SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'SIA'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_A_ZMRA466_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.47A 1a4gA-2bf6A:
25.0		 1a4gA-2bf6A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 12 ARG A 266
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.37A 1a4gB-2bf6A:
24.9		 1a4gB-2bf6A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)		 4mbz MAJOR CAPSID PROTEIN
VP1
(African
green
monkey
polyomavirus) 		3 / 3 GLN A 130
HIS A 271
PRO A 144
 SIA  A 406 (-4.3A)
SIA  A 406 (-4.2A)
None
 0.90A 1d8cA-4mbzA:
undetectable		 1d8cA-4mbzA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKO_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 4kps HEMAGGLUTININ
(Influenza
A
virus) 		5 / 10 ASN A 150
VAL A  67
GLY A  68
TRP A 153
LEU A 252
 None
None
None
SIA  A 801 (-3.6A)
None
 1.22A 1fkoA-4kpsA:
undetectable		 1fkoA-4kpsA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NNC_A_ZMRA479_1
(NEURAMINIDASE N9)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 12 ARG A 266
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.51A 1nncA-2bf6A:
21.1		 1nncA-2bf6A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		4 / 8 ARG A 517
ASN A 514
GLN A 493
ASN A 562
 None
None
SIA  A1692 (-3.0A)
None
 1.15A 1p6kA-2bf6A:
undetectable		 1p6kA-2bf6A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		4 / 8 ARG A 517
ASN A 514
GLN A 493
ASN A 562
 None
None
SIA  A1692 (-3.0A)
None
 1.08A 1p6kB-2bf6A:
undetectable		 1p6kB-2bf6A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 11 PHE A 341
PHE A 460
LEU A 461
VAL A 453
VAL A 484
 None
SIA  A1692 ( 4.9A)
None
None
None
 1.35A 1q23J-2bf6A:
undetectable		 1q23J-2bf6A:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_ACTA421_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 2w68 SIALIDASE
(Vibrio
cholerae) 		5 / 8 GLY A  70
GLY A 202
GLY A 106
MET A 107
SER A 197
 None
None
None
SIA  A1217 ( 4.7A)
SIA  A1217 (-3.7A)
 1.15A 1qzzA-2w68A:
undetectable		 1qzzA-2w68A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		4 / 8 ARG A 517
ASN A 514
GLN A 493
ASN A 562
 None
None
SIA  A1692 (-3.0A)
None
 1.20A 1rs6A-2bf6A:
undetectable		 1rs6A-2bf6A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		4 / 8 ARG A 517
ASN A 514
GLN A 493
ASN A 562
 None
None
SIA  A1692 (-3.0A)
None
 1.09A 1rs6B-2bf6A:
undetectable		 1rs6B-2bf6A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		4 / 8 ARG A 517
ASN A 514
GLN A 493
ASN A 562
 None
None
SIA  A1692 (-3.0A)
None
 1.05A 1rs7B-2bf6A:
undetectable		 1rs7B-2bf6A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3E_B_ZMRB2200_1
(HEMAGGLUTININ-NEURAM
INIDASE GLYCOPROTEIN)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 10 ARG A 266
TYR A 485
GLU A 539
ARG A 555
ARG A 615
 SIA  A1692 (-2.7A)
SIA  A1692 (-4.7A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
 0.72A 1v3eB-2bf6A:
9.2		 1v3eB-2bf6A:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3E_B_ZMRB2200_1
(HEMAGGLUTININ-NEURAM
INIDASE GLYCOPROTEIN)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 10 ARG A 266
TYR A 485
GLU A 539
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-4.7A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.85A 1v3eB-2bf6A:
9.2		 1v3eB-2bf6A:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 2wbv FIBER PROTEIN
(Canine
mastadenovirus
A) 		5 / 11 PHE A 516
VAL A 411
PHE A 519
GLY A 404
ILE A 377
 None
None
None
None
SIA  A1545 ( 4.3A)
 1.04A 1z11B-2wbvA:
