SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'R03'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CEA_B_ACAB90_1 (PLASMINOGEN)	1h39	SQUALENE--HOPENE CYCLASE (Alicyclobacillus acidocaldarius)	4 / 7	ARG A 488 ASP A 376 ASP A 377 TYR A 420	None R03  A 800 ( 4.1A) R03  A 800 ( 4.3A) R03  A 800 ( 4.9A)	1.39A	1ceaB-1h39A: 0.0	1ceaB-1h39A: 9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CEB_A_AMHA90_1 (PLASMINOGEN)	1h39	SQUALENE--HOPENE CYCLASE (Alicyclobacillus acidocaldarius)	4 / 7	ARG A 488 ASP A 376 ASP A 377 TYR A 420	None R03  A 800 ( 4.1A) R03  A 800 ( 4.3A) R03  A 800 ( 4.9A)	1.25A	1cebA-1h39A: undetectable	1cebA-1h39A: 9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GX9_A_REAA1163_1 (BETA-LACTOGLOBULIN)	1h39	SQUALENE--HOPENE CYCLASE (Alicyclobacillus acidocaldarius)	5 / 11	LEU A 177 VAL A 148 ILE A 432 VAL A 440 PHE A 166	None None None R03  A 800 ( 4.9A) None	1.06A	1gx9A-1h39A: 0.0	1gx9A-1h39A: 13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QCA_A_FUAA221_1 (TYPE III CHLORAMPHENICOL ACETYLTRANSFERASE)	1h39	SQUALENE--HOPENE CYCLASE (Alicyclobacillus acidocaldarius)	4 / 7	CYH A 435 PHE A 166 PHE A 434 LEU A 225	R03  A 800 ( 4.6A) None None None	1.11A	1qcaA-1h39A: undetectable	1qcaA-1h39A: 14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y6R_B_CTCB1385_0 (TETX2 PROTEIN)	1h39	SQUALENE--HOPENE CYCLASE (Alicyclobacillus acidocaldarius)	4 / 8	GLN A 366 GLY A 260 GLY A 600 MET A  42	None None None R03  A 800 ( 4.9A)	0.76A	2y6rB-1h39A: undetectable	2y6rB-1h39A: 22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CCF_A_BEZA261_0 (CYCLOPROPANE-FATTY-A CYL-PHOSPHOLIPID SYNTHASE)	1h39	SQUALENE--HOPENE CYCLASE (Alicyclobacillus acidocaldarius)	4 / 8	GLY A 600 TRP A 312 PHE A 365 TYR A 609	None R03  A 800 (-3.9A) R03  A 800 ( 4.0A) None	1.42A	3ccfA-1h39A: undetectable	3ccfA-1h39A: 17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELW_A_SAMA4633_0 (METHYLTRANSFERASE)	1h39	SQUALENE--HOPENE CYCLASE (Alicyclobacillus acidocaldarius)	6 / 12	GLY A 498 GLY A 490 GLY A 496 THR A 599 LEU A 607 PHE A 365	None None None None None R03  A 800 ( 4.0A)	1.48A	3elwA-1h39A: undetectable	3elwA-1h39A: 17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_A_TFPA201_1 (PROTEIN S100-A4)	1h39	SQUALENE--HOPENE CYCLASE (Alicyclobacillus acidocaldarius)	5 / 9	GLY A 608 PHE A 129 PHE A 605 GLY A 600 PHE A 601	None None R03  A 800 (-3.6A) None R03  A 800 (-4.6A)	1.45A	3ko0A-1h39A: undetectable 3ko0C-1h39A: undetectable	3ko0A-1h39A: 9.28 3ko0C-1h39A: 9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_R_TFPR201_1 (PROTEIN S100-A4)	1h39	SQUALENE--HOPENE CYCLASE (Alicyclobacillus acidocaldarius)	5 / 10	GLY A 608 PHE A 129 PHE A 605 GLY A 600 PHE A 601	None None R03  A 800 (-3.6A) None R03  A 800 (-4.6A)	1.47A	3ko0R-1h39A: 0.0 3ko0T-1h39A: undetectable	3ko0R-1h39A: 9.28 3ko0T-1h39A: 9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V3N_B_MIYB2001_1 (TETX2 PROTEIN)	1h39	SQUALENE--HOPENE CYCLASE (Alicyclobacillus acidocaldarius)	4 / 8	GLN A 366 GLY A 260 GLY A 600 MET A  42	None None None R03  A 800 ( 4.9A)	0.90A	3v3nB-1h39A: undetectable	3v3nB-1h39A: 21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V3N_C_MIYC2001_1 (TETX2 PROTEIN)	1h39	SQUALENE--HOPENE CYCLASE (Alicyclobacillus acidocaldarius)	4 / 8	GLN A 366 GLY A 260 GLY A 600 MET A  42	None None None R03  A 800 ( 4.9A)	0.90A	3v3nC-1h39A: undetectable	3v3nC-1h39A: 21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V3O_B_T1CB405_1 (TETX2 PROTEIN)	1h39	SQUALENE--HOPENE CYCLASE (Alicyclobacillus acidocaldarius)	5 / 12	GLN A 366 GLY A 260 GLY A 600 ASN A  39 MET A  42	None None None None R03  A 800 ( 4.9A)	1.11A	3v3oB-1h39A: 0.0	3v3oB-1h39A: 21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MUB_A_OAQA302_0 (SULFOTRANSFERASE)	1h39	SQUALENE--HOPENE CYCLASE (Alicyclobacillus acidocaldarius)	5 / 12	PRO A 429 HIS A 431 VAL A 440 GLY A 603 ASP A 604	None None R03  A 800 ( 4.9A) None None	1.40A	4mubA-1h39A: undetectable	4mubA-1h39A: 17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZE1_A_X2NA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	1h39	SQUALENE--HOPENE CYCLASE (Alicyclobacillus acidocaldarius)	5 / 12	TYR A 609 GLY A 598 GLY A 167 PHE A 365 THR A 599	None None None R03  A 800 ( 4.0A) None	1.28A	4ze1A-1h39A: 0.0	4ze1A-1h39A: 21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DV4_A_NMYA601_2 (CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 6-LIKE)	1h39	SQUALENE--HOPENE CYCLASE (Alicyclobacillus acidocaldarius)	3 / 3	GLU A 446 TRP A 489 ASN A 492	None R03  A 800 (-4.7A) None	0.70A	5dv4A-1h39A: undetectable	5dv4A-1h39A: 22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HWA_A_GCSA302_1 (CHITOSANASE)	1h39	SQUALENE--HOPENE CYCLASE (Alicyclobacillus acidocaldarius)	4 / 7	ASP A 447 ASP A 376 GLY A 418 TYR A 474	None R03  A 800 ( 4.1A) None None	1.03A	5hwaA-1h39A: 0.0	5hwaA-1h39A: 17.12