SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'SIC'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_B_SAMB401_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 3dip ENOLASE
(unidentified) 		5 / 12 GLY A 331
ALA A 338
HIS A 320
LEU A 292
VAL A 290
 None
None
SIC  A 321 ( 3.1A)
None
None
 0.90A 2yqzB-3dipA:
undetectable		 2yqzB-3dipA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3dip ENOLASE
(unidentified) 		3 / 3 THR A 323
HIS A 337
LEU A 300
 SIC  A 321 ( 3.8A)
None
None
 0.85A 5axdC-3dipA:
2.6		 5axdC-3dipA:
25.89