SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'RTL'


List of Similar Pattern of Amino Acids


Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AQB_A_RTLA185_0
(RETINOL-BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
10 / 10 LEU A  35
ALA A  55
VAL A  61
MET A  73
MET A  88
TYR A  90
LEU A  97
GLN A  98
HIS A 104
PHE A 135
RTL  A 176 (-4.5A)
RTL  A 176 ( 3.8A)
None
RTL  A 176 ( 4.0A)
RTL  A 176 (-3.4A)
RTL  A 176 ( 4.0A)
RTL  A 176 (-4.0A)
RTL  A 176 (-3.8A)
RTL  A 176 ( 4.7A)
RTL  A 176 ( 4.2A)
0.36A 1aqbA-1iiuA:
32.8
1aqbA-1iiuA:
80.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BRP_A_RTLA183_0
(RETINOL BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
5 / 12 ALA A  43
PHE A  77
MET A  88
HIS A 104
PHE A 135
RTL  A 176 ( 4.1A)
None
RTL  A 176 (-3.4A)
RTL  A 176 ( 4.7A)
RTL  A 176 ( 4.2A)
1.00A 1brpA-1iiuA:
31.3
1brpA-1iiuA:
84.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BRP_A_RTLA183_0
(RETINOL BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
5 / 12 ALA A  57
GLY A  75
PHE A  77
MET A  88
PHE A 137
RTL  A 176 ( 3.8A)
RTL  A 176 ( 4.0A)
None
RTL  A 176 (-3.4A)
None
1.16A 1brpA-1iiuA:
31.3
1brpA-1iiuA:
84.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BRP_A_RTLA183_0
(RETINOL BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
6 / 12 LEU A  37
ALA A  57
MET A  73
LEU A  97
GLN A  98
HIS A 117
RTL  A 176 ( 4.5A)
RTL  A 176 ( 3.8A)
RTL  A 176 ( 4.0A)
RTL  A 176 (-4.0A)
RTL  A 176 (-3.8A)
RTL  A 176 ( 4.6A)
1.33A 1brpA-1iiuA:
31.3
1brpA-1iiuA:
84.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BRP_A_RTLA183_0
(RETINOL BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
5 / 12 LEU A  37
MET A  73
PHE A  45
LEU A  97
PHE A 135
RTL  A 176 ( 4.5A)
RTL  A 176 ( 4.0A)
RTL  A 176 ( 4.8A)
RTL  A 176 (-4.0A)
RTL  A 176 ( 4.2A)
1.20A 1brpA-1iiuA:
31.3
1brpA-1iiuA:
84.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BRP_A_RTLA183_0
(RETINOL BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
12 / 12 LEU A  37
PHE A  45
ALA A  57
MET A  73
GLY A  75
PHE A  77
MET A  88
TYR A  90
LEU A  97
GLN A  98
HIS A 104
PHE A 135
RTL  A 176 ( 4.5A)
RTL  A 176 ( 4.8A)
RTL  A 176 ( 3.8A)
RTL  A 176 ( 4.0A)
RTL  A 176 ( 4.0A)
None
RTL  A 176 (-3.4A)
RTL  A 176 ( 4.0A)
RTL  A 176 (-4.0A)
RTL  A 176 (-3.8A)
RTL  A 176 ( 4.7A)
RTL  A 176 ( 4.2A)
0.33A 1brpA-1iiuA:
31.3
1brpA-1iiuA:
84.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CRB_A_RTLA200_0
(CELLULAR RETINOL
BINDING PROTEIN)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
8 / 12 PHE A  16
ALA A  33
LEU A  36
ILE A  51
THR A  53
ARG A  58
MET A  62
ILE A  77
RTL  A 135 ( 4.6A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.3A)
None
RTL  A 135 (-2.9A)
RTL  A 135 (-3.5A)
1.01A 1crbA-1mx8A:
20.4
1crbA-1mx8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CRB_A_RTLA200_0
(CELLULAR RETINOL
BINDING PROTEIN)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
8 / 12 PHE A  16
ALA A  33
LEU A  36
LYS A  40
ILE A  51
ARG A  58
MET A  62
ILE A  77
RTL  A 135 ( 4.6A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.4A)
RTL  A 135 ( 4.6A)
None
RTL  A 135 (-2.9A)
RTL  A 135 (-3.5A)
0.95A 1crbA-1mx8A:
20.4
1crbA-1mx8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CRB_A_RTLA200_0
(CELLULAR RETINOL
BINDING PROTEIN)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
7 / 12 PHE A  16
LEU A  20
LEU A  29
ALA A  33
LEU A  36
LYS A  40
ILE A  51
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.7A)
RTL  A 135 (-3.8A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.4A)
RTL  A 135 ( 4.6A)
0.78A 1crbA-1mx8A:
20.4
1crbA-1mx8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CRB_A_RTLA200_0
(CELLULAR RETINOL
BINDING PROTEIN)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
8 / 12 PHE A  16
LEU A  29
ALA A  33
LEU A  36
ILE A  51
THR A  53
MET A  62
ILE A  77
RTL  A 135 ( 4.6A)
RTL  A 135 (-3.8A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.3A)
RTL  A 135 (-2.9A)
RTL  A 135 (-3.5A)
0.95A 1crbA-1mx8A:
20.4
1crbA-1mx8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CRB_A_RTLA200_0
(CELLULAR RETINOL
BINDING PROTEIN)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
8 / 12 PHE A  16
LEU A  29
ALA A  33
LEU A  36
LYS A  40
ILE A  51
MET A  62
ILE A  77
RTL  A 135 ( 4.6A)
