SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'SHV'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 1po8 PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		4 / 8 LEU A   2
GLY A  30
HIS A  48
PHE A 101
 None
SHV  A 122 ( 3.7A)
SHV  A 122 (-4.1A)
None
 0.62A 1sv9A-1po8A:
17.4		 1sv9A-1po8A:
38.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 1po8 PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		5 / 7 GLY A  30
HIS A  48
ASP A  49
TYR A  52
PRO A  63
 SHV  A 122 ( 3.7A)
SHV  A 122 (-4.1A)
NA  A 121 (-2.4A)
None
None
 0.71A 1th6A-1po8A:
17.4		 1th6A-1po8A:
38.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 1po8 PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		4 / 7 GLY A  32
HIS A  48
TYR A  52
PRO A  63
 NA  A 121 (-3.3A)
SHV  A 122 (-4.1A)
None
None
 0.97A 1th6A-1po8A:
17.4		 1th6A-1po8A:
38.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 1po8 PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		5 / 12 LEU A   2
GLY A  30
GLY A  32
TYR A  52
PRO A  63
 None
SHV  A 122 ( 3.7A)
NA  A 121 (-3.3A)
None
None
 1.08A 1y4lA-1po8A:
16.8		 1y4lA-1po8A:
39.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Y4L_B_SVRB301_2
(PHOSPHOLIPASE A2
HOMOLOG 2)		 1po8 PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		5 / 11 LEU A   2
LEU A   5
GLY A  32
HIS A  48
TYR A  52
 None
None
NA  A 121 (-3.3A)
SHV  A 122 (-4.1A)
None
 0.51A 1y4lB-1po8A:
17.5		 1y4lB-1po8A:
39.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1po8 PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		5 / 7 GLY A  30
HIS A  48
ASP A  49
TYR A  52
PRO A  63
 SHV  A 122 ( 3.7A)
SHV  A 122 (-4.1A)
NA  A 121 (-2.4A)
None
None
 0.70A 2armA-1po8A:
17.4		 2armA-1po8A:
38.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1po8 PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		4 / 7 GLY A  32
HIS A  48
TYR A  52
PRO A  63
 NA  A 121 (-3.3A)
SHV  A 122 (-4.1A)
None
None
 1.00A 2armA-1po8A:
17.4		 2armA-1po8A:
38.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 1po8 PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		5 / 11 ILE A   9
TYR A  25
GLY A  30
LEU A  41
PHE A 101
 None
None
SHV  A 122 ( 3.7A)
None
None
 0.32A 2azyA-1po8A:
17.7		 2azyA-1po8A:
53.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 1po8 PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		5 / 11 ILE A   9
TYR A  25
GLY A  30
LEU A  41
TYR A 106
 None
None
SHV  A 122 ( 3.7A)
None
None
 0.58A 2azyA-1po8A:
17.7		 2azyA-1po8A:
53.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2B17_A_DIFA701_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1po8 PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		5 / 10 LEU A   2
GLY A  30
HIS A  48
ASP A  49
PHE A 101
 None
SHV  A 122 ( 3.7A)
SHV  A 122 (-4.1A)
NA  A 121 (-2.4A)
None
 0.57A 2b17A-1po8A:
17.4		 2b17A-1po8A:
38.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1po8 PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		4 / 6 LEU A   2
HIS A  48
ASP A  49
TYR A  52
 None
SHV  A 122 (-4.1A)
NA  A 121 (-2.4A)
None
 0.41A 2dpzA-1po8A:
17.5		 2dpzA-1po8A:
38.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_A_PPFA3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 1po8 PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		4 / 8 LYS A   1
HIS A  48
ASP A  94
ALA A  55
 None
SHV  A 122 (-4.1A)
None
None
 1.24A 2rk8A-1po8A:
2.0		 2rk8A-1po8A:
10.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FO7_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1po8 PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		4 / 5 HIS A  48
ASP A  49
TYR A  52
PRO A  63
 SHV  A 122 (-4.1A)
NA  A 121 (-2.4A)
None
None
 0.47A 3fo7A-1po8A:
17.4		 3fo7A-1po8A:
38.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H1X_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1po8 PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		4 / 5 HIS A  48
ASP A  49
TYR A  52
PRO A  63
 SHV  A 122 (-4.1A)
NA  A 121 (-2.4A)
None
None
 0.49A 3h1xA-1po8A:
17.4		 3h1xA-1po8A:
38.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CE2_B_SVRB202_2
(-)		 1po8 PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		5 / 12 LEU A   5
GLY A  30
GLY A  32
TYR A  52
PRO A  63
 None
SHV  A 122 ( 3.7A)
NA  A 121 (-3.3A)
None
None
 0.87A 6ce2B-1po8A:
16.7		 6ce2B-1po8A:
36.89