SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'SFU'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_D_CCSD47_0
(GLUTATHIONE
S-TRANSFERASE)		 5eo7 PREDICTED PROTEIN
(Aspergillus
oryzae) 		4 / 7 TRP A 271
THR A 293
LEU A 278
LEU A  24
 None
SFU  A 405 ( 4.1A)
None
SFU  A 405 ( 4.1A)
 1.07A 1gtiD-5eo7A:
undetectable		 1gtiD-5eo7A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_D_D16D417_1
(THYMIDYLATE SYNTHASE)		 5eo7 PREDICTED PROTEIN
(Aspergillus
oryzae) 		6 / 12 GLU A 275
TRP A 271
ASN A  19
LEU A  24
LEU A 278
ALA A 267
 None
None
None
SFU  A 405 ( 4.1A)
None
None
 1.40A 1hvyD-5eo7A:
undetectable		 1hvyD-5eo7A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_O_C41O1327_2
(RENIN)		 5eo7 PREDICTED PROTEIN
(Aspergillus
oryzae) 		4 / 8 TYR A  40
SER A  66
THR A 218
LEU A 278
 SFU  A 405 (-3.1A)
None
None
None
 1.10A 2v0zO-5eo7A:
undetectable		 2v0zO-5eo7A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 5eo7 PREDICTED PROTEIN
(Aspergillus
oryzae) 		4 / 7 GLN A 249
HIS A 252
PHE A 220
PRO A 274
 None
None
SFU  A 404 ( 4.2A)
SFU  A 404 ( 4.2A)
 1.39A 3ql6A-5eo7A:
undetectable		 3ql6A-5eo7A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5eo7 PREDICTED PROTEIN
(Aspergillus
oryzae) 		4 / 7 ASN A  46
GLU A  37
TYR A  40
GLU A  41
 None
SFU  A 401 (-2.3A)
SFU  A 405 (-3.1A)
None
 1.22A 4r87I-5eo7A:
undetectable		 4r87I-5eo7A:
19.06