undetectable		 1z11B-2wbvA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		4 / 8 ARG A 517
ASN A 514
GLN A 493
ASN A 562
 None
None
SIA  A1692 (-3.0A)
None
 1.17A 1zzqA-2bf6A:
undetectable		 1zzqA-2bf6A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		4 / 8 ARG A 517
ASN A 514
GLN A 493
ASN A 562
 None
None
SIA  A1692 (-3.0A)
None
 1.10A 1zzqB-2bf6A:
undetectable		 1zzqB-2bf6A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		4 / 8 ARG A 517
ASN A 514
GLN A 493
ASN A 562
 None
None
SIA  A1692 (-3.0A)
None
 1.09A 1zzuB-2bf6A:
undetectable		 1zzuB-2bf6A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1477_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.50A 2cmlA-2bf6A:
21.3		 2cmlA-2bf6A:
22.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 7 SER A 367
SER A 370
SER A 372
ASN A 400
TRP A 403
 SIA  A 510 (-2.5A)
SIA  A 510 (-2.6A)
SIA  A 510 (-2.8A)
SIA  A 510 (-3.4A)
SIA  A 510 (-3.5A)
 0.72A 2cmlA-4h53A:
64.8		 2cmlA-4h53A:
51.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2477_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.50A 2cmlB-2bf6A:
3.0		 2cmlB-2bf6A:
22.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 8 SER A 367
SER A 370
SER A 372
ASN A 400
TRP A 403
 SIA  A 510 (-2.5A)
SIA  A 510 (-2.6A)
SIA  A 510 (-2.8A)
SIA  A 510 (-3.4A)
SIA  A 510 (-3.5A)
 0.48A 2cmlB-4h53A:
64.7		 2cmlB-4h53A:
51.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3477_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.53A 2cmlC-2bf6A:
21.5		 2cmlC-2bf6A:
22.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 8 SER A 367
SER A 370
SER A 372
ASN A 400
TRP A 403
 SIA  A 510 (-2.5A)
SIA  A 510 (-2.6A)
SIA  A 510 (-2.8A)
SIA  A 510 (-3.4A)
SIA  A 510 (-3.5A)
 0.76A 2cmlC-4h53A:
64.7		 2cmlC-4h53A:
51.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4477_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.51A 2cmlD-2bf6A:
21.3		 2cmlD-2bf6A:
22.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)		 4h53 NEURAMINIDASE
(Influenza
A
virus) 		5 / 8 SER A 367
SER A 370
SER A 372
ASN A 400
TRP A 403
 SIA  A 510 (-2.5A)
SIA  A 510 (-2.6A)
SIA  A 510 (-2.8A)
SIA  A 510 (-3.4A)
SIA  A 510 (-3.5A)
 0.63A 2cmlD-4h53A:
64.7		 2cmlD-4h53A:
51.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F0Z_A_ZMRA381_1
(SIALIDASE 2)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
TYR A 485
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-4.7A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.40A 2f0zA-2bf6A:
44.2		 2f0zA-2bf6A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F10_A_BCZA382_0
(SIALIDASE 2)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		8 / 12 ARG A 266
ILE A 267
ARG A 285
TYR A 485
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-4.5A)
SIA  A1692 (-3.6A)
SIA  A1692 (-4.7A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.57A 2f10A-2bf6A:
43.1		 2f10A-2bf6A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HTQ_A_ZMRA472_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 12 ARG A 266
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.64A 2htqA-2bf6A:
12.8		 2htqA-2bf6A:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5iuc PLATELET BINDING
PROTEIN GSPB
(Streptococcus
gordonii) 		4 / 7 PRO A 474
ILE A 520
GLY A 450
TRP A 453
 None
None
SIA  A 602 ( 4.1A)
None
 0.91A 2y7kA-5iucA:
undetectable		 2y7kA-5iucA:
18.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YA7_A_ZMRA1776_1
(NEURAMINIDASE A)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 12 ARG A 266
ILE A 267
ASP A 283
ILE A 297
ARG A 615
 SIA  A1692 (-2.7A)
