SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'RMO'


List of Similar Pattern of Amino Acids


Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
5 / 10 GLY C1006
HIS C 884
ALA C1079
ILE C1007
GLY C 915
None
None
RMO  C1317 ( 3.6A)
None
None
0.94A 1c9sN-3sr6C:
undetectable
1c9sO-3sr6C:
undetectable
1c9sN-3sr6C:
7.93
1c9sO-3sr6C:
7.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
5 / 11 GLY C1006
HIS C 884
ALA C1079
ILE C1007
GLY C 915
None
None
RMO  C1317 ( 3.6A)
None
None
0.92A 1c9sP-3sr6C:
undetectable
1c9sQ-3sr6C:
undetectable
1c9sP-3sr6C:
7.93
1c9sQ-3sr6C:
7.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
5 / 10 GLY C 915
GLY C1006
HIS C 884
ALA C1079
ILE C1007
None
None
None
RMO  C1317 ( 3.6A)
None
0.93A 1c9sL-3sr6C:
undetectable
1c9sV-3sr6C:
undetectable
1c9sL-3sr6C:
7.93
1c9sV-3sr6C:
7.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FO4_A_SALA3005_1
(XANTHINE
DEHYDROGENASE)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
9 / 9 GLU C 802
LEU C 873
SER C 876
ARG C 880
PHE C 914
THR C1010
VAL C1011
LEU C1014
ALA C1079
RMO  C1317 (-4.4A)
None
None
None
RMO  C1317 (-3.6A)
None
None
None
RMO  C1317 ( 3.6A)
0.31A 1fo4A-3sr6C:
52.6
1fo4A-3sr6C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FO4_A_SALA3005_1
(XANTHINE
DEHYDROGENASE)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
5 / 9 SER C 876
PHE C 914
VAL C1011
LEU C1014
ALA C1078
None
RMO  C1317 (-3.6A)
None
None
RMO  C1317 (-3.2A)
1.20A 1fo4A-3sr6C:
52.6
1fo4A-3sr6C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FO4_B_SALB4005_1
(XANTHINE
DEHYDROGENASE)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
7 / 7 GLU C 802
SER C 876
ARG C 880
PHE C 914
THR C1010
VAL C1011
ALA C1078
RMO  C1317 (-4.4A)
None
None
RMO  C1317 (-3.6A)
None
None
RMO  C1317 (-3.2A)
0.24A 1fo4B-3sr6C:
41.7
1fo4B-3sr6C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FO4_B_SALB4005_1
(XANTHINE
DEHYDROGENASE)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
4 / 7 SER C 876
PHE C 914
VAL C1011
ALA C1079
None
RMO  C1317 (-3.6A)
None
RMO  C1317 ( 3.6A)
0.98A 1fo4B-3sr6C:
41.7
1fo4B-3sr6C:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
5 / 11 GLY C1006
HIS C 884
ALA C1079
ILE C1007
GLY C 915
None
None
RMO  C1317 ( 3.6A)
None
None
0.94A 1gtfQ-3sr6C:
undetectable
1gtfR-3sr6C:
undetectable
1gtfQ-3sr6C:
7.93
1gtfR-3sr6C:
7.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
5 / 11 GLY C1006
HIS C 884
ALA C1079
ILE C1007
GLY C 915
None
None
RMO  C1317 ( 3.6A)
None
None
0.93A 1gtfS-3sr6C:
undetectable
1gtfT-3sr6C:
undetectable
1gtfS-3sr6C:
7.93
1gtfT-3sr6C:
7.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
5 / 11 GLY C1006
HIS C 884
ALA C1079
ILE C1007
GLY C 915
None
None
RMO  C1317 ( 3.6A)
None
None
0.94A 1gtnT-3sr6C:
undetectable
1gtnU-3sr6C:
undetectable
1gtnT-3sr6C:
7.93
1gtnU-3sr6C:
7.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
5 / 12 GLY C 915
GLY C1006
HIS C 884
ALA C1079
ILE C1007
None
None
None
RMO  C1317 ( 3.6A)
None
0.95A 1gtnL-3sr6C:
undetectable
1gtnV-3sr6C:
undetectable
1gtnL-3sr6C:
7.93
1gtnV-3sr6C:
7.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
11 / 12 LEU C 648
ASN C 768
GLU C 802
LEU C 873
SER C 876
ARG C 880
PHE C 914
THR C1010
VAL C1011
ALA C1078
ALA C1079
None
None
RMO  C1317 (-4.4A)
None
None
None
RMO  C1317 (-3.6A)
None
None
RMO  C1317 (-3.2A)
RMO  C1317 ( 3.6A)
0.35A 1n5xA-3sr6C:
65.9
1n5xA-3sr6C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
10 / 12 LEU C 648
LYS C 771
