SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'SCN'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 3v48 PUTATIVE
AMINOACRYLATE
HYDROLASE RUTD
(Escherichia
coli) 		3 / 3 ALA A 139
VAL A 141
TRP A 140
 None
None
SCN  A 269 (-4.4A)
 0.77A 1bdwA-3v48A:
undetectable
1bdwB-3v48A:
undetectable		 1bdwA-3v48A:
6.99
1bdwB-3v48A:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 3v48 PUTATIVE
AMINOACRYLATE
HYDROLASE RUTD
(Escherichia
coli) 		3 / 3 ALA A 143
VAL A 141
TRP A 140
 None
None
SCN  A 269 (-4.4A)
 0.89A 1bdwA-3v48A:
undetectable
1bdwB-3v48A:
undetectable		 1bdwA-3v48A:
6.99
1bdwB-3v48A:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 3tl2 MALATE DEHYDROGENASE
(Bacillus
anthracis) 		4 / 8 ILE A 119
MET A 241
VAL A 127
LEU A 276
 None
None
SCN  A 314 (-4.8A)
None
 0.89A 1dzmA-3tl2A:
undetectable		 1dzmA-3tl2A:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3001_0
(BETA-CARBONIC
ANHYDRASE)		 2a5v CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(CARBONIC
DEHYDRATASE)
(Mycobacterium
tuberculosis) 		5 / 8 CYH A  51
ASP A  53
HIS A 104
CYH A 107
GLY A 108
 ZN  A 401 ( 2.3A)
SCN  A 501 (-4.0A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 2.3A)
SCN  A 501 (-4.2A)
 0.19A 1ekjA-2a5vA:
19.4
1ekjB-2a5vA:
19.3		 1ekjA-2a5vA:
29.49
1ekjB-2a5vA:
29.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3001_0
(BETA-CARBONIC
ANHYDRASE)		 2a5v CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(CARBONIC
DEHYDRATASE)
(Mycobacterium
tuberculosis) 		5 / 8 CYH A  51
ASP A  53
HIS A 104
CYH A 107
GLY A 108
 ZN  A 401 ( 2.3A)
SCN  A 501 (-4.0A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 2.3A)
SCN  A 501 (-4.2A)
 1.02A 1ekjA-2a5vA:
19.4
1ekjB-2a5vA:
19.3		 1ekjA-2a5vA:
29.49
1ekjB-2a5vA:
29.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3001_0
(BETA-CARBONIC
ANHYDRASE)		 3vrk CARBONYL SULFIDE
HYDROLASE
(Thiobacillus
thioparus) 		5 / 8 CYH A  44
ASP A  46
HIS A  97
CYH A 100
GLY A 101
 ZN  A 301 (-2.2A)
SCN  A 303 (-4.2A)
ZN  A 301 (-3.2A)
ZN  A 301 (-2.3A)
SCN  A 303 ( 4.2A)
 0.23A 1ekjA-3vrkA:
13.5
1ekjB-3vrkA:
13.7		 1ekjA-3vrkA:
24.69
1ekjB-3vrkA:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3001_0
(BETA-CARBONIC
ANHYDRASE)		 3vrk CARBONYL SULFIDE
HYDROLASE
(Thiobacillus
thioparus) 		5 / 8 CYH A  44
ASP A  46
HIS A  97
CYH A 100
GLY A 101
 ZN  A 301 (-2.2A)
SCN  A 303 (-4.2A)
ZN  A 301 (-3.2A)
ZN  A 301 (-2.3A)
SCN  A 303 ( 4.2A)
 0.91A 1ekjA-3vrkA:
13.5
1ekjB-3vrkA:
13.7		 1ekjA-3vrkA:
24.69
1ekjB-3vrkA:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3003_0
(BETA-CARBONIC
ANHYDRASE)		 2a5v CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(CARBONIC
DEHYDRATASE)
(Mycobacterium
tuberculosis) 		5 / 8 CYH A  51
ASP A  53
HIS A 104
CYH A 107
GLY A 108
 ZN  A 401 ( 2.3A)
SCN  A 501 (-4.0A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 2.3A)
SCN  A 501 (-4.2A)
 0.23A 1ekjA-2a5vA:
19.4
1ekjB-2a5vA:
19.3		 1ekjA-2a5vA:
29.49
1ekjB-2a5vA:
29.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3003_0
(BETA-CARBONIC
ANHYDRASE)		 3vrk CARBONYL SULFIDE
HYDROLASE
(Thiobacillus
thioparus) 		5 / 8 CYH A  44
ASP A  46
HIS A  97
CYH A 100
GLY A 101
 ZN  A 301 (-2.2A)
SCN  A 303 (-4.2A)
ZN  A 301 (-3.2A)
ZN  A 301 (-2.3A)
SCN  A 303 ( 4.2A)
 0.27A 1ekjA-3vrkA:
13.5
1ekjB-3vrkA:
13.7		 1ekjA-3vrkA:
24.69
1ekjB-3vrkA:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)		 2a5v CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(CARBONIC
DEHYDRATASE)
(Mycobacterium
tuberculosis) 		4 / 7 CYH A  51
ASP A  53
HIS A 104
GLY A 108
 ZN  A 401 ( 2.3A)
SCN  A 501 (-4.0A)
ZN  A 401 ( 3.3A)
SCN  A 501 (-4.2A)
 0.18A 1ekjE-2a5vA:
19.1
1ekjF-2a5vA:
19.2		 1ekjE-2a5vA:
29.49
1ekjF-2a5vA:
29.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)		 2a5v CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(CARBONIC
DEHYDRATASE)
(Mycobacterium
tuberculosis) 		4 / 7 CYH A  51
ASP A  53
HIS A 104
GLY A 108
 ZN  A 401 ( 2.3A)
SCN  A 501 (-4.0A)
ZN  A 401 ( 3.3A)
SCN  A 501 (-4.2A)
 0.96A 1ekjE-2a5vA:
19.1
1ekjF-2a5vA:
19.2		 1ekjE-2a5vA:
29.49
1ekjF-2a5vA:
29.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)		 3vrk CARBONYL SULFIDE
HYDROLASE
(Thiobacillus
thioparus) 		4 / 7 ASP A  46
HIS A  97
GLY A  69
GLY A  70
 SCN  A 303 (-4.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 4.3A)
None
 0.84A 1ekjE-3vrkA:
13.2
1ekjF-3vrkA:
13.1		 1ekjE-3vrkA:
24.69
1ekjF-3vrkA:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)		 3vrk CARBONYL SULFIDE
HYDROLASE
(Thiobacillus
thioparus) 		4 / 7 CYH A  44
ASP A  46
HIS A  97
GLY A 101
 ZN  A 301 (-2.2A)
SCN  A 303 (-4.2A)
ZN  A 301 (-3.2A)
SCN  A 303 ( 4.2A)
 0.18A 1ekjE-3vrkA:
13.2
1ekjF-3vrkA:
13.1		 1ekjE-3vrkA:
24.69
1ekjF-3vrkA:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3002_0
(BETA-CARBONIC
ANHYDRASE)		 2a5v CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(CARBONIC
DEHYDRATASE)
(Mycobacterium
tuberculosis) 		5 / 8 CYH A  51
ASP A  53
HIS A 104
CYH A 107
GLY A 108
 ZN  A 401 ( 2.3A)
SCN  A 501 (-4.0A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 2.3A)
SCN  A 501 (-4.2A)
 0.16A 1ekjG-2a5vA:
19.3
1ekjH-2a5vA:
19.3		 1ekjG-2a5vA:
29.49
1ekjH-2a5vA:
29.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3002_0
(BETA-CARBONIC
ANHYDRASE)		 2a5v CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(CARBONIC
DEHYDRATASE)
(Mycobacterium
tuberculosis) 		5 / 8 CYH A  51
ASP A  53
HIS A 104
CYH A 107
GLY A 108
 ZN  A 401 ( 2.3A)
SCN  A 501 (-4.0A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 2.3A)
SCN  A 501 (-4.2A)
 1.00A 1ekjG-2a5vA:
19.3
1ekjH-2a5vA:
19.3		 1ekjG-2a5vA:
29.49
1ekjH-2a5vA:
29.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3002_0
(BETA-CARBONIC
ANHYDRASE)		 3vrk CARBONYL SULFIDE
HYDROLASE
(Thiobacillus
thioparus) 		5 / 8 CYH A  44
ASP A  46
HIS A  97
CYH A 100
GLY A 101
 ZN  A 301 (-2.2A)
SCN  A 303 (-4.2A)
ZN  A 301 (-3.2A)
ZN  A 301 (-2.3A)
SCN  A 303 ( 4.2A)
 0.19A 1ekjG-3vrkA:
13.8
1ekjH-3vrkA:
13.3		 1ekjG-3vrkA:
24.69
1ekjH-3vrkA:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3002_0
(BETA-CARBONIC
ANHYDRASE)		 3vrk CARBONYL SULFIDE
HYDROLASE
(Thiobacillus
thioparus) 		5 / 8 CYH A  44
ASP A  46
HIS A  97
CYH A 100
GLY A 101
 ZN  A 301 (-2.2A)
SCN  A 303 (-4.2A)
ZN  A 301 (-3.2A)
ZN  A 301 (-2.3A)
SCN  A 303 ( 4.2A)
 0.88A 1ekjG-3vrkA:
13.8
1ekjH-3vrkA:
13.3		 1ekjG-3vrkA:
24.69
1ekjH-3vrkA:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_H_ACTH3006_0
(BETA-CARBONIC
ANHYDRASE)		 2a5v CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(CARBONIC
DEHYDRATASE)
(Mycobacterium
tuberculosis) 		4 / 6 CYH A  51
ASP A  53
HIS A 104
CYH A 107
 ZN  A 401 ( 2.3A)
SCN  A 501 (-4.0A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 2.3A)
 0.16A 1ekjG-2a5vA:
19.3
1ekjH-2a5vA:
19.3		 1ekjG-2a5vA:
29.49
1ekjH-2a5vA:
29.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_H_ACTH3006_0
(BETA-CARBONIC
ANHYDRASE)		 3vrk CARBONYL SULFIDE
HYDROLASE
(Thiobacillus
thioparus) 		4 / 6 CYH A  44
ASP A  46
HIS A  97
CYH A 100
 ZN  A 301 (-2.2A)
SCN  A 303 (-4.2A)
ZN  A 301 (-3.2A)
ZN  A 301 (-2.3A)
 0.20A 1ekjG-3vrkA:
13.7
1ekjH-3vrkA:
13.3		 1ekjG-3vrkA:
24.69
1ekjH-3vrkA:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_2
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN)
IGG2B-KAPPA 40-50
FAB (LIGHT CHAIN))		 4eb0 LCC
(uncultured
bacterium) 		4 / 7 THR A 144
SER A 145
ARG A 143
LEU A 181
 SCN  A 303 (-4.7A)
SCN  A 303 (-2.7A)
None
None
 0.94A 1ibgL-4eb0A:
undetectable		 1ibgL-4eb0A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 2wl1 PYRIN
(Homo
sapiens) 		5 / 12 VAL A 587
LEU A 709
HIS A 739
SER A 728
THR A 707
 None
None
None
None
SCN  A1778 ( 4.7A)
 1.11A 1jffB-2wl1A:
undetectable		 1jffB-2wl1A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_1
(ADENOSINE KINASE)		 3uen DNA TOPOISOMERASE
2-BINDING PROTEIN 1
(Homo
sapiens) 		5 / 12 ASP A 621
LEU A 598
GLY A 658
THR A 614
LEU A 633
 None
SCN  A 801 ( 3.9A)
None
SCN  A 801 (-3.9A)
None
 1.06A 1liiA-3uenA:
undetectable		 1liiA-3uenA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2fno AGR_PAT_752P
(Agrobacterium
fabrum) 		3 / 3 ILE A 194
LEU A 197
VAL A 201
 None
None
SCN  A 238 ( 4.4A)
 0.45A 1mz9B-2fnoA:
undetectable		 1mz9B-2fnoA:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_0
(MODIFICATION
METHYLASE RSRI)		 3fkj PUTATIVE
PHOSPHOSUGAR
ISOMERASES
(Salmonella
enterica) 		5 / 12 PHE A 293
GLY A 295
SER A 203
ALA A 138
ALA A 137
 None
None
None
SCN  A 329 ( 4.2A)
SCN  A 329 (-3.6A)
 1.24A 1nw5A-3fkjA:
undetectable		 1nw5A-3fkjA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 5k9h 0940_GH29
(unidentified) 		3 / 3 TRP A 253
VAL A 254
PRO A 255
 None
SCN  A 621 ( 4.9A)
None
 0.27A 1rg1A-5k9hA:
undetectable		 1rg1A-5k9hA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 5k9h 0940_GH29
(unidentified) 		3 / 3 TRP A 253
VAL A 254
PRO A 255
 None
SCN  A 621 ( 4.9A)
None
 0.28A 1rh0A-5k9hA:
undetectable		 1rh0A-5k9hA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SKX_A_RFPA1_2
(ORPHAN NUCLEAR
RECEPTOR PXR)		 5e2g BETA-LACTAMASE
(Burkholderia
cenocepacia) 		4 / 5 PHE A 165
LEU A 101
MET A 161
LEU A 243
 None
None
None
SCN  A 402 ( 4.0A)
 1.42A 1skxA-5e2gA:
undetectable		 1skxA-5e2gA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 3kxi GTP-BINDING PROTEIN
(HFLX)
(Sulfolobus
solfataricus) 		4 / 7 LYS A 321
ILE A 262
ILE A 333
ASP A 329
 None
None
SCN  A 366 (-3.5A)
None
 0.81A 1uwjA-3kxiA:
undetectable		 1uwjA-3kxiA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA502_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 1sq4 GLYOXYLATE-INDUCED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 LEU A 262
HIS A 214
LYS A 264
 SCN  A 302 ( 4.5A)
None
SCN  A 302 ( 3.9A)
 0.99A 1y7iA-1sq4A:
undetectable		 1y7iA-1sq4A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3tl2 MALATE DEHYDROGENASE
(Bacillus
anthracis) 		4 / 5 LEU A 270
ASP A 128
PRO A 254
ILE A 256
 None
SCN  A 314 (-3.7A)
None
None
 0.95A 2aoiB-3tl2A:
undetectable		 2aoiB-3tl2A:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		 2fno AGR_PAT_752P
(Agrobacterium
fabrum) 		6 / 12 LEU A 172
LEU A 112
LEU A 133
ILE A 137
ILE A 187
ALA A 177
 None
None
None
None
SCN  A 237 ( 3.9A)
SCN  A 237 (-3.4A)
 1.34A 2bxqA-2fnoA:
undetectable		 2bxqA-2fnoA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 6 TYR A 144
GLY A 214
TYR A 221
ASP A 212
 None
SCN  A 711 ( 4.4A)
None
None
 1.17A 2g72A-4l37A:
undetectable		 2g72A-4l37A:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 5e2g BETA-LACTAMASE
(Burkholderia
cenocepacia) 		4 / 5 ASP A  71
LEU A  68
MET A 169
ARG A 172
 SCN  A 402 ( 3.7A)
None
None
SCN  A 402 ( 4.7A)
 1.25A 2gj5A-5e2gA:
undetectable		 2gj5A-5e2gA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMA_A_SAMA375_0
(PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE)		 3v48 PUTATIVE
AMINOACRYLATE
HYDROLASE RUTD
(Escherichia
coli) 		5 / 11 GLY A  26
SER A  20
GLY A  24
GLN A 173
PHE A 172
 None
None
None
SCN  A 269 ( 4.8A)
None
 1.28A 2hmaA-3v48A:
undetectable		 2hmaA-3v48A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 2wl1 PYRIN
(Homo
sapiens) 		5 / 12 VAL A 587
