SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'S55'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_A_EPAA1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2v91 STRICTOSIDINE
SYNTHASE
(Rauvolfia
serpentina) 		6 / 12 VAL A 248
VAL A 266
SER A 268
GLY A 210
ALA A 224
LEU A 222
 None
None
None
S55  A1334 (-3.5A)
None
None
 1.32A 3hs6A-2v91A:
undetectable		 3hs6A-2v91A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 2v91 STRICTOSIDINE
SYNTHASE
(Rauvolfia
serpentina) 		3 / 3 HIS A 277
SER A 269
GLU A 271
 S55  A1334 (-4.2A)
S55  A1334 ( 3.7A)
None
 0.92A 3s8pA-2v91A:
undetectable		 3s8pA-2v91A:
22.26