SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'RUJ'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 4bhi GAMMA-BUTYROBETAINE
DIOXYGENASE
(Homo
sapiens) 		5 / 12 HIS A 202
ASP A 261
ALA A 193
HIS A 347
ASP A 204
 ZN  A 402 ( 3.3A)
RUJ  A 401 ( 4.7A)
OGA  A 400 (-3.1A)
ZN  A 402 ( 3.3A)
ZN  A 402 (-2.6A)
 1.26A 1a4lA-4bhiA:
undetectable		 1a4lA-4bhiA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 4bhi GAMMA-BUTYROBETAINE
DIOXYGENASE
(Homo
sapiens) 		5 / 12 HIS A 202
ASP A 261
ALA A 193
HIS A 347
ASP A 204
 ZN  A 402 ( 3.3A)
RUJ  A 401 ( 4.7A)
OGA  A 400 (-3.1A)
ZN  A 402 ( 3.3A)
ZN  A 402 (-2.6A)
 1.25A 1a4lC-4bhiA:
undetectable		 1a4lC-4bhiA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 4bhi GAMMA-BUTYROBETAINE
DIOXYGENASE
(Homo
sapiens) 		3 / 3 ASN A 190
ASP A 261
ASP A 204
 None
RUJ  A 401 ( 4.7A)
ZN  A 402 (-2.6A)
 0.75A 4obwD-4bhiA:
undetectable		 4obwD-4bhiA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 4bhi GAMMA-BUTYROBETAINE
DIOXYGENASE
(Homo
sapiens) 		5 / 12 ILE A 358
TYR A 194
GLN A 215
LEU A 217
LEU A 362
 None
RUJ  A 401 (-4.3A)
ZN  A 402 ( 4.2A)
None
OGA  A 400 (-4.9A)
 1.43A 4qztA-4bhiA:
undetectable		 4qztA-4bhiA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_C7HA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4bhi GAMMA-BUTYROBETAINE
DIOXYGENASE
(Homo
sapiens) 		4 / 5 GLY A 263
TYR A 205
TYR A 177
GLY A 178
 None
RUJ  A 401 (-4.1A)
RUJ  A 401 (-3.8A)
None
 0.94A 5ayfA-4bhiA:
undetectable		 5ayfA-4bhiA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC0_A_RBFA303_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 4bhi GAMMA-BUTYROBETAINE
DIOXYGENASE
(Homo
sapiens) 		5 / 12 GLU A 230
LEU A 199
ALA A 294
ASN A 292
PHE A 291
 None
OGA  A 400 (-4.8A)
None
RUJ  A 401 (-4.1A)
None
 1.43A 5kc0A-4bhiA:
undetectable		 5kc0A-4bhiA:
19.01