RTL  A 135 (-3.8A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.4A)
RTL  A 135 ( 4.6A)
RTL  A 135 (-2.9A)
RTL  A 135 (-3.5A)
0.92A 1crbA-1mx8A:
20.4
1crbA-1mx8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FEM_A_REAA184_1
(RETINOL BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
5 / 10 VAL A  61
MET A  73
LEU A  97
GLN A  98
HIS A 117
None
RTL  A 176 ( 4.0A)
RTL  A 176 (-4.0A)
RTL  A 176 (-3.8A)
RTL  A 176 ( 4.6A)
1.38A 1femA-1iiuA:
22.7
1femA-1iiuA:
79.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FEM_A_REAA184_1
(RETINOL BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
9 / 10 VAL A  61
MET A  73
PHE A  77
MET A  88
TYR A  90
LEU A  97
GLN A  98
HIS A 104
TYR A 133
None
RTL  A 176 ( 4.0A)
None
RTL  A 176 (-3.4A)
RTL  A 176 ( 4.0A)
RTL  A 176 (-4.0A)
RTL  A 176 (-3.8A)
RTL  A 176 ( 4.7A)
None
0.50A 1femA-1iiuA:
22.7
1femA-1iiuA:
79.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FMJ_A_RTLA401_0
(RETINOL DEHYDRATASE)
1fml RETINOL DEHYDRATASE
(Spodoptera
frugiperda)
6 / 11 LEU A 139
SER A 142
LYS A 162
MET A 295
ILE A 301
PHE A 310
None
RTL  A 401 (-3.2A)
RTL  A 401 (-2.6A)
RTL  A 401 ( 4.0A)
None
RTL  A 401 (-4.3A)
1.48A 1fmjA-1fmlA:
56.6
1fmjA-1fmlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FMJ_A_RTLA401_0
(RETINOL DEHYDRATASE)
1fml RETINOL DEHYDRATASE
(Spodoptera
frugiperda)
11 / 11 TYR A 105
TYR A 112
TYR A 120
LEU A 139
SER A 142
LYS A 162
HIS A 164
HIS A 197
MET A 295
ILE A 303
PHE A 310
RTL  A 401 (-4.6A)
RTL  A 401 ( 4.8A)
RTL  A 401 ( 4.5A)
None
RTL  A 401 (-3.2A)
RTL  A 401 (-2.6A)
RTL  A 401 (-4.4A)
RTL  A 401 (-4.2A)
RTL  A 401 ( 4.0A)
RTL  A 401 ( 4.0A)
RTL  A 401 (-4.3A)
0.25A 1fmjA-1fmlA:
56.6
1fmjA-1fmlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FMJ_B_RTLB501_0
(RETINOL DEHYDRATASE)
1fml RETINOL DEHYDRATASE
(Spodoptera
frugiperda)
10 / 10 TYR A 105
TYR A 112
TYR A 120
LEU A 139
SER A 142
LYS A 162
HIS A 164
HIS A 197
MET A 295
ILE A 303
RTL  A 401 (-4.6A)
RTL  A 401 ( 4.8A)
RTL  A 401 ( 4.5A)
None
RTL  A 401 (-3.2A)
RTL  A 401 (-2.6A)
RTL  A 401 (-4.4A)
RTL  A 401 (-4.2A)
RTL  A 401 ( 4.0A)
RTL  A 401 ( 4.0A)
0.29A 1fmjB-1fmlA:
56.9
1fmjB-1fmlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FML_A_RTLA401_0
(RETINOL DEHYDRATASE)
1fml RETINOL DEHYDRATASE
(Spodoptera
frugiperda)
6 / 12 LEU A 138
LEU A 139
SER A 142
TYR A 298
ILE A 301
PHE A 310
RTL  A 401 ( 4.6A)
None
RTL  A 401 (-3.2A)
RTL  A 401 (-4.2A)
None
RTL  A 401 (-4.3A)
1.33A 1fmlA-1fmlA:
60.1
1fmlA-1fmlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FML_A_RTLA401_0
(RETINOL DEHYDRATASE)
1fml RETINOL DEHYDRATASE
(Spodoptera
frugiperda)
12 / 12 TYR A 105
TYR A 112
TYR A 120
LEU A 138
LEU A 139
SER A 142
HIS A 164
HIS A 197
LEU A 201
TYR A 298
ILE A 303
PHE A 310
RTL  A 401 (-4.6A)
RTL  A 401 ( 4.8A)
RTL  A 401 ( 4.5A)
RTL  A 401 ( 4.6A)
None
RTL  A 401 (-3.2A)
RTL  A 401 (-4.4A)
RTL  A 401 (-4.2A)
RTL  A 401 ( 4.3A)
RTL  A 401 (-4.2A)
RTL  A 401 ( 4.0A)
RTL  A 401 (-4.3A)
0.00A 1fmlA-1fmlA:
60.1
1fmlA-1fmlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FML_B_RTLB501_0
(RETINOL DEHYDRATASE)
1fml RETINOL DEHYDRATASE
(Spodoptera
frugiperda)
12 / 12 ILE A 111
TYR A 112
TYR A 120
LEU A 138
LEU A 139
SER A 142
HIS A 164
HIS A 197
LEU A 201
TYR A 298
ILE A 303
PHE A 310
RTL  A 401 ( 4.9A)
RTL  A 401 ( 4.8A)
RTL  A 401 ( 4.5A)
RTL  A 401 ( 4.6A)
None
RTL  A 401 (-3.2A)
RTL  A 401 (-4.4A)
RTL  A 401 (-4.2A)
RTL  A 401 ( 4.3A)
RTL  A 401 (-4.2A)
RTL  A 401 ( 4.0A)
RTL  A 401 (-4.3A)
0.04A 1fmlB-1fmlA:
59.2
1fmlB-1fmlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FML_B_RTLB501_0
(RETINOL DEHYDRATASE)
1fml RETINOL DEHYDRATASE
(Spodoptera
frugiperda)
6 / 12 LEU A 138
LEU A 139
SER A 142
TYR A 298
ILE A 301
PHE A 310
RTL  A 401 ( 4.6A)
None
RTL  A 401 (-3.2A)
RTL  A 401 (-4.2A)
None
RTL  A 401 (-4.3A)
1.34A 1fmlB-1fmlA:
59.2
1fmlB-1fmlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HBP_A_RTLA184_0
(RETINOL BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
6 / 11 ALA A  57
VAL A  61
MET A  73
LEU A  97
GLN A  98
HIS A 117
RTL  A 176 ( 3.8A)
None
RTL  A 176 ( 4.0A)
RTL  A 176 (-4.0A)
RTL  A 176 (-3.8A)
RTL  A 176 ( 4.6A)
1.32A 1hbpA-1iiuA:
32.2
1hbpA-1iiuA:
79.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HBP_A_RTLA184_0
