SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'RBF'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))		 4iil MEMBRANE LIPOPROTEIN
TPN38(B)
(Treponema
pallidum) 		5 / 12 VAL A  26
GLN A 121
ILE A 164
GLY A 154
ILE A 213
 RBF  A 401 (-3.9A)
RBF  A 401 (-3.3A)
RBF  A 401 ( 4.7A)
None
RBF  A 401 (-3.7A)
 0.89A 1bx4A-4iilA:
4.9		 1bx4A-4iilA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 1hze RIBOFLAVIN SYNTHASE
ALPHA CHAIN
(Escherichia
coli) 		4 / 5 THR A  71
THR A  67
THR A  50
HIS A  44
 None
RBF  A  98 (-3.1A)
None
None
 1.34A 1d4fB-1hzeA:
undetectable		 1d4fB-1hzeA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3ddy LUMAZINE PROTEIN
(Photobacterium
leiognathi) 		4 / 4 ILE A  63
LEU A  83
VAL A  81
ILE A  12
 RBF  A 187 ( 4.6A)
None
None
None
 0.89A 1fm6D-3ddyA:
undetectable		 1fm6D-3ddyA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 5w4z RIBOFLAVIN LYASE
(Herbiconiux) 		4 / 7 PHE A 248
SER A 232
SER A  22
PHE A  14
 9WY  A 501 (-3.4A)
9WY  A 501 (-3.6A)
RBF  A 502 (-3.8A)
RBF  A 502 (-3.6A)
 1.14A 1fxvA-5w4zA:
undetectable
1fxvB-5w4zA:
undetectable		 1fxvA-5w4zA:
undetectable
1fxvB-5w4zA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I18_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 1hze RIBOFLAVIN SYNTHASE
ALPHA CHAIN
(Escherichia
coli) 		7 / 10 CYH A  48
LEU A  49
ASP A  62
LEU A  63
THR A  67
ILE A  70
THR A  71
 RBF  A  98 (-3.3A)
RBF  A  98 (-3.8A)
RBF  A  98 (-2.7A)
RBF  A  98 (-4.1A)
RBF  A  98 (-3.1A)
RBF  A  98 ( 4.1A)
None
 0.23A 1i18A-1hzeA:
20.4
1i18B-1hzeA:
20.2		 1i18A-1hzeA:
100.00
1i18B-1hzeA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I18_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 1hze RIBOFLAVIN SYNTHASE
ALPHA CHAIN
(Escherichia
coli) 		7 / 10 CYH A  48
LEU A  49
ASP A  62
LEU A  63
THR A  67
ILE A  70
THR A  71
 RBF  A  98 (-3.3A)
RBF  A  98 (-3.8A)
RBF  A  98 (-2.7A)
RBF  A  98 (-4.1A)
RBF  A  98 (-3.1A)
RBF  A  98 ( 4.1A)
None
 0.23A 1i18A-1hzeA:
20.4
1i18B-1hzeA:
20.2		 1i18A-1hzeA:
100.00
1i18B-1hzeA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_B_AG2B7011_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 4e0f RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA
(Brucella
abortus) 		4 / 5 GLU A  70
ARG A 192
LEU A  74
ASP A 108
 None
None
RBF  A 301 ( 4.8A)
None
 1.28A 1n13B-4e0fA:
undetectable
1n13C-4e0fA:
undetectable		 1n13B-4e0fA:
23.76
1n13C-4e0fA:
17.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PKV_A_RBFA100_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 1hze RIBOFLAVIN SYNTHASE
ALPHA CHAIN
(Escherichia
coli) 		5 / 11 CYH A  47
CYH A  48
LEU A  49
THR A  50
THR A  71
 None
RBF  A  98 (-3.3A)
RBF  A  98 (-3.8A)
None
None
 1.24A 1pkvA-1hzeA:
13.9
1pkvB-1hzeA:
13.7		 1pkvA-1hzeA:
100.00
1pkvB-1hzeA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PKV_A_RBFA100_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 1hze RIBOFLAVIN SYNTHASE
ALPHA CHAIN
(Escherichia
coli) 		5 / 11 CYH A  48
LEU A  49
THR A  50
ILE A  70
THR A  71
 RBF  A  98 (-3.3A)
RBF  A  98 (-3.8A)
None
RBF  A  98 ( 4.1A)
None
 1.14A 1pkvA-1hzeA:
13.9
1pkvB-1hzeA:
13.7		 1pkvA-1hzeA:
100.00
1pkvB-1hzeA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PKV_A_RBFA100_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 1hze RIBOFLAVIN SYNTHASE
ALPHA CHAIN
(Escherichia
coli) 		5 / 11 SER A  41
CYH A  47
LEU A  49
THR A  50
THR A  71
 None
None
RBF  A  98 (-3.8A)
None
None
 1.04A 1pkvA-1hzeA:
13.9
1pkvB-1hzeA:
13.7		 1pkvA-1hzeA:
100.00
1pkvB-1hzeA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_A_RBFA100_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 4e0f RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA
(Brucella
abortus) 		6 / 11 SER A  40
CYH A  47
LEU A  48
THR A  49
THR A  75
VAL A 107
 RBF  A 301 (-3.3A)
RBF  A 301 (-3.4A)
RBF  A 301 (-4.4A)
RBF  A 301 (-3.9A)
None
RBF  A 301 (-3.9A)
 0.30A 1pkvA-4e0fA:
14.9
1pkvB-4e0fA:
15.1		 1pkvA-4e0fA:
24.29
1pkvB-4e0fA:
24.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PKV_B_RBFB101_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 1hze RIBOFLAVIN SYNTHASE
ALPHA CHAIN
(Escherichia
coli) 		5 / 11 CYH A  47
CYH A  48
LEU A  49
THR A  50
THR A  71
 None
RBF  A  98 (-3.3A)
RBF  A  98 (-3.8A)
None
None
 1.19A 1pkvA-1hzeA:
13.9
1pkvB-1hzeA:
13.7		 1pkvA-1hzeA:
100.00
1pkvB-1hzeA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PKV_B_RBFB101_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 1hze RIBOFLAVIN SYNTHASE
ALPHA CHAIN
