SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'RNS'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		4 / 8 THR A 154
GLY A  65
HIS A 146
ILE A  67
 None
None
None
RNS  A1462 (-4.0A)
 0.75A 1gtnA-1de6A:
undetectable
1gtnB-1de6A:
0.0		 1gtnA-1de6A:
11.89
1gtnB-1de6A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		4 / 8 GLY A  65
HIS A 146
ILE A  67
THR A 154
 None
None
RNS  A1462 (-4.0A)
None
 0.81A 1utdF-1de6A:
undetectable
1utdG-1de6A:
0.0		 1utdF-1de6A:
11.89
1utdG-1de6A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XID_A_ASCA389_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		5 / 10 PHE A 144
TRP A 193
GLU A 234
ASP A 267
ASP A 334
 None
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
ZN  A 450 (-3.0A)
RNS  A1462 ( 3.0A)
 1.41A 1xidA-1de6A:
27.3		 1xidA-1de6A:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XID_A_ASCA389_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		7 / 10 TRP A  48
HIS A 103
PHE A 144
TRP A 193
GLU A 234
HIS A 270
ASP A 334
 RNS  A1462 ( 4.1A)
RNS  A1462 (-4.4A)
None
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 ( 3.5A)
RNS  A1462 ( 3.0A)
 0.79A 1xidA-1de6A:
27.3		 1xidA-1de6A:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XID_A_ASCA389_0
(D-XYLOSE ISOMERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		6 / 10 TRP A  57
PHE A 131
TRP A 179
GLU A 219
HIS A 257
ASP A 327
 RNS  A1001 (-3.5A)
None
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
MN  A1004 ( 3.4A)
RNS  A1001 ( 2.8A)
 0.36A 1xidA-4gjiA:
34.2		 1xidA-4gjiA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIH_A_SORA389_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		5 / 12 HIS A 103
PHE A 144
TRP A 193
LYS A 236
ASP A 302
 RNS  A1462 (-4.4A)
None
RNS  A1462 (-3.2A)
RNS  A1462 (-2.2A)
MN  A 451 ( 2.2A)
 1.04A 1xihA-1de6A:
27.4		 1xihA-1de6A:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIH_A_SORA389_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		7 / 12 TRP A  48
HIS A 103
PHE A 144
TRP A 193
LYS A 236
HIS A 270
ASP A 334
 RNS  A1462 ( 4.1A)
RNS  A1462 (-4.4A)
None
RNS  A1462 (-3.2A)
RNS  A1462 (-2.2A)
RNS  A1462 ( 3.5A)
RNS  A1462 ( 3.0A)
 0.78A 1xihA-1de6A:
27.4		 1xihA-1de6A:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIH_A_SORA389_0
(D-XYLOSE ISOMERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		5 / 12 TRP A  57
PHE A 131
TRP A 179
LYS A 221
ASP A 289
 RNS  A1001 (-3.5A)
None
RNS  A1001 (-3.3A)
RNS  A1001 (-2.7A)
MN  A1004 ( 2.6A)
 1.02A 1xihA-4gjiA:
34.3		 1xihA-4gjiA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIH_A_SORA389_0
(D-XYLOSE ISOMERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		6 / 12 TRP A  57
PHE A 131
TRP A 179
LYS A 221
HIS A 257
ASP A 327
 RNS  A1001 (-3.5A)
None
RNS  A1001 (-3.3A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
RNS  A1001 ( 2.8A)
 0.33A 1xihA-4gjiA:
34.3		 1xihA-4gjiA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		4 / 7 ASP A 124
SER A  99
GLN A 328
TRP A  57
 None
None
None
RNS  A1001 (-3.5A)
 0.95A 2cmlA-4gjiA:
undetectable		 2cmlA-4gjiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		4 / 8 ASP A 124
SER A  99
GLN A 328
TRP A  57
 None
None
None
RNS  A1001 (-3.5A)
 0.80A 2cmlB-4gjiA:
undetectable		 2cmlB-4gjiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		4 / 8 ASP A 124
SER A  99
GLN A 328
TRP A  57
 None
None
None
RNS  A1001 (-3.5A)
 0.92A 2cmlD-4gjiA:
undetectable		 2cmlD-4gjiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		5 / 12 TRP A 193
ASP A 267
ASP A 304
PHE A 336
ALA A  69
 RNS  A1462 (-3.2A)
ZN  A 450 (-3.0A)
MN  A 451 (-2.8A)
RNS  A1462 (-4.2A)
None
 1.24A 2qmjA-1de6A:
4.8		 2qmjA-1de6A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		5 / 12 LEU A  63
ASP A 267
ASP A 302
PHE A 336
HIS A 103
 None
ZN  A 450 (-3.0A)
MN  A 451 ( 2.2A)
RNS  A1462 (-4.2A)
RNS  A1462 (-4.4A)
 1.29A 2x2iB-1de6A:
5.1		 2x2iB-1de6A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		5 / 12 HIS A 103
TRP A 193
GLU A 234
HIS A 270
ASP A 304
 RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 ( 3.5A)
MN  A 451 (-2.8A)
 1.34A 2xinA-1de6A:
26.8		 2xinA-1de6A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		5 / 12 HIS A 103
TRP A 193
GLU A 234
HIS A 270
ASP A 334
 RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 ( 3.5A)
RNS  A1462 ( 3.0A)
 1.27A 2xinA-1de6A:
26.8		 2xinA-1de6A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		7 / 12 TRP A  48
HIS A 103
TRP A 193
GLU A 234
LYS A 236
ASP A 302
ASP A 334
 RNS  A1462 ( 4.1A)
RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 (-2.2A)
MN  A 451 ( 2.2A)
RNS  A1462 ( 3.0A)
 0.94A 2xinA-1de6A:
26.8		 2xinA-1de6A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		7 / 12 TRP A  48
HIS A 103
TRP A 193
GLU A 234
LYS A 236
HIS A 270
ASP A 334
 RNS  A1462 ( 4.1A)
RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 (-2.2A)
RNS  A1462 ( 3.5A)
RNS  A1462 ( 3.0A)
 0.63A 2xinA-1de6A:
26.8		 2xinA-1de6A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		6 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
ASP A 289
ASP A 327
 RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 2.6A)
RNS  A1001 ( 2.8A)
 0.76A 2xinA-4gjiA:
33.8		 2xinA-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		6 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
HIS A 257
ASP A 327
 RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
RNS  A1001 ( 2.8A)
 0.30A 2xinA-4gjiA:
33.8		 2xinA-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		6 / 12 TRP A  48
HIS A 103
TRP A 193
GLU A 234
ASP A 302
ASP A 334
 RNS  A1462 ( 4.1A)
RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
MN  A 451 ( 2.2A)
RNS  A1462 ( 3.0A)
 1.05A 2xinB-1de6A:
26.8		 2xinB-1de6A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		7 / 12 TRP A  48
HIS A 103
TRP A 193
GLU A 234
LYS A 236
HIS A 270
ASP A 334
 RNS  A1462 ( 4.1A)
RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 (-2.2A)
RNS  A1462 ( 3.5A)
RNS  A1462 ( 3.0A)
 0.63A 2xinB-1de6A:
26.8		 2xinB-1de6A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		6 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
ASP A 289
ASP A 327
 RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 2.6A)
RNS  A1001 ( 2.8A)
 0.89A 2xinB-4gjiA:
33.7		 2xinB-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		6 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
HIS A 257
ASP A 327
 RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
RNS  A1001 ( 2.8A)
 0.31A 2xinB-4gjiA:
33.7		 2xinB-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		5 / 12 HIS A 103
TRP A 193
GLU A 234
HIS A 270
ASP A 304
 RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 ( 3.5A)
MN  A 451 (-2.8A)
 1.34A 2xinC-1de6A:
26.7		 2xinC-1de6A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		5 / 12 HIS A 103
