (-3.8A)
None
 0.19A 1a4gB-4h53A:
55.1		 1a4gB-4h53A:
31.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_0
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER
(Proteus
mirabilis) 		5 / 12 PHE A 222
LEU A 239
TYR A  83
GLY A  81
ILE A  79
 None
None
None
SLB  A 503 (-3.7A)
None
 1.14A 1kglA-5nvaA:
undetectable		 1kglA-5nvaA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7F_A_BCZA801_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 156
ARG A 371
 SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.5A)
None
SLB  A 512 (-2.9A)
 1.48A 1l7fA-4h53A:
64.9		 1l7fA-4h53A:
49.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7F_A_BCZA801_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 156
TRP A 178
ILE A 222
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
 SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.5A)
None
None
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
 0.48A 1l7fA-4h53A:
64.9		 1l7fA-4h53A:
49.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 118
ARG A 152
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.8A)
SLB  A 512 (-2.9A)
 0.15A 1l7fA-4h53A:
64.9		 1l7fA-4h53A:
49.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7G_A_BCZA801_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 LEU A 134
ASP A 151
ARG A 152
ARG A 156
TRP A 178
ILE A 222
ARG A 224
GLU A 227
GLU A 276
GLU A 277
 None
SLB  A 512 (-3.5A)
SLB  A 512 (-3.8A)
None
None
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
 0.48A 1l7gA-4h53A:
64.9		 1l7gA-4h53A:
48.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7G_A_BCZA801_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 LEU A 134
ASP A 151
ARG A 152
ARG A 156
TRP A 178
ILE A 222
ARG A 224
GLU A 227
GLU A 277
ARG A 292
 None
SLB  A 512 (-3.5A)
SLB  A 512 (-3.8A)
None
None
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
 0.22A 1l7gA-4h53A:
64.9		 1l7gA-4h53A:
48.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7H_A_BCZA801_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 156
TRP A 178
ILE A 222
ARG A 224
GLU A 227
GLU A 276
GLU A 277
 SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.5A)
None
None
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
 0.49A 1l7hA-4h53A:
64.9		 1l7hA-4h53A:
48.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 118
ARG A 152
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.8A)
SLB  A 512 (-2.9A)
 0.15A 1l7hA-4h53A:
64.9		 1l7hA-4h53A:
48.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NNC_A_ZMRA479_1
(NEURAMINIDASE N9)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ARG A 152
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.8A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.29A 1nncA-4h53A:
64.6		 1nncA-4h53A:
49.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NNC_A_ZMRA479_1
(NEURAMINIDASE N9)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 224
ALA A 246
GLU A 276
GLU A 277
ARG A 118
 SLB  A 512 (-4.2A)
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-2.7A)
 1.24A 1nncA-4h53A:
64.6		 1nncA-4h53A:
49.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NNC_A_ZMRA479_2
(NEURAMINIDASE N9)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ASP A 151
ARG A 156
TRP A 178
ILE A 222
 SLB  A 512 (-3.5A)
None
None
None
 0.16A 1nncA-4h53A:
64.6		 1nncA-4h53A:
49.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OLT_A_SAMA501_0
(OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE)		 4mnp N-ACETYLNEURAMINATE-
BINDING PROTEIN
(Fusobacterium
nucleatum) 		5 / 12 THR A  11
GLU A  18
ASP A  51
ILE A 211
TYR A 158
 SLB  A 401 (-4.0A)
None
SLB  A 401 (-3.3A)
None
None
 1.38A 1oltA-4mnpA:
undetectable		 1oltA-4mnpA:
21.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_A_ZMRA1477_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.25A 2cmlA-4h53A:
64.8		 2cmlA-4h53A:
51.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_A_ZMRA1477_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 371
ARG A 224
ALA A 246
GLU A 276
GLU A 277
 SLB  A 512 (-2.9A)
SLB  A 512 (-4.2A)
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
 1.32A 2cmlA-4h53A:
64.8		 2cmlA-4h53A:
51.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_A_ZMRA1477_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ARG A 152
ARG A 156
TRP A 178
ILE A 222
 None
SLB  A 512 (-3.8A)
None
None
None
 0.19A 2cmlA-4h53A:
64.8		 2cmlA-4h53A:
51.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_B_ZMRB2477_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.21A 2cmlB-4h53A:
64.7		 2cmlB-4h53A:
51.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_B_ZMRB2477_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ARG A 152
ARG A 156
TRP A 178
ILE A 222
 None
SLB  A 512 (-3.8A)
None