(Escherichia
coli) 		5 / 11 CYH A  48
LEU A  49
THR A  50
ILE A  70
THR A  71
 RBF  A  98 (-3.3A)
RBF  A  98 (-3.8A)
None
RBF  A  98 ( 4.1A)
None
 1.11A 1pkvA-1hzeA:
13.9
1pkvB-1hzeA:
13.7		 1pkvA-1hzeA:
100.00
1pkvB-1hzeA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PKV_B_RBFB101_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 1hze RIBOFLAVIN SYNTHASE
ALPHA CHAIN
(Escherichia
coli) 		5 / 11 SER A  41
CYH A  47
LEU A  49
THR A  50
THR A  71
 None
None
RBF  A  98 (-3.8A)
None
None
 1.03A 1pkvA-1hzeA:
13.9
1pkvB-1hzeA:
13.7		 1pkvA-1hzeA:
100.00
1pkvB-1hzeA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_B_RBFB101_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 4e0f RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA
(Brucella
abortus) 		6 / 11 VAL A 107
SER A  40
CYH A  47
LEU A  48
THR A  49
THR A  75
 RBF  A 301 (-3.9A)
RBF  A 301 (-3.3A)
RBF  A 301 (-3.4A)
RBF  A 301 (-4.4A)
RBF  A 301 (-3.9A)
None
 0.28A 1pkvA-4e0fA:
14.9
1pkvB-4e0fA:
15.1		 1pkvA-4e0fA:
24.29
1pkvB-4e0fA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UHO_A_VDNA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5kbw RIBOFLAVIN
TRANSPORTER RIBU
(Thermotoga
maritima) 		5 / 10 ALA A 115
PHE A 118
LEU A 122
MET A  79
GLY A  76
 None
None
None
RBF  A 201 (-3.5A)
RBF  A 201 (-2.9A)
 1.50A 1uhoA-5kbwA:
undetectable		 1uhoA-5kbwA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4e0f RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA
(Brucella
abortus) 		6 / 10 LEU A  88
ALA A  42
ILE A  41
ALA A  67
LEU A  23
PHE A  63
 None
None
None
RBF  A 301 (-4.1A)
None
None
 1.48A 1xp0A-4e0fA:
undetectable		 1xp0A-4e0fA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4p6v NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT A
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT B
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT E
(Vibrio
cholerae;
Vibrio
cholerae;
Vibrio
cholerae) 		5 / 12 TYR E 166
ASP B 397
VAL B 401
HIS B 398
ALA A 410
 None
None
None
RBF  E 201 ( 4.9A)
None
 1.23A 2g70A-4p6vE:
undetectable		 2g70A-4p6vE:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4p6v NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT A
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT B
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT E
(Vibrio
cholerae;
Vibrio
cholerae;
Vibrio
cholerae) 		5 / 12 TYR E 166
ASP B 397
VAL B 401
HIS B 398
ALA A 410
 None
None
None
RBF  E 201 ( 4.9A)
None
 1.29A 2g70B-4p6vE:
undetectable		 2g70B-4p6vE:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEO_A_LNRA200_1
(D7R4 PROTEIN)		 4p6v NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT A
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT B
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT E
(Vibrio
cholerae) 		5 / 12 GLU B 402
TYR E 166
HIS B 398
VAL E  35
ASP A 401
 RBF  E 201 (-4.8A)
None
RBF  E 201 ( 4.9A)
None
None
 1.48A 2qeoA-4p6vB:
undetectable		 2qeoA-4p6vB:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA503_0
(CHORISMATE SYNTHASE)		 5w4z RIBOFLAVIN LYASE
(Herbiconiux) 		4 / 5 GLN A 343
THR A 342
ARG A 346
ALA A 345
 RBF  A 502 (-4.1A)
9WY  A 501 (-3.7A)
None
None
 1.28A 2qhfA-5w4zA:
undetectable		 2qhfA-5w4zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 1hze RIBOFLAVIN SYNTHASE
ALPHA CHAIN
(Escherichia
coli) 		4 / 8 ILE A  70
ASP A  75
LEU A  73
GLY A  74
 RBF  A  98 ( 4.1A)
None
None
None
 0.96A 2tsrB-1hzeA:
undetectable		 2tsrB-1hzeA:
15.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 3ddy LUMAZINE PROTEIN
(Photobacterium
leiognathi) 		6 / 12 CYH A  47
ASP A  64
GLN A  65
ALA A  66
ASN A 101
ILE A 102
 RBF  A 187 (-3.3A)
RBF  A 187 (-4.4A)
RBF  A 187 (-3.7A)
RBF  A 187 (-3.1A)
RBF  A 187 (-3.7A)
RBF  A 187 (-4.4A)
 0.87A 3a35A-3ddyA:
29.7		 3a35A-3ddyA:
55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 3ddy LUMAZINE PROTEIN
(Photobacterium
leiognathi) 		10 / 12 VAL A  41
CYH A  47
SER A  48
THR A  50
ASP A  64
GLN A  65
ALA A  66
THR A  69
THR A  70
ILE A 102
 RBF  A 187 ( 4.5A)
RBF  A 187 (-3.3A)
RBF  A 187 (-4.3A)
RBF  A 187 (-4.4A)
RBF  A 187 (-4.4A)
RBF  A 187 (-3.7A)
RBF  A 187 (-3.1A)
RBF  A 187 (-3.2A)
None
RBF  A 187 (-4.4A)
 0.36A 3a35A-3ddyA:
29.7		 3a35A-3ddyA:
55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 3ddy LUMAZINE PROTEIN
(Photobacterium
leiognathi) 		6 / 12 CYH A  47
ASP A  64
GLN A  65
ALA A  66
ASN A 101
ILE A 102
 RBF  A 187 (-3.3A)
RBF  A 187 (-4.4A)
RBF  A 187 (-3.7A)
RBF  A 187 (-3.1A)
RBF  A 187 (-3.7A)