TRP A 193
GLU A 234
HIS A 270
ASP A 334
 RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 ( 3.5A)
RNS  A1462 ( 3.0A)
 1.26A 2xinC-1de6A:
26.7		 2xinC-1de6A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		7 / 12 TRP A  48
HIS A 103
TRP A 193
GLU A 234
LYS A 236
ASP A 302
ASP A 334
 RNS  A1462 ( 4.1A)
RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 (-2.2A)
MN  A 451 ( 2.2A)
RNS  A1462 ( 3.0A)
 0.98A 2xinC-1de6A:
26.7		 2xinC-1de6A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		7 / 12 TRP A  48
HIS A 103
TRP A 193
GLU A 234
LYS A 236
HIS A 270
ASP A 334
 RNS  A1462 ( 4.1A)
RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 (-2.2A)
RNS  A1462 ( 3.5A)
RNS  A1462 ( 3.0A)
 0.61A 2xinC-1de6A:
26.7		 2xinC-1de6A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		6 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
ASP A 289
ASP A 327
 RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 2.6A)
RNS  A1001 ( 2.8A)
 0.83A 2xinC-4gjiA:
33.8		 2xinC-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		6 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
HIS A 257
ASP A 327
 RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
RNS  A1001 ( 2.8A)
 0.33A 2xinC-4gjiA:
33.8		 2xinC-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		5 / 12 HIS A 103
TRP A 193
GLU A 234
HIS A 270
ASP A 334
 RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 ( 3.5A)
RNS  A1462 ( 3.0A)
 1.31A 2xinD-1de6A:
26.8		 2xinD-1de6A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		6 / 12 TRP A  48
HIS A 103
TRP A 193
GLU A 234
ASP A 302
ASP A 334
 RNS  A1462 ( 4.1A)
RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
MN  A 451 ( 2.2A)
RNS  A1462 ( 3.0A)
 1.07A 2xinD-1de6A:
26.8		 2xinD-1de6A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		7 / 12 TRP A  48
HIS A 103
TRP A 193
GLU A 234
LYS A 236
HIS A 270
ASP A 334
 RNS  A1462 ( 4.1A)
RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 (-2.2A)
RNS  A1462 ( 3.5A)
RNS  A1462 ( 3.0A)
 0.63A 2xinD-1de6A:
26.8		 2xinD-1de6A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		6 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
ASP A 289
ASP A 327
 RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 2.6A)
RNS  A1001 ( 2.8A)
 0.88A 2xinD-4gjiA:
33.7		 2xinD-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		6 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
HIS A 257
ASP A 327
 RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
RNS  A1001 ( 2.8A)
 0.29A 2xinD-4gjiA:
33.7		 2xinD-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		7 / 12 TRP A  48
HIS A 103
TRP A 193
LYS A 236
HIS A 270
ASP A 302
ASP A 334
 RNS  A1462 ( 4.1A)
RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
RNS  A1462 (-2.2A)
RNS  A1462 ( 3.5A)
MN  A 451 ( 2.2A)
RNS  A1462 ( 3.0A)
 0.75A 3ximA-1de6A:
26.9		 3ximA-1de6A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		6 / 12 TRP A  57
TRP A 179
LYS A 221
HIS A 257
ASP A 289
ASP A 327
 RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
MN  A1004 ( 2.6A)
RNS  A1001 ( 2.8A)
 0.47A 3ximA-4gjiA:
33.8		 3ximA-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		8 / 12 TRP A  48
HIS A 103
TRP A 193
GLU A 234
LYS A 236
HIS A 270
ASP A 302
ASP A 334
 RNS  A1462 ( 4.1A)
RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 (-2.2A)
RNS  A1462 ( 3.5A)
MN  A 451 ( 2.2A)
RNS  A1462 ( 3.0A)
 0.76A 3ximB-1de6A:
26.8		 3ximB-1de6A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		7 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
HIS A 257
ASP A 289
ASP A 327
 RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
MN  A1004 ( 2.6A)
RNS  A1001 ( 2.8A)
 0.54A 3ximB-4gjiA:
33.7		 3ximB-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		7 / 12 TRP A  48
TRP A 193
GLU A 234
LYS A 236
HIS A 270
ASP A 302
ASP A 334
 RNS  A1462 ( 4.1A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 (-2.2A)
RNS  A1462 ( 3.5A)
MN  A 451 ( 2.2A)
RNS  A1462 ( 3.0A)
 0.61A 3ximC-1de6A:
27.0		 3ximC-1de6A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		7 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
HIS A 257
ASP A 289
ASP A 327
 RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
MN  A1004 ( 2.6A)
RNS  A1001 ( 2.8A)
 0.50A 3ximC-4gjiA:
34.0		 3ximC-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		5 / 12 HIS A 103
TRP A 193
GLU A 234
HIS A 270
ASP A 334
 RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 ( 3.5A)
RNS  A1462 ( 3.0A)
 1.33A 3ximD-1de6A:
26.7		 3ximD-1de6A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		8 / 12 TRP A  48
HIS A 103
TRP A 193
GLU A 234
LYS A 236
HIS A 270
ASP A 302
ASP A 334
 RNS  A1462 ( 4.1A)
RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 (-2.2A)
RNS  A1462 ( 3.5A)
MN  A 451 ( 2.2A)
RNS  A1462 ( 3.0A)
 0.72A 3ximD-1de6A:
26.7		 3ximD-1de6A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		7 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
HIS A 257
ASP A 289
ASP A 327
 RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
MN  A1004 ( 2.6A)
RNS  A1001 ( 2.8A)
 0.49A 3ximD-4gjiA:
33.9		 3ximD-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DVO_A_SORA404_0
(XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		6 / 12 TRP A  48
HIS A 103
TRP A 193
LYS A 236
HIS A 270
ASP A 302
 RNS  A1462 ( 4.1A)
RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
RNS  A1462 (-2.2A)
RNS  A1462 ( 3.5A)
MN  A 451 ( 2.2A)
 0.73A 4dvoA-1de6A:
27.3		 4dvoA-1de6A:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DVO_A_SORA404_0
(XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		6 / 12 TRP A  48
TRP A 193
LYS A 236
ASN A 191
HIS A 270
ASP A 302
 RNS  A1462 ( 4.1A)
RNS  A1462 (-3.2A)
RNS  A1462 (-2.2A)
None
RNS  A1462 ( 3.5A)
MN  A 451 ( 2.2A)
 1.27A 4dvoA-1de6A:
27.3		 4dvoA-1de6A:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DVO_A_SORA404_0
(XYLOSE ISOMERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		5 / 12 TRP A  57
TRP A 179
LYS A 221
HIS A 257
ASP A 289
 RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
MN  A1004 ( 2.6A)
 0.48A 4dvoA-4gjiA:
34.2		 4dvoA-4gjiA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIA_A_SORA400_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		6 / 12 TRP A  48
HIS A 103
TRP A 193
LYS A 236
HIS A 270
ASP A 334
 RNS  A1462 ( 4.1A)
RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
RNS  A1462 (-2.2A)
RNS  A1462 ( 3.5A)
RNS  A1462 ( 3.0A)
 0.65A 4xiaA-1de6A:
26.7		 4xiaA-1de6A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIA_A_SORA400_0
(D-XYLOSE ISOMERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		5 / 12 TRP A  57
TRP A 179
LYS A 221
HIS A 257
ASP A 327
 RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
RNS  A1001 ( 2.8A)
 0.29A 4xiaA-4gjiA:
33.8		 4xiaA-4gjiA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIA_B_SORB400_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		5 / 12 HIS A 103
TRP A 193
GLU A 234
HIS A 270
ASP A 334
 RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 ( 3.5A)
RNS  A1462 ( 3.0A)
 1.28A 4xiaB-1de6A:
10.4		 4xiaB-1de6A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIA_B_SORB400_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		7 / 12 TRP A  48
HIS A 103
TRP A 193
GLU A 234
LYS A 236
HIS A 270
ASP A 334
 RNS  A1462 ( 4.1A)
RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 (-2.2A)
RNS  A1462 ( 3.5A)
RNS  A1462 ( 3.0A)
 0.66A 4xiaB-1de6A:
10.4		 4xiaB-1de6A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIA_B_SORB400_0
(D-XYLOSE ISOMERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		6 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
HIS A 257
ASP A 327
 RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
RNS  A1001 ( 2.8A)
 0.33A 4xiaB-4gjiA:
33.9		 4xiaB-4gjiA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KF8_A_GCSA404_1
(PREDICTED
ACETYLTRANSFERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		4 / 8 TRP A 193
GLU A 234
ASP A 304
TRP A  48
 RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
MN  A 451 (-2.8A)
RNS  A1462 ( 4.1A)
 0.85A 5kf8A-1de6A:
0.0		 5kf8A-1de6A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGJ_A_X6XA402_1
(PREDICTED
ACETYLTRANSFERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		4 / 5 TRP A 193
GLU A 234
ASP A 304
TRP A  48
 RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
MN  A 451 (-2.8A)
RNS  A1462 ( 4.1A)
 0.85A 5kgjA-1de6A:
0.0		 5kgjA-1de6A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		4 / 8 TRP A 193
GLU A 234
ASP A 304
TRP A  48
 RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
MN  A 451 (-2.8A)
RNS  A1462 ( 4.1A)
 0.76A 5kgpA-1de6A:
0.0		 5kgpA-1de6A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		4 / 8 TRP A 179
GLU A 219
ASP A 291
TRP A  57
 RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
MN  A1004 ( 3.9A)
RNS  A1001 (-3.5A)
 1.02A 5kgpA-4gjiA:
undetectable		 5kgpA-4gjiA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		4 / 8 TRP A 193
GLU A 234
ASP A 304
TRP A  48
 RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
MN  A 451 (-2.8A)
RNS  A1462 ( 4.1A)
 0.78A 5kgpB-1de6A:
0.0		 5kgpB-1de6A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		4 / 8 TRP A 179
GLU A 219
ASP A 291
TRP A  57
 RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
MN  A1004 ( 3.9A)
RNS  A1001 (-3.5A)
 1.04A 5kgpB-4gjiA:
undetectable		 5kgpB-4gjiA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM9_B_ADNB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		5 / 12 ILE A 194
LEU A 212
VAL A 233
ALA A 232
HIS A 270
 None
None
None
None
RNS  A1462 ( 3.5A)
 1.03A 5km9B-1de6A:
undetectable		 5km9B-1de6A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_A_SORA503_0
(XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		5 / 9 HIS A 103
TRP A 193
GLU A 234
HIS A 270
ASP A 334
 RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 ( 3.5A)
RNS  A1462 ( 3.0A)
 1.33A 5nhaA-1de6A:
26.3		 5nhaA-1de6A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_A_SORA503_0
(XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		6 / 9 TRP A  48
HIS A 103
TRP A 193
GLU A 234
HIS A 270
ASP A 334
 RNS  A1462 ( 4.1A)
RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 ( 3.5A)