SIA  A1692 (-4.5A)
None
None
SIA  A1692 (-3.1A)
 1.40A 2ya7A-2bf6A:
57.0		 2ya7A-2bf6A:
43.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YA7_A_ZMRA1776_1
(NEURAMINIDASE A)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		10 / 12 ARG A 266
ILE A 267
ASP A 283
ILE A 327
ASP A 328
TYR A 485
GLN A 493
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-4.5A)
None
SIA  A1692 (-4.5A)
SIA  A1692 (-2.9A)
SIA  A1692 (-4.7A)
SIA  A1692 (-3.0A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.35A 2ya7A-2bf6A:
57.0		 2ya7A-2bf6A:
43.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YA7_A_ZMRA1776_1
(NEURAMINIDASE A)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 12 ARG A 285
ILE A 267
ASP A 328
TYR A 485
GLN A 493
 SIA  A1692 (-3.6A)
SIA  A1692 (-4.5A)
SIA  A1692 (-2.9A)
SIA  A1692 (-4.7A)
SIA  A1692 (-3.0A)
 1.22A 2ya7A-2bf6A:
57.0		 2ya7A-2bf6A:
43.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YA7_B_ZMRB1776_1
(NEURAMINIDASE A)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 12 ARG A 266
ILE A 267
ASP A 283
ILE A 297
ARG A 615
 SIA  A1692 (-2.7A)
SIA  A1692 (-4.5A)
None
None
SIA  A1692 (-3.1A)
 1.38A 2ya7B-2bf6A:
56.7		 2ya7B-2bf6A:
43.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YA7_B_ZMRB1776_1
(NEURAMINIDASE A)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		10 / 12 ARG A 266
ILE A 267
ASP A 283
ILE A 327
ASP A 328
TYR A 485
GLN A 493
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-4.5A)
None
SIA  A1692 (-4.5A)
SIA  A1692 (-2.9A)
SIA  A1692 (-4.7A)
SIA  A1692 (-3.0A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.36A 2ya7B-2bf6A:
56.7		 2ya7B-2bf6A:
43.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YA7_B_ZMRB1776_1
(NEURAMINIDASE A)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 12 ARG A 285
ILE A 267
ASP A 328
TYR A 485
GLN A 493
 SIA  A1692 (-3.6A)
SIA  A1692 (-4.5A)
SIA  A1692 (-2.9A)
SIA  A1692 (-4.7A)
SIA  A1692 (-3.0A)
 1.20A 2ya7B-2bf6A:
56.7		 2ya7B-2bf6A:
43.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YA7_C_ZMRC1776_1
(NEURAMINIDASE A)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 12 ARG A 266
ILE A 267
ASP A 283
ILE A 297
ARG A 615
 SIA  A1692 (-2.7A)
SIA  A1692 (-4.5A)
None
None
SIA  A1692 (-3.1A)
 1.36A 2ya7C-2bf6A:
52.3		 2ya7C-2bf6A:
43.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YA7_C_ZMRC1776_1
(NEURAMINIDASE A)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		9 / 12 ARG A 266
ILE A 267
ASP A 283
ILE A 327
ASP A 328
TYR A 485
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-4.5A)
None
SIA  A1692 (-4.5A)
SIA  A1692 (-2.9A)
SIA  A1692 (-4.7A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.34A 2ya7C-2bf6A:
52.3		 2ya7C-2bf6A:
43.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YA7_C_ZMRC1776_2
(NEURAMINIDASE A)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		4 / 6 ASP A 291
GLN A 493
GLU A 539
TYR A 587
 SIA  A1692 (-2.8A)
SIA  A1692 (-3.0A)
SIA  A1692 ( 3.9A)
None
 0.28A 2ya7C-2bf6A:
52.3		 2ya7C-2bf6A:
43.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YA7_D_ZMRD1776_1
(NEURAMINIDASE A)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 12 ARG A 266
ILE A 267
ASP A 283
ILE A 297
ARG A 615
 SIA  A1692 (-2.7A)
SIA  A1692 (-4.5A)
None
None
SIA  A1692 (-3.1A)
 1.38A 2ya7D-2bf6A:
56.6		 2ya7D-2bf6A:
43.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YA7_D_ZMRD1776_1
(NEURAMINIDASE A)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		10 / 12 ARG A 266
ILE A 267
ASP A 283
ILE A 327
ASP A 328
TYR A 485