RBF  A 187 (-4.4A)
 0.79A 3a35B-3ddyA:
30.7		 3a35B-3ddyA:
55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 3ddy LUMAZINE PROTEIN
(Photobacterium
leiognathi) 		10 / 12 VAL A  41
CYH A  47
SER A  48
THR A  50
ASP A  64
GLN A  65
ALA A  66
THR A  69
THR A  70
ILE A 102
 RBF  A 187 ( 4.5A)
RBF  A 187 (-3.3A)
RBF  A 187 (-4.3A)
RBF  A 187 (-4.4A)
RBF  A 187 (-4.4A)
RBF  A 187 (-3.7A)
RBF  A 187 (-3.1A)
RBF  A 187 (-3.2A)
None
RBF  A 187 (-4.4A)
 0.33A 3a35B-3ddyA:
30.7		 3a35B-3ddyA:
55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 3ddy LUMAZINE PROTEIN
(Photobacterium
leiognathi) 		7 / 12 CYH A  47
ASP A  64
GLN A  65
ALA A  66
THR A  70
ASN A 101
ILE A 102
 RBF  A 187 (-3.3A)
RBF  A 187 (-4.4A)
RBF  A 187 (-3.7A)
RBF  A 187 (-3.1A)
None
RBF  A 187 (-3.7A)
RBF  A 187 (-4.4A)
 0.80A 3a3bA-3ddyA:
29.3		 3a3bA-3ddyA:
55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 3ddy LUMAZINE PROTEIN
(Photobacterium
leiognathi) 		10 / 12 VAL A  41
CYH A  47
SER A  48
THR A  50
ASP A  64
GLN A  65
ALA A  66
THR A  69
THR A  70
ILE A 102
 RBF  A 187 ( 4.5A)
RBF  A 187 (-3.3A)
RBF  A 187 (-4.3A)
RBF  A 187 (-4.4A)
RBF  A 187 (-4.4A)
RBF  A 187 (-3.7A)
RBF  A 187 (-3.1A)
RBF  A 187 (-3.2A)
None
RBF  A 187 (-4.4A)
 0.37A 3a3bA-3ddyA:
29.3		 3a3bA-3ddyA:
55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 3ddy LUMAZINE PROTEIN
(Photobacterium
leiognathi) 		8 / 12 VAL A  41
SER A  48
THR A  50
ASP A  64
GLN A  65
ALA A  66
THR A  70
ILE A 102
 RBF  A 187 ( 4.5A)
RBF  A 187 (-4.3A)
RBF  A 187 (-4.4A)
RBF  A 187 (-4.4A)
RBF  A 187 (-3.7A)
RBF  A 187 (-3.1A)
None
RBF  A 187 (-4.4A)
 1.48A 3a3bA-3ddyA:
29.3		 3a3bA-3ddyA:
55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F8F_A_DM1A127_1
(TRANSCRIPTIONAL
REGULATOR, PADR-LIKE
FAMILY)		 4zzd TRANSCRIPTIONAL
REGULATOR, PADR-LIKE
FAMILY
(Lactococcus
lactis) 		6 / 10 MET A   8
ALA A  11
VAL A  15
ALA A  92
PHE A  93
TRP A  96
 None
RBF  A 201 (-3.6A)
RBF  A 201 (-4.7A)
RBF  A 201 ( 4.5A)
None
RBF  A 201 (-3.2A)
 0.70A 3f8fA-4zzdA:
16.4
3f8fB-4zzdA:
16.3		 3f8fA-4zzdA:
100.00
3f8fB-4zzdA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_B_SAMB302_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 5w4z RIBOFLAVIN LYASE
(Herbiconiux) 		5 / 12 GLY A 244
GLY A 231
GLY A 236
SER A 340
ALA A 230
 None
9WY  A 501 (-3.3A)
9WY  A 501 ( 4.5A)
RBF  A 502 (-3.1A)
9WY  A 501 (-3.4A)
 1.06A 3kkzB-5w4zA:
undetectable		 3kkzB-5w4zA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 5kbw RIBOFLAVIN
TRANSPORTER RIBU
(Thermotoga
maritima) 		6 / 12 LEU A  34
ASP A  73
GLY A  76
ASN A 123
ASN A 149
LYS A 152
 RBF  A 201 (-4.9A)
RBF  A 201 (-4.0A)
RBF  A 201 (-2.9A)
RBF  A 201 (-2.1A)
RBF  A 201 (-1.8A)
RBF  A 201 (-3.7A)
 0.87A 3p5nA-5kbwA:
24.2		 3p5nA-5kbwA:
33.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 5kbw RIBOFLAVIN
TRANSPORTER RIBU
(Thermotoga
maritima) 		6 / 12 LEU A  34
ASP A  73
GLY A  76
LEU A  83
ASN A 149
LYS A 152
 RBF  A 201 (-4.9A)
RBF  A 201 (-4.0A)
RBF  A 201 (-2.9A)
RBF  A 201 (-4.5A)
RBF  A 201 (-1.8A)
RBF  A 201 (-3.7A)
 1.38A 3p5nA-5kbwA:
24.2		 3p5nA-5kbwA:
33.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 5kbw RIBOFLAVIN
TRANSPORTER RIBU
(Thermotoga
maritima) 		6 / 12 LEU A  34
ASP A  73
GLY A  76
ASN A 123
ASN A 149
LYS A 152
 RBF  A 201 (-4.9A)
RBF  A 201 (-4.0A)
RBF  A 201 (-2.9A)
RBF  A 201 (-2.1A)
RBF  A 201 (-1.8A)
RBF  A 201 (-3.7A)
 0.88A 3p5nB-5kbwA:
24.2		 3p5nB-5kbwA:
33.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 5kbw RIBOFLAVIN
TRANSPORTER RIBU
(Thermotoga
maritima) 		6 / 12 LEU A  34
ASP A  73
GLY A  76
LEU A  83
ASN A 149
LYS A 152
 RBF  A 201 (-4.9A)
RBF  A 201 (-4.0A)
RBF  A 201 (-2.9A)
RBF  A 201 (-4.5A)
RBF  A 201 (-1.8A)
RBF  A 201 (-3.7A)
 1.39A 3p5nB-5kbwA:
24.2		 3p5nB-5kbwA:
33.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPS_A_CHDA211_0
(CMER)		 5kbw RIBOFLAVIN
TRANSPORTER RIBU
(Thermotoga
maritima) 		5 / 10 LEU A  83
ALA A 117
PHE A 118
GLY A 121
PHE A 148
 RBF  A 201 (-4.5A)
None
None
None
RBF  A 201 (-4.9A)
 1.39A 3qpsA-5kbwA:
3.2		 3qpsA-5kbwA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_B_9PLB1_1
(CYTOCHROME P450 2A13)		 5w4z RIBOFLAVIN LYASE
(Herbiconiux) 		4 / 6 PHE A  14
ASN A  16
ALA A  63
THR A 143
 RBF  A 502 (-3.6A)
RBF  A 502 (-3.8A)
RBF  A 502 ( 3.8A)
None
 1.05A 3t3sB-5w4zA:
undetectable		 3t3sB-5w4zA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_E_9PLE1_1
(CYTOCHROME P450 2A13)		 5w4z RIBOFLAVIN LYASE
(Herbiconiux) 		4 / 8 PHE A  14