RNS  A1462 ( 3.0A)
 0.68A 5nhaA-1de6A:
26.3		 5nhaA-1de6A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_A_SORA503_0
(XYLOSE ISOMERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		5 / 9 TRP A  57
TRP A 179
GLU A 219
HIS A 257
ASP A 327
 RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
MN  A1004 ( 3.4A)
RNS  A1001 ( 2.8A)
 0.40A 5nhaA-4gjiA:
31.1		 5nhaA-4gjiA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_B_SORB503_0
(XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		5 / 9 HIS A 103
TRP A 193
GLU A 234
HIS A 270
ASP A 334
 RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 ( 3.5A)
RNS  A1462 ( 3.0A)
 1.34A 5nhaB-1de6A:
26.4		 5nhaB-1de6A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_B_SORB503_0
(XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		6 / 9 TRP A  48
HIS A 103
TRP A 193
GLU A 234
HIS A 270
ASP A 334
 RNS  A1462 ( 4.1A)
RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 ( 3.5A)
RNS  A1462 ( 3.0A)
 0.69A 5nhaB-1de6A:
26.4		 5nhaB-1de6A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_B_SORB503_0
(XYLOSE ISOMERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		5 / 9 TRP A  57
TRP A 179
GLU A 219
HIS A 257
ASP A 327
 RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
MN  A1004 ( 3.4A)
RNS  A1001 ( 2.8A)
 0.39A 5nhaB-4gjiA:
31.1		 5nhaB-4gjiA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_C_SORC503_0
(XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		5 / 9 HIS A 103
TRP A 193
GLU A 234
HIS A 270
ASP A 334
 RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 ( 3.5A)
RNS  A1462 ( 3.0A)
 1.33A 5nhaC-1de6A:
26.4		 5nhaC-1de6A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_C_SORC503_0
(XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		6 / 9 TRP A  48
HIS A 103
TRP A 193
GLU A 234
HIS A 270
ASP A 334
 RNS  A1462 ( 4.1A)
RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 ( 3.5A)
RNS  A1462 ( 3.0A)
 0.68A 5nhaC-1de6A:
26.4		 5nhaC-1de6A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_C_SORC503_0
(XYLOSE ISOMERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		5 / 9 TRP A  57
TRP A 179
GLU A 219
HIS A 257
ASP A 327
 RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
MN  A1004 ( 3.4A)
RNS  A1001 ( 2.8A)
 0.39A 5nhaC-4gjiA:
31.1		 5nhaC-4gjiA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_D_SORD503_0
(XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		5 / 9 HIS A 103
TRP A 193
GLU A 234
HIS A 270
ASP A 334
 RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 ( 3.5A)
RNS  A1462 ( 3.0A)
 1.33A 5nhaD-1de6A:
26.4		 5nhaD-1de6A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_D_SORD503_0
(XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		6 / 9 TRP A  48
HIS A 103
TRP A 193
GLU A 234
HIS A 270
ASP A 334
 RNS  A1462 ( 4.1A)
RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 ( 3.5A)
RNS  A1462 ( 3.0A)
 0.68A 5nhaD-1de6A:
26.4		 5nhaD-1de6A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_D_SORD503_0
(XYLOSE ISOMERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		5 / 9 TRP A  57
TRP A 179
GLU A 219
HIS A 257
ASP A 327
 RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
MN  A1004 ( 3.4A)
RNS  A1001 ( 2.8A)
 0.40A 5nhaD-4gjiA:
31.0		 5nhaD-4gjiA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_B_RBFB502_2
(RIBOFLAVIN LYASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		4 / 4 ASN A 283