(RETINOL BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
11 / 11 LEU A  35
PHE A  45
ALA A  55
ALA A  57
VAL A  61
MET A  73
MET A  88
TYR A  90
LEU A  97
GLN A  98
HIS A 104
RTL  A 176 (-4.5A)
RTL  A 176 ( 4.8A)
RTL  A 176 ( 3.8A)
RTL  A 176 ( 3.8A)
None
RTL  A 176 ( 4.0A)
RTL  A 176 (-3.4A)
RTL  A 176 ( 4.0A)
RTL  A 176 (-4.0A)
RTL  A 176 (-3.8A)
RTL  A 176 ( 4.7A)
0.37A 1hbpA-1iiuA:
32.2
1hbpA-1iiuA:
79.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IIU_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
11 / 11 LEU A  35
LEU A  37
ALA A  55
ALA A  57
MET A  73
MET A  88
TYR A  90
LEU A  97
GLN A  98
HIS A 104
ARG A 121
RTL  A 176 (-4.5A)
RTL  A 176 ( 4.5A)
RTL  A 176 ( 3.8A)
RTL  A 176 ( 3.8A)
RTL  A 176 ( 4.0A)
RTL  A 176 (-3.4A)
RTL  A 176 ( 4.0A)
RTL  A 176 (-4.0A)
RTL  A 176 (-3.8A)
RTL  A 176 ( 4.7A)
RTL  A 176 ( 4.8A)
0.01A 1iiuA-1iiuA:
35.1
1iiuA-1iiuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IIU_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
5 / 11 LEU A  37
ALA A  57
MET A  73
LEU A  97
HIS A 117
RTL  A 176 ( 4.5A)
RTL  A 176 ( 3.8A)
RTL  A 176 ( 4.0A)
RTL  A 176 (-4.0A)
RTL  A 176 ( 4.6A)
1.26A 1iiuA-1iiuA:
35.1
1iiuA-1iiuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KGL_A_RTLA175_0
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
6 / 12 LEU A  29
ALA A  33
PRO A  38
LYS A  40
SER A  55
ILE A  77
RTL  A 135 (-3.8A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.4A)
RTL  A 135 ( 4.4A)
RTL  A 135 ( 4.4A)
RTL  A 135 (-3.5A)
1.13A 1kglA-1mx8A:
19.5
1kglA-1mx8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KGL_A_RTLA175_0
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
7 / 12 LEU A  29
PRO A  38
LYS A  40
SER A  55
TYR A  60
GLY A  76
ILE A  77
RTL  A 135 (-3.8A)
RTL  A 135 ( 4.4A)
RTL  A 135 ( 4.4A)
RTL  A 135 ( 4.4A)
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.9A)
RTL  A 135 (-3.5A)
1.08A 1kglA-1mx8A:
19.5
1kglA-1mx8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KGL_A_RTLA175_0
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
5 / 12 PHE A  16
ALA A  33
LYS A  40
SER A  55
PHE A  57
RTL  A 135 ( 4.6A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.4A)
RTL  A 135 ( 4.4A)
None
1.27A 1kglA-1mx8A:
19.5
1kglA-1mx8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KGL_A_RTLA175_0
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
6 / 12 PHE A  16
LEU A  29
ALA A  33
PRO A  38
LYS A  40
SER A  55
RTL  A 135 ( 4.6A)
RTL  A 135 (-3.8A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.4A)
RTL  A 135 ( 4.4A)
RTL  A 135 ( 4.4A)
1.05A 1kglA-1mx8A:
19.5
1kglA-1mx8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KGL_A_RTLA175_1
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
4 / 7 LEU A  36
ILE A  51
THR A  53
MET A  62
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.3A)
RTL  A 135 (-2.9A)
0.73A 1kglA-1mx8A:
19.5
1kglA-1mx8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
7 / 7 LEU A  35
LEU A  37
MET A  73
MET A  88
TYR A  90
LEU A  97
GLN A  98
RTL  A 176 (-4.5A)
RTL  A 176 ( 4.5A)
RTL  A 176 ( 4.0A)
RTL  A 176 (-3.4A)
RTL  A 176 ( 4.0A)
RTL  A 176 (-4.0A)
RTL  A 176 (-3.8A)
0.40A 1kt3A-1iiuA:
28.1
1kt3A-1iiuA:
79.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
5 / 12 ALA A  55
ALA A  43
MET A  88
HIS A 104
TYR A 133
RTL  A 176 ( 3.8A)
RTL  A 176 ( 4.1A)
RTL  A 176 (-3.4A)
RTL  A 176 ( 4.7A)
None
1.15A 1kt4A-1iiuA:
31.6
1kt4A-1iiuA:
79.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
12 / 12 LEU A  35
LEU A  37
ALA A  55
ALA A  57
VAL A  61
MET A  73
MET A  88
TYR A  90
GLN A  98
HIS A 104
ARG A 121
TYR A 133
RTL  A 176 (-4.5A)
RTL  A 176 ( 4.5A)
RTL  A 176 ( 3.8A)
RTL  A 176 ( 3.8A)
None
RTL  A 176 ( 4.0A)
RTL  A 176 (-3.4A)
RTL  A 176 ( 4.0A)
RTL  A 176 (-3.8A)
RTL  A 176 ( 4.7A)
RTL  A 176 ( 4.8A)
None
0.33A 1kt4A-1iiuA:
31.6
1kt4A-1iiuA:
79.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
6 / 12 LEU A  37
ALA A  57
VAL A  61
MET A  73
GLN A  98
HIS A 117
RTL  A 176 ( 4.5A)
RTL  A 176 ( 3.8A)
None
RTL  A 176 ( 4.0A)
RTL  A 176 (-3.8A)
RTL  A 176 ( 4.6A)
1.36A 1kt4A-1iiuA:
31.6
1kt4A-1iiuA:
79.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
5 / 12 ALA A  55
ALA A  43
MET A  88
HIS A 104
TYR A 133
RTL  A 176 ( 3.8A)
RTL  A 176 ( 4.1A)
RTL  A 176 (-3.4A)
RTL  A 176 ( 4.7A)
None