LEU A 709
HIS A 739
SER A 728
THR A 707
 None
None
None
None
SCN  A1778 ( 4.7A)
 1.11A 2hxfB-2wl1A:
undetectable		 2hxfB-2wl1A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)		 2wl1 PYRIN
(Homo
sapiens) 		5 / 12 VAL A 587
LEU A 709
HIS A 739
SER A 728
THR A 707
 None
None
None
None
SCN  A1778 ( 4.7A)
 1.11A 2hxhB-2wl1A:
undetectable		 2hxhB-2wl1A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1294_1
(FICOLIN-2)		 3pvz UDP-N-ACETYLGLUCOSAM
INE 4,6-DEHYDRATASE
(Aliivibrio
fischeri) 		5 / 9 GLY A 205
SER A 206
LEU A 208
SER A 203
ASP A 204
 None
SCN  A 604 (-3.7A)
SCN  A 604 ( 3.9A)
NAD  A 501 (-2.9A)
None
 1.27A 2j2pB-3pvzA:
undetectable
2j2pC-3pvzA:
undetectable		 2j2pB-3pvzA:
18.41
2j2pC-3pvzA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 3hk0 GROWTH FACTOR
RECEPTOR-BOUND
PROTEIN 10
(Homo
sapiens) 		4 / 7 LEU A 227
LEU A 223
GLU A 167
ARG A 337
 None
None
None
SCN  A  15 (-3.8A)
 0.98A 2jn3A-3hk0A:
undetectable		 2jn3A-3hk0A:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)		 2wl1 PYRIN
(Homo
sapiens) 		5 / 12 VAL A 587
LEU A 709
HIS A 739
SER A 728
THR A 707
 None
None
None
None
SCN  A1778 ( 4.7A)
 1.11A 2p4nB-2wl1A:
undetectable		 2p4nB-2wl1A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 7 TYR A 221
TYR A 218
PRO A 588
THR A 586
 None
None
SCN  A 711 ( 4.7A)
None
 1.31A 2q6kA-4l37A:
undetectable		 2q6kA-4l37A:
16.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QQT_A_AINA596_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		6 / 6 HIS A  95
ARG A 239
GLU A 242
PHE A 366
GLN A 408
PRO A 409
 SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
HEM  A 605 ( 4.6A)
None
 0.38A 2qqtA-2gjmA:
65.6		 2qqtA-2gjmA:
99.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)		 3tl2 MALATE DEHYDROGENASE
(Bacillus
anthracis) 		4 / 8 VAL A 127
PRO A 126
VAL A 304
SER A 303
 SCN  A 314 (-4.8A)
EDO  A 313 ( 3.7A)
SCN  A 314 ( 3.9A)
None
 0.94A 2v32C-3tl2A:
undetectable
2v32D-3tl2A:
2.3		 2v32C-3tl2A:
22.56
2v32D-3tl2A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		5 / 12 SER A  47
THR A  42
ARG A 290
ILE A 288
PHE A  43
 None
None
SCN  A 404 (-4.1A)
None
None
 1.15A 2vdyA-5bu6A:
undetectable		 2vdyA-5bu6A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)		 2wl1 PYRIN
(Homo
sapiens) 		5 / 12 VAL A 587
LEU A 709
HIS A 739
SER A 728
THR A 707
 None
None
None
None
SCN  A1778 ( 4.7A)
 1.11A 2wbeB-2wl1A:
undetectable		 2wbeB-2wl1A:
17.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y7K_A_SALA1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2uye REGULATORY PROTEIN
(Burkholderia
cepacia) 		7 / 11 THR A 104
GLY A 107
GLY A 152
PHE A 167
HIS A 206
PRO A 246
ILE A 273
 SCN  A1307 (-4.0A)
SCN  A1303 (-3.5A)
SCN  A1307 (-3.6A)
SCN  A1303 (-4.7A)
SCN  A1307 (-3.6A)
None
SCN  A1303 (-4.1A)
 0.92A 2y7kA-2uyeA:
30.2		 2y7kA-2uyeA:
70.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y7K_A_SALA1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2uye REGULATORY PROTEIN
(Burkholderia
cepacia) 		7 / 11 THR A 104
ILE A 106
GLY A 107
GLY A 152
PHE A 167
PRO A 246
ILE A 273
 SCN  A1307 (-4.0A)
SCN  A1303 ( 4.9A)
SCN  A1303 (-3.5A)
SCN  A1307 (-3.6A)
SCN  A1303 (-4.7A)
None
SCN  A1303 (-4.1A)
 0.86A 2y7kA-2uyeA:
30.2		 2y7kA-2uyeA:
70.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y7K_B_SALB1304_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2uye REGULATORY PROTEIN
(Burkholderia
cepacia) 		6 / 10 THR A 104
GLY A 107
PHE A 167
HIS A 206
PRO A 246
ILE A 273
 SCN  A1307 (-4.0A)
SCN  A1303 (-3.5A)
SCN  A1303 (-4.7A)
SCN  A1307 (-3.6A)
None
SCN  A1303 (-4.1A)
 0.89A 2y7kB-2uyeA:
30.5		 2y7kB-2uyeA:
70.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y7K_B_SALB1304_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2uye REGULATORY PROTEIN
(Burkholderia
cepacia) 		6 / 10 THR A 104
ILE A 106
GLY A 107
PHE A 167
PRO A 246
ILE A 273
 SCN  A1307 (-4.0A)
SCN  A1303 ( 4.9A)
SCN  A1303 (-3.5A)
SCN  A1303 (-4.7A)
None
SCN  A1303 (-4.1A)
 0.82A 2y7kB-2uyeA:
30.5		 2y7kB-2uyeA:
70.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y7K_C_SALC1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2uye REGULATORY PROTEIN
(Burkholderia
cepacia) 		5 / 12 GLY A 152
PHE A 167
HIS A 169
PRO A 246
ILE A 273
 SCN  A1307 (-3.6A)
SCN  A1303 (-4.7A)
SCN  A1303 (-4.4A)
None
SCN  A1303 (-4.1A)
 1.22A 2y7kC-2uyeA:
32.6		 2y7kC-2uyeA:
70.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y7K_C_SALC1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2uye REGULATORY PROTEIN
(Burkholderia
cepacia) 		8 / 12 THR A 104
ILE A 106
GLY A 107
GLY A 152
PHE A 167
HIS A 206
PRO A 246
ILE A 273
 SCN  A1307 (-4.0A)
SCN  A1303 ( 4.9A)
SCN  A1303 (-3.5A)
SCN  A1307 (-3.6A)
SCN  A1303 (-4.7A)
SCN  A1307 (-3.6A)
None
SCN  A1303 (-4.1A)
 0.77A 2y7kC-2uyeA:
32.6		 2y7kC-2uyeA:
70.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y7K_D_SALD1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2uye REGULATORY PROTEIN
(Burkholderia
cepacia) 		5 / 12 GLY A 152
PHE A 167
HIS A 169
PRO A 246
ILE A 273
 SCN  A1307 (-3.6A)
SCN  A1303 (-4.7A)
SCN  A1303 (-4.4A)
None
SCN  A1303 (-4.1A)
 1.23A 2y7kD-2uyeA:
31.6		 2y7kD-2uyeA:
70.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y7K_D_SALD1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2uye REGULATORY PROTEIN
(Burkholderia
cepacia) 		8 / 12 THR A 104
ILE A 106
GLY A 107
GLY A 152
PHE A 167
HIS A 206
PRO A 246
ILE A 273
 SCN  A1307 (-4.0A)
SCN  A1303 ( 4.9A)
SCN  A1303 (-3.5A)
SCN  A1307 (-3.6A)
SCN  A1303 (-4.7A)
SCN  A1307 (-3.6A)
None
SCN  A1303 (-4.1A)
 0.71A 2y7kD-2uyeA:
31.6		 2y7kD-2uyeA:
70.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y7P_A_SALA1000_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2uye REGULATORY PROTEIN
(Burkholderia
cepacia) 		5 / 10 GLY A 152
PHE A 167
HIS A 169
PRO A 246
ILE A 273
 SCN  A1307 (-3.6A)
SCN  A1303 (-4.7A)
SCN  A1303 (-4.4A)
None
SCN  A1303 (-4.1A)
 1.31A 2y7pA-2uyeA:
30.1		 2y7pA-2uyeA:
70.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y7P_A_SALA1000_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2uye REGULATORY PROTEIN
(Burkholderia
cepacia) 		7 / 10 THR A 104
GLY A 107
GLY A 152
PHE A 167
HIS A 206
PRO A 246
ILE A 273
 SCN  A1307 (-4.0A)
SCN  A1303 (-3.5A)
SCN  A1307 (-3.6A)
SCN  A1303 (-4.7A)
SCN  A1307 (-3.6A)
None
SCN  A1303 (-4.1A)
 0.94A 2y7pA-2uyeA:
30.1		 2y7pA-2uyeA:
70.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y7P_A_SALA1000_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2uye REGULATORY PROTEIN
(Burkholderia
cepacia) 		7 / 10 THR A 104
ILE A 106
GLY A 107
GLY A 152
PHE A 167
PRO A 246
ILE A 273
 SCN  A1307 (-4.0A)
SCN  A1303 ( 4.9A)
SCN  A1303 (-3.5A)
SCN  A1307 (-3.6A)
SCN  A1303 (-4.7A)
None
SCN  A1303 (-4.1A)
 0.92A 2y7pA-2uyeA:
30.1		 2y7pA-2uyeA:
70.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y7W_A_SALA1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2uye REGULATORY PROTEIN
(Burkholderia
cepacia) 		6 / 9 THR A 104
ILE A 106
GLY A 107
GLY A 152
PHE A 167
ILE A 273
 SCN  A1307 (-4.0A)
SCN  A1303 ( 4.9A)
SCN  A1303 (-3.5A)
SCN  A1307 (-3.6A)
SCN  A1303 (-4.7A)
SCN  A1303 (-4.1A)
 0.59A 2y7wA-2uyeA:
20.4		 2y7wA-2uyeA:
73.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y7W_B_SALB1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2uye REGULATORY PROTEIN
(Burkholderia
cepacia) 		6 / 10 THR A 104
GLY A 107
GLY A 152
HIS A 206
PRO A 246
ILE A 273
 SCN  A1307 (-4.0A)
SCN  A1303 (-3.5A)
SCN  A1307 (-3.6A)
SCN  A1307 (-3.6A)
None
SCN  A1303 (-4.1A)
 0.74A 2y7wB-2uyeA:
30.7		 2y7wB-2uyeA:
73.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y7W_B_SALB1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2uye REGULATORY PROTEIN
(Burkholderia
cepacia) 		6 / 10 THR A 104
GLY A 107
THR A 204
HIS A 206
PRO A 246
ILE A 273
 SCN  A1307 (-4.0A)
SCN  A1303 (-3.5A)
SCN  A1309 ( 4.7A)
SCN  A1307 (-3.6A)
None
SCN  A1303 (-4.1A)
 0.90A 2y7wB-2uyeA:
30.7		 2y7wB-2uyeA:
73.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y7W_B_SALB1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2uye REGULATORY PROTEIN
(Burkholderia
cepacia) 		6 / 10 THR A 104
ILE A 106
GLY A 107
GLY A 152
PRO A 246
ILE A 273
 SCN  A1307 (-4.0A)
SCN  A1303 ( 4.9A)
SCN  A1303 (-3.5A)
SCN  A1307 (-3.6A)
None
SCN  A1303 (-4.1A)
 0.33A 2y7wB-2uyeA:
30.7		 2y7wB-2uyeA:
73.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y7W_B_SALB1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2uye REGULATORY PROTEIN
(Burkholderia
cepacia) 		6 / 10 THR A 104
ILE A 106
GLY A 107
THR A 204
PRO A 246
ILE A 273
 SCN  A1307 (-4.0A)
SCN  A1303 ( 4.9A)
SCN  A1303 (-3.5A)
SCN  A1309 ( 4.7A)
None
SCN  A1303 (-4.1A)
 0.56A 2y7wB-2uyeA:
30.7		 2y7wB-2uyeA:
73.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y7W_C_SALC1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2uye REGULATORY PROTEIN
(Burkholderia
cepacia) 		5 / 7 THR A 104
ILE A 106
GLY A 107
PHE A 167
ILE A 273
 SCN  A1307 (-4.0A)
SCN  A1303 ( 4.9A)
SCN  A1303 (-3.5A)
SCN  A1303 (-4.7A)
SCN  A1303 (-4.1A)
 0.64A 2y7wC-2uyeA:
30.7		 2y7wC-2uyeA:
73.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YDO_A_ADNA400_1
(ADENOSINE RECEPTOR
A2A)		 2uye REGULATORY PROTEIN
(Burkholderia
cepacia) 		5 / 12 LEU A 151
THR A 104
PHE A 167
GLU A 300
HIS A 206
 None
SCN  A1307 (-4.0A)
SCN  A1303 (-4.7A)
None
SCN  A1307 (-3.6A)
 0.98A 2ydoA-2uyeA:
undetectable		 2ydoA-2uyeA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4eb0 LCC
(uncultured
bacterium) 		5 / 12 GLN A 134
PHE A 125
ASN A 120
GLY A  72
ARG A  65
 None
SCN  A 302 ( 4.8A)
None
None
None
 1.37A 3aodC-4eb0A:
undetectable		 3aodC-4eb0A:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 2uye REGULATORY PROTEIN
(Burkholderia
cepacia) 		4 / 8 LEU A 151
ILE A 273
HIS A 169
GLY A 205
 None
SCN  A1303 (-4.1A)
SCN  A1303 (-4.4A)
SCN  A1307 (-3.5A)
 0.96A 3b9lA-2uyeA:
undetectable		 3b9lA-2uyeA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 5k9h 0940_GH29
(unidentified) 		3 / 3 TYR A 286
GLU A 360
ASP A 362
 SCN  A 624 ( 4.7A)
None
None
 0.87A 3bxoB-5k9hA:
undetectable		 3bxoB-5k9hA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX94_0
(PROTEIN S100-B)		 2uye REGULATORY PROTEIN
(Burkholderia
cepacia) 		3 / 3 PHE A 249
CYH A 253
PHE A 257
 SCN  A1305 (-4.8A)
SCN  A1305 ( 4.1A)
None
 1.13A 3cr5X-2uyeA:
undetectable		 3cr5X-2uyeA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)		 2wl1 PYRIN
(Homo
sapiens) 		5 / 12 VAL A 587
LEU A 709
HIS A 739
SER A 728
THR A 707
 None
None
None
None
SCN  A1778 ( 4.7A)
 1.11A 3dcoB-2wl1A:
undetectable		 3dcoB-2wl1A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)		 2wl1 PYRIN
(Homo
sapiens) 		5 / 12 VAL A 587
LEU A 709
HIS A 739
SER A 728
THR A 707
 None
None
None
None
SCN  A1778 ( 4.7A)
 1.10A 3edlB-2wl1A:
undetectable		 3edlB-2wl1A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 2a5v CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(CARBONIC
DEHYDRATASE)
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 108
GLY A 103
GLY A  76
PHE A  20
ASP A  53
 SCN  A 501 (-4.2A)
None
ZN  A 401 ( 4.4A)
None
SCN  A 501 (-4.0A)
 0.90A 3elwA-2a5vA:
undetectable		 3elwA-2a5vA:
24.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		6 / 6 HIS A  95
ARG A 239
GLU A 242
PHE A 366
GLN A 408
PRO A 409
 SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
HEM  A 605 ( 4.6A)
None
 0.52A 3gclA-2gjmA:
61.4		 3gclA-2gjmA:
99.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 4a6u OMEGA TRANSAMINASE
(Chromobacterium
violaceum) 		5 / 12 SER A 291
GLY A 293
GLY A 120
GLY A 298
GLY A 289
 None
SCN  A 602 ( 4.8A)
None
None
None
 0.92A 3gczA-4a6uA:
undetectable		 3gczA-4a6uA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_A_SAMA401_0
(O-METHYLTRANSFERASE)		 3v48 PUTATIVE
AMINOACRYLATE
HYDROLASE RUTD
(Escherichia
coli) 		5 / 12 PHE A 125
HIS A 237
LEU A 148
GLY A  23
ALA A  88
 None
SCN  A 270 (-3.8A)
GOL  A 267 (-4.7A)
GOL  A 267 ( 3.5A)
SCN  A 270 (-3.3A)
 1.04A 3i5uA-3v48A:
undetectable		 3i5uA-3v48A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_A_0LIA1_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 1sq4 GLYOXYLATE-INDUCED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 LEU A 262
TYR A 260
VAL A  37
ILE A  57
 SCN  A 302 ( 4.5A)
None
None
None
 1.32A 3ik3A-1sq4A:
undetectable		 3ik3A-1sq4A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_B_0LIB2_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 1sq4 GLYOXYLATE-INDUCED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 LEU A 262
TYR A 260
VAL A  37
ILE A  57
 SCN  A 302 ( 4.5A)
None
None
None
 1.28A 3ik3B-1sq4A:
undetectable		 3ik3B-1sq4A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)		 2wl1 PYRIN
(Homo
sapiens) 		5 / 12 VAL A 587
LEU A 709
HIS A 739
SER A 728
THR A 707
 None
None
None
None
SCN  A1778 ( 4.7A)
 1.11A 3iz0B-2wl1A:
undetectable		 3iz0B-2wl1A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6P_B_TA1B502_1
(TUBULIN BETA CHAIN)		 2wl1 PYRIN
(Homo
sapiens) 		5 / 12 VAL A 587
LEU A 709
HIS A 739
SER A 728
THR A 707
 None
None
None
None
SCN  A1778 ( 4.7A)
 1.14A 3j6pB-2wl1A:
undetectable		 3j6pB-2wl1A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 TYR B 222
TYR B 402
TYR B 126
PHE B  81
 None
SCN  B 708 (-4.8A)
None
None
 1.38A 3ku9B-4l37B:
undetectable		 3ku9B-4l37B:
21.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LUS_B_X8ZB1001_1
(ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN)		 6d9n ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Elizabethkingia
anophelis) 		5 / 9 TYR A  32
PRO A  33
PRO A  46
GLU A  47
PHE A  92
 None
None
SCN  A 202 ( 4.3A)
SCN  A 202 (-3.5A)
None
 0.61A 3lusA-6d9nA:
17.0
3lusB-6d9nA:
18.3		 3lusA-6d9nA:
41.46
3lusB-6d9nA:
41.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MES_A_DMEA427_1
(CHOLINE KINASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		5 / 10 SER B 235
GLN B 356
ASN B 358
GLU B 375
TYR B 402
 None
SCN  B 708 (-4.2A)
None
SCN  B 708 (-3.8A)
SCN  B 708 (-4.8A)
 1.41A 3mesA-4l37B:
undetectable		 3mesA-4l37B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MES_B_DMEB427_1
(CHOLINE KINASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		5 / 10 SER B 235
GLN B 356
ASN B 358
GLU B 375
TYR B 402
 None
SCN  B 708 (-4.2A)
None
SCN  B 708 (-3.8A)
SCN  B 708 (-4.8A)
 1.43A 3mesB-4l37B:
undetectable		 3mesB-4l37B:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OGW_A_IMNA597_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		8 / 9 GLN A  91
HIS A  95
PHE A  99
GLU A 102
ARG A 239
GLU A 242
PHE A 366
GLN A 408
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.8A)
None
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
HEM  A 605 ( 4.6A)
 0.50A 3ogwA-2gjmA:
65.8		 3ogwA-2gjmA:
99.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		3 / 3 TYR A 190
ASP A 457
ASP A 560
 None
None
SCN  A 711 (-4.2A)
 0.85A 3ou6B-4l37A:
undetectable		 3ou6B-4l37A:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		3 / 3 TYR A 144
GLY A 214
ASP A 212
 None
SCN  A 711 ( 4.4A)
None
 0.73A 3ou6C-4l37A:
undetectable		 3ou6C-4l37A:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_0
(N-METHYLTRANSFERASE)		 3kxi GTP-BINDING PROTEIN
(HFLX)
(Sulfolobus
solfataricus) 		5 / 12 ALA A 335
GLY A 191
LEU A 336
PHE A 196
SER A 198
 GDP  A 500 (-3.8A)
GDP  A 500 (-3.2A)
GDP  A 500 (-3.9A)
None
SCN  A 366 ( 4.0A)
 1.21A 3pfgA-3kxiA:
2.5		 3pfgA-3kxiA:
20.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PY4_A_TYLA598_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 5 GLN A  91
HIS A  95
ARG A 239
GLU A 242
PHE A 366
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
 0.37A 3py4A-2gjmA:
65.9		 3py4A-2gjmA:
99.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		3 / 3 HIS A  95
ARG A 239
GLU A 242
 SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
 0.45A 3qf1A-2gjmA:
60.5		 3qf1A-2gjmA:
95.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		7 / 7 GLN A  91
HIS A  95
GLU A 102
ARG A 239
GLU A 242
PHE A 366
PRO A 409
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
None
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
None
 0.64A 3ql6A-2gjmA:
60.6		 3ql6A-2gjmA:
99.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R4X_A_PZAA597_0
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 5 GLN A  91
ASP A  94
HIS A  95
ARG A 239
GLU A 242
 HEM  A 605 (-3.4A)
HEM  A 605 (-2.0A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
 0.45A 3r4xA-2gjmA:
60.9		 3r4xA-2gjmA:
99.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R55_A_PZAA597_0
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 5 GLN A  91
ASP A  94
HIS A  95
ARG A 239
GLU A 242
 HEM  A 605 (-3.4A)
HEM  A 605 (-2.0A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