None
None
 0.23A 2cmlB-4h53A:
64.7		 2cmlB-4h53A:
51.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_C_ZMRC3477_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.24A 2cmlC-4h53A:
64.7		 2cmlC-4h53A:
51.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_C_ZMRC3477_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ARG A 152
ARG A 156
TRP A 178
ILE A 222
 None
SLB  A 512 (-3.8A)
None
None
None
 0.29A 2cmlC-4h53A:
64.7		 2cmlC-4h53A:
51.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_D_ZMRD4477_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.25A 2cmlD-4h53A:
64.7		 2cmlD-4h53A:
51.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_D_ZMRD4477_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ARG A 152
ARG A 156
TRP A 178
ILE A 222
 None
SLB  A 512 (-3.8A)
None
None
None
 0.24A 2cmlD-4h53A:
64.7		 2cmlD-4h53A:
51.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HTQ_A_ZMRA472_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ARG A 152
ARG A 156
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.8A)
None
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 (-2.9A)
 0.50A 2htqA-4h53A:
63.1		 2htqA-4h53A:
47.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HTQ_A_ZMRA472_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ASP A 151
TRP A 178
ILE A 222
ARG A 224
 SLB  A 512 (-3.5A)
None
None
SLB  A 512 (-4.2A)
 0.37A 2htqA-4h53A:
63.1		 2htqA-4h53A:
47.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HTU_A_BCZA801_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 GLU A 119
LEU A 134
ARG A 152
ARG A 156
TRP A 178
SER A 179
ILE A 222
ARG A 224
GLU A 276
ARG A 292
 SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.8A)
None
None
SLB  A 512 ( 4.4A)
None
SLB  A 512 (-4.2A)
SLB  A 512 (-2.8A)
SLB  A 512 (-3.1A)
 0.52A 2htuA-4h53A:
64.0		 2htuA-4h53A:
47.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HTU_A_BCZA801_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 118
ASP A 151
GLU A 227
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
None
SLB  A 512 (-2.9A)
 0.40A 2htuA-4h53A:
64.0		 2htuA-4h53A:
47.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3B7E_A_ZMRA1001_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.25A 3b7eA-4h53A:
64.2		 3b7eA-4h53A:
47.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3B7E_A_ZMRA1001_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 SLB  A 512 (-3.8A)
None
None
None
 0.09A 3b7eA-4h53A:
64.2		 3b7eA-4h53A:
47.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3B7E_B_ZMRB1002_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.23A 3b7eB-4h53A:
64.2		 3b7eB-4h53A:
47.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3B7E_B_ZMRB1002_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 SLB  A 512 (-3.8A)
None
None
None
 0.11A 3b7eB-4h53A:
64.2		 3b7eB-4h53A:
47.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CKZ_A_ZMRA469_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		9 / 12 ARG A 118
GLU A 119
ARG A 152
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.8A)
None
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.42A 3ckzA-4h53A:
64.0		 3ckzA-4h53A:
47.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CKZ_A_ZMRA469_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 227
ARG A 152
GLU A 276
ARG A 292
ASN A 294
 None
SLB  A 512 (-3.8A)
SLB  A 512 (-2.8A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
 1.17A 3ckzA-4h53A:
64.0		 3ckzA-4h53A:
47.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CKZ_A_ZMRA469_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 6 ASP A 151
ARG A 156
TRP A 178
ILE A 222
ARG A 224
 SLB  A 512 (-3.5A)
None
None
None
SLB  A 512 (-4.2A)
 0.68A 3ckzA-4h53A:
64.0		 3ckzA-4h53A:
47.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K37_A_BCZA468_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 156
TRP A 178
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
None
None
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
 0.47A 3k37A-4h53A:
55.1		 3k37A-4h53A:
32.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K37_A_BCZA468_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ASP A 151
ARG A 152
ARG A 371
 SLB  A 512 (-3.5A)
SLB  A 512 (-3.8A)
SLB  A 512 (-2.9A)
 0.29A 3k37A-4h53A:
55.1		 3k37A-4h53A:
32.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K37_B_BCZB468_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 156
TRP A 178
ARG A 224
GLU A 227
ALA A 246
GLU A 277
ARG A 292
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.5A)
None
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 (-2.9A)
 0.39A 3k37B-4h53A:
55.0		 3k37B-4h53A:
32.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_A_BCZA1001_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.8A)