1.20A 1kt5A-1iiuA:
31.6
1kt5A-1iiuA:
80.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
12 / 12 LEU A  35
LEU A  37
PHE A  45
ALA A  55
ALA A  57
MET A  73
MET A  88
TYR A  90
LEU A  97
HIS A 104
ARG A 121
TYR A 133
RTL  A 176 (-4.5A)
RTL  A 176 ( 4.5A)
RTL  A 176 ( 4.8A)
RTL  A 176 ( 3.8A)
RTL  A 176 ( 3.8A)
RTL  A 176 ( 4.0A)
RTL  A 176 (-3.4A)
RTL  A 176 ( 4.0A)
RTL  A 176 (-4.0A)
RTL  A 176 ( 4.7A)
RTL  A 176 ( 4.8A)
None
0.33A 1kt5A-1iiuA:
31.6
1kt5A-1iiuA:
80.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
5 / 12 LEU A  37
ALA A  57
MET A  73
LEU A  97
HIS A 117
RTL  A 176 ( 4.5A)
RTL  A 176 ( 3.8A)
RTL  A 176 ( 4.0A)
RTL  A 176 (-4.0A)
RTL  A 176 ( 4.6A)
1.31A 1kt5A-1iiuA:
31.6
1kt5A-1iiuA:
80.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
11 / 11 LEU A  35
LEU A  37
ALA A  55
VAL A  61
MET A  73
MET A  88
TYR A  90
LEU A  97
GLN A  98
HIS A 104
ARG A 121
RTL  A 176 (-4.5A)
RTL  A 176 ( 4.5A)
RTL  A 176 ( 3.8A)
None
RTL  A 176 ( 4.0A)
RTL  A 176 (-3.4A)
RTL  A 176 ( 4.0A)
RTL  A 176 (-4.0A)
RTL  A 176 (-3.8A)
RTL  A 176 ( 4.7A)
RTL  A 176 ( 4.8A)
0.33A 1kt6A-1iiuA:
31.8
1kt6A-1iiuA:
79.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
6 / 11 LEU A  37
VAL A  61
MET A  73
LEU A  97
GLN A  98
HIS A 117
RTL  A 176 ( 4.5A)
None
RTL  A 176 ( 4.0A)
RTL  A 176 (-4.0A)
RTL  A 176 (-3.8A)
RTL  A 176 ( 4.6A)
1.29A 1kt6A-1iiuA:
31.8
1kt6A-1iiuA:
79.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
11 / 11 LEU A  35
LEU A  37
ALA A  55
VAL A  61
MET A  73
MET A  88
TYR A  90
LEU A  97
GLN A  98
HIS A 104
ARG A 121
RTL  A 176 (-4.5A)
RTL  A 176 ( 4.5A)
RTL  A 176 ( 3.8A)
None
RTL  A 176 ( 4.0A)
RTL  A 176 (-3.4A)
RTL  A 176 ( 4.0A)
RTL  A 176 (-4.0A)
RTL  A 176 (-3.8A)
RTL  A 176 ( 4.7A)
RTL  A 176 ( 4.8A)
0.32A 1kt7A-1iiuA:
32.0
1kt7A-1iiuA:
79.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
6 / 11 LEU A  37
VAL A  61
MET A  73
LEU A  97
GLN A  98
HIS A 117
RTL  A 176 ( 4.5A)
None
RTL  A 176 ( 4.0A)
RTL  A 176 (-4.0A)
RTL  A 176 (-3.8A)
RTL  A 176 ( 4.6A)
1.29A 1kt7A-1iiuA:
32.0
1kt7A-1iiuA:
79.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MX8_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
12 / 12 PHE A  16
TYR A  19
LEU A  20
ALA A  33
LEU A  36
PRO A  38
THR A  53
ARG A  58
TYR A  60
MET A  62
PHE A  64
ILE A  77
RTL  A 135 ( 4.6A)
None
RTL  A 135 ( 4.7A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.4A)
RTL  A 135 ( 4.3A)
None
RTL  A 135 ( 4.6A)
RTL  A 135 (-2.9A)
RTL  A 135 ( 3.8A)
RTL  A 135 (-3.5A)
0.00A 1mx8A-1mx8A:
28.4
1mx8A-1mx8A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
5 / 12 PHE A  77
LEU A  37
VAL A  41
PHE A 135
ALA A  43
None
RTL  A 176 ( 4.5A)
None
RTL  A 176 ( 4.2A)
RTL  A 176 ( 4.1A)
1.05A 1q23A-1iiuA:
undetectable
1q23B-1iiuA:
0.0
1q23A-1iiuA:
21.10
1q23B-1iiuA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_D_FUAD705_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
5 / 12 PHE A  77
LEU A  37
VAL A  41
PHE A 135
ALA A  43
None
RTL  A 176 ( 4.5A)
None
RTL  A 176 ( 4.2A)
RTL  A 176 ( 4.1A)
1.00A 1q23D-1iiuA:
0.0
1q23E-1iiuA:
undetectable
1q23D-1iiuA:
21.10
1q23E-1iiuA:
21.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QAB_E_RTLE1_0
(PROTEIN (RETINOL
BINDING PROTEIN))
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
5 / 11 PHE A  36
ALA A  43
MET A  88
HIS A 104
TYR A 133
None
RTL  A 176 ( 4.1A)
RTL  A 176 (-3.4A)
RTL  A 176 ( 4.7A)
None
1.14A 1qabE-1iiuA:
26.5
1qabE-1iiuA:
84.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QAB_E_RTLE1_0
(PROTEIN (RETINOL
BINDING PROTEIN))
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
11 / 11 PHE A  36
LEU A  37
ALA A  57
VAL A  61
MET A  73
MET A  88
TYR A  90
LEU A  97
GLN A  98
HIS A 104
TYR A 133
None
RTL  A 176 ( 4.5A)
RTL  A 176 ( 3.8A)
None
RTL  A 176 ( 4.0A)
RTL  A 176 (-3.4A)
RTL  A 176 ( 4.0A)
RTL  A 176 (-4.0A)
RTL  A 176 (-3.8A)
RTL  A 176 ( 4.7A)
None
0.82A 1qabE-1iiuA:
26.5
1qabE-1iiuA:
84.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QAB_E_RTLE1_0
(PROTEIN (RETINOL
BINDING PROTEIN))
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
8 / 11 PHE A  36
LEU A  37
VAL A  61
MET A  73
LEU A  97
GLN A  98
HIS A 117
TYR A 133
None
RTL  A 176 ( 4.5A)
None
RTL  A 176 ( 4.0A)
RTL  A 176 (-4.0A)
RTL  A 176 (-3.8A)
RTL  A 176 ( 4.6A)
None