ASN A  16
ALA A  63
THR A 143
 RBF  A 502 (-3.6A)
RBF  A 502 (-3.8A)
RBF  A 502 ( 3.8A)
None
 1.09A 3t3sE-5w4zA:
undetectable		 3t3sE-5w4zA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_2
(ADENOSINE KINASE,
PUTATIVE)		 4r3a BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		4 / 5 LEU A  20
GLY A 116
PHE A  18
ASN A  97
 None
RBF  A 402 ( 3.8A)
None
RBF  A 402 (-4.0A)
 1.25A 3uq6B-4r3aA:
undetectable		 3uq6B-4r3aA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZS3_A_ACTA1226_0
(THAUMATIN-LIKE
PROTEIN)		 5kbw RIBOFLAVIN
TRANSPORTER RIBU
(Thermotoga
maritima) 		4 / 5 GLU A  40
ASP A 156
ASN A 149
PHE A 148
 None
None
RBF  A 201 (-1.8A)
RBF  A 201 (-4.9A)
 1.25A 3zs3A-5kbwA:
0.0		 3zs3A-5kbwA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)		 4d1y PUTATIVE PROTEASE I
(Bacteroides
thetaiotaomicron) 		5 / 9 ASN A  14
GLY A  15
GLY A  17
ASN A 161
SER A  47
 None
None
None
RBF  A1176 (-4.2A)
None
 1.14A 3ztvA-4d1yA:
undetectable		 3ztvA-4d1yA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5kbw RIBOFLAVIN
TRANSPORTER RIBU
(Thermotoga
maritima) 		4 / 7 ASP A  63
ASP A 156
ASN A  80
GLU A  24
 None
None
None
RBF  A 201 (-4.1A)
 1.20A 4fevD-5kbwA:
undetectable		 4fevD-5kbwA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5kbw RIBOFLAVIN
TRANSPORTER RIBU
(Thermotoga
maritima) 		4 / 7 ASP A  63
ASP A 156
ASN A  80
GLU A  24
 None
None
None
RBF  A 201 (-4.1A)
 1.21A 4fevF-5kbwA:
undetectable		 4fevF-5kbwA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5kbw RIBOFLAVIN
TRANSPORTER RIBU
(Thermotoga
maritima) 		4 / 8 ASP A  63
ASP A 156
ASN A  80
GLU A  24
 None
None
None
RBF  A 201 (-4.1A)
 1.21A 4fewD-5kbwA:
undetectable		 4fewD-5kbwA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5kbw RIBOFLAVIN
TRANSPORTER RIBU
(Thermotoga
maritima) 		4 / 8 ASP A  63
ASP A 156
ASN A  80
GLU A  24
 None
None
None
RBF  A 201 (-4.1A)
 1.22A 4fewF-5kbwA:
undetectable		 4fewF-5kbwA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5kbw RIBOFLAVIN
TRANSPORTER RIBU
(Thermotoga
maritima) 		4 / 8 ASP A  63
ASP A 156
ASN A  80
GLU A  24
 None
None
None
RBF  A 201 (-4.1A)
 1.15A 4gkhB-5kbwA:
undetectable		 4gkhB-5kbwA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5kbw RIBOFLAVIN
TRANSPORTER RIBU
(Thermotoga
maritima) 		4 / 7 ASP A  63
ASP A 156
ASN A  80
GLU A  24
 None
None
None
RBF  A 201 (-4.1A)
 1.20A 4gkhG-5kbwA:
undetectable		 4gkhG-5kbwA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5kbw RIBOFLAVIN
TRANSPORTER RIBU
(Thermotoga
maritima) 		4 / 8 ASP A  63
ASP A 156
ASN A  80
GLU A  24
 None
None
None
RBF  A 201 (-4.1A)
 1.19A 4gkiA-5kbwA:
undetectable		 4gkiA-5kbwA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5kbw RIBOFLAVIN
TRANSPORTER RIBU
(Thermotoga
maritima) 		4 / 8 ASP A  63
ASP A 156
ASN A  80
GLU A  24
 None
None
None
RBF  A 201 (-4.1A)
 1.11A 4gkiC-5kbwA:
undetectable		 4gkiC-5kbwA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 3p5n RIBOFLAVIN UPTAKE
PROTEIN
(Staphylococcus
aureus) 		4 / 8 ILE A 113
LYS A 167
ILE A 173
PHE A 175
 None
RBF  A 190 (-3.2A)
None
None
 0.98A 4hdlA-3p5nA:
undetectable		 4hdlA-3p5nA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4iil MEMBRANE LIPOPROTEIN
TPN38(B)
(Treponema
pallidum) 		4 / 5 PRO A  83
ASP A 105
ILE A 164
VAL A 286
 RBF  A 401 ( 3.7A)
RBF  A 401 (-3.2A)
RBF  A 401 ( 4.7A)
None
 1.43A 4hytA-4iilA:
2.1		 4hytA-4iilA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_A_SAMA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 4iil MEMBRANE LIPOPROTEIN
TPN38(B)
(Treponema
pallidum) 		5 / 12 VAL A 221
GLY A 154
GLY A 187
ILE A 152
ILE A 213
 None
None
None
None
RBF  A 401 (-3.7A)
 0.98A 4iv0A-4iilA:
undetectable		 4iv0A-4iilA:
24.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 4r38 BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		8 / 12 ASN A  54
CYH A  55
ARG A  56
GLN A  59
ASN A  87
ASN A  97
LEU A  99
GLN A 118
 RBF  A 201 (-2.6A)
RBF  A 201 (-3.3A)
RBF  A 201 (-3.7A)
RBF  A 201 (-3.0A)
RBF  A 201 (-2.4A)
RBF  A 201 (-3.7A)
RBF  A 201 (-4.2A)
RBF  A 201 (-4.0A)
 0.39A 4kukA-4r38A:
18.4		 4kukA-4r38A:
36.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 4r3a BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		8 / 12 ASN A  54
CYH A  55
ARG A  56
GLN A  59
ASN A  87
ASN A  97
LEU A  99
GLN A 118
 RBF  A 402 (-2.9A)
RBF  A 402 (-3.4A)
RBF  A 402 (-3.6A)
RBF  A 402 (-3.3A)
RBF  A 402 (-2.3A)
RBF  A 402 (-4.0A)
RBF  A 402 (-4.3A)
RBF  A 402 (-4.3A)
 0.34A 4kukA-4r3aA:
14.6		 4kukA-4r3aA:
16.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUK_A_RBFA201_2
(BLUE-LIGHT
PHOTORECEPTOR)		 4r38 BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		5 / 9 LEU A  58
VAL A  68
ILE A  85
PHE A 114
GLY A 116
 RBF  A 201 (-3.9A)
RBF  A 201 (-3.3A)
RBF  A 201 ( 4.2A)
RBF  A 201 (-4.4A)
RBF  A 201 ( 3.3A)
 0.58A 4kukA-4r38A:
18.4		 4kukA-4r38A:
36.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_2
(BLUE-LIGHT
PHOTORECEPTOR)		 4r3a BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		5 / 9 LEU A  58
VAL A  68
ILE A  85
PHE A 114
GLY A 116
 RBF  A 402 (-4.2A)
RBF  A 402 (-3.5A)
RBF  A 402 (-4.0A)
RBF  A 402 ( 4.3A)
RBF  A 402 ( 3.8A)
 0.42A 4kukA-4r3aA:
14.6		 4kukA-4r3aA:
16.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 4r38 BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		8 / 12 ASN A  54
CYH A  55
ARG A  56
GLN A  59
ASN A  87
ASN A  97
LEU A  99
GLN A 118
 RBF  A 201 (-2.6A)
RBF  A 201 (-3.3A)
RBF  A 201 (-3.7A)
RBF  A 201 (-3.0A)
RBF  A 201 (-2.4A)
RBF  A 201 (-3.7A)
RBF  A 201 (-4.2A)
RBF  A 201 (-4.0A)
 0.35A 4kuoA-4r38A:
18.6		 4kuoA-4r38A:
36.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 4r3a BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		8 / 12 ASN A  54
CYH A  55
ARG A  56
GLN A  59
ASN A  87
ASN A  97
LEU A  99
GLN A 118
 RBF  A 402 (-2.9A)
RBF  A 402 (-3.4A)
RBF  A 402 (-3.6A)
RBF  A 402 (-3.3A)
RBF  A 402 (-2.3A)
RBF  A 402 (-4.0A)
RBF  A 402 (-4.3A)
RBF  A 402 (-4.3A)
 0.35A 4kuoA-4r3aA:
14.7		 4kuoA-4r3aA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 4iil MEMBRANE LIPOPROTEIN
TPN38(B)
(Treponema
pallidum) 		5 / 12 VAL A 221
GLY A 154
GLY A 187
ILE A 152
ILE A 213
 None
None
None
None
RBF  A 401 (-3.7A)
 0.99A 4mwzB-4iilA:
undetectable		 4mwzB-4iilA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4r38 BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		5 / 12 SER A  46
ALA A  90
PHE A  39
LEU A  99
VAL A  35
 None
None
None
RBF  A 201 (-4.2A)
None
 1.32A 4nc3A-4r38A:
undetectable		 4nc3A-4r38A:
17.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4r3a BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		12 / 12 ALA A  23
CYH A  55
ARG A  56
GLN A  59
ALA A  72
ILE A  75
ASN A  87
ASN A  97
LEU A  99
MET A 101
GLY A 116
GLN A 118
 RBF  A 402 ( 2.9A)
RBF  A 402 (-3.4A)
RBF  A 402 (-3.6A)
RBF  A 402 (-3.3A)
RBF  A 402 ( 3.1A)
RBF  A 402 (-4.3A)
RBF  A 402 (-2.3A)
RBF  A 402 (-4.0A)
RBF  A 402 (-4.3A)
RBF  A 402 (-3.2A)
RBF  A 402 ( 3.8A)
RBF  A 402 (-4.3A)
 0.31A 4r38A-4r3aA:
4.2		 4r38A-4r3aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4r3a BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		5 / 12 ALA A  74
GLN A 118
ALA A  23
ASN A  97
ASN A  87
 None
RBF  A 402 (-4.3A)
RBF  A 402 ( 2.9A)
RBF  A 402 (-4.0A)
RBF  A 402 (-2.3A)
 1.20A 4r38A-4r3aA:
4.2		 4r38A-4r3aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_A_RBFA201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4r3a BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		8 / 8 THR A  21
ILE A  25
ASN A  54
LEU A  58
VAL A  68
LEU A  71
ILE A  85
PHE A 114
 RBF  A 402 (-3.4A)
None
RBF  A 402 (-2.9A)
RBF  A 402 (-4.2A)
RBF  A 402 (-3.5A)
RBF  A 402 (-3.6A)
RBF  A 402 (-4.0A)
RBF  A 402 ( 4.3A)
 0.32A 4r38A-4r3aA:
4.2		 4r38A-4r3aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4r3a BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		12 / 12 ALA A  23
ASN A  54
CYH A  55
ARG A  56
GLN A  59
ALA A  72
ILE A  75
ASN A  87
ASN A  97
LEU A  99
GLY A 116
GLN A 118
 RBF  A 402 ( 2.9A)
RBF  A 402 (-2.9A)
RBF  A 402 (-3.4A)
RBF  A 402 (-3.6A)
RBF  A 402 (-3.3A)
RBF  A 402 ( 3.1A)
RBF  A 402 (-4.3A)
RBF  A 402 (-2.3A)
RBF  A 402 (-4.0A)
RBF  A 402 (-4.3A)
RBF  A 402 ( 3.8A)
RBF  A 402 (-4.3A)
 0.31A 4r38B-4r3aA:
16.8		 4r38B-4r3aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4r3a BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		5 / 12 ALA A  23
ASN A  54
CYH A  55
ILE A  75
ASN A  87
 RBF  A 402 ( 2.9A)
RBF  A 402 (-2.9A)
RBF  A 402 (-3.4A)
RBF  A 402 (-4.3A)
RBF  A 402 (-2.3A)
 1.06A 4r38B-4r3aA:
16.8		 4r38B-4r3aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4r3a BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		5 / 12 ALA A  23
CYH A  55
ALA A  72
ILE A  75
ASN A  97
 RBF  A 402 ( 2.9A)
RBF  A 402 (-3.4A)
RBF  A 402 ( 3.1A)
RBF  A 402 (-4.3A)
RBF  A 402 (-4.0A)
 1.12A 4r38B-4r3aA:
16.8		 4r38B-4r3aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4r3a BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		5 / 12 ALA A  74