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
 0.62A 3k39A-4h53A:
54.5		 3k39A-4h53A:
31.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_B_BCZB1001_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 277
ARG A 292
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.5A)
SLB  A 512 (-3.8A)
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
 0.55A 3k39B-4h53A:
54.6		 3k39B-4h53A:
31.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_B_BCZB1001_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 156
ARG A 371
 SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.5A)
None
SLB  A 512 (-2.9A)
 1.46A 3k39B-4h53A:
54.6		 3k39B-4h53A:
31.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_C_BCZC1001_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.5A)
SLB  A 512 (-3.8A)
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
 0.61A 3k39C-4h53A:
54.3		 3k39C-4h53A:
31.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_C_BCZC1001_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 156
ARG A 371
 SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.5A)
None
SLB  A 512 (-2.9A)
 1.47A 3k39C-4h53A:
54.3		 3k39C-4h53A:
31.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_D_BCZD1001_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ARG A 371
 SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.5A)
SLB  A 512 (-3.8A)
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 (-2.9A)
 0.62A 3k39D-4h53A:
54.6		 3k39D-4h53A:
31.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_E_BCZE1001_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.8A)
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
 0.61A 3k39E-4h53A:
54.6		 3k39E-4h53A:
31.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_F_BCZF1001_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.8A)
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
 0.60A 3k39F-4h53A:
54.5		 3k39F-4h53A:
31.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_G_BCZG1001_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.8A)
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
 0.60A 3k39G-4h53A:
54.6		 3k39G-4h53A:
31.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_H_BCZH1001_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.8A)
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
 0.61A 3k39H-4h53A:
54.5		 3k39H-4h53A:
31.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_I_BCZI1001_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.5A)
SLB  A 512 (-3.8A)
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
 0.61A 3k39I-4h53A:
54.5		 3k39I-4h53A:
31.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_I_BCZI1001_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 156
ARG A 371
 SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.5A)
None
SLB  A 512 (-2.9A)
 1.46A 3k39I-4h53A:
54.5		 3k39I-4h53A:
31.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_J_BCZJ1001_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.5A)
SLB  A 512 (-3.8A)
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
 0.61A 3k39J-4h53A:
54.3		 3k39J-4h53A:
31.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_J_BCZJ1001_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 156
ARG A 371
 SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.5A)
None
SLB  A 512 (-2.9A)
 1.47A 3k39J-4h53A:
54.3		 3k39J-4h53A:
31.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_K_BCZK1001_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.5A)
SLB  A 512 (-3.8A)
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
 0.61A 3k39K-4h53A:
54.3		 3k39K-4h53A:
31.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_K_BCZK1001_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 156
ARG A 371
 SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.5A)
None
SLB  A 512 (-2.9A)
 1.47A 3k39K-4h53A:
54.3		 3k39K-4h53A:
31.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_L_BCZL1001_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.5A)
SLB  A 512 (-3.8A)
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
 0.60A 3k39L-4h53A:
54.3		 3k39L-4h53A:
31.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_L_BCZL1001_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 156
ARG A 371
 SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.5A)
None
SLB  A 512 (-2.9A)
 1.48A 3k39L-4h53A:
54.3		 3k39L-4h53A:
31.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_M_BCZM1001_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.8A)
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
 0.61A 3k39M-4h53A:
54.5		 3k39M-4h53A:
31.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_N_BCZN1001_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ARG A 371
 SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.8A)
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 (-2.9A)
 0.60A 3k39N-4h53A:
54.4		 3k39N-4h53A:
31.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_O_BCZO1001_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.8A)
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-2.9A)
 0.63A 3k39O-4h53A:
54.6		 3k39O-4h53A:
31.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_P_BCZP1001_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ARG A 371
 SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.8A)
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 (-2.9A)
 0.61A 3k39P-4h53A:
54.5		 3k39P-4h53A:
31.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SAN_A_ZMRA901_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.20A 3sanA-4h53A:
65.3		 3sanA-4h53A:
45.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SAN_A_ZMRA901_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 ASP A 151
ARG A 152
ARG A 156
TRP A 178
ILE A 222
 SLB  A 512 (-3.5A)
SLB  A 512 (-3.8A)
None
None
None
 0.12A 3sanA-4h53A:
65.3		 3sanA-4h53A:
45.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SAN_B_ZMRB901_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.19A 3sanB-4h53A:
65.2		 3sanB-4h53A:
45.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SAN_B_ZMRB901_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 ASP A 151
ARG A 152
ARG A 156
TRP A 178
ILE A 222
 SLB  A 512 (-3.5A)
SLB  A 512 (-3.8A)
None
None
None
 0.12A 3sanB-4h53A:
65.2		 3sanB-4h53A:
45.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TI5_A_ZMRA1002_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.23A 3ti5A-4h53A:
64.5		 3ti5A-4h53A:
47.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TI5_A_ZMRA1002_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 SLB  A 512 (-3.8A)
None
None
None
 0.13A 3ti5A-4h53A:
64.5		 3ti5A-4h53A:
47.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TI5_B_ZMRB1002_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.24A 3ti5B-4h53A:
64.5		 3ti5B-4h53A:
47.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TI5_B_ZMRB1002_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 SLB  A 512 (-3.8A)
None
None
None
 0.12A 3ti5B-4h53A:
64.5		 3ti5B-4h53A:
47.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_A_ZMRA1002_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
TRP A 178
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
None
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.15A 3ticA-4h53A:
76.4		 3ticA-4h53A:
99.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_A_ZMRA1002_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ARG A 152
ARG A 156
ILE A 222
ARG A 224
 None
SLB  A 512 (-3.8A)
None
None
SLB  A 512 (-4.2A)
 0.08A 3ticA-4h53A:
76.4		 3ticA-4h53A:
99.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_B_ZMRB1002_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.14A 3ticB-4h53A:
76.4		 3ticB-4h53A:
99.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_B_ZMRB1002_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 SLB  A 512 (-3.8A)
None
None
None
 0.08A 3ticB-4h53A:
76.4		 3ticB-4h53A:
99.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_C_ZMRC1002_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.15A 3ticC-4h53A:
76.4		 3ticC-4h53A:
99.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_C_ZMRC1002_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 SLB  A 512 (-3.8A)
None
None
None
 0.08A 3ticC-4h53A:
76.4		 3ticC-4h53A:
99.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_D_ZMRD1002_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.15A 3ticD-4h53A:
76.4		 3ticD-4h53A:
99.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_D_ZMRD1002_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ARG A 152
ARG A 156
TRP A 178
ILE A 222
 None
SLB  A 512 (-3.8A)
None
None
None
 0.07A 3ticD-4h53A:
76.4		 3ticD-4h53A:
99.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UM5_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 10 ILE A 257
PHE A 205
THR A 225
SER A 179
ILE A 194
 None
None
None
SLB  A 512 ( 4.4A)
None
 1.08A 3um5A-4h53A:
undetectable		 3um5A-4h53A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UM5_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 10 ILE A 257
PHE A 205
THR A 225
SER A 179
ILE A 194
 None
None
None
SLB  A 512 ( 4.4A)
None
 1.07A 3um5B-4h53A:
undetectable		 3um5B-4h53A:
19.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7N_A_ZMRA601_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.30A 4b7nA-4h53A:
64.0		 4b7nA-4h53A:
41.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7N_A_ZMRA601_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