GLU C 802
LEU C 873
SER C 876
ARG C 880
PHE C 914
THR C1010
VAL C1011
ALA C1079
None
None
RMO  C1317 (-4.4A)
None
None
None
RMO  C1317 (-3.6A)
None
None
RMO  C1317 ( 3.6A)
0.77A 1n5xA-3sr6C:
65.9
1n5xA-3sr6C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
5 / 12 LEU C 873
SER C 876
PHE C 914
VAL C1011
ALA C1079
None
None
RMO  C1317 (-3.6A)
None
RMO  C1317 ( 3.6A)
1.11A 1n5xA-3sr6C:
65.9
1n5xA-3sr6C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
11 / 12 LEU C 648
ASN C 768
GLU C 802
LEU C 873
SER C 876
ARG C 880
PHE C 914
THR C1010
VAL C1011
ALA C1078
ALA C1079
None
None
RMO  C1317 (-4.4A)
None
None
None
RMO  C1317 (-3.6A)
None
None
RMO  C1317 (-3.2A)
RMO  C1317 ( 3.6A)
0.35A 1n5xB-3sr6C:
65.9
1n5xB-3sr6C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
10 / 12 LEU C 648
LYS C 771
GLU C 802
LEU C 873
SER C 876
ARG C 880
PHE C 914
THR C1010
VAL C1011
ALA C1079
None
None
RMO  C1317 (-4.4A)
None
None
None
RMO  C1317 (-3.6A)
None
None
RMO  C1317 ( 3.6A)
0.77A 1n5xB-3sr6C:
65.9
1n5xB-3sr6C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
5 / 12 LEU C 873
SER C 876
PHE C 914
VAL C1011
ALA C1079
None
None
RMO  C1317 (-3.6A)
None
RMO  C1317 ( 3.6A)
1.11A 1n5xB-3sr6C:
65.9
1n5xB-3sr6C:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
5 / 12 GLY C1006
HIS C 884
ALA C1079
ILE C1007
GLY C 915
None
None
RMO  C1317 ( 3.6A)
None
None
0.95A 1utdO-3sr6C:
undetectable
1utdP-3sr6C:
undetectable
1utdO-3sr6C:
7.93
1utdP-3sr6C:
7.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
5 / 11 GLY C1006
HIS C 884
ALA C1079
ILE C1007
GLY C 915
None
None
RMO  C1317 ( 3.6A)
None
None
0.95A 1utdP-3sr6C:
undetectable
1utdQ-3sr6C:
undetectable
1utdP-3sr6C:
7.93
1utdQ-3sr6C:
7.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
5 / 11 GLY C1006
HIS C 884
ALA C1079
ILE C1007
GLY C 915
None
None
RMO  C1317 ( 3.6A)
None
None
0.92A 1utdS-3sr6C:
undetectable
1utdT-3sr6C:
undetectable
1utdS-3sr6C:
7.93
1utdT-3sr6C:
7.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
5 / 10 GLY C1006
HIS C 884
ALA C1079
ILE C1007
GLY C 915
None
None
RMO  C1317 ( 3.6A)
None
None
0.96A 1utdU-3sr6C:
undetectable
1utdV-3sr6C:
undetectable
1utdU-3sr6C:
7.93
1utdV-3sr6C:
7.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WYG_A_SALA4005_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
9 / 10 GLU C 802
LEU C 873
ARG C 880
PHE C 914
PHE C1009
THR C1010
ALA C1078
ALA C1079
GLU C1261
RMO  C1317 (-4.4A)
None
None
RMO  C1317 (-3.6A)
None
None
RMO  C1317 (-3.2A)
RMO  C1317 ( 3.6A)
RMO  C1317 (-3.4A)
0.38A 1wygA-3sr6C:
55.3
1wygA-3sr6C:
59.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WYG_A_SALA4005_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
9 / 10 GLU C 802
LEU C 873
SER C 876
ARG C 880
PHE C 914
PHE C1009
ALA C1078
ALA C1079
GLU C1261
RMO  C1317 (-4.4A)
None
None
None
RMO  C1317 (-3.6A)
None
RMO  C1317 (-3.2A)
RMO  C1317 ( 3.6A)
RMO  C1317 (-3.4A)
0.35A 1wygA-3sr6C:
55.3
1wygA-3sr6C:
59.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
6 / 6 ARG C 880
PHE C 914
THR C1010
VAL C1011
LEU C1014
ALA C1079
None
RMO  C1317 (-3.6A)
None
None
None
RMO  C1317 ( 3.6A)
0.40A 2e1qA-3sr6C:
53.4
2e1qA-3sr6C:
61.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2E1Q_B_SALB3006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
4 / 4 ARG C 880
PHE C 914
THR C1010
ALA C1079
None
RMO  C1317 (-3.6A)
None
RMO  C1317 ( 3.6A)
0.34A 2e1qB-3sr6C:
53.5
2e1qB-3sr6C:
61.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
6 / 6 ARG C 880