GLN A 118
ALA A  23
ASN A  97
ASN A  87
 None
RBF  A 402 (-4.3A)
RBF  A 402 ( 2.9A)
RBF  A 402 (-4.0A)
RBF  A 402 (-2.3A)
 1.22A 4r38B-4r3aA:
16.8		 4r38B-4r3aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4r3a BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		5 / 12 ALA A  23
CYH A  55
ALA A  72
ILE A  75
ASN A  87
 RBF  A 402 ( 2.9A)
RBF  A 402 (-3.4A)
RBF  A 402 ( 3.1A)
RBF  A 402 (-4.3A)
RBF  A 402 (-2.3A)
 1.01A 4r38C-4r3aA:
16.9		 4r38C-4r3aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4r3a BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		12 / 12 ALA A  23
CYH A  55
ARG A  56
GLN A  59
ALA A  72
ILE A  75
ASN A  87
ASN A  97
LEU A  99
MET A 101
GLY A 116
GLN A 118
 RBF  A 402 ( 2.9A)
RBF  A 402 (-3.4A)
RBF  A 402 (-3.6A)
RBF  A 402 (-3.3A)
RBF  A 402 ( 3.1A)
RBF  A 402 (-4.3A)
RBF  A 402 (-2.3A)
RBF  A 402 (-4.0A)
RBF  A 402 (-4.3A)
RBF  A 402 (-3.2A)
RBF  A 402 ( 3.8A)
RBF  A 402 (-4.3A)
 0.33A 4r38C-4r3aA:
16.9		 4r38C-4r3aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4r3a BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		5 / 12 ALA A  74
GLN A 118
ALA A  23
ASN A  97
ASN A  87
 None
RBF  A 402 (-4.3A)
RBF  A 402 ( 2.9A)
RBF  A 402 (-4.0A)
RBF  A 402 (-2.3A)
 1.15A 4r38C-4r3aA:
16.9		 4r38C-4r3aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4r3a BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		9 / 9 THR A  21
ILE A  25
GLU A  30
ASN A  54
LEU A  58
VAL A  68
LEU A  71
ILE A  85
PHE A 114
 RBF  A 402 (-3.4A)
None
None
RBF  A 402 (-2.9A)
RBF  A 402 (-4.2A)
RBF  A 402 (-3.5A)
RBF  A 402 (-3.6A)
RBF  A 402 (-4.0A)
RBF  A 402 ( 4.3A)
 0.48A 4r38C-4r3aA:
16.9		 4r38C-4r3aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4r3a BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		12 / 12 ALA A  23
CYH A  55
ARG A  56
GLN A  59
ALA A  72
ILE A  75
ASN A  87
ASN A  97
LEU A  99
MET A 101
GLY A 116
GLN A 118
 RBF  A 402 ( 2.9A)
RBF  A 402 (-3.4A)
RBF  A 402 (-3.6A)
RBF  A 402 (-3.3A)
RBF  A 402 ( 3.1A)
RBF  A 402 (-4.3A)
RBF  A 402 (-2.3A)
RBF  A 402 (-4.0A)
RBF  A 402 (-4.3A)
RBF  A 402 (-3.2A)
RBF  A 402 ( 3.8A)
RBF  A 402 (-4.3A)
 0.34A 4r38D-4r3aA:
4.0		 4r38D-4r3aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4r3a BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		5 / 12 ALA A  74
GLN A 118
ALA A  23
ASN A  97
ASN A  87
 None
RBF  A 402 (-4.3A)
RBF  A 402 ( 2.9A)
RBF  A 402 (-4.0A)
RBF  A 402 (-2.3A)
 1.18A 4r38D-4r3aA:
4.0		 4r38D-4r3aA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R3A_A_RBFA402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4r38 BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		6 / 12 ALA A  23
CYH A  55
ALA A  72
ILE A  75
ILE A  85
ASN A  87
 RBF  A 201 ( 3.4A)
RBF  A 201 (-3.3A)
RBF  A 201 ( 3.3A)
RBF  A 201 (-4.2A)
RBF  A 201 ( 4.2A)
RBF  A 201 (-2.4A)
 1.35A 4r3aA-4r38A:
17.0		 4r3aA-4r38A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R3A_A_RBFA402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4r38 BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		12 / 12 ALA A  23
CYH A  55
ARG A  56
GLN A  59
ALA A  72
ILE A  75
ILE A  85
ASN A  87
ASN A  97
LEU A  99
MET A 101
GLN A 118
 RBF  A 201 ( 3.4A)
RBF  A 201 (-3.3A)
RBF  A 201 (-3.7A)
RBF  A 201 (-3.0A)
RBF  A 201 ( 3.3A)
RBF  A 201 (-4.2A)
RBF  A 201 ( 4.2A)
RBF  A 201 (-2.4A)
RBF  A 201 (-3.7A)
RBF  A 201 (-4.2A)
RBF  A 201 (-3.2A)
RBF  A 201 (-4.0A)
 0.34A 4r3aA-4r38A:
17.0		 4r3aA-4r38A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R3A_B_RBFB402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4r38 BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		10 / 10 THR A  21
ILE A  25
GLU A  30
ASN A  54
LEU A  58
GLN A  59
VAL A  68
LEU A  71
MET A 101
PHE A 114
 RBF  A 201 (-3.1A)
None
None
RBF  A 201 (-2.6A)
RBF  A 201 (-3.9A)
RBF  A 201 (-3.0A)
RBF  A 201 (-3.3A)
RBF  A 201 ( 3.6A)
RBF  A 201 (-3.2A)
RBF  A 201 (-4.4A)
 0.59A 4r3aB-4r38A:
16.8		 4r3aB-4r38A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R3A_B_RBFB402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4r38 BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		5 / 10 THR A  21
ILE A  75
LEU A  58
MET A 101
PHE A 114
 RBF  A 201 (-3.1A)
RBF  A 201 (-4.2A)
RBF  A 201 (-3.9A)
RBF  A 201 (-3.2A)
RBF  A 201 (-4.4A)
 1.42A 4r3aB-4r38A:
16.8		 4r3aB-4r38A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4r38 BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		7 / 12 ALA A  23
LEU A  32
CYH A  55
ALA A  72
