SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'R64'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CCF_B_BEZB261_0 (CYCLOPROPANE-FATTY-A CYL-PHOSPHOLIPID SYNTHASE)	1iyl	MYRISTOYL-COA:PROTEI N N-MYRISTOYLTRANSFERA SE (Candida albicans)	4 / 8	ASN A 392 ILE A 352 PHE A 117 TYR A 354	R64 A 452 (-3.4A) None R64 A 452 ( 4.2A) R64 A 452 ( 4.6A)	1.46A	3ccfB-1iylA: undetectable	3ccfB-1iylA: 20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F8Y_C_VK3C202_1 (NADPH QUINONE OXIDOREDUCTASE)	1iyl	MYRISTOYL-COA:PROTEI N N-MYRISTOYLTRANSFERA SE (Candida albicans)	4 / 7	TYR A 225 LEU A 394 ASN A 392 TYR A 335	R64 A 452 (-3.6A) R64 A 452 (-4.6A) R64 A 452 (-3.4A) None	1.31A	4f8yC-1iylA: undetectable 4f8yD-1iylA: undetectable	4f8yC-1iylA: 18.88 4f8yD-1iylA: 18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F8Y_C_VK3C202_1 (NADPH QUINONE OXIDOREDUCTASE)	1iyl	MYRISTOYL-COA:PROTEI N N-MYRISTOYLTRANSFERA SE (Candida albicans)	4 / 7	TYR A 225 LEU A 415 ASN A 392 TYR A 335	R64 A 452 (-3.6A) None R64 A 452 (-3.4A) None	1.26A	4f8yC-1iylA: undetectable 4f8yD-1iylA: undetectable	4f8yC-1iylA: 18.88 4f8yD-1iylA: 18.88

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3CCF_B_BEZB261_0","CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE","1iyl","MYRISTOYL-COA:PROTEIN N-MYRISTOYLTRANSFERASE","Candida albicans",4,"ASN A 392;ILE A 352;PHE A 117;TYR A 354","R64 A 452 (-3.4A);None;R64 A 452 ( 4.2A);R64 A 452 ( 4.6A)","1.46A","3ccfB-1iylA:undetectable",null],["4F8Y_C_VK3C202_1","NADPH QUINONE OXIDOREDUCTASE;NADPH QUINONE OXIDOREDUCTASE","1iyl","MYRISTOYL-COA:PROTEIN N-MYRISTOYLTRANSFERASE","Candida albicans",4,"TYR A 225;LEU A 394;ASN A 392;TYR A 335","R64 A 452 (-3.6A);R64 A 452 (-4.6A);R64 A 452 (-3.4A);None","1.31A","4f8yC-1iylA:undetectable;4f8yD-1iylA:undetectable","3ccfB-1iylA:20.39"],["4F8Y_C_VK3C202_1","NADPH QUINONE OXIDOREDUCTASE;NADPH QUINONE OXIDOREDUCTASE","1iyl","MYRISTOYL-COA:PROTEIN N-MYRISTOYLTRANSFERASE","Candida albicans",4,"TYR A 225;LEU A 415;ASN A 392;TYR A 335","R64 A 452 (-3.6A);None;R64 A 452 (-3.4A);None","1.26A","4f8yC-1iylA:undetectable;4f8yD-1iylA:undetectable","4f8yC-1iylA:18.88;4f8yD-1iylA:18.88"]]