SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'SIO'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF3_A_PAUA314_0
(PANTOTHENATE KINASE)		 3i1l HEMAGGLUTININ-ESTERA
SE PROTEIN
(Porcine
torovirus) 		4 / 6 ARG A 161
MET A 221
PHE A 219
PHE A 228
 SIO  A1001 (-3.4A)
SIO  A1001 (-3.7A)
SIO  A1001 (-3.5A)
None
 1.48A 3af3A-3i1lA:
undetectable		 3af3A-3i1lA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 3i1l HEMAGGLUTININ-ESTERA
SE PROTEIN
(Porcine
torovirus) 		4 / 8 ASN A 177
TRP A  83
GLN A 179
THR A 164
 None
None
NAG  A5155 (-4.0A)
SIO  A1001 (-4.3A)
 1.36A 4d1yA-3i1lA:
undetectable
4d1yB-3i1lA:
undetectable		 4d1yA-3i1lA:
16.93
4d1yB-3i1lA:
16.93