ILE A  75
ILE A  85
ASN A  87
 RBF  A 201 ( 3.4A)
None
RBF  A 201 (-3.3A)
RBF  A 201 ( 3.3A)
RBF  A 201 (-4.2A)
RBF  A 201 ( 4.2A)
RBF  A 201 (-2.4A)
 1.33A 4r3aB-4r38A:
16.8		 4r3aB-4r38A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4r38 BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		12 / 12 ALA A  23
LEU A  32
CYH A  55
ARG A  56
ALA A  72
ILE A  75
ILE A  85
ASN A  87
ASN A  97
LEU A  99
GLY A 116
GLN A 118
 RBF  A 201 ( 3.4A)
None
RBF  A 201 (-3.3A)
RBF  A 201 (-3.7A)
RBF  A 201 ( 3.3A)
RBF  A 201 (-4.2A)
RBF  A 201 ( 4.2A)
RBF  A 201 (-2.4A)
RBF  A 201 (-3.7A)
RBF  A 201 (-4.2A)
RBF  A 201 ( 3.3A)
RBF  A 201 (-4.0A)
 0.48A 4r3aB-4r38A:
16.8		 4r3aB-4r38A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4r38 BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		6 / 12 ALA A  23
LEU A  32
CYH A  55
ARG A  56
ILE A  75
ASN A  97
 RBF  A 201 ( 3.4A)
None
RBF  A 201 (-3.3A)
RBF  A 201 (-3.7A)
RBF  A 201 (-4.2A)
RBF  A 201 (-3.7A)
 1.05A 4r3aB-4r38A:
16.8		 4r3aB-4r38A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 3p5n RIBOFLAVIN UPTAKE
PROTEIN
(Staphylococcus
aureus) 		4 / 4 VAL A 134
ILE A 129
ASN A 164
VAL A 157
 None
None
RBF  A 190 (-3.3A)
None
 1.03A 5ajqA-3p5nA:
undetectable		 5ajqA-3p5nA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5kbw RIBOFLAVIN
TRANSPORTER RIBU
(Thermotoga
maritima) 		5 / 12 PHE A  33
LEU A  34
ALA A  31
TYR A 138
ILE A 145
 RBF  A 201 (-4.4A)
RBF  A 201 (-4.9A)
None
None
RBF  A 201 ( 4.6A)
 1.08A 5h8tA-5kbwA:
undetectable		 5h8tA-5kbwA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4e0f RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA
(Brucella
abortus) 		5 / 10 ALA A  67
VAL A  65
GLU A  66
ASP A  13
ILE A  26
 RBF  A 301 (-4.1A)
None
None
None
None
 1.04A 5i3cB-4e0fA:
undetectable		 5i3cB-4e0fA:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KBW_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3p5n RIBOFLAVIN UPTAKE
PROTEIN
(Staphylococcus
aureus) 		7 / 12 LEU A  42
ASP A  81
GLY A  84
ASN A  88
ASN A 131
ASN A 164
LYS A 167
 RBF  A 190 (-4.6A)
RBF  A 190 (-3.0A)
RBF  A 190 (-3.1A)
RBF  A 190 ( 4.9A)
RBF  A 190 (-3.6A)
RBF  A 190 (-3.3A)
RBF  A 190 (-3.2A)
 0.82A 5kbwA-3p5nA:
24.2		 5kbwA-3p5nA:
33.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KBW_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3p5n RIBOFLAVIN UPTAKE
PROTEIN
(Staphylococcus
aureus) 		6 / 12 LEU A  42
ASP A  81
GLY A  84
LEU A 127
ASN A 164
LYS A 167
 RBF  A 190 (-4.6A)
RBF  A 190 (-3.0A)
RBF  A 190 (-3.1A)
RBF  A 190 (-4.1A)
RBF  A 190 (-3.3A)
RBF  A 190 (-3.2A)
 1.38A 5kbwA-3p5nA:
24.2		 5kbwA-3p5nA:
33.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3p5n RIBOFLAVIN UPTAKE
PROTEIN
(Staphylococcus
aureus) 		5 / 12 ASP A  81
GLY A  84
ASN A  88
ASN A 131
ASN A 164
 RBF  A 190 (-3.0A)
RBF  A 190 (-3.1A)
RBF  A 190 ( 4.9A)
RBF  A 190 (-3.6A)
RBF  A 190 (-3.3A)
 0.65A 5kbwB-3p5nA:
24.1		 5kbwB-3p5nA:
33.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3p5n RIBOFLAVIN UPTAKE
PROTEIN
(Staphylococcus
aureus) 		5 / 12 ASP A  81
GLY A  84
ASN A  88
ASN A 131
LYS A 167
 RBF  A 190 (-3.0A)
RBF  A 190 (-3.1A)
RBF  A 190 ( 4.9A)
RBF  A 190 (-3.6A)
RBF  A 190 (-3.2A)
 0.73A 5kbwB-3p5nA:
24.1		 5kbwB-3p5nA:
33.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3p5n RIBOFLAVIN UPTAKE
PROTEIN
(Staphylococcus
aureus) 		5 / 12 LEU A  42
GLY A  84
ASN A  88
ASN A 131
ASN A 164
 RBF  A 190 (-4.6A)
RBF  A 190 (-3.1A)
RBF  A 190 ( 4.9A)
RBF  A 190 (-3.6A)
RBF  A 190 (-3.3A)
 0.49A 5kbwB-3p5nA:
24.1		 5kbwB-3p5nA:
33.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3p5n RIBOFLAVIN UPTAKE
PROTEIN
(Staphylococcus
aureus) 		5 / 12 LEU A  42
GLY A  84
ASN A  88
ASN A 131
LYS A 167
 RBF  A 190 (-4.6A)
RBF  A 190 (-3.1A)
RBF  A 190 ( 4.9A)
RBF  A 190 (-3.6A)
RBF  A 190 (-3.2A)
 0.56A 5kbwB-3p5nA:
24.1		 5kbwB-3p5nA:
33.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KC0_A_RBFA303_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3p5n RIBOFLAVIN UPTAKE
PROTEIN
(Staphylococcus
aureus) 		7 / 12 LEU A  42
ASP A  81
GLY A  84
ASN A  88
ASN A 131
ASN A 164
LYS A 167
 RBF  A 190 (-4.6A)
RBF  A 190 (-3.0A)
RBF  A 190 (-3.1A)
RBF  A 190 ( 4.9A)
RBF  A 190 (-3.6A)
RBF  A 190 (-3.3A)
RBF  A 190 (-3.2A)
 1.00A 5kc0A-3p5nA:
24.0		 5kc0A-3p5nA:
31.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KC0_A_RBFA303_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 5kbw RIBOFLAVIN
TRANSPORTER RIBU
(Thermotoga
maritima) 		12 / 12 GLU A  24
