SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'S1H'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CML_C_ZMRC3478_1 (NEURAMINIDASE)	1fw3	OUTER MEMBRANE PHOSPHOLIPASE A (Escherichia coli)	4 / 8	SER A 248 ASP A 251 ASN A 113 GLN A 94	None None S1H A 144 ( 4.2A) None	1.11A	2cmlC-1fw3A: undetectable	2cmlC-1fw3A: 20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VYW_A_SAMA501_1 (MNMC2)	1fw3	OUTER MEMBRANE PHOSPHOLIPASE A (Escherichia coli)	4 / 6	ASP A 251 ASP A 149 ASN A 145 GLU A 111	None None S1H A 144 ( 4.9A) None	1.20A	3vywA-1fw3A: undetectable	3vywA-1fw3A: 20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VYW_D_SAMD401_1 (MNMC2)	1fw3	OUTER MEMBRANE PHOSPHOLIPASE A (Escherichia coli)	4 / 5	ASP A 251 ASP A 149 ASN A 145 GLU A 111	None None S1H A 144 ( 4.9A) None	1.11A	3vywD-1fw3A: undetectable	3vywD-1fw3A: 20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AWU_A_4CHA502_0 (OXIDOREDUCTASE, FMN-BINDING)	1fw3	OUTER MEMBRANE PHOSPHOLIPASE A (Escherichia coli)	4 / 7	THR A 112 TYR A 92 LEU A 71 PHE A 109	None S1H A 144 ( 3.8A) None None	1.07A	4awuA-1fw3A: undetectable	4awuA-1fw3A: 23.77

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2CML_C_ZMRC3478_1","NEURAMINIDASE","1fw3","OUTER MEMBRANE PHOSPHOLIPASE A","Escherichia coli",4,"SER A 248;ASP A 251;ASN A 113;GLN A  94","None;None;S1H A 144 ( 4.2A);None","1.11A","2cmlC-1fw3A:undetectable",null],["3VYW_A_SAMA501_1","MNMC2","1fw3","OUTER MEMBRANE PHOSPHOLIPASE A","Escherichia coli",4,"ASP A 251;ASP A 149;ASN A 145;GLU A 111","None;None;S1H A 144 ( 4.9A);None","1.20A","3vywA-1fw3A:undetectable","2cmlC-1fw3A:20.10"],["3VYW_D_SAMD401_1","MNMC2","1fw3","OUTER MEMBRANE PHOSPHOLIPASE A","Escherichia coli",4,"ASP A 251;ASP A 149;ASN A 145;GLU A 111","None;None;S1H A 144 ( 4.9A);None","1.11A","3vywD-1fw3A:undetectable","3vywA-1fw3A:20.57"],["4AWU_A_4CHA502_0","OXIDOREDUCTASE, FMN-BINDING","1fw3","OUTER MEMBRANE PHOSPHOLIPASE A","Escherichia coli",4,"THR A 112;TYR A  92;LEU A  71;PHE A 109","None;S1H A 144 ( 3.8A);None;None","1.07A","4awuA-1fw3A:undetectable","3vywD-1fw3A:20.57"]]