SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'RCJ'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BWL_C_MN9C1297_0
(N-ACETYLNEURAMINATE
LYASE)		 5kzd N-ACETYLNEURAMINATE
LYASE
(Staphylococcus
aureus) 		5 / 10 GLY A 189
ASP A 191
GLU A 192
GLY A 207
SER A 208
 RCJ  A 301 (-3.6A)
RCJ  A 301 (-2.5A)
RCJ  A 301 (-3.1A)
RCJ  A 301 (-3.2A)
RCJ  A 301 (-3.2A)
 0.37A 4bwlC-5kzdA:
39.4		 4bwlC-5kzdA:
36.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_C_MTXC603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 5kzd N-ACETYLNEURAMINATE
LYASE
(Staphylococcus
aureus) 		5 / 12 ALA A  10
LEU A 255
SER A 239
ILE A 243
LEU A 247
 None
None
None
RCJ  A 301 (-4.6A)
RCJ  A 301 ( 4.7A)
 1.10A 4ky8C-5kzdA:
undetectable		 4ky8C-5kzdA:
20.72