 0.39A 3r55A-2gjmA:
61.1		 3r55A-2gjmA:
95.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TGY_A_ASCA800_0
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		4 / 4 HIS A  95
ARG A 239
GLU A 242
PHE A 366
 SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
 0.50A 3tgyA-2gjmA:
60.1		 3tgyA-2gjmA:
99.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 2a5v CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(CARBONIC
DEHYDRATASE)
(Mycobacterium
tuberculosis) 		7 / 10 CYH A  51
ASP A  53
HIS A 104
CYH A 107
GLY A 108
ALA A 109
ALA A 112
 ZN  A 401 ( 2.3A)
SCN  A 501 (-4.0A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 2.3A)
SCN  A 501 (-4.2A)
SCN  A 501 ( 4.4A)
None
 0.27A 3ucjA-2a5vA:
19.1		 3ucjA-2a5vA:
27.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 2a5v CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(CARBONIC
DEHYDRATASE)
(Mycobacterium
tuberculosis) 		5 / 10 CYH A  51
HIS A 104
CYH A 107
ALA A 109
ALA A 113
 ZN  A 401 ( 2.3A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 2.3A)
SCN  A 501 ( 4.4A)
None
 1.15A 3ucjA-2a5vA:
19.1		 3ucjA-2a5vA:
27.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 3vrk CARBONYL SULFIDE
HYDROLASE
(Thiobacillus
thioparus) 		6 / 10 CYH A  44
ASP A  46
HIS A  97
CYH A 100
GLY A 101
ALA A 104
 ZN  A 301 (-2.2A)
SCN  A 303 (-4.2A)
ZN  A 301 (-3.2A)
ZN  A 301 (-2.3A)
SCN  A 303 ( 4.2A)
None
 1.11A 3ucjA-3vrkA:
13.9		 3ucjA-3vrkA:
28.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 2a5v CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(CARBONIC
DEHYDRATASE)
(Mycobacterium
tuberculosis) 		7 / 10 CYH A  51
ASP A  53
HIS A 104
CYH A 107
GLY A 108
ALA A 109
ALA A 112
 ZN  A 401 ( 2.3A)
SCN  A 501 (-4.0A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 2.3A)
SCN  A 501 (-4.2A)
SCN  A 501 ( 4.4A)
None
 0.27A 3ucjB-2a5vA:
19.8		 3ucjB-2a5vA:
27.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 2a5v CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(CARBONIC
DEHYDRATASE)
(Mycobacterium
tuberculosis) 		5 / 10 CYH A  51
HIS A 104
CYH A 107
ALA A 109
ALA A 113
 ZN  A 401 ( 2.3A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 2.3A)
SCN  A 501 ( 4.4A)
None
 1.15A 3ucjB-2a5vA:
19.8		 3ucjB-2a5vA:
27.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 3vrk CARBONYL SULFIDE
HYDROLASE
(Thiobacillus
thioparus) 		5 / 10 CYH A  44
ASP A  46
HIS A  97
CYH A 100
ALA A 147
 ZN  A 301 (-2.2A)
SCN  A 303 (-4.2A)
ZN  A 301 (-3.2A)
ZN  A 301 (-2.3A)
None
 1.11A 3ucjB-3vrkA:
14.2		 3ucjB-3vrkA:
28.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 3vrk CARBONYL SULFIDE
HYDROLASE
(Thiobacillus
thioparus) 		6 / 10 CYH A  44
ASP A  46
HIS A  97
CYH A 100
GLY A 101
ALA A 104
 ZN  A 301 (-2.2A)
SCN  A 303 (-4.2A)
ZN  A 301 (-3.2A)
ZN  A 301 (-2.3A)
SCN  A 303 ( 4.2A)
None
 1.14A 3ucjB-3vrkA:
14.2		 3ucjB-3vrkA:
28.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 2pa5 TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 9
(Homo
sapiens) 		5 / 12 ILE A 481
ALA A 477
LEU A 535
LEU A 541
ILE A 288
 SCN  A 601 (-3.5A)
SCN  A 601 ( 4.3A)
None
None
None
 0.97A 3uvvA-2pa5A:
undetectable		 3uvvA-2pa5A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 2pa5 TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 9
(Homo
sapiens) 		5 / 12 ILE A 481
ALA A 575
LEU A 535
LEU A 541
ILE A 288
 SCN  A 601 (-3.5A)
None
None
None
None
 0.83A 3uvvA-2pa5A:
undetectable		 3uvvA-2pa5A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZMD_A_SALA201_1
(PUTATIVE
TRANSCRIPTIONAL
REGULATOR)		 3bxh CENTRAL GLYCOLYTIC
GENE REGULATOR
(Bacillus
subtilis) 		4 / 8 LEU A 178
ARG A 251
TYR A 273
GLU A 269
 SCN  A   1 (-4.4A)
F6P  A 401 (-3.7A)
None
F6P  A 401 (-2.9A)
 1.33A 3zmdA-3bxhA:
undetectable
3zmdB-3bxhA:
undetectable		 3zmdA-3bxhA:
18.53
3zmdB-3bxhA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		5 / 12 SER A  47
THR A  42
ARG A 290
ILE A 288
PHE A  43
 None
None
SCN  A 404 (-4.1A)
None
None
 1.22A 4c49C-5bu6A:
undetectable		 4c49C-5bu6A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3tl2 MALATE DEHYDROGENASE
(Bacillus
anthracis) 		5 / 10 GLY A 218
GLY A 217
ASN A 125
VAL A 127
GLN A 148
 None
None
EDO  A 313 ( 4.4A)
SCN  A 314 (-4.8A)
None
 1.47A 4fgkA-3tl2A:
5.1
4fgkB-3tl2A:
5.3		 4fgkA-3tl2A:
21.91
4fgkB-3tl2A:
21.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GN6_A_TYLA621_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		4 / 4 HIS A  95
ARG A 239
GLU A 242
PHE A 366
 SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
 0.39A 4gn6A-2gjmA:
65.0		 4gn6A-2gjmA:
99.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 4pdy AMINOGLYCOSIDE
PHOSPHOTRANSFERASE
(Alicyclobacillus
acidocaldarius) 		4 / 7 LEU A 299
LYS A 334
PHE A 338
GLY A 271
 None
None
None
SCN  A 409 ( 4.7A)
 1.06A 4hbfA-4pdyA:
undetectable		 4hbfA-4pdyA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 4pdy AMINOGLYCOSIDE
PHOSPHOTRANSFERASE
(Alicyclobacillus
acidocaldarius) 		4 / 7 LEU A 299
LYS A 334
PHE A 338
GLY A 271
 None
None
None
SCN  A 409 ( 4.7A)
 1.01A 4hc3A-4pdyA:
undetectable		 4hc3A-4pdyA:
10.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG5_A_MMZA616_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 5 GLN A  91
HIS A  95
ARG A 239
GLU A 242
LEU A 246
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
 0.43A 4ig5A-2gjmA:
59.5		 4ig5A-2gjmA:
95.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG5_B_MMZB617_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 5 GLN A  91
HIS A  95
ARG A 239
GLU A 242
LEU A 246
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