GLN A 493
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-4.5A)
None
SIA  A1692 (-4.5A)
SIA  A1692 (-2.9A)
SIA  A1692 (-4.7A)
SIA  A1692 (-3.0A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.35A 2ya7D-2bf6A:
56.6		 2ya7D-2bf6A:
43.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YA7_D_ZMRD1776_1
(NEURAMINIDASE A)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 12 ARG A 285
ILE A 267
ASP A 328
TYR A 485
GLN A 493
 SIA  A1692 (-3.6A)
SIA  A1692 (-4.5A)
SIA  A1692 (-2.9A)
SIA  A1692 (-4.7A)
SIA  A1692 (-3.0A)
 1.20A 2ya7D-2bf6A:
56.6		 2ya7D-2bf6A:
43.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_B_CL9B401_2
(DEOXYCYTIDINE KINASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		4 / 4 ARG A 266
ASP A 283
LEU A 669
ARG A 555
 SIA  A1692 (-2.7A)
None
None
SIA  A1692 (-2.9A)
 1.36A 2ziaB-2bf6A:
undetectable		 2ziaB-2bf6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7E_A_ZMRA1001_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.58A 3b7eA-2bf6A:
21.3		 3b7eA-2bf6A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7E_B_ZMRB1002_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.57A 3b7eB-2bf6A:
21.4		 3b7eB-2bf6A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA2_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 4jtv HEMAGGLUTININ
(Influenza
A
virus) 		3 / 3 LYS A 148
LYS A 136
VAL A 138
 SIA  A 605 (-3.3A)
None
None
 0.70A 3brfA-4jtvA:
undetectable		 3brfA-4jtvA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKZ_A_ZMRA469_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 12 ARG A 266
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.43A 3ckzA-2bf6A:
12.9		 3ckzA-2bf6A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_0
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
 0.54A 3k37B-2bf6A:
24.9		 3k37B-2bf6A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_B_BCZB1001_0
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-4.2A)
 0.43A 3k39B-2bf6A:
24.9		 3k39B-2bf6A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_A_ZMRA901_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 12 ARG A 266
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.43A 3sanA-2bf6A:
4.4		 3sanA-2bf6A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_B_ZMRB901_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 12 ARG A 266
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.43A 3sanB-2bf6A:
22.1		 3sanB-2bf6A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI5_A_ZMRA1002_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.53A 3ti5A-2bf6A:
12.5		 3ti5A-2bf6A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI5_B_ZMRB1002_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.55A 3ti5B-2bf6A:
21.4		 3ti5B-2bf6A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.49A 3ticA-2bf6A:
8.6		 3ticA-2bf6A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_B_ZMRB1002_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.53A 3ticB-2bf6A:
21.4		 3ticB-2bf6A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_C_ZMRC1002_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.50A 3ticC-2bf6A:
8.9		 3ticC-2bf6A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_D_ZMRD1002_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.50A 3ticD-2bf6A:
21.3		 3ticD-2bf6A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 2v73 PUTATIVE
EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		4 / 7 ILE A  40
ILE A 110
SER A  53
GLU A  79
 None
None
None
SIA  A1190 (-3.1A)
 0.59A 3ua5B-2v73A:
undetectable		 3ua5B-2v73A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 5fre EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		4 / 7 ILE A  35
ILE A 111
SER A  48
GLU A  74
 None
None
None
SIA  A 201 (-3.1A)
 0.64A 3ua5B-5freA:
undetectable		 3ua5B-5freA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		4 / 6 ARG A 615
LEU A 590
PRO A 610
GLU A 585
 SIA  A1692 (-3.1A)
None
None
None
 1.19A 3vlnA-2bf6A:
undetectable		 3vlnA-2bf6A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_A_NCAA1359_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 5m63 H CHAIN OF FAB
NVS-1-19-5
L CHAIN OF FAB
NVS-1-19-5
(Oryctolagus
cuniculus;
Oryctolagus
cuniculus) 		4 / 7 THR L 123
TRP H  65
HIS H 127
ASN L 118
 None
None
SIA  H 306 ( 3.7A)
None
 1.24A 4a3uA-5m63L:
undetectable		 4a3uA-5m63L:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_A_NCAA1536_0
(DIPHTHERIA TOXIN)		 6er3 BNR/ASP-BOX REPEAT
PROTEIN
([Ruminococcus]
gnavus) 		4 / 6 GLY A 160
TYR A  75
TYR A 169
GLU A  85
 None
SIA  A 201 ( 4.4A)
None
SIA  A 201 (-3.1A)
 1.00A 4ae1A-6er3A:
undetectable		 4ae1A-6er3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.57A 4b7nA-2bf6A:
21.3		 4b7nA-2bf6A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.65A 4b7qA-2bf6A:
21.4		 4b7qA-2bf6A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_B_ZMRB601_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.61A 4b7qB-2bf6A:
21.3		 4b7qB-2bf6A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.57A 4b7qC-2bf6A:
21.2		 4b7qC-2bf6A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_D_ZMRD601_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.64A 4b7qD-2bf6A:
12.5		 4b7qD-2bf6A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_A_ZMRA700_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.54A 4cpnA-2bf6A:
24.9		 4cpnA-2bf6A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_B_ZMRB700_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.54A 4cpnB-2bf6A:
25.1		 4cpnB-2bf6A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_A_ZMRA1471_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 12 ARG A 266
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.39A 4cpzA-2bf6A:
25.0		 4cpzA-2bf6A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_B_ZMRB1471_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 12 ARG A 266
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.36A 4cpzB-2bf6A:
25.0		 4cpzB-2bf6A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.55A 4cpzC-2bf6A:
5.8		 4cpzC-2bf6A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_D_ZMRD1471_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 12 ARG A 266
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.33A 4cpzD-2bf6A:
25.0		 4cpzD-2bf6A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.58A 4cpzE-2bf6A:
25.0		 4cpzE-2bf6A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.56A 4cpzF-2bf6A:
24.9		 4cpzF-2bf6A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.50A 4cpzG-2bf6A:
25.1		 4cpzG-2bf6A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.57A 4cpzH-2bf6A:
24.9		 4cpzH-2bf6A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5xl6 HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 LEU A 191
TYR A 192
ILE A 249
GLY A 130
 SIA  A 603 (-4.7A)
None
None
SIA  A 603 ( 4.4A)
 0.93A 4eq4A-5xl6A:
undetectable		 4eq4A-5xl6A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5xl6 HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 LEU A 191
TYR A 192
ILE A 249
GLY A 130
 SIA  A 603 (-4.7A)
None
None
SIA  A 603 ( 4.4A)
