SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'QRP'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IGY_A_ERYA403_1 (MACROLIDE 2'-PHOSPHOTRANSFERAS E II)	3o2k	BREVIANAMIDE F PRENYLTRANSFERASE (Aspergillus fumigatus)	4 / 6	TYR A 446 ASP A 191 ILE A 112 TYR A 203	DST A 501 (-4.7A) DST A 501 ( 4.1A) None QRP A 502 ( 3.4A)	1.28A	5igyA-3o2kA: undetectable	5igyA-3o2kA: 22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B89_A_NOVA403_1 (LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB)	3o2k	BREVIANAMIDE F PRENYLTRANSFERASE (Aspergillus fumigatus)	5 / 10	LEU A 96 ALA A 434 PRO A 362 SER A 298 PHE A 280	QRP A 502 (-4.3A) None None None QRP A 502 (-4.3A)	1.48A	6b89A-3o2kA: 0.0	6b89A-3o2kA: 10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B89_B_NOVB403_2 (LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB)	3o2k	BREVIANAMIDE F PRENYLTRANSFERASE (Aspergillus fumigatus)	5 / 10	LEU A 96 ALA A 434 PRO A 362 SER A 298 PHE A 280	QRP A 502 (-4.3A) None None None QRP A 502 (-4.3A)	1.43A	6b89B-3o2kA: undetectable	6b89B-3o2kA: 10.89

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["5IGY_A_ERYA403_1","MACROLIDE 2'-PHOSPHOTRANSFERASE II","3o2k","BREVIANAMIDE F PRENYLTRANSFERASE","Aspergillus fumigatus",4,"TYR A 446;ASP A 191;ILE A 112;TYR A 203","DST A 501 (-4.7A);DST A 501 ( 4.1A);None;QRP A 502 ( 3.4A)","1.28A","5igyA-3o2kA:undetectable",null],["6B89_A_NOVA403_1","LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB","3o2k","BREVIANAMIDE F PRENYLTRANSFERASE","Aspergillus fumigatus",5,"LEU A  96;ALA A 434;PRO A 362;SER A 298;PHE A 280","QRP A 502 (-4.3A);None;None;None;QRP A 502 (-4.3A)","1.48A","6b89A-3o2kA:0.0","5igyA-3o2kA:22.64"],["6B89_B_NOVB403_2","LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB","3o2k","BREVIANAMIDE F PRENYLTRANSFERASE","Aspergillus fumigatus",5,"LEU A  96;ALA A 434;PRO A 362;SER A 298;PHE A 280","QRP A 502 (-4.3A);None;None;None;QRP A 502 (-4.3A)","1.43A","6b89B-3o2kA:undetectable","6b89A-3o2kA:10.89"]]