1.30A 1qabE-1iiuA:
26.5
1qabE-1iiuA:
84.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QAB_F_RTLF2_0
(PROTEIN (RETINOL
BINDING PROTEIN))
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
6 / 12 PHE A  36
ALA A  43
LEU A  63
MET A  73
LEU A  97
GLN A  98
None
RTL  A 176 ( 4.1A)
None
RTL  A 176 ( 4.0A)
RTL  A 176 (-4.0A)
RTL  A 176 (-3.8A)
1.45A 1qabF-1iiuA:
28.7
1qabF-1iiuA:
84.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QAB_F_RTLF2_0
(PROTEIN (RETINOL
BINDING PROTEIN))
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
12 / 12 PHE A  36
ALA A  55
ALA A  57
LEU A  63
MET A  73
GLY A  75
PHE A  77
MET A  88
TYR A  90
LEU A  97
GLN A  98
HIS A 104
None
RTL  A 176 ( 3.8A)
RTL  A 176 ( 3.8A)
None
RTL  A 176 ( 4.0A)
RTL  A 176 ( 4.0A)
None
RTL  A 176 (-3.4A)
RTL  A 176 ( 4.0A)
RTL  A 176 (-4.0A)
RTL  A 176 (-3.8A)
RTL  A 176 ( 4.7A)
0.80A 1qabF-1iiuA:
28.7
1qabF-1iiuA:
84.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RBP_A_RTLA183_0
(PLASMA
RETINOL-BINDING
PROTEIN PRECURSOR)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
12 / 12 LEU A  35
LEU A  37
ALA A  43
PHE A  45
ALA A  55
ALA A  57
VAL A  61
MET A  73
MET A  88
LEU A  97
GLN A  98
HIS A 104
RTL  A 176 (-4.5A)
RTL  A 176 ( 4.5A)
RTL  A 176 ( 4.1A)
RTL  A 176 ( 4.8A)
RTL  A 176 ( 3.8A)
RTL  A 176 ( 3.8A)
None
RTL  A 176 ( 4.0A)
RTL  A 176 (-3.4A)
RTL  A 176 (-4.0A)
RTL  A 176 (-3.8A)
RTL  A 176 ( 4.7A)
0.39A 1rbpA-1iiuA:
31.9
1rbpA-1iiuA:
84.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RBP_A_RTLA183_0
(PLASMA
RETINOL-BINDING
PROTEIN PRECURSOR)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
5 / 12 LEU A  35
LEU A  37
PHE A  77
MET A  73
LEU A  97
RTL  A 176 (-4.5A)
RTL  A 176 ( 4.5A)
None
RTL  A 176 ( 4.0A)
RTL  A 176 (-4.0A)
1.30A 1rbpA-1iiuA:
31.9
1rbpA-1iiuA:
84.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
9 / 10 LEU A  37
ALA A  55
ALA A  57
VAL A  61
MET A  73
LEU A  97
GLN A  98
ASP A 102
PHE A 135
RTL  A 176 ( 4.5A)
RTL  A 176 ( 3.8A)
RTL  A 176 ( 3.8A)
None
RTL  A 176 ( 4.0A)
RTL  A 176 (-4.0A)
RTL  A 176 (-3.8A)
None
RTL  A 176 ( 4.2A)
0.62A 1rlbE-1iiuA:
30.8
1rlbE-1iiuA:
80.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RLB_F_REAF177_1
(RETINOL BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
10 / 11 PHE A  36
LEU A  37
ALA A  55
ALA A  57
VAL A  61
LEU A  63
MET A  73
MET A  88
LEU A  97
GLN A  98
None
RTL  A 176 ( 4.5A)
RTL  A 176 ( 3.8A)
RTL  A 176 ( 3.8A)
None
None
RTL  A 176 ( 4.0A)
RTL  A 176 (-3.4A)
RTL  A 176 (-4.0A)
RTL  A 176 (-3.8A)
0.65A 1rlbF-1iiuA:
30.5
1rlbF-1iiuA:
80.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RLB_F_REAF177_1
(RETINOL BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
10 / 11 PHE A  36
LEU A  37
ALA A  55
ALA A  57
VAL A  61
MET A  73
MET A  88
TYR A  90
LEU A  97
GLN A  98
None
RTL  A 176 ( 4.5A)
RTL  A 176 ( 3.8A)
RTL  A 176 ( 3.8A)
None
RTL  A 176 ( 4.0A)
RTL  A 176 (-3.4A)
RTL  A 176 ( 4.0A)
RTL  A 176 (-4.0A)
RTL  A 176 (-3.8A)
0.54A 1rlbF-1iiuA:
30.5
1rlbF-1iiuA:
80.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
4 / 6 MET A  73
VAL A  93
LEU A  97
PHE A  96
RTL  A 176 ( 4.0A)
None
RTL  A 176 (-4.0A)
None
1.15A 1x8vA-1iiuA:
0.0
1x8vA-1iiuA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
5 / 10 ALA A  57
THR A  56
ALA A  55
ALA A  43
GLY A  92
RTL  A 176 ( 3.8A)
None
RTL  A 176 ( 3.8A)
RTL  A 176 ( 4.1A)
None
0.87A 2f16K-1iiuA:
undetectable
2f16L-1iiuA:
undetectable
2f16K-1iiuA:
18.47
2f16L-1iiuA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
5 / 10 ALA A  57
THR A  56
ALA A  55
ALA A  43
GLY A  92
RTL  A 176 ( 3.8A)
None
RTL  A 176 ( 3.8A)
RTL  A 176 ( 4.1A)
None
0.87A 2f16Y-1iiuA:
undetectable
2f16Z-1iiuA:
undetectable
2f16Y-1iiuA:
18.47
2f16Z-1iiuA:
21.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FR3_A_REAA300_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
2)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
5 / 12 PHE A  16
LEU A  20
ILE A  32
ALA A  33
THR A  53
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.7A)
None
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.3A)
0.87A 2fr3A-1mx8A:
16.5
2fr3A-1mx8A:
44.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BSZ_E_RTLE177_0
(PLASMA
RETINOL-BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
10 / 11 LEU A  37
