SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'S2N'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 3i3a ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Leptospira
interrogans) 		4 / 7 SER A  49
PHE A  88
ILE A  45
GLY A 119
 None
None
None
S2N  A 260 ( 3.8A)
 1.02A 2v0mC-3i3aA:
undetectable		 2v0mC-3i3aA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 3i3a ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Leptospira
interrogans) 		5 / 12 ILE A 106
GLY A 138
GLY A 119
LEU A 130
GLY A  97
 None
S2N  A 260 (-3.8A)
S2N  A 260 ( 3.8A)
None
None
 1.01A 3uq6A-3i3aA:
undetectable		 3uq6A-3i3aA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 3i3a ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Leptospira
interrogans) 		5 / 12 ILE A 106
GLY A 138
GLY A 119
LEU A 130
GLY A  97
 None
S2N  A 260 (-3.8A)
S2N  A 260 ( 3.8A)
None
None
 1.01A 3vasA-3i3aA:
undetectable		 3vasA-3i3aA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 3i3a ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Leptospira
interrogans) 		4 / 7 THR A 104
GLY A  97
THR A  80
HIS A 117
 None
None
None
S2N  A 260 (-3.9A)
 0.92A 4qwpB-3i3aA:
undetectable		 4qwpB-3i3aA:
23.15