PHE C 914
THR C1010
VAL C1011
LEU C1014
ALA C1079
None
RMO  C1317 (-3.6A)
None
None
None
RMO  C1317 ( 3.6A)
0.34A 2e1qC-3sr6C:
64.8
2e1qC-3sr6C:
61.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2E1Q_D_SALD5006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
5 / 5 ARG C 880
PHE C 914
THR C1010
LEU C1014
ALA C1079
None
RMO  C1317 (-3.6A)
None
None
RMO  C1317 ( 3.6A)
0.35A 2e1qD-3sr6C:
62.3
2e1qD-3sr6C:
61.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_B_CTCB1385_0
(TETX2 PROTEIN)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
4 / 8 GLN C 918
PHE C 914
GLY C 915
GLY C 800
None
RMO  C1317 (-3.6A)
None
None
0.85A 2y6rB-3sr6C:
undetectable
2y6rB-3sr6C:
19.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
8 / 8 GLU C 802
SER C 876
ARG C 880
PHE C 914
THR C1010
VAL C1011
LEU C1014
ALA C1079
RMO  C1317 (-4.4A)
None
None
RMO  C1317 (-3.6A)
None
None
None
RMO  C1317 ( 3.6A)
0.17A 3ax7A-3sr6C:
61.6
3ax7A-3sr6C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
5 / 8 SER C 876
PHE C 914
VAL C1011
LEU C1014
ALA C1078
None
RMO  C1317 (-3.6A)
None
None
RMO  C1317 (-3.2A)
1.11A 3ax7A-3sr6C:
61.6
3ax7A-3sr6C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AX7_B_SALB1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
9 / 9 GLU C 802
SER C 876
ARG C 880
PHE C 914
THR C1010
VAL C1011
LEU C1014
ALA C1078
ALA C1079
RMO  C1317 (-4.4A)
None
None
RMO  C1317 (-3.6A)
None
None
None
RMO  C1317 (-3.2A)
RMO  C1317 ( 3.6A)
0.24A 3ax7B-3sr6C:
63.0
3ax7B-3sr6C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
8 / 8 GLU C 802
LEU C 873
SER C 876
ARG C 880
PHE C 914
THR C1010
ALA C1078
ALA C1079
RMO  C1317 (-4.4A)
None
None
None
RMO  C1317 (-3.6A)
None
RMO  C1317 (-3.2A)
RMO  C1317 ( 3.6A)
0.24A 3ax9B-3sr6C:
66.1
3ax9B-3sr6C:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN Q5LES9)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
5 / 12 GLN C 767
GLY C 795
GLY C 797
LEU C 744
GLU C1037
RMO  C1317 (-3.6A)
None
MTE  C1316 (-3.5A)
None
None
1.09A 3kkzA-3sr6C:
undetectable
3kkzA-3sr6C:
16.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NS1_C_PM6C1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
6 / 6 GLU C 802
ARG C 880
PHE C 914
THR C1010
ALA C1078
ALA C1079
RMO  C1317 (-4.4A)
None
RMO  C1317 (-3.6A)
None
RMO  C1317 (-3.2A)
RMO  C1317 ( 3.6A)
0.25A 3ns1C-3sr6C:
67.2
3ns1C-3sr6C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NS1_L_PM6L1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
8 / 8 GLU C 802
SER C 876
ARG C 880
PHE C 914
THR C1010
LEU C1014
ALA C1078
ALA C1079
RMO  C1317 (-4.4A)
None
None
RMO  C1317 (-3.6A)
None
None
RMO  C1317 (-3.2A)
RMO  C1317 ( 3.6A)
0.23A 3ns1L-3sr6C:
57.6
3ns1L-3sr6C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UNA_A_SALA1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
9 / 9 GLU C 802
LEU C 873
SER C 876
ARG C 880
PHE C 914
THR C1010
VAL C1011
LEU C1014
ALA C1079
RMO  C1317 (-4.4A)
None
None
None
RMO  C1317 (-3.6A)
None
None
None
RMO  C1317 ( 3.6A)
0.24A 3unaA-3sr6C:
67.3
3unaA-3sr6C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UNA_A_SALA1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
5 / 9 SER C 876
PHE C 914
VAL C1011
LEU C1014
ALA C1078
None
RMO  C1317 (-3.6A)
None
None
RMO  C1317 (-3.2A)
1.20A 3unaA-3sr6C:
67.3
3unaA-3sr6C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UNA_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
9 / 9 GLU C 802
LEU C 873
SER C 876
ARG C 880
PHE C 914
THR C1010
VAL C1011