ALA A  43
ALA A  57
VAL A  61
MET A  73
MET A  88
LEU A  97
GLN A  98
HIS A 104
PHE A 135
RTL  A 176 ( 4.5A)
RTL  A 176 ( 4.1A)
RTL  A 176 ( 3.8A)
None
RTL  A 176 ( 4.0A)
RTL  A 176 (-3.4A)
RTL  A 176 (-4.0A)
RTL  A 176 (-3.8A)
RTL  A 176 ( 4.7A)
RTL  A 176 ( 4.2A)
0.43A 3bszE-1iiuA:
30.1
3bszE-1iiuA:
85.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BSZ_E_RTLE177_0
(PLASMA
RETINOL-BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
7 / 11 LEU A  37
ALA A  57
VAL A  61
MET A  73
LEU A  97
GLN A  98
HIS A 117
RTL  A 176 ( 4.5A)
RTL  A 176 ( 3.8A)
None
RTL  A 176 ( 4.0A)
RTL  A 176 (-4.0A)
RTL  A 176 (-3.8A)
RTL  A 176 ( 4.6A)
1.29A 3bszE-1iiuA:
30.1
3bszE-1iiuA:
85.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BSZ_F_RTLF178_0
(PLASMA
RETINOL-BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
5 / 11 ALA A  57
ALA A  55
MET A  88
HIS A 104
PHE A 135
RTL  A 176 ( 3.8A)
RTL  A 176 ( 3.8A)
RTL  A 176 (-3.4A)
RTL  A 176 ( 4.7A)
RTL  A 176 ( 4.2A)
1.34A 3bszF-1iiuA:
30.0
3bszF-1iiuA:
85.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BSZ_F_RTLF178_0
(PLASMA
RETINOL-BINDING
PROTEIN)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
10 / 11 LEU A  37
ALA A  43
PHE A  45
ALA A  55
MET A  73
MET A  88
TYR A  90
GLN A  98
HIS A 104
PHE A 135
RTL  A 176 ( 4.5A)
RTL  A 176 ( 4.1A)
RTL  A 176 ( 4.8A)
RTL  A 176 ( 3.8A)
RTL  A 176 ( 4.0A)
RTL  A 176 (-3.4A)
RTL  A 176 ( 4.0A)
RTL  A 176 (-3.8A)
RTL  A 176 ( 4.7A)
RTL  A 176 ( 4.2A)
0.40A 3bszF-1iiuA:
30.0
3bszF-1iiuA:
85.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
5 / 12 ALA A  57
THR A  56
ALA A  55
ALA A  43
GLY A  92
RTL  A 176 ( 3.8A)
None
RTL  A 176 ( 3.8A)
RTL  A 176 ( 4.1A)
None
0.87A 3mg0Y-1iiuA:
0.9
3mg0Z-1iiuA:
0.0
3mg0Y-1iiuA:
18.47
3mg0Z-1iiuA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_2
(FIV PROTEASE)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
5 / 10 VAL A  61
GLY A  92
ILE A  74
VAL A  41
LEU A  37
None
None
None
None
RTL  A 176 ( 4.5A)
0.73A 3ogpB-1iiuA:
undetectable
3ogpB-1iiuA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)
1fml RETINOL DEHYDRATASE
(Spodoptera
frugiperda)
3 / 3 TYR A 120
THR A  33
GLU A 118
RTL  A 401 ( 4.5A)
None
None
0.75A 4df3A-1fmlA:
0.7
4df3A-1fmlA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)
1fml RETINOL DEHYDRATASE
(Spodoptera
frugiperda)
3 / 3 TYR A 120
THR A  33
GLU A 118
RTL  A 401 ( 4.5A)
None
None
0.76A 4df3B-1fmlA:
0.7
4df3B-1fmlA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOV_A_KOVA204_1
(UNCHARACTERIZED
PROTEIN)
1fml RETINOL DEHYDRATASE
(Spodoptera
frugiperda)
5 / 12 TYR A 141
TYR A 105
GLY A 108
TYR A  46
LEU A 201
None
RTL  A 401 (-4.6A)
None
None
RTL  A 401 ( 4.3A)
1.48A 4kovA-1fmlA:
0.0
4kovA-1fmlA:
18.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
6 / 12 LEU A  23
ILE A  51
ARG A  58
TYR A  60
MET A  62
ILE A  77
None
RTL  A 135 ( 4.6A)
None
RTL  A 135 ( 4.6A)
RTL  A 135 (-2.9A)
RTL  A 135 (-3.5A)
1.49A 5h8tA-1mx8A:
20.1
5h8tA-1mx8A:
92.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
10 / 12 PHE A  16
TYR A  19
LEU A  20
LEU A  29
ALA A  33
ILE A  51
SER A  55
ARG A  58
MET A  62
ILE A  77
RTL  A 135 ( 4.6A)
None
RTL  A 135 ( 4.7A)
RTL  A 135 (-3.8A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.4A)
None
RTL  A 135 (-2.9A)
RTL  A 135 (-3.5A)
1.00A 5h8tA-1mx8A:
20.1
5h8tA-1mx8A:
92.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
10 / 12 PHE A  16
TYR A  19
LEU A  29
ALA A  33
ILE A  51
SER A  55
ARG A  58
TYR A  60
MET A  62
ILE A  77
RTL  A 135 ( 4.6A)
None
RTL  A 135 (-3.8A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.4A)
None
RTL  A 135 ( 4.6A)
RTL  A 135 (-2.9A)
RTL  A 135 (-3.5A)
1.00A 5h8tA-1mx8A:
20.1
5h8tA-1mx8A:
92.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
8 / 12 PHE A  16
TYR A  19
ALA A  33
ILE A  51
SER A  55
ARG A  58
MET A  62
ILE A  77
RTL  A 135 ( 4.6A)
None
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.4A)
None
RTL  A 135 (-2.9A)
RTL  A 135 (-3.5A)
0.92A 5hbsA-1mx8A:
19.9
5hbsA-1mx8A:
92.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
8 / 12 PHE A  16
TYR A  19
ALA A  33
PRO A  38
ILE A  51
ARG A  58
MET A  62
ILE A  77
RTL  A 135 ( 4.6A)
None
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.4A)
RTL  A 135 ( 4.6A)
None
RTL  A 135 (-2.9A)