 0.93A 4eqlA-5xl6A:
undetectable		 4eqlA-5xl6A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5xl6 HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 LEU A 191
TYR A 192
ILE A 249
GLY A 130
 SIA  A 603 (-4.7A)
None
None
SIA  A 603 ( 4.4A)
 0.95A 4eqlB-5xl6A:
undetectable		 4eqlB-5xl6A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 5xl6 HEMAGGLUTININ
(Influenza
A
virus) 		4 / 8 GLY A 215
GLY A 225
GLU A 187
LEU A 223
 None
SIA  A 603 ( 4.4A)
SIA  A 603 (-3.1A)
SIA  A 603 (-4.3A)
 0.88A 4fgzB-5xl6A:
undetectable		 4fgzB-5xl6A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.49A 4i00A-2bf6A:
21.7		 4i00A-2bf6A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5xl6 HEMAGGLUTININ
(Influenza
A
virus) 		4 / 6 LEU A 191
TYR A 192
ILE A 249
GLY A 130
 SIA  A 603 (-4.7A)
None
None
SIA  A 603 ( 4.4A)
 0.91A 4l39A-5xl6A:
undetectable		 4l39A-5xl6A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5xl6 HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 LEU A 191
TYR A 192
ILE A 249
GLY A 130
 SIA  A 603 (-4.7A)
None
None
SIA  A 603 ( 4.4A)
 0.90A 4l39B-5xl6A:
undetectable		 4l39B-5xl6A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		4 / 7 TYR A 485
ILE A 498
ILE A 509
ALA A 496
 SIA  A1692 (-4.7A)
None
None
None
 0.87A 4lv9A-2bf6A:
undetectable		 4lv9A-2bf6A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 12 ARG A 266
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.44A 4mwrA-2bf6A:
21.2		 4mwrA-2bf6A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.53A 4mwxA-2bf6A:
21.3		 4mwxA-2bf6A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		3 / 3 ARG A 266
ASP A 291
ARG A 615
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 (-3.1A)
 0.47A 4mx0A-2bf6A:
9.2		 4mx0A-2bf6A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 1sie POLYOMAVIRUS COAT
PROTEIN VP1
(Mus
musculus
polyomavirus
1) 		3 / 3 PRO A 144
VAL A 290
HIS A 298
 None
None
SIA  A 384 (-3.6A)
 0.83A 4pevC-1sieA:
undetectable		 4pevC-1sieA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WA5_A_ZMRA501_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.68A 4wa5A-2bf6A:
10.2		 4wa5A-2bf6A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_C_QDNC602_1
(CYTOCHROME P450 2D6)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 11 GLY A 462
GLU A 539
PHE A 347
ALA A 292
ASP A 291
 None
SIA  A1692 ( 3.9A)
None
None
SIA  A1692 (-2.8A)
 1.37A 4wnuC-2bf6A:
undetectable		 4wnuC-2bf6A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4rco PUTATIVE
UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 12 ILE A 300
LEU A 242
ILE A 268
ARG A 250
ILE A 303
 None
SIA  A 404 (-4.9A)
None
None
None
 1.05A 4x5jA-4rcoA:
undetectable		 4x5jA-4rcoA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1mco IGG1 MCG INTACT
ANTIBODY (HEAVY
CHAIN)
(Homo
sapiens) 		5 / 11 ASP H 265
VAL H 264
VAL H 269
LEU H 291
THR H 292
 None
None
None
None
SIA  H 436 (-4.0A)
 1.42A 4yhaC-1mcoH:
undetectable		 4yhaC-1mcoH:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CU6_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5wht PUTATIVE
PERTUSSIS-LIKE TOXIN
SUBUNIT
(Salmonella
enterica) 		4 / 6 TYR A  34
ILE A  55
VAL A 103
ALA A  69
 SIA  A 201 ( 4.2A)
None
None
None
 0.90A 5cu6A-5whtA:
undetectable		 5cu6A-5whtA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 5fre EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 12 LEU A 109
ASN A 122
TYR A  65
VAL A  37
HIS A  93
 None
None
SIA  A 201 (-4.0A)
None
SIA  A 201 ( 4.8A)
 1.41A 5d0yA-5freA:
undetectable		 5d0yA-5freA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_B_FOLB201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 5fre EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 12 LEU A 109
ASN A 122
TYR A  65
VAL A  37
HIS A  93
 None
None
SIA  A 201 (-4.0A)
None
SIA  A 201 ( 4.8A)
 1.41A 5d0yB-5freA:
undetectable		 5d0yB-5freA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L17_A_ZMRA512_1
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		6 / 12 ARG A 266
ASP A 291
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.49A 5l17A-2bf6A:
21.1		 5l17A-2bf6A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_1
(METHYLTRANSFERASE)		 2wbv FIBER PROTEIN
(Canine
mastadenovirus
A) 		4 / 7 LEU A 512
PHE A 514
SER A 419
ILE A 477
 None
None
SIA  A1545 (-4.4A)
None
 1.06A 5n5dA-2wbvA:
undetectable		 5n5dA-2wbvA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1401_2
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 9 GLN A 536
GLN A 493
ILE A 267
GLY A 559
SER A 558
 None
SIA  A1692 (-3.0A)
SIA  A1692 (-4.5A)
None
None
 1.31A 5x7pB-2bf6A:
0.9		 5x7pB-2bf6A:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1401_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 9 GLN A 536
GLN A 493
ILE A 267
GLY A 559
SER A 558
 None
SIA  A1692 (-3.0A)
SIA  A1692 (-4.5A)
None
None
 1.38A 5x7pA-2bf6A:
1.4		 5x7pA-2bf6A:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_C_DAHC60_1
(PUTATIVE CYTOCHROME
C)		 4d63 FIBER KNOB DOMAIN
(Turkey
siadenovirus
A) 		4 / 6 MET A 427
ASN A 422
VAL A 420
LEU A 418
 None
SIA  A1455 (-4.5A)
SIA  A1455 (-4.4A)
None
 1.14A 5xdhA-4d63A:
undetectable
5xdhC-4d63A:
undetectable		 5xdhA-4d63A:
22.39
5xdhC-4d63A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4en8 HEMAGGLUTININ
COMPONENTS
HA-22/23/53
(Clostridium
botulinum) 		3 / 3 TYR B 536
ARG B 525
THR B 508
 None
SIA  B 701 (-3.0A)
None
 0.73A 5z84J-4en8B:
undetectable		 5z84J-4en8B:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_1
(SIALIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		7 / 12 ARG A 266
ILE A 267
ARG A 285
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-4.5A)
SIA  A1692 (-3.6A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.39A 6ekuA-2bf6A:
44.2		 6ekuA-2bf6A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_1
(SIALIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		7 / 12 ARG A 266
ILE A 267
ASP A 328
GLU A 539
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-4.5A)
SIA  A1692 (-2.9A)
SIA  A1692 ( 3.9A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.67A 6ekuA-2bf6A:
44.2		 6ekuA-2bf6A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 4nfd PAIRED
IMMUNOGLOBULIN-LIKE
TYPE 2 RECEPTOR BETA
(Homo
sapiens) 		4 / 5 ARG A  96
TYR A   3
GLN A 110
ILE A 112
 SIA  A 201 (-3.0A)
SIA  A 201 (-3.4A)
None
None
 1.25A 6f6sA-4nfdA:
undetectable
6f6sB-4nfdA:
undetectable		 6f6sA-4nfdA:
20.83
6f6sB-4nfdA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_0
(NEURAMINIDASE)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 12 ARG A 266
ASP A 291
ARG A 555
ARG A 615
TYR A 655
 SIA  A1692 (-2.7A)
SIA  A1692 (-2.8A)
SIA  A1692 (-2.9A)
SIA  A1692 (-3.1A)
SIA  A1692 (-4.2A)
 0.53A 6hcxA-2bf6A:
21.2		 6hcxA-2bf6A:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MHT_D_SAMD328_0
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI)		 2bf6 EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 12 GLY A 466
ASP A 328
ILE A 498
SER A 591
VAL A 592
 None
SIA  A1692 (-2.9A)
None
None
None
 1.11A 6mhtA-2bf6A:
undetectable		 6mhtA-2bf6A:
22.78