 0.37A 4ig5B-2gjmA:
60.0		 4ig5B-2gjmA:
95.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		3 / 3 GLN A  91
HIS A  95
ARG A 239
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
 0.40A 4qyqA-2gjmA:
59.2		 4qyqA-2gjmA:
95.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		3 / 3 GLN A  91
HIS A  95
ARG A 239
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
 0.30A 4qyqB-2gjmA:
58.9		 4qyqB-2gjmA:
95.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QYQ_C_3CJC607_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		6 / 6 GLN A  91
ASP A  94
HIS A  95
ARG A 239
GLU A 242
ARG A 333
 HEM  A 605 (-3.4A)
HEM  A 605 (-2.0A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
HEM  A 605 (-2.8A)
 0.56A 4qyqC-2gjmA:
27.2		 4qyqC-2gjmA:
95.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QYQ_D_3CJD607_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		4 / 4 GLN A  91
HIS A  95
ARG A 239
GLU A 242
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
 0.53A 4qyqD-2gjmA:
22.2		 4qyqD-2gjmA:
95.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN)		 3tjq SERINE PROTEASE
HTRA1
(Homo
sapiens) 		5 / 12 ALA A 134
ARG A 137
GLY A  55
ALA A 113
GLY A  86
 SCN  A 163 (-3.3A)
SCN  A 163 ( 4.4A)
SCN  A 163 ( 4.4A)
SCN  A 159 ( 4.6A)
SCN  A 159 ( 3.8A)
 1.28A 4r29C-3tjqA:
undetectable		 4r29C-3tjqA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN)		 3tl2 MALATE DEHYDROGENASE
(Bacillus
anthracis) 		5 / 12 ARG A  87
ALA A  86
GLY A  84
ALA A 129
MET A 130
 None
None
None
SCN  A 314 ( 4.0A)
None
 1.26A 4r29C-3tl2A:
undetectable		 4r29C-3tl2A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5buo AMYLOID BETA A4
PROTEIN
(Homo
sapiens) 		5 / 9 ILE A 451
LEU A 390
VAL A 461
ILE A 462
PHE A 437
 SCN  A 714 ( 3.9A)
None
GOL  A 709 ( 4.9A)
None
None
 1.23A 4r38C-5buoA:
undetectable		 4r38C-5buoA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RDX_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 5ohs -
(-) 		4 / 7 GLU A 580
ARG A 632
GLY A 630
GLY A 615
 None
None
SCN  A 702 ( 4.3A)
SCN  A 702 ( 3.8A)
 0.90A 4rdxA-5ohsA:
undetectable		 4rdxA-5ohsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 GLU B 375
LEU B 256
PHE B 411
TYR B 249
 SCN  B 708 (-3.8A)
None
None
None
 1.04A 4twdF-4l37B:
undetectable
4twdJ-4l37B:
undetectable		 4twdF-4l37B:
16.57
4twdJ-4l37B:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 7 GLU A 372
LEU A 253
PHE A 408
TYR A 246
 SCN  A 709 (-3.8A)
None
None
None
 1.03A 4twdF-4l37A:
undetectable
4twdJ-4l37A:
undetectable		 4twdF-4l37A:
17.24
4twdJ-4l37A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 4a6u OMEGA TRANSAMINASE
(Chromobacterium
violaceum) 		5 / 12 SER A 291
GLY A 293
GLY A 120
GLY A 298
GLY A 289
 None
SCN  A 602 ( 4.8A)
None
None
None
 0.96A 5ekxA-4a6uA:
undetectable		 5ekxA-4a6uA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FF1_A_MMZA601_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 5 GLN A  91
HIS A  95
ARG A 239
GLU A 242
LEU A 246
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
 0.39A 5ff1A-2gjmA:
59.5		 5ff1A-2gjmA:
95.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FF1_A_MMZA602_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 5 GLN A  91
HIS A  95
ARG A 239
GLU A 242
LEU A 246
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
 0.39A 5ff1A-2gjmA:
59.5		 5ff1A-2gjmA:
95.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FF1_B_MMZB601_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 5 GLN A  91
HIS A  95
ARG A 239
GLU A 242
LEU A 246
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
 0.38A 5ff1B-2gjmA:
65.7		 5ff1B-2gjmA:
95.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FF1_B_MMZB613_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 5 GLN A  91
HIS A  95
ARG A 239
GLU A 242
LEU A 246
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
 0.38A 5ff1B-2gjmA:
65.7		 5ff1B-2gjmA:
95.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 2wl1 PYRIN
(Homo
sapiens) 		5 / 12 VAL A 587
LEU A 709
HIS A 739
SER A 728
THR A 707
 None
None
None
None
SCN  A1778 ( 4.7A)
 1.05A 5hnwB-2wl1A:
undetectable		 5hnwB-2wl1A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 2wl1 PYRIN
(Homo
sapiens) 		5 / 12 VAL A 587
LEU A 709
HIS A 739
SER A 728
THR A 707
 None
None
None
None
SCN  A1778 ( 4.7A)
 1.10A 5hnyB-2wl1A:
undetectable		 5hnyB-2wl1A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 2wl1 PYRIN
(Homo
sapiens) 		5 / 12 VAL A 587
LEU A 709
HIS A 739
SER A 728
THR A 707
 None
None
None
None
SCN  A1778 ( 4.7A)
 1.09A 5hnzB-2wl1A:
undetectable		 5hnzB-2wl1A:
17.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HPW_A_3CJA609_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 5 GLN A  91
HIS A  95
ARG A 239
GLU A 242
ARG A 333
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
HEM  A 605 (-2.8A)
 0.43A 5hpwA-2gjmA:
59.2		 5hpwA-2gjmA:
95.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HPW_B_3CJB609_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		4 / 4 GLN A  91
HIS A  95
ARG A 239
ARG A 333
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 (-2.8A)
 0.38A 5hpwB-2gjmA:
59.0		 5hpwB-2gjmA:
95.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPW_B_3CJB609_1
(LACTOPEROXIDASE)		 5k9h 0940_GH29
(unidentified) 		4 / 4 GLN A  18
HIS A 401
ARG A 402
ARG A  68
 None
None
GOL  A 606 (-3.3A)
SCN  A 624 ( 3.6A)
 1.26A 5hpwB-5k9hA:
0.0		 5hpwB-5k9hA:
21.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HPW_C_3CJC609_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		6 / 6 GLN A  91
ASP A  94
HIS A  95
