SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'RBL'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6001_0
(PANTOTHENATE KINASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 11 ASN A  88
VAL B 110
GLY B 107
ASP B  87
ILE B  69
 None
None
None
None
RBL  B 201 ( 4.7A)
 1.13A 2f9wA-4lfnA:
undetectable
2f9wB-4lfnA:
undetectable		 2f9wA-4lfnA:
28.47
2f9wB-4lfnA:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 11 ASN A  88
VAL B 110
GLY B 107
ASP B  87
ILE B  69
 None
None
None
None
RBL  B 201 ( 4.7A)
 1.19A 3bexC-4lfnA:
undetectable
3bexD-4lfnA:
undetectable		 3bexC-4lfnA:
22.31
3bexD-4lfnA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 10 ASN A  88
VAL B 110
GLY B 107
ASP B  87
ILE B  69
 None
None
None
None
RBL  B 201 ( 4.7A)
 1.19A 3bexC-4lfnA:
undetectable
3bexD-4lfnA:
undetectable		 3bexC-4lfnA:
22.31
3bexD-4lfnA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 10 ASN A  88
VAL B 110
GLY B 107
ASP B  87
ILE B  69
 None
None
None
None
RBL  B 201 ( 4.7A)
 1.19A 3bexE-4lfnA:
undetectable
3bexF-4lfnA:
undetectable		 3bexE-4lfnA:
22.31
3bexF-4lfnA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 11 ASN A  88
VAL B 110
GLY B 107
ASP B  87
ILE B  69
 None
None
None
None
RBL  B 201 ( 4.7A)
 1.18A 3bexE-4lfnA:
undetectable
3bexF-4lfnA:
undetectable		 3bexE-4lfnA:
22.31
3bexF-4lfnA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 11 ASN A  88
VAL B 110
GLY B 107
ASP B  87
ILE B  69
 None
None
None
None
RBL  B 201 ( 4.7A)
 1.16A 3bf1A-4lfnA:
undetectable
3bf1B-4lfnA:
undetectable		 3bf1A-4lfnA:
22.31
3bf1B-4lfnA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 12 ASN A  88
VAL B 110
GLY B 107
ASP B  87
ILE B  69
 None
None
None
None
RBL  B 201 ( 4.7A)
 1.15A 3bf1A-4lfnA:
undetectable
3bf1B-4lfnA:
undetectable		 3bf1A-4lfnA:
22.31
3bf1B-4lfnA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 11 ASN A  88
VAL B 110
GLY B 107
ASP B  87
ILE B  69
 None
None
None
None
RBL  B 201 ( 4.7A)
 1.17A 3bf1C-4lfnA:
undetectable
3bf1D-4lfnA:
undetectable		 3bf1C-4lfnA:
22.31
3bf1D-4lfnA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 11 ASN A  88
VAL B 110
GLY B 107
ASP B  87
ILE B  69
 None
None
None
None
RBL  B 201 ( 4.7A)
 1.16A 3bf1C-4lfnA:
undetectable
3bf1D-4lfnA:
undetectable		 3bf1C-4lfnA:
22.31
3bf1D-4lfnA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 11 ASN A  88
VAL B 110
GLY B 107
ASP B  87
ILE B  69
 None
None
None
None
RBL  B 201 ( 4.7A)
 1.20A 3bf1E-4lfnA:
undetectable
3bf1F-4lfnA:
undetectable		 3bf1E-4lfnA:
22.31
3bf1F-4lfnA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 11 ASN A  88
VAL B 110
GLY B 107
ASP B  87
ILE B  69
 None
None
None
None
RBL  B 201 ( 4.7A)
 1.16A 3bf1E-4lfnA:
undetectable
3bf1F-4lfnA:
undetectable		 3bf1E-4lfnA:
22.31
3bf1F-4lfnA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_A_ACTA401_0
(UNCHARACTERIZED
PROTEIN)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus) 		5 / 9 GLY B 107
ASP B   8
CYH B  65
GLY B  68
THR B  67
 None
RBL  B 201 (-3.0A)
RBL  B 201 (-3.4A)
None
RBL  B 201 (-3.4A)
 1.38A 4lb0A-4lfnB:
undetectable		 4lb0A-4lfnB:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus) 		5 / 12 ASP B  87
THR A  81
ALA A  99
ASN A  97
CYH B  65
 None
None
None
RBL  B 201 (-2.7A)
RBL  B 201 (-3.4A)
 1.34A 4u15B-4lfnB:
undetectable		 4u15B-4lfnB:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_A_SAMA1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus) 		5 / 12 GLY B 105
TYR B  42
TYR B 123
ALA B  92
ALA B  84
 None
RBL  B 201 (-4.1A)
None
None
None
 1.27A 4ymgA-4lfnB:
undetectable		 4ymgA-4lfnB:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus) 		5 / 12 GLY B 105
TYR B  42
TYR B 123
ALA B  92
ALA B  84
 None
RBL  B 201 (-4.1A)
None
None
None
 1.29A 4ymgB-4lfnB:
undetectable		 4ymgB-4lfnB:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_D_ILED602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 6 ILE B  69
ALA A  90
THR A  89
VAL A  84
HIS A  91
 RBL  B 201 ( 4.7A)
None
None
None
None
 1.23A 5eclD-4lfnB:
undetectable		 5eclD-4lfnB:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_C_PFLC407_1
(PROTON-GATED ION
CHANNEL)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus) 		5 / 9 TYR B  42
PRO B  43
ILE A 133
TRP B 165
TYR B  45
 RBL  B 201 (-4.1A)
None
None
None
None
 1.19A 5mvnC-4lfnB:
undetectable		 5mvnC-4lfnB:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus) 		5 / 10 TYR B  42
PRO B  43
ILE A 133
TRP B 165
TYR B  45
 RBL  B 201 (-4.1A)
None
None
None
None
 1.20A 5mvnD-4lfnB:
undetectable		 5mvnD-4lfnB:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 12 GLY B  46
GLY B  66
THR B  67
HIS A  96
ILE B  10
 None
RBL  B 201 (-3.4A)
RBL  B 201 (-3.4A)
RBL  B 201 (-3.7A)
RBL  B 201 (-4.1A)
 0.94A 5wz1A-4lfnB:
undetectable		 5wz1A-4lfnB:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 12 GLY B  46
GLY B  66
THR B  67
HIS A  96
ILE B  10
 None
RBL  B 201 (-3.4A)
RBL  B 201 (-3.4A)
RBL  B 201 (-3.7A)
RBL  B 201 (-4.1A)
 0.93A 5wz1C-4lfnB:
undetectable		 5wz1C-4lfnB:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 12 GLY B  46
GLY B  66
THR B  67
HIS A  96
ILE B  10
 None
RBL  B 201 (-3.4A)
RBL  B 201 (-3.4A)
RBL  B 201 (-3.7A)
RBL  B 201 (-4.1A)
 0.91A 5wz1D-4lfnB:
undetectable		 5wz1D-4lfnB:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 12 GLY B  46
GLY B  66
THR B  67
HIS A  96
ILE B  10
 None
RBL  B 201 (-3.4A)
RBL  B 201 (-3.4A)
RBL  B 201 (-3.7A)
RBL  B 201 (-4.1A)
 0.95A 5wz1E-4lfnB:
undetectable		 5wz1E-4lfnB:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 12 GLY B  46
GLY B  66
THR B  67
HIS A  96
ILE B  10
 None
RBL  B 201 (-3.4A)
RBL  B 201 (-3.4A)
RBL  B 201 (-3.7A)
RBL  B 201 (-4.1A)
 0.92A 5wz1F-4lfnB:
undetectable		 5wz1F-4lfnB:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 12 GLY B  46
GLY B  66
THR B  67
HIS A  96
ILE B  10
 None
RBL  B 201 (-3.4A)
RBL  B 201 (-3.4A)
RBL  B 201 (-3.7A)
RBL  B 201 (-4.1A)
 0.92A 5wz1G-4lfnB:
undetectable		 5wz1G-4lfnB:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 12 GLY B  46
GLY B  66
THR B  67
HIS A  96
ILE B  10
 None
RBL  B 201 (-3.4A)
RBL  B 201 (-3.4A)
RBL  B 201 (-3.7A)
RBL  B 201 (-4.1A)
 0.95A 5wz1H-4lfnB:
undetectable		 5wz1H-4lfnB:
19.06