SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'RRM'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDV_B_CL6B506_1 (CHOLESTEROL 24-HYDROXYLASE)	3wvs	PUTATIVE MONOOXYGENASE (Streptomyces sp. SN-593)	5 / 12	LEU A 176 ILE A 240 ALA A 241 GLU A 244 THR A 245	RRM A 502 (-4.9A) RRM A 502 ( 3.9A) HEM A 501 (-3.8A) None HEM A 501 (-3.3A)	0.73A	3mdvB-3wvsA: 32.3	3mdvB-3wvsA: 24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RRW_D_LURD705_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3wvs	PUTATIVE MONOOXYGENASE (Streptomyces sp. SN-593)	5 / 12	LEU A 25 SER A 26 LEU A 287 GLY A 288 SER A 291	None None HEM A 501 (-4.3A) RRM A 502 (-3.6A) None	1.05A	4rrwD-3wvsA: undetectable	4rrwD-3wvsA: 21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RRZ_D_LURD705_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3wvs	PUTATIVE MONOOXYGENASE (Streptomyces sp. SN-593)	5 / 12	LEU A 25 SER A 26 LEU A 287 GLY A 288 SER A 291	None None HEM A 501 (-4.3A) RRM A 502 (-3.6A) None	1.05A	4rrzD-3wvsA: undetectable	4rrzD-3wvsA: 21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y8W_B_STRB603_1 (CYTOCHROME P450 21-HYDROXYLASE)	3wvs	PUTATIVE MONOOXYGENASE (Streptomyces sp. SN-593)	5 / 12	VAL A 194 LEU A 193 ILE A 236 GLY A 237 LEU A 176	None None RRM A 502 (-4.2A) RRM A 502 (-3.7A) RRM A 502 (-4.9A)	1.11A	4y8wB-3wvsA: 32.9	4y8wB-3wvsA: 26.44

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3MDV_B_CL6B506_1","CHOLESTEROL 24-HYDROXYLASE","3wvs","PUTATIVE MONOOXYGENASE","Streptomyces sp. SN-593",5,"LEU A 176;ILE A 240;ALA A 241;GLU A 244;THR A 245","RRM A 502 (-4.9A);RRM A 502 ( 3.9A);HEM A 501 (-3.8A);None;HEM A 501 (-3.3A)","0.73A","3mdvB-3wvsA:32.3",null],["4RRW_D_LURD705_1","PROSTAGLANDIN G\/H SYNTHASE 2","3wvs","PUTATIVE MONOOXYGENASE","Streptomyces sp. SN-593",5,"LEU A  25;SER A  26;LEU A 287;GLY A 288;SER A 291","None;None;HEM A 501 (-4.3A);RRM A 502 (-3.6A);None","1.05A","4rrwD-3wvsA:undetectable","3mdvB-3wvsA:24.45"],["4RRZ_D_LURD705_1","PROSTAGLANDIN G\/H SYNTHASE 2","3wvs","PUTATIVE MONOOXYGENASE","Streptomyces sp. SN-593",5,"LEU A  25;SER A  26;LEU A 287;GLY A 288;SER A 291","None;None;HEM A 501 (-4.3A);RRM A 502 (-3.6A);None","1.05A","4rrzD-3wvsA:undetectable","4rrwD-3wvsA:21.71"],["4Y8W_B_STRB603_1","CYTOCHROME P450 21-HYDROXYLASE","3wvs","PUTATIVE MONOOXYGENASE","Streptomyces sp. SN-593",5,"VAL A 194;LEU A 193;ILE A 236;GLY A 237;LEU A 176","None;None;RRM A 502 (-4.2A);RRM A 502 (-3.7A);RRM A 502 (-4.9A)","1.11A","4y8wB-3wvsA:32.9","4rrzD-3wvsA:21.71"]]