ARG A 239
GLU A 242
ARG A 333
 HEM  A 605 (-3.4A)
HEM  A 605 (-2.0A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
HEM  A 605 (-2.8A)
 0.56A 5hpwC-2gjmA:
27.2		 5hpwC-2gjmA:
95.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HPW_D_3CJD609_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		4 / 4 GLN A  91
HIS A  95
ARG A 239
GLU A 242
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
 0.53A 5hpwD-2gjmA:
22.1		 5hpwD-2gjmA:
95.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)		 4eb0 LCC
(uncultured
bacterium) 		5 / 12 ILE A  89
LEU A 109
GLY A  42
PRO A  43
LEU A 142
 None
None
SCN  A 301 (-3.6A)
None
None
 1.20A 5ienA-4eb0A:
undetectable		 5ienA-4eb0A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		4 / 7 HIS A  95
ILE A  92
VAL A  93
TYR A 296
 SCN  A1502 ( 4.8A)
None
None
None
 1.24A 5kkzM-2gjmA:
undetectable
5kkzO-2gjmA:
undetectable		 5kkzM-2gjmA:
15.16
5kkzO-2gjmA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 PHE B 401
THR B 404
TYR B 402
TYR B 415
 None
None
SCN  B 708 (-4.8A)
None
 1.30A 5lrbA-4l37B:
undetectable		 5lrbA-4l37B:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 6 PHE A 398
THR A 401
TYR A 399
TYR A 412
 None
None
SCN  A 709 (-4.6A)
None
 1.29A 5lrbA-4l37A:
undetectable		 5lrbA-4l37A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5bu6 BPSB (PGAB),
POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE
(Bordetella
bronchiseptica) 		5 / 8 ASP A 113
ASP A 114
HIS A 184
HIS A 189
PRO A 251
 None
NI  A 401 (-2.5A)
NI  A 401 ( 3.3A)
NI  A 401 ( 3.3A)
SCN  A 404 ( 4.7A)
 0.48A 5nekB-5bu6A:
9.3		 5nekB-5bu6A:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		4 / 7 GLY A 335
HIS A 336
HIS A  95
ASP A  94
 HEM  A 605 (-3.4A)
HEM  A 605 (-3.3A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-2.0A)
 1.07A 5nnwD-2gjmA:
undetectable		 5nnwD-2gjmA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_B_SAMB501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 2uye REGULATORY PROTEIN
(Burkholderia
cepacia) 		5 / 9 LEU A 213
ILE A 218
GLY A 217
LEU A 268
ALA A 266
 SCN  A1306 ( 4.9A)
None
None
SCN  A1306 ( 4.5A)
SCN  A1306 ( 4.1A)
 0.93A 5o96A-2uyeA:
undetectable
5o96B-2uyeA:
undetectable		 5o96A-2uyeA:
20.51
5o96B-2uyeA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGC_B_TA1B601_1
(TUBULIN BETA CHAIN)		 2wl1 PYRIN
(Homo
sapiens) 		5 / 12 VAL A 587
LEU A 709
HIS A 739
SER A 728
THR A 707
 None
None
None
None
SCN  A1778 ( 4.7A)
 1.11A 5ogcB-2wl1A:
undetectable		 5ogcB-2wl1A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIH_A_8CVA201_1
(DIHYDROFOLATE
REDUCTASE)		 3pvz UDP-N-ACETYLGLUCOSAM
INE 4,6-DEHYDRATASE
(Aliivibrio
fischeri) 		4 / 8 ILE A 270
ALA A 201
LEU A   5
ILE A 265
 None
SCN  A 604 ( 4.9A)
None
None
 0.71A 5uihA-3pvzA:
undetectable		 5uihA-3pvzA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		3 / 3 TYR A 126
ALA A 217
TYR A 221
 None
SCN  A 711 ( 4.4A)
None
 0.81A 5uunB-4l37A:
undetectable		 5uunB-4l37A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA612_1
(SERUM ALBUMIN)		 5aqa OFF7_DB04V3
(synthetic
construct) 		5 / 12 LEU A 181
LEU A 324
LEU A 320
ALA A 362
GLU A 342
 None
None
None
None
SCN  A1422 (-4.3A)
 1.18A 5v0vA-5aqaA:
undetectable		 5v0vA-5aqaA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 4pcg VP1
(Human
polyomavirus
6) 		4 / 8 ALA A 185
THR A  77
THR A 246
ALA A  40
 SCN  A 301 (-3.5A)
SCN  A 301 ( 4.2A)
None
SCN  A 303 (-4.9A)
 0.95A 5x2tI-4pcgA:
undetectable
5x2tJ-4pcgA:
undetectable
5x2tK-4pcgA:
undetectable
5x2tL-4pcgA:
undetectable		 5x2tI-4pcgA:
19.48
5x2tJ-4pcgA:
20.68
5x2tK-4pcgA:
19.48
5x2tL-4pcgA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6d2v TERB OXIDOREDUCTASE
(Streptomyces) 		3 / 3 TYR A  64
ARG A 100
THR A 103
 None
None
SCN  A 402 ( 4.1A)
 1.03A 5z84J-6d2vA:
undetectable		 5z84J-6d2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_1
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 5dlb CHAPERONE ESPG3
(Mycobacterium
marinum) 		4 / 6 SER A 257
GLU A 215
ARG A  87
ASP A  85
 SCN  A 314 ( 2.9A)
None
None
None
 1.24A 5zw4A-5dlbA:
undetectable		 5zw4A-5dlbA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 3hk0 GROWTH FACTOR
RECEPTOR-BOUND
PROTEIN 10
(Homo
sapiens) 		4 / 8 LEU A 345
TYR A 341
GLU A 170
ASN A 285
 SCN  A  15 ( 4.8A)
None
None
None
 1.09A 6c71B-3hk0A:
undetectable		 6c71B-3hk0A:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_2
(TUBULIN BETA CHAIN)		 5k9h 0940_GH29
(unidentified) 		4 / 5 LEU A 373
THR A 344
ARG A 403
ARG A 356
 None
None
None
SCN  A 626 (-3.2A)
 1.20A 6ew0B-5k9hA:
undetectable		 6ew0B-5k9hA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_2
(TUBULIN BETA CHAIN)		 5k9h 0940_GH29
(unidentified) 		4 / 5 LEU A 373
THR A 344
ARG A 403
ARG A 356
 None
None
None
SCN  A 626 (-3.2A)
 1.20A 6ew0D-5k9hA:
undetectable		 6ew0D-5k9hA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_2
(TUBULIN BETA CHAIN)		 5k9h 0940_GH29
(unidentified) 		4 / 5 LEU A 373
THR A 344
ARG A 403
ARG A 356
 None
None
None
SCN  A 626 (-3.2A)
 1.20A 6ew0H-5k9hA:
undetectable		 6ew0H-5k9hA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_2
(TUBULIN BETA CHAIN)		 5k9h 0940_GH29
(unidentified) 		4 / 5 LEU A 373
THR A 344
ARG A 403
ARG A 356
 None
None
None
SCN  A 626 (-3.2A)
 1.20A 6ew0I-5k9hA:
undetectable		 6ew0I-5k9hA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 4a6u OMEGA TRANSAMINASE
(Chromobacterium
violaceum) 		4 / 7 GLY A 293
TYR A 294
GLU A  40
GLY A  67
 SCN  A 602 ( 4.8A)
None
None
SCN  A 601 (-3.5A)
 0.88A 6n7fA-4a6uA:
undetectable		 6n7fA-4a6uA:
10.96