LEU A  34
LYS A  70
ASP A  73
GLY A  76
MET A  79
ASN A  80
ALA A 119
ASN A 123
ASN A 149
LYS A 152
PHE A 153
 RBF  A 201 (-4.1A)
RBF  A 201 (-4.9A)
RBF  A 201 ( 4.0A)
RBF  A 201 (-4.0A)
RBF  A 201 (-2.9A)
RBF  A 201 (-3.5A)
None
RBF  A 201 (-3.3A)
RBF  A 201 (-2.1A)
RBF  A 201 (-1.8A)
RBF  A 201 (-3.7A)
RBF  A 201 ( 4.7A)
 0.60A 5kc0A-5kbwA:
29.3		 5kc0A-5kbwA:
94.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KC4_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3p5n RIBOFLAVIN UPTAKE
PROTEIN
(Staphylococcus
aureus) 		7 / 12 LEU A  42
ASP A  81
GLY A  84
ASN A  88
ASN A 131
ASN A 164
LYS A 167
 RBF  A 190 (-4.6A)
RBF  A 190 (-3.0A)
RBF  A 190 (-3.1A)
RBF  A 190 ( 4.9A)
RBF  A 190 (-3.6A)
RBF  A 190 (-3.3A)
RBF  A 190 (-3.2A)
 1.04A 5kc4A-3p5nA:
23.6		 5kc4A-3p5nA:
33.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KC4_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 5kbw RIBOFLAVIN
TRANSPORTER RIBU
(Thermotoga
maritima) 		6 / 12 GLU A  24
LEU A  34
ASP A  73
GLY A  76
MET A  79
ASN A 123
 RBF  A 201 (-4.1A)
RBF  A 201 (-4.9A)
RBF  A 201 (-4.0A)
RBF  A 201 (-2.9A)
RBF  A 201 (-3.5A)
RBF  A 201 (-2.1A)
 0.89A 5kc4A-5kbwA:
28.8		 5kc4A-5kbwA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KC4_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 5kbw RIBOFLAVIN
TRANSPORTER RIBU
(Thermotoga
maritima) 		11 / 12 LEU A  34
LYS A  70
ASP A  73
GLY A  76
MET A  79
ASN A  80
ALA A 119
ASN A 123
ASN A 149
LYS A 152
PHE A 153
 RBF  A 201 (-4.9A)
RBF  A 201 ( 4.0A)
RBF  A 201 (-4.0A)
RBF  A 201 (-2.9A)
RBF  A 201 (-3.5A)
None
RBF  A 201 (-3.3A)
RBF  A 201 (-2.1A)
RBF  A 201 (-1.8A)
RBF  A 201 (-3.7A)
RBF  A 201 ( 4.7A)
 0.62A 5kc4A-5kbwA:
28.8		 5kc4A-5kbwA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3p5n RIBOFLAVIN UPTAKE
PROTEIN
(Staphylococcus
aureus) 		8 / 12 LEU A  42
ASP A  81
GLY A  84
ASN A  88
ASN A 131
PHE A 163
ASN A 164
LYS A 167
 RBF  A 190 (-4.6A)
RBF  A 190 (-3.0A)
RBF  A 190 (-3.1A)
RBF  A 190 ( 4.9A)
RBF  A 190 (-3.6A)
RBF  A 190 (-4.5A)
RBF  A 190 (-3.3A)
RBF  A 190 (-3.2A)
 0.95A 5kc4E-3p5nA:
23.4		 5kc4E-3p5nA:
33.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3p5n RIBOFLAVIN UPTAKE
PROTEIN
(Staphylococcus
aureus) 		7 / 12 LEU A  42
ASP A  81
GLY A  84
LEU A 127
PHE A 163
ASN A 164
LYS A 167
 RBF  A 190 (-4.6A)
RBF  A 190 (-3.0A)
RBF  A 190 (-3.1A)
RBF  A 190 (-4.1A)
RBF  A 190 (-4.5A)
RBF  A 190 (-3.3A)
RBF  A 190 (-3.2A)
 1.29A 5kc4E-3p5nA:
23.4		 5kc4E-3p5nA:
33.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 5kbw RIBOFLAVIN
TRANSPORTER RIBU
(Thermotoga
maritima) 		11 / 12 GLU A  24
LEU A  34
ASP A  73
GLY A  76
MET A  79
ASN A  80
LEU A  83
ALA A 119
ASN A 123
PHE A 148
ASN A 149
 RBF  A 201 (-4.1A)
RBF  A 201 (-4.9A)
RBF  A 201 (-4.0A)
RBF  A 201 (-2.9A)
RBF  A 201 (-3.5A)
None
RBF  A 201 (-4.5A)
RBF  A 201 (-3.3A)
RBF  A 201 (-2.1A)
RBF  A 201 (-4.9A)
RBF  A 201 (-1.8A)
 0.71A 5kc4E-5kbwA:
28.4		 5kc4E-5kbwA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 5kbw RIBOFLAVIN
TRANSPORTER RIBU
(Thermotoga
maritima) 		11 / 12 GLU A  24
LEU A  34
ASP A  73
GLY A  76
MET A  79
ASN A  80
LEU A  83
ALA A 119
PHE A 148
ASN A 149
LYS A 152
 RBF  A 201 (-4.1A)
RBF  A 201 (-4.9A)
RBF  A 201 (-4.0A)
RBF  A 201 (-2.9A)
RBF  A 201 (-3.5A)
None
RBF  A 201 (-4.5A)
RBF  A 201 (-3.3A)
RBF  A 201 (-4.9A)
RBF  A 201 (-1.8A)
RBF  A 201 (-3.7A)
 0.72A 5kc4E-5kbwA:
28.4		 5kc4E-5kbwA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 5kbw RIBOFLAVIN
TRANSPORTER RIBU
(Thermotoga
maritima) 		3 / 3 LYS A  35
ASP A  37
ILE A 145
 RBF  A 201 (-3.3A)
None
RBF  A 201 ( 4.6A)
 0.54A 5kc4E-5kbwA:
28.4		 5kc4E-5kbwA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 4r3a BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2
(Erythrobacter
litoralis) 		5 / 12 GLY A 116
THR A  21
ASN A  36
GLN A 118
LEU A 148
 RBF  A 402 ( 3.8A)
RBF  A 402 (-3.4A)
None
RBF  A 402 (-4.3A)
None
 1.07A 5kocB-4r3aA:
undetectable		 5kocB-4r3aA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 3p5n RIBOFLAVIN UPTAKE
PROTEIN
(Staphylococcus
aureus) 		5 / 12 VAL A  49
ASP A  48
GLY A  84
ALA A  91
SER A 128
 None
None
RBF  A 190 (-3.1A)
RBF  A 190 (-3.4A)
None
 1.01A 6c2mC-3p5nA:
undetectable		 6c2mC-3p5nA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 3p5n RIBOFLAVIN UPTAKE
PROTEIN
(Staphylococcus
aureus) 		5 / 12 VAL A  49
ASP A  48
GLY A  84
ALA A  91
VAL A 126
 None
None
RBF  A 190 (-3.1A)
RBF  A 190 (-3.4A)
None
 0.97A 6c2mC-3p5nA:
undetectable		 6c2mC-3p5nA:
17.49