SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'SB9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HMY_B_SAMB328_0 (PROTEIN (CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI))	2aie	PEPTIDE DEFORMYLASE (Streptococcus pneumoniae)	5 / 12	GLY P 69 ASP P 14 ILE P 13 TYR P 166 VAL P 170	SB9 P 501 ( 4.9A) None None SB9 P 501 (-4.5A) SB9 P 501 ( 4.1A)	0.96A	2hmyB-2aieP: undetectable	2hmyB-2aieP: 21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD5_A_CHDA701_0 (FERROCHELATASE)	2aie	PEPTIDE DEFORMYLASE (Streptococcus pneumoniae)	4 / 8	LEU P 123 PRO P 89 VAL P 86 GLY P 71	None None None SB9 P 501 (-4.4A)	1.10A	2qd5A-2aieP: undetectable	2qd5A-2aieP: 17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KEC_B_HAEB271_1 (COLLAGENASE 3)	2aie	PEPTIDE DEFORMYLASE (Streptococcus pneumoniae)	3 / 3	HIS P 173 GLU P 174 HIS P 177	NI P 502 ( 3.4A) SB9 P 501 (-2.7A) NI P 502 ( 3.3A)	0.18A	3kecB-2aieP: undetectable	3kecB-2aieP: 20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7B_B_HAEB1270_1 (COLLAGENASE 3)	2aie	PEPTIDE DEFORMYLASE (Streptococcus pneumoniae)	4 / 5	LEU P 52 HIS P 173 GLU P 174 HIS P 177	None NI P 502 ( 3.4A) SB9 P 501 (-2.7A) NI P 502 ( 3.3A)	0.90A	4a7bB-2aieP: undetectable	4a7bB-2aieP: 20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NWV_A_ACAA18_2 (SCRFP-TAG,GP41)	2aie	PEPTIDE DEFORMYLASE (Streptococcus pneumoniae)	4 / 7	GLN P 76 LEU P 72 ALA P 106 LEU P 104	SB9 P 501 ( 2.7A) None None None	1.05A	5nwvA-2aieP: undetectable	5nwvA-2aieP: 17.12

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2HMY_B_SAMB328_0","PROTEIN (CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI)","2aie","PEPTIDE DEFORMYLASE","Streptococcus pneumoniae",5,"GLY P  69;ASP P  14;ILE P  13;TYR P 166;VAL P 170","SB9 P 501 ( 4.9A);None;None;SB9 P 501 (-4.5A);SB9 P 501 ( 4.1A)","0.96A","2hmyB-2aieP:undetectable",null],["2QD5_A_CHDA701_0","FERROCHELATASE","2aie","PEPTIDE DEFORMYLASE","Streptococcus pneumoniae",4,"LEU P 123;PRO P  89;VAL P  86;GLY P  71","None;None;None;SB9 P 501 (-4.4A)","1.10A","2qd5A-2aieP:undetectable","2hmyB-2aieP:21.34"],["3KEC_B_HAEB271_1","COLLAGENASE 3","2aie","PEPTIDE DEFORMYLASE","Streptococcus pneumoniae",3,"HIS P 173;GLU P 174;HIS P 177"," NI P 502 ( 3.4A);SB9 P 501 (-2.7A); NI P 502 ( 3.3A)","0.18A","3kecB-2aieP:undetectable","2qd5A-2aieP:17.09"],["4A7B_B_HAEB1270_1","COLLAGENASE 3","2aie","PEPTIDE DEFORMYLASE","Streptococcus pneumoniae",4,"LEU P  52;HIS P 173;GLU P 174;HIS P 177","None; NI P 502 ( 3.4A);SB9 P 501 (-2.7A); NI P 502 ( 3.3A)","0.90A","4a7bB-2aieP:undetectable","3kecB-2aieP:20.72"],["5NWV_A_ACAA18_2","SCRFP-TAG,GP41","2aie","PEPTIDE DEFORMYLASE","Streptococcus pneumoniae",4,"GLN P  76;LEU P  72;ALA P 106;LEU P 104","SB9 P 501 ( 2.7A);None;None;None","1.05A","5nwvA-2aieP:undetectable","4a7bB-2aieP:20.70"]]