LEU C1014
ALA C1079
RMO  C1317 (-4.4A)
None
None
None
RMO  C1317 (-3.6A)
None
None
None
RMO  C1317 ( 3.6A)
0.22A 3unaB-3sr6C:
61.3
3unaB-3sr6C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UNA_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
5 / 9 SER C 876
PHE C 914
VAL C1011
LEU C1014
ALA C1078
None
RMO  C1317 (-3.6A)
None
None
RMO  C1317 (-3.2A)
1.18A 3unaB-3sr6C:
61.3
3unaB-3sr6C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UNC_A_SALA1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
9 / 9 GLU C 802
LEU C 873
SER C 876
ARG C 880
PHE C 914
THR C1010
VAL C1011
LEU C1014
ALA C1079
RMO  C1317 (-4.4A)
None
None
None
RMO  C1317 (-3.6A)
None
None
None
RMO  C1317 ( 3.6A)
0.21A 3uncA-3sr6C:
65.7
3uncA-3sr6C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UNC_A_SALA1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
5 / 9 SER C 876
PHE C 914
VAL C1011
LEU C1014
ALA C1078
None
RMO  C1317 (-3.6A)
None
None
RMO  C1317 (-3.2A)
1.16A 3uncA-3sr6C:
65.7
3uncA-3sr6C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UNC_B_SALB1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
9 / 9 GLU C 802
LEU C 873
SER C 876
ARG C 880
PHE C 914
THR C1010
VAL C1011
LEU C1014
ALA C1079
RMO  C1317 (-4.4A)
None
None
None
RMO  C1317 (-3.6A)
None
None
None
RMO  C1317 ( 3.6A)
0.22A 3uncB-3sr6C:
56.8
3uncB-3sr6C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UNC_B_SALB1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
5 / 9 SER C 876
PHE C 914
VAL C1011
LEU C1014
ALA C1078
None
RMO  C1317 (-3.6A)
None
None
RMO  C1317 (-3.2A)
1.16A 3uncB-3sr6C:
56.8
3uncB-3sr6C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
7 / 7 GLU C 802
ARG C 880
PHE C 914
THR C1010
VAL C1011
LEU C1014
ALA C1079
RMO  C1317 (-4.4A)
None
RMO  C1317 (-3.6A)
None
None
None
RMO  C1317 ( 3.6A)
0.23A 3uniA-3sr6C:
61.3
3uniA-3sr6C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
8 / 8 GLU C 802
LEU C 873
ARG C 880
PHE C 914
THR C1010
VAL C1011
LEU C1014
ALA C1079
RMO  C1317 (-4.4A)
None
None
RMO  C1317 (-3.6A)
None
None
None
RMO  C1317 ( 3.6A)
0.24A 3uniB-3sr6C:
69.6
3uniB-3sr6C:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
4 / 8 GLN C 918
PHE C 914
GLY C 915
GLY C 800
None
RMO  C1317 (-3.6A)
None
None
0.80A 3v3nB-3sr6C:
undetectable
3v3nB-3sr6C:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
4 / 8 GLN C 918
PHE C 914
GLY C 915
GLY C 800
None
RMO  C1317 (-3.6A)
None
None
0.79A 3v3nC-3sr6C:
undetectable
3v3nC-3sr6C:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
5 / 12 ALA C1258
GLY C1006
GLU C 802
ALA C 910
GLY C 913
None
None
RMO  C1317 (-4.4A)
RMO  C1317 ( 4.0A)
None
1.05A 4r29B-3sr6C:
undetectable
4r29B-3sr6C:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_1
(PROTEIN CYP51)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
5 / 12 PHE C1013
PHE C1009
ALA C1079
THR C 803
LEU C 648
None
None
RMO  C1317 ( 3.6A)
None
None
1.13A 5tl8A-3sr6C:
undetectable
5tl8A-3sr6C:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYB_A_KKKA508_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
5 / 12 PHE C1013
PHE C1009
ALA C1079
THR C 803
LEU C 648
None
None
RMO  C1317 ( 3.6A)
None
None
1.21A 6aybA-3sr6C:
undetectable
6aybA-3sr6C:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_1
(PROTEIN CYP51)
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos
taurus)
5 / 12 PHE C1013
PHE C1009
ALA C1079
THR C 803
LEU C 648
None
None
RMO  C1317 ( 3.6A)
None
None
1.12A 6aycA-3sr6C:
undetectable
6aycA-3sr6C:
8.45