SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'SA0'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDT_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis) 		5 / 11 LEU A 189
HIS A 148
SER A 105
PHE A 104
GLU A 402
 None
SA0  A 507 (-4.0A)
None
None
SA0  A 507 (-2.4A)
 1.39A 1fdtA-3vilA:
undetectable		 1fdtA-3vilA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis) 		4 / 6 ILE A 400
ASN A 335
ASN A 192
THR A 145
 None
SA0  A 507 ( 4.9A)
SA0  A 507 (-3.4A)
None
 1.24A 1h7xA-3vilA:
6.4		 1h7xA-3vilA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis) 		4 / 6 ILE A 400
ASN A 335
SER A 251
ASN A 192
 None
SA0  A 507 ( 4.9A)
None
SA0  A 507 (-3.4A)
 1.24A 1h7xA-3vilA:
6.4		 1h7xA-3vilA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_B_URFB1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis) 		5 / 6 ILE A 400
ASN A 335
SER A 251
ASN A 192
THR A 145
 None
SA0  A 507 ( 4.9A)
None
SA0  A 507 (-3.4A)
None
 1.44A 1h7xB-3vilA:
6.4		 1h7xB-3vilA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis) 		4 / 6 ILE A 400
ASN A 335
ASN A 192
THR A 145
 None
SA0  A 507 ( 4.9A)
SA0  A 507 (-3.4A)
None
 1.24A 1h7xC-3vilA:
6.3		 1h7xC-3vilA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis) 		4 / 6 ILE A 400
ASN A 335
SER A 251
ASN A 192
 None
SA0  A 507 ( 4.9A)
None
SA0  A 507 (-3.4A)
 1.24A 1h7xC-3vilA:
6.3		 1h7xC-3vilA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis) 		4 / 6 ILE A 400
ASN A 335
ASN A 192
THR A 145
 None
SA0  A 507 ( 4.9A)
SA0  A 507 (-3.4A)
None
 1.24A 1h7xD-3vilA:
8.3		 1h7xD-3vilA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis) 		4 / 6 ILE A 400
ASN A 335
SER A 251
ASN A 192
 None
SA0  A 507 ( 4.9A)
None
SA0  A 507 (-3.4A)
 1.22A 1h7xD-3vilA:
8.3		 1h7xD-3vilA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis) 		3 / 3 ASP A 150
TRP A 444
SER A 105
 None
SA0  A 507 (-3.7A)
None
 1.02A 4lrhB-3vilA:
undetectable		 4lrhB-3vilA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis) 		3 / 3 ASP A 150
TRP A 444
SER A 105
 None
SA0  A 507 (-3.7A)
None
 1.10A 4lrhF-3vilA:
undetectable		 4lrhF-3vilA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PHH_A_LDPA414_1
(LYSINE-SPECIFIC
DEMETHYLASE 4D)		 3vil BETA-GLUCOSIDASE
(Neotermes
koshunensis) 		4 / 6 GLU A 402
ARG A 103
TYR A 337
SER A 193
 SA0  A 507 (-2.4A)
None
SA0  A 507 (-4.1A)
SA0  A 507 (-3.5A)
 1.00A 5phhA-3vilA:
undetectable		 5phhA-3vilA:
22.22