SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'SDT'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2GVC_B_MMZB501_1 (MONOOXYGENASE)	2zi8	PROBABLE BIPHENYL-2,3-DIOL 1,2-DIOXYGENASE BPHC (Mycobacterium tuberculosis)	3 / 3	ASN A 249 TYR A 256 SER A 288	SDT A 702 (-2.9A) None None	0.92A	2gvcB-2zi8A: undetectable	2gvcB-2zi8A: 20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2GVC_E_MMZE501_1 (MONOOXYGENASE)	2zi8	PROBABLE BIPHENYL-2,3-DIOL 1,2-DIOXYGENASE BPHC (Mycobacterium tuberculosis)	3 / 3	ASN A 249 TYR A 256 SER A 288	SDT A 702 (-2.9A) None None	0.93A	2gvcE-2zi8A: undetectable	2gvcE-2zi8A: 20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WKO_F_CUF154_0 (SUPEROXIDE DISMUTASE [CU-ZN])	2zi8	PROBABLE BIPHENYL-2,3-DIOL 1,2-DIOXYGENASE BPHC (Mycobacterium tuberculosis)	4 / 5	HIS A 145 HIS A 200 VAL A 147 HIS A 215	FE2 A 701 ( 3.3A) SDT A 702 (-4.0A) None FE2 A 701 ( 3.3A)	0.92A	2wkoF-2zi8A: undetectable	2wkoF-2zi8A: 20.20