RTL  A 135 (-3.5A)
0.95A 5hbsA-1mx8A:
19.9
5hbsA-1mx8A:
92.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
8 / 12 PHE A  16
TYR A  19
LEU A  29
ALA A  33
ILE A  51
SER A  55
MET A  62
ILE A  77
RTL  A 135 ( 4.6A)
None
RTL  A 135 (-3.8A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.4A)
RTL  A 135 (-2.9A)
RTL  A 135 (-3.5A)
0.92A 5hbsA-1mx8A:
19.9
5hbsA-1mx8A:
92.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
8 / 12 PHE A  16
TYR A  19
LEU A  29
ALA A  33
PRO A  38
ILE A  51
MET A  62
ILE A  77
RTL  A 135 ( 4.6A)
None
RTL  A 135 (-3.8A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.4A)
RTL  A 135 ( 4.6A)
RTL  A 135 (-2.9A)
RTL  A 135 (-3.5A)
0.96A 5hbsA-1mx8A:
19.9
5hbsA-1mx8A:
92.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
8 / 12 PHE A  16
TYR A  19
VAL A  25
LEU A  29
ALA A  33
ILE A  51
SER A  55
ILE A  77
RTL  A 135 ( 4.6A)
None
None
RTL  A 135 (-3.8A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.4A)
RTL  A 135 (-3.5A)
0.86A 5hbsA-1mx8A:
19.9
5hbsA-1mx8A:
92.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
8 / 12 PHE A  16
TYR A  19
VAL A  25
LEU A  29
ALA A  33
PRO A  38
ILE A  51
ILE A  77
RTL  A 135 ( 4.6A)
None
None
RTL  A 135 (-3.8A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.4A)
RTL  A 135 ( 4.6A)
RTL  A 135 (-3.5A)
0.88A 5hbsA-1mx8A:
19.9
5hbsA-1mx8A:
92.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
6 / 12 VAL A  25
LEU A  29
ALA A  33
PRO A  38
ILE A  61
ILE A  77
None
RTL  A 135 (-3.8A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.4A)
None
RTL  A 135 (-3.5A)
1.33A 5hbsA-1mx8A:
19.9
5hbsA-1mx8A:
92.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
5 / 9 ALA A  57
THR A  56
ALA A  55
ALA A  43
GLY A  92
RTL  A 176 ( 3.8A)
None
RTL  A 176 ( 3.8A)
RTL  A 176 ( 4.1A)
None
0.85A 5l5zK-1iiuA:
undetectable
5l5zL-1iiuA:
undetectable
5l5zK-1iiuA:
19.00
5l5zL-1iiuA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
5 / 9 ALA A  57
THR A  56
ALA A  55
ALA A  43
GLY A  92
RTL  A 176 ( 3.8A)
None
RTL  A 176 ( 3.8A)
RTL  A 176 ( 4.1A)
None
0.85A 5l5zY-1iiuA:
undetectable
5l5zZ-1iiuA:
undetectable
5l5zY-1iiuA:
19.00
5l5zZ-1iiuA:
21.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
7 / 12 PHE A  16
LEU A  29
ALA A  33
PRO A  38
ARG A  58
TYR A  60
ILE A  77
RTL  A 135 ( 4.6A)
RTL  A 135 (-3.8A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.4A)
None
RTL  A 135 ( 4.6A)
RTL  A 135 (-3.5A)
0.88A 5ljbA-1mx8A:
19.7
5ljbA-1mx8A:
96.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
7 / 12 PHE A  16
LEU A  29
ALA A  33
PRO A  38
TYR A  60
MET A  62
ILE A  77
RTL  A 135 ( 4.6A)
RTL  A 135 (-3.8A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.4A)
RTL  A 135 ( 4.6A)
RTL  A 135 (-2.9A)
RTL  A 135 (-3.5A)
0.88A 5ljbA-1mx8A:
19.7
5ljbA-1mx8A:
96.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
7 / 12 PHE A  16
LEU A  29
ALA A  33
SER A  55
TYR A  60
MET A  62
ILE A  77
RTL  A 135 ( 4.6A)
RTL  A 135 (-3.8A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.4A)
RTL  A 135 ( 4.6A)
RTL  A 135 (-2.9A)
RTL  A 135 (-3.5A)
0.94A 5ljbA-1mx8A:
19.7
5ljbA-1mx8A:
96.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
6 / 12 PHE A  16
TYR A  19
ALA A  33
SER A  55
PHE A  57
MET A  62
RTL  A 135 ( 4.6A)
None
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.4A)
None
RTL  A 135 (-2.9A)
1.23A 5ljbA-1mx8A:
19.7
5ljbA-1mx8A:
96.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
7 / 12 PHE A  16
TYR A  19
LEU A  29
ALA A  33
PRO A  38
ARG A  58
ILE A  77
RTL  A 135 ( 4.6A)
None
RTL  A 135 (-3.8A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.4A)
None
RTL  A 135 (-3.5A)
0.83A 5ljbA-1mx8A:
19.7
5ljbA-1mx8A:
96.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
7 / 12 PHE A  16
TYR A  19
LEU A  29
ALA A  33
PRO A  38
MET A  62
ILE A  77
RTL  A 135 ( 4.6A)
None
RTL  A 135 (-3.8A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.4A)
RTL  A 135 (-2.9A)
RTL  A 135 (-3.5A)
0.94A 5ljbA-1mx8A:
19.7
5ljbA-1mx8A:
96.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
7 / 12 PHE A  16
TYR A  19
LEU A  29
ALA A  33
SER A  55
MET A  62
ILE A  77
RTL  A 135 ( 4.6A)
None
RTL  A 135 (-3.8A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.4A)
RTL  A 135 (-2.9A)
RTL  A 135 (-3.5A)
0.95A 5ljbA-1mx8A:
19.7
5ljbA-1mx8A:
96.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LJB_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
4 / 8 LEU A  20
LEU A  36
LYS A  40
ILE A  51
RTL  A 135 ( 4.7A)
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.4A)
RTL  A 135 ( 4.6A)
0.85A 5ljbA-1mx8A:
19.7
5ljbA-1mx8A:
96.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
5 / 12 PHE A  16
TYR A  19
ALA A  33
SER A  55
PHE A  57
RTL  A 135 ( 4.6A)
None
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.4A)
None
1.21A 5ljcA-1mx8A:
19.7
5ljcA-1mx8A:
95.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
9 / 12 PHE A  16
TYR A  19
LEU A  29
ALA A  33
LEU A  36
PRO A  38
ARG A  58
TYR A  60
ILE A  77
RTL  A 135 ( 4.6A)
None
RTL  A 135 (-3.8A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.4A)
None
RTL  A 135 ( 4.6A)
RTL  A 135 (-3.5A)
0.89A 5ljcA-1mx8A:
19.7
5ljcA-1mx8A:
95.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
8 / 12 PHE A  16
TYR A  19
LEU A  29
ALA A  33
LEU A  36
SER A  55
TYR A  60
ILE A  77
RTL  A 135 ( 4.6A)
None
RTL  A 135 (-3.8A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.4A)
RTL  A 135 ( 4.6A)
RTL  A 135 (-3.5A)
0.94A 5ljcA-1mx8A:
19.7
5ljcA-1mx8A:
95.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LJE_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
6 / 12 PHE A  16
LEU A  20
LEU A  29
ALA A  33
PRO A  38
ARG A  58
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.7A)
RTL  A 135 (-3.8A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.4A)
None
0.88A 5ljeA-1mx8A:
19.8
5ljeA-1mx8A:
94.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LJE_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
6 / 12 PHE A  16
LEU A  20
LEU A  29
ALA A  33
SER A  55
ARG A  58
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.7A)
RTL  A 135 (-3.8A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.4A)
None
0.79A 5ljeA-1mx8A:
19.8
5ljeA-1mx8A:
94.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LJE_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
7 / 12 PHE A  16
LEU A  29
ALA A  33
PRO A  38
ARG A  58
TYR A  60
ILE A  77
RTL  A 135 ( 4.6A)
RTL  A 135 (-3.8A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.4A)
None
RTL  A 135 ( 4.6A)
RTL  A 135 (-3.5A)
0.82A 5ljeA-1mx8A:
19.8
5ljeA-1mx8A:
94.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LJE_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
7 / 12 PHE A  16
LEU A  29
ALA A  33
SER A  55
ARG A  58
TYR A  60
ILE A  77
RTL  A 135 ( 4.6A)
RTL  A 135 (-3.8A)
RTL  A 135 ( 3.9A)
RTL  A 135 ( 4.4A)
None
RTL  A 135 ( 4.6A)
RTL  A 135 (-3.5A)
0.86A 5ljeA-1mx8A:
19.8
5ljeA-1mx8A:
94.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LJE_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO

(Rattus
norvegicus)
4 / 6 LEU A  36
ILE A  51
THR A  53
MET A  62
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.3A)
RTL  A 135 (-2.9A)
0.86A 5ljeA-1mx8A:
19.8
5ljeA-1mx8A:
94.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NU7_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 4)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
8 / 8 LEU A  37
ALA A  55
VAL A  61
MET A  73
MET A  88
TYR A  90
GLN A  98
HIS A 104
RTL  A 176 ( 4.5A)
RTL  A 176 ( 3.8A)
None
RTL  A 176 ( 4.0A)
RTL  A 176 (-3.4A)
RTL  A 176 ( 4.0A)
RTL  A 176 (-3.8A)
RTL  A 176 ( 4.7A)
0.36A 5nu7A-1iiuA:
31.7
5nu7A-1iiuA:
84.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NU7_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 4)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
5 / 8 LEU A  37
VAL A  61
MET A  73
GLN A  98
HIS A 117
RTL  A 176 ( 4.5A)
None
RTL  A 176 ( 4.0A)
RTL  A 176 (-3.8A)
RTL  A 176 ( 4.6A)
1.31A 5nu7A-1iiuA:
31.7
5nu7A-1iiuA:
84.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
5 / 11 ALA A  57
THR A  56
ALA A  55
ALA A  43
GLY A  92
RTL  A 176 ( 3.8A)
None
RTL  A 176 ( 3.8A)
RTL  A 176 ( 4.1A)
None
0.87A 6hwdK-1iiuA:
undetectable
6hwdL-1iiuA:
undetectable
6hwdK-1iiuA:
18.97
6hwdL-1iiuA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1iiu PLASMA
RETINOL-BINDING
PROTEIN

(Gallus
gallus)
5 / 11 ALA A  57
THR A  56
ALA A  55
ALA A  43
GLY A  92
RTL  A 176 ( 3.8A)
None
RTL  A 176 ( 3.8A)
RTL  A 176 ( 4.1A)
None
0.87A 6hwdY-1iiuA:
undetectable
6hwdZ-1iiuA:
undetectable
6hwdY-1iiuA:
18.97
6hwdZ-1iiuA:
19.41