TRP A 178
 SLB  A 512 (-3.8A)
None
None
 0.08A 4b7nA-4h53A:
64.0		 4b7nA-4h53A:
41.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_A_ZMRA601_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.32A 4b7qA-4h53A:
63.9		 4b7qA-4h53A:
41.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
ILE A 222
 SLB  A 512 (-3.8A)
None
None
 0.22A 4b7qA-4h53A:
63.9		 4b7qA-4h53A:
41.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_B_ZMRB601_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.30A 4b7qB-4h53A:
63.9		 4b7qB-4h53A:
41.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_B_ZMRB601_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 LEU A 134
ARG A 152
ARG A 156
TRP A 178
 None
SLB  A 512 (-3.8A)
None
None
 0.14A 4b7qB-4h53A:
63.9		 4b7qB-4h53A:
41.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_C_ZMRC601_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.33A 4b7qC-4h53A:
63.7		 4b7qC-4h53A:
41.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
ILE A 222
 SLB  A 512 (-3.8A)
None
None
 0.18A 4b7qC-4h53A:
63.7		 4b7qC-4h53A:
41.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_D_ZMRD601_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.33A 4b7qD-4h53A:
63.9		 4b7qD-4h53A:
41.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_D_ZMRD601_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 SLB  A 512 (-3.8A)
None
None
None
 0.25A 4b7qD-4h53A:
63.9		 4b7qD-4h53A:
41.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_A_ZMRA700_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.53A 4cpnA-4h53A:
55.2		 4cpnA-4h53A:
28.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_A_ZMRA700_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 371
ARG A 224
ALA A 246
GLU A 276
GLU A 277
 SLB  A 512 (-2.9A)
SLB  A 512 (-4.2A)
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
 1.25A 4cpnA-4h53A:
55.2		 4cpnA-4h53A:
28.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_A_ZMRA700_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 SLB  A 512 (-3.8A)
None
None
None
 0.10A 4cpnA-4h53A:
55.2		 4cpnA-4h53A:
28.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_B_ZMRB700_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 (-2.9A)
 0.48A 4cpnB-4h53A:
55.1		 4cpnB-4h53A:
28.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_B_ZMRB700_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 371
ARG A 224
ALA A 246
GLU A 276
GLU A 277
 SLB  A 512 (-2.9A)
SLB  A 512 (-4.2A)
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
 1.30A 4cpnB-4h53A:
55.1		 4cpnB-4h53A:
28.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_A_ZMRA1471_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.52A 4cpzA-4h53A:
55.0		 4cpzA-4h53A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_A_ZMRA1471_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 371
ARG A 224
ALA A 246
GLU A 276
GLU A 277
 SLB  A 512 (-2.9A)
SLB  A 512 (-4.2A)
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
 1.21A 4cpzA-4h53A:
55.0		 4cpzA-4h53A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_A_ZMRA1471_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ASP A 151
ARG A 152
ARG A 156
TRP A 178
 None
SLB  A 512 (-3.5A)
SLB  A 512 (-3.8A)
None
None
 0.19A 4cpzA-4h53A:
55.0		 4cpzA-4h53A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_B_ZMRB1471_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.47A 4cpzB-4h53A:
14.8		 4cpzB-4h53A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_B_ZMRB1471_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 371
ARG A 224
ALA A 246
GLU A 276
GLU A 277
 SLB  A 512 (-2.9A)
SLB  A 512 (-4.2A)
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
 1.24A 4cpzB-4h53A:
14.8		 4cpzB-4h53A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_B_ZMRB1471_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ASP A 151
ARG A 152
ARG A 156
TRP A 178
 SLB  A 512 (-3.5A)
SLB  A 512 (-3.8A)
None
None
 0.20A 4cpzB-4h53A:
14.8		 4cpzB-4h53A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.50A 4cpzC-4h53A:
54.9		 4cpzC-4h53A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 371
ARG A 224
ALA A 246
GLU A 276
GLU A 277
 SLB  A 512 (-2.9A)
SLB  A 512 (-4.2A)
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
 1.22A 4cpzC-4h53A:
54.9		 4cpzC-4h53A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
TRP A 178
 SLB  A 512 (-3.8A)
None
None
 0.18A 4cpzC-4h53A:
54.9		 4cpzC-4h53A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_D_ZMRD1471_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.46A 4cpzD-4h53A:
54.6		 4cpzD-4h53A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_D_ZMRD1471_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 371
ARG A 224
ALA A 246