GLN A 328
ASP A 327
THR A 177
 None
None
RNS  A1001 ( 2.8A)
None
 1.36A 5w4zB-4gjiA:
7.0		 5w4zB-4gjiA:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		5 / 12 HIS A 103
TRP A 193
GLU A 234
HIS A 270
ASP A 334
 RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 ( 3.5A)
RNS  A1462 ( 3.0A)
 1.29A 5ximA-1de6A:
26.8		 5ximA-1de6A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		8 / 12 TRP A  48
HIS A 103
TRP A 193
GLU A 234
LYS A 236
HIS A 270
ASP A 302
ASP A 334
 RNS  A1462 ( 4.1A)
RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 (-2.2A)
RNS  A1462 ( 3.5A)
MN  A 451 ( 2.2A)
RNS  A1462 ( 3.0A)
 0.76A 5ximA-1de6A:
26.8		 5ximA-1de6A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		7 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
HIS A 257
ASP A 289
ASP A 327
 RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
MN  A1004 ( 2.6A)
RNS  A1001 ( 2.8A)
 0.55A 5ximA-4gjiA:
33.9		 5ximA-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		7 / 12 TRP A  48
HIS A 103
TRP A 193
LYS A 236
HIS A 270
ASP A 302
ASP A 334
 RNS  A1462 ( 4.1A)
RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
RNS  A1462 (-2.2A)
RNS  A1462 ( 3.5A)
MN  A 451 ( 2.2A)
RNS  A1462 ( 3.0A)
 0.85A 5ximB-1de6A:
26.8		 5ximB-1de6A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		6 / 12 TRP A  57
TRP A 179
LYS A 221
HIS A 257
ASP A 289
ASP A 327
 RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
MN  A1004 ( 2.6A)
RNS  A1001 ( 2.8A)
 0.63A 5ximB-4gjiA:
33.7		 5ximB-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		5 / 12 HIS A 103
TRP A 193
GLU A 234
HIS A 270
ASP A 334
 RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 ( 3.5A)
RNS  A1462 ( 3.0A)
 1.29A 5ximC-1de6A:
26.8		 5ximC-1de6A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		8 / 12 TRP A  48
HIS A 103
TRP A 193
GLU A 234
LYS A 236
HIS A 270
ASP A 302
ASP A 334
 RNS  A1462 ( 4.1A)
RNS  A1462 (-4.4A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 (-2.2A)
RNS  A1462 ( 3.5A)
MN  A 451 ( 2.2A)
RNS  A1462 ( 3.0A)
 0.82A 5ximC-1de6A:
26.8		 5ximC-1de6A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		7 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
HIS A 257
ASP A 289
ASP A 327
 RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
MN  A1004 ( 2.6A)
RNS  A1001 ( 2.8A)
 0.62A 5ximC-4gjiA:
33.8		 5ximC-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 1de6 L-RHAMNOSE ISOMERASE
(Escherichia
coli) 		7 / 12 TRP A  48
TRP A 193
GLU A 234
LYS A 236
HIS A 270
ASP A 302
ASP A 334
 RNS  A1462 ( 4.1A)
RNS  A1462 (-3.2A)
ZN  A 450 ( 2.4A)
RNS  A1462 (-2.2A)
RNS  A1462 ( 3.5A)
MN  A 451 ( 2.2A)
RNS  A1462 ( 3.0A)
 0.68A 5ximD-1de6A:
26.7		 5ximD-1de6A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 4gji L-RHAMNOSE ISOMERASE
(Pseudomonas
stutzeri) 		7 / 12 TRP A  57
TRP A 179
GLU A 219
LYS A 221
HIS A 257
ASP A 289
ASP A 327
 RNS  A1001 (-3.5A)
RNS  A1001 (-3.3A)
MN  A1003 ( 2.6A)
RNS  A1001 (-2.7A)
MN  A1004 ( 3.4A)
MN  A1004 ( 2.6A)
RNS  A1001 ( 2.8A)
 0.56A 5ximD-4gjiA:
33.6		 5ximD-4gjiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2O_A_8N6A501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1x8d HYPOTHETICAL PROTEIN
YIIL
(Escherichia
coli) 		5 / 12 HIS A  22
LEU A  33
PHE A   6
LEU A  52
TYR A  18
 RNS  A1105 (-3.9A)
None
None
None
RNS  A1105 (-4.5A)
 1.18A 5y2oA-1x8dA:
undetectable		 5y2oA-1x8dA:
20.59