SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'SAZ'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 6 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.96A 1dz4A-1yyrA:
undetectable		 1dz4A-1yyrA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 6 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.88A 1dz4B-1yyrA:
undetectable		 1dz4B-1yyrA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 8 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.92A 1dz9A-1yyrA:
0.1		 1dz9A-1yyrA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 8 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.89A 1iwiA-1yyrA:
undetectable		 1iwiA-1yyrA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 8 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.85A 1o76B-1yyrA:
undetectable		 1o76B-1yyrA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 7 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.98A 1t85A-1yyrA:
0.0		 1t85A-1yyrA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 8 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.92A 1t86A-1yyrA:
undetectable		 1t86A-1yyrA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 7 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.88A 1t87A-1yyrA:
undetectable		 1t87A-1yyrA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 7 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.91A 1t87B-1yyrA:
undetectable		 1t87B-1yyrA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 7 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.91A 1t88A-1yyrA:
undetectable		 1t88A-1yyrA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 5 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.94A 1t88B-1yyrA:
undetectable		 1t88B-1yyrA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 8 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.94A 1uyuA-1yyrA:
undetectable		 1uyuA-1yyrA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 8 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.87A 1uyuB-1yyrA:
undetectable		 1uyuB-1yyrA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 7 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.93A 1yrcA-1yyrA:
0.0		 1yrcA-1yyrA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 7 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.91A 1yrdA-1yyrA:
undetectable		 1yrdA-1yyrA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 7 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.93A 2cppA-1yyrA:
undetectable		 2cppA-1yyrA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 6 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.99A 2feuA-1yyrA:
0.0		 2feuA-1yyrA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 7 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.96A 2feuB-1yyrA:
0.0		 2feuB-1yyrA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 5 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.94A 2m56A-1yyrA:
undetectable		 2m56A-1yyrA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 7 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.85A 2qblA-1yyrA:
undetectable		 2qblA-1yyrA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 6 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.92A 2z97A-1yyrA:
undetectable		 2z97A-1yyrA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 6 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.84A 2zawA-1yyrA:
0.0		 2zawA-1yyrA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 7 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.92A 2zaxA-1yyrA:
undetectable		 2zaxA-1yyrA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 6 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.89A 2zuhA-1yyrA:
0.2		 2zuhA-1yyrA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 6 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.91A 2zuiA-1yyrA:
undetectable		 2zuiA-1yyrA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 7 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.92A 2zwtA-1yyrA:
undetectable		 2zwtA-1yyrA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 7 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.92A 2zwuA-1yyrA:
undetectable		 2zwuA-1yyrA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 7 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.98A 3fwfA-1yyrA:
0.0		 3fwfA-1yyrA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 7 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 1.00A 3fwfB-1yyrA:
0.0		 3fwfB-1yyrA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 6 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.98A 3fwgA-1yyrA:
undetectable		 3fwgA-1yyrA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 7 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.94A 3fwgB-1yyrA:
undetectable		 3fwgB-1yyrA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 7 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.93A 3fwiA-1yyrA:
undetectable		 3fwiA-1yyrA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 7 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.95A 3fwjA-1yyrA:
0.0		 3fwjA-1yyrA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		5 / 9 TYR A 295
PHE A 291
GLY A 188
THR A  96
ILE A  70
 None
None
None
SAZ  A 709 (-3.9A)
None
 1.41A 3jusB-1yyrA:
undetectable		 3jusB-1yyrA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 7 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 1.01A 3l63A-1yyrA:
3.7		 3l63A-1yyrA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 7 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.94A 3wrhA-1yyrA:
0.1		 3wrhA-1yyrA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 6 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.95A 3wrhE-1yyrA:
undetectable		 3wrhE-1yyrA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 7 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.95A 3wrjA-1yyrA:
0.1		 3wrjA-1yyrA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 6 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.97A 3wrjE-1yyrA:
undetectable		 3wrjE-1yyrA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 7 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.94A 3wrlA-1yyrA:
0.1		 3wrlA-1yyrA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 7 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.99A 3wrlE-1yyrA:
undetectable		 3wrlE-1yyrA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 7 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.97A 3wrmA-1yyrA:
undetectable		 3wrmA-1yyrA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 7 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.97A 3wrmF-1yyrA:
0.1		 3wrmF-1yyrA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 6 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 1.05A 4ek1A-1yyrA:
undetectable		 4ek1A-1yyrA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 6 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.99A 4g3rA-1yyrA:
undetectable		 4g3rA-1yyrA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 6 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.98A 4g3rB-1yyrA:
undetectable		 4g3rB-1yyrA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 6 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.98A 4kkyX-1yyrA:
0.0		 4kkyX-1yyrA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 5 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.97A 4l49A-1yyrA:
undetectable		 4l49A-1yyrA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 8 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.92A 4l4aA-1yyrA:
undetectable		 4l4aA-1yyrA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 8 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.94A 4l4bA-1yyrA:
undetectable		 4l4bA-1yyrA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 6 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 1.04A 4l4cA-1yyrA:
undetectable		 4l4cA-1yyrA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 8 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.93A 4l4dA-1yyrA:
undetectable		 4l4dA-1yyrA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 7 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.92A 4l4gA-1yyrA:
undetectable		 4l4gA-1yyrA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		5 / 12 GLY A 188
GLY A 186
THR A  96
ARG A 182
ILE A 214
 None
SAZ  A 709 (-3.8A)
SAZ  A 709 (-3.9A)
SAZ  A 709 ( 3.8A)
None
 1.07A 5bw4A-1yyrA:
undetectable		 5bw4A-1yyrA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA617_0
(SERUM ALBUMIN)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		3 / 3 TRP A 298
ARG A 304
LEU A 307
 None
SAZ  A 709 ( 4.5A)
None
 0.96A 5dbyA-1yyrA:
0.0		 5dbyA-1yyrA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZ2_A_212A404_1
(GERMACRADIENOL/GEOSM
IN SYNTHASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		5 / 9 ARG A 182
ASN A 225
SER A 229
GLU A 233
ARG A 304
 SAZ  A 709 ( 3.8A)
SAZ  A 709 (-3.3A)
None
None
SAZ  A 709 ( 4.5A)
 0.99A 5dz2A-1yyrA:
19.9		 5dz2A-1yyrA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZ2_B_212B404_1
(GERMACRADIENOL/GEOSM
IN SYNTHASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		5 / 9 ARG A 182
ASN A 225
SER A 229
GLU A 233
ARG A 304
 SAZ  A 709 ( 3.8A)
SAZ  A 709 (-3.3A)
None
None
SAZ  A 709 ( 4.5A)
 1.03A 5dz2B-1yyrA:
20.1		 5dz2B-1yyrA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERM_A_210A401_1
(FUSICOCCADIENE
SYNTHASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		5 / 10 ARG A 182
ASN A 225
SER A 229
LYS A 232
ARG A 304
 SAZ  A 709 ( 3.8A)
SAZ  A 709 (-3.3A)
None
None
SAZ  A 709 ( 4.5A)
 0.84A 5ermA-1yyrA:
6.4		 5ermA-1yyrA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERM_A_210A401_1
(FUSICOCCADIENE
SYNTHASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		5 / 10 ASN A 225
SER A 229
LYS A 232
GLU A 233
ARG A 304
 SAZ  A 709 (-3.3A)
None
None
None
SAZ  A 709 ( 4.5A)
 0.79A 5ermA-1yyrA:
6.4		 5ermA-1yyrA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERM_A_210A401_1
(FUSICOCCADIENE
SYNTHASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		5 / 10 ASP A 239
ARG A 182
ASN A 225
SER A 229
LYS A 232
 None
SAZ  A 709 ( 3.8A)
SAZ  A 709 (-3.3A)
None
None
 1.21A 5ermA-1yyrA:
6.4		 5ermA-1yyrA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERM_B_210B704_1
(FUSICOCCADIENE
SYNTHASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		5 / 9 ASN A 225
SER A 229
LYS A 232
GLU A 233
ARG A 304
 SAZ  A 709 (-3.3A)
None
None
None
SAZ  A 709 ( 4.5A)
 0.72A 5ermB-1yyrA:
6.1		 5ermB-1yyrA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		5 / 12 ASP A 226
HIS A 299
PHE A 291
ARG A 182
GLY A 186
 None
None
None
SAZ  A 709 ( 3.8A)
SAZ  A 709 (-3.8A)
 1.29A 5m54E-1yyrA:
undetectable		 5m54E-1yyrA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1yyr TRICHODIENE SYNTHASE
(Fusarium
sporotrichioides) 		4 / 7 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 1.02A 5wk9A-1yyrA:
0.2		 5wk9A-1yyrA:
22.83