GLU A 276
GLU A 277
 SLB  A 512 (-2.9A)
SLB  A 512 (-4.2A)
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
 1.27A 4cpzD-4h53A:
54.6		 4cpzD-4h53A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_D_ZMRD1471_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ASP A 151
ARG A 152
ARG A 156
TRP A 178
 SLB  A 512 (-3.5A)
SLB  A 512 (-3.8A)
None
None
 0.17A 4cpzD-4h53A:
54.8		 4cpzD-4h53A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 (-2.9A)
 0.53A 4cpzE-4h53A:
54.6		 4cpzE-4h53A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 371
ARG A 224
ALA A 246
GLU A 276
GLU A 277
 SLB  A 512 (-2.9A)
SLB  A 512 (-4.2A)
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
 1.21A 4cpzE-4h53A:
54.6		 4cpzE-4h53A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
TRP A 178
 SLB  A 512 (-3.8A)
None
None
 0.18A 4cpzE-4h53A:
54.6		 4cpzE-4h53A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.53A 4cpzF-4h53A:
54.7		 4cpzF-4h53A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 371
ARG A 224
ALA A 246
GLU A 276
GLU A 277
 SLB  A 512 (-2.9A)
SLB  A 512 (-4.2A)
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
 1.23A 4cpzF-4h53A:
54.7		 4cpzF-4h53A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
TRP A 178
 SLB  A 512 (-3.8A)
None
None
 0.13A 4cpzF-4h53A:
54.7		 4cpzF-4h53A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.51A 4cpzG-4h53A:
54.6		 4cpzG-4h53A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 371
ARG A 224
ALA A 246
GLU A 276
GLU A 277
 SLB  A 512 (-2.9A)
SLB  A 512 (-4.2A)
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
 1.31A 4cpzG-4h53A:
54.6		 4cpzG-4h53A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
TRP A 178
 SLB  A 512 (-3.8A)
None
None
 0.15A 4cpzG-4h53A:
54.6		 4cpzG-4h53A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.56A 4cpzH-4h53A:
54.7		 4cpzH-4h53A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 371
ARG A 224
ALA A 246
GLU A 276
GLU A 277
 SLB  A 512 (-2.9A)
SLB  A 512 (-4.2A)
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
 1.27A 4cpzH-4h53A:
54.7		 4cpzH-4h53A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
TRP A 178
 SLB  A 512 (-3.8A)
None
None
 0.20A 4cpzH-4h53A:
54.7		 4cpzH-4h53A:
28.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4I00_A_ZMRA509_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 152
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.8A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 (-2.9A)
 0.45A 4i00A-4h53A:
65.5		 4i00A-4h53A:
53.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4I00_A_ZMRA509_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 227
ARG A 152
ALA A 246
GLU A 276
ARG A 292
 None
SLB  A 512 (-3.8A)
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-3.1A)
 1.49A 4i00A-4h53A:
65.5		 4i00A-4h53A:
53.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4I00_A_ZMRA509_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ARG A 156
TRP A 178
ILE A 222
ASN A 294
 None
None
None
None
SLB  A 512 ( 4.2A)
 0.86A 4i00A-4h53A:
65.5		 4i00A-4h53A:
53.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWR_A_ZMRA513_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.16A 4mwrA-4h53A:
64.8		 4mwrA-4h53A:
49.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWR_A_ZMRA513_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 224
ALA A 246
GLU A 276
GLU A 277
ARG A 118
 SLB  A 512 (-4.2A)
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-2.7A)
 1.31A 4mwrA-4h53A:
64.8		 4mwrA-4h53A:
49.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWR_A_ZMRA513_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ASP A 151
ARG A 152
TRP A 178
ILE A 222
 None
SLB  A 512 (-3.5A)
SLB  A 512 (-3.8A)
None
None
 0.15A 4mwrA-4h53A:
64.8		 4mwrA-4h53A:
49.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWV_A_BCZA513_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ASP A 151
ARG A 152
ILE A 222
ARG A 224
GLU A 227
 SLB  A 512 (-3.5A)
SLB  A 512 (-3.8A)
None
SLB  A 512 (-4.2A)
None
 1.35A 4mwvA-4h53A:
64.8		 4mwvA-4h53A:
49.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWV_A_BCZA513_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
TRP A 178
ILE A 222
ARG A 224
GLU A 276
GLU A 277
ARG A 292
 SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.5A)
SLB  A 512 (-3.8A)
None
None
None
SLB  A 512 (-4.2A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
 0.45A 4mwvA-4h53A:
64.8		 4mwvA-4h53A:
49.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWV_A_BCZA513_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 156
ARG A 371
 SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.5A)
None
SLB  A 512 (-2.9A)
 1.48A 4mwvA-4h53A:
64.8		 4mwvA-4h53A:
49.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWV_A_BCZA513_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 118
GLU A 227
ARG A 371
 SLB  A 512 (-2.7A)
None
SLB  A 512 (-2.9A)
 0.13A 4mwvA-4h53A:
64.8		 4mwvA-4h53A:
49.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWX_A_ZMRA513_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-2.9A)
 0.25A 4mwxA-4h53A:
64.7		 4mwxA-4h53A:
49.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWX_A_ZMRA513_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 224
ALA A 246
GLU A 276
GLU A 277
ARG A 118
 SLB  A 512 (-4.2A)
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-2.7A)
 1.25A 4mwxA-4h53A:
64.7		 4mwxA-4h53A:
49.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWX_A_ZMRA513_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
TRP A 178
ILE A 222
 SLB  A 512 (-3.8A)
None
None
 0.08A 4mwxA-4h53A:
64.7		 4mwxA-4h53A:
49.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MX0_A_BCZA513_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 GLU A 119
LEU A 134
ARG A 152
ARG A 156
TRP A 178
SER A 179
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
 SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.8A)
None
None
SLB  A 512 ( 4.4A)
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
 0.45A 4mx0A-4h53A:
64.6		 4mx0A-4h53A:
49.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MX0_A_BCZA513_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 118
ASP A 151
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-2.9A)
 0.28A 4mx0A-4h53A:
64.6		 4mx0A-4h53A:
49.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER
(Proteus
mirabilis) 		5 / 11 LEU A 239
PHE A 243
GLN A  82
THR A  63
ILE A  62
 None
SLB  A 503 (-3.6A)
SLB  A 503 (-3.1A)
SLB  A 503 (-3.0A)
SLB  A 503 (-3.5A)
 1.40A 4uuuA-5nvaA:
undetectable
4uuuB-5nvaA:
undetectable		 4uuuA-5nvaA:
undetectable
4uuuB-5nvaA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA5_A_ZMRA501_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ASP A 151
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 ( 4.2A)
SLB  A 512 (-2.9A)
 0.58A 4wa5A-4h53A:
63.3		 4wa5A-4h53A:
48.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA5_A_ZMRA501_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 ARG A 152
ARG A 156
TRP A 178
ILE A 222
ARG A 224
 SLB  A 512 (-3.8A)
None
None
None
SLB  A 512 (-4.2A)
 0.53A 4wa5A-4h53A:
63.3		 4wa5A-4h53A:
48.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQC_A_51GA600_1
(BIFUNCTIONAL AAC/APH)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 10 SER A 179
ASP A 198
GLU A 119
GLU A 277
GLU A 227
 SLB  A 512 ( 4.4A)
None
SLB  A 512 (-3.5A)
SLB  A 512 (-2.7A)
None
 1.49A 5iqcA-4h53A:
0.2		 5iqcA-4h53A:
22.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L17_A_ZMRA512_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-2.7A)
SLB  A 512 (-3.1A)
SLB  A 512 (-2.9A)
 0.24A 5l17A-4h53A:
64.9		 5l17A-4h53A:
48.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L17_A_ZMRA512_2
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 LEU A 134
ARG A 152
TRP A 178
ILE A 222
 None
SLB  A 512 (-3.8A)
None
None
 0.15A 5l17A-4h53A:
64.9		 5l17A-4h53A:
48.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MQT_A_STIA302_1
(DEOXYCYTIDINE KINASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 VAL A 398
GLU A 277
PHE A 422
SER A 279
GLU A 375
 None
SLB  A 512 (-2.7A)
None
None
None
 1.47A 5mqtA-4h53A:
undetectable		 5mqtA-4h53A:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND3_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ASP A 406
GLU A 227
LEU A 159
SER A 180
THR A 138
 SLB  A 512 ( 4.1A)
None
None
None
None
 1.23A 5nd3B-4h53A:
undetectable		 5nd3B-4h53A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)		 4hiz ENDOSIALIDASE
(Enterobacteria
phage
phi92) 		5 / 12 VAL A 305
VAL A 289
GLY A 263
THR A 297
GLY A 298
 None
None
None
SLB  A 801 ( 4.5A)
SLB  A 801 (-3.5A)
 1.05A 6brdC-4hizA:
undetectable		 6brdC-4hizA:
7.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)		 4hiz ENDOSIALIDASE
(Enterobacteria
phage
phi92) 		5 / 12 VAL A 305
VAL A 289
GLY A 264
THR A 297
GLY A 298
 None
None
None
SLB  A 801 ( 4.5A)
SLB  A 801 (-3.5A)
 1.17A 6brdC-4hizA:
undetectable		 6brdC-4hizA:
7.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_0
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
ARG A 292
ARG A 371
 SLB  A 512 (-2.7A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.5A)
SLB  A 512 (-3.8A)
None
SLB  A 512 (-4.2A)
None
SLB  A 512 (-3.3A)
SLB  A 512 (-2.8A)
SLB  A 512 (-3.1A)
SLB  A 512 (-2.9A)
 0.22A 6hcxA-4h53A:
18.4		 6hcxA-4h53A:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 TRP A 178
ILE A 222
GLU A 277
 None
None
SLB  A 512 (-2.7A)
 0.10A 6hcxA-4h53A:
18.4		 6hcxA-4h53A:
11.41