SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'QNB'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 8 ASP A 103
SER A 107
SER A 433
LEU A  33
 QNB  A1162 (-3.1A)
QNB  A1162 (-3.4A)
None
None
 1.04A 3m0wE-3uonA:
undetectable
3m0wF-3uonA:
undetectable
3m0wG-3uonA:
undetectable
3m0wH-3uonA:
undetectable		 3m0wE-3uonA:
12.97
3m0wF-3uonA:
12.97
3m0wG-3uonA:
12.97
3m0wH-3uonA:
12.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RZE_A_D7VA1201_1
(HISTAMINE H1
RECEPTOR, LYSOZYME
CHIMERA)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A 103
TYR A 104
SER A 107
TRP A 155
TRP A 400
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-3.4A)
QNB  A1162 (-4.2A)
QNB  A1162 (-4.7A)
 1.13A 3rzeA-3uonA:
34.4		 3rzeA-3uonA:
58.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RZE_A_D7VA1201_1
(HISTAMINE H1
RECEPTOR, LYSOZYME
CHIMERA)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
SER A 107
TRP A 155
TYR A 403
TYR A 430
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-3.4A)
QNB  A1162 (-4.2A)
QNB  A1162 (-3.9A)
QNB  A1162 ( 4.8A)
 0.79A 3rzeA-3uonA:
34.4		 3rzeA-3uonA:
58.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A 103
TYR A 104
ALA A 191
TYR A 426
CYH A 429
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-3.9A)
QNB  A1162 ( 4.2A)
QNB  A1162 ( 4.0A)
 1.49A 4dajA-3uonA:
39.6		 4dajA-3uonA:
73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 ASP A 103
TYR A 104
SER A 107
ASN A 108
TRP A 155
THR A 187
ALA A 194
TRP A 400
TYR A 403
ASN A 404
CYH A 429
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-3.4A)
QNB  A1162 (-4.9A)
QNB  A1162 (-4.2A)
QNB  A1162 (-4.8A)
QNB  A1162 ( 4.0A)
QNB  A1162 (-4.7A)
QNB  A1162 (-3.9A)
QNB  A1162 (-2.9A)
QNB  A1162 ( 4.0A)
 0.59A 4dajA-3uonA:
39.6		 4dajA-3uonA:
73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 ASP A 103
TYR A 104
SER A 107
TRP A 155
THR A 187
ALA A 194
TRP A 400
TYR A 403
ASN A 404
TYR A 426
CYH A 429
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-3.4A)
QNB  A1162 (-4.2A)
QNB  A1162 (-4.8A)
QNB  A1162 ( 4.0A)
QNB  A1162 (-4.7A)
QNB  A1162 (-3.9A)
QNB  A1162 (-2.9A)
QNB  A1162 ( 4.2A)
QNB  A1162 ( 4.0A)
 0.74A 4dajA-3uonA:
39.6		 4dajA-3uonA:
73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
THR A 190
TRP A 400
ASN A 404
CYH A 429
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-4.3A)
QNB  A1162 (-4.7A)
QNB  A1162 (-2.9A)
QNB  A1162 ( 4.0A)
 1.45A 4dajA-3uonA:
39.6		 4dajA-3uonA:
73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A 103
TYR A 104
ALA A 191
TYR A 426
CYH A 429
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-3.9A)
QNB  A1162 ( 4.2A)
QNB  A1162 ( 4.0A)
 1.40A 4dajB-3uonA:
39.8		 4dajB-3uonA:
73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		12 / 12 ASP A 103
TYR A 104
SER A 107
TRP A 155
THR A 187
THR A 190
ALA A 194
TRP A 400
TYR A 403
ASN A 404
TYR A 426
CYH A 429
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-3.4A)
QNB  A1162 (-4.2A)
QNB  A1162 (-4.8A)
QNB  A1162 (-4.3A)
QNB  A1162 ( 4.0A)
QNB  A1162 (-4.7A)
QNB  A1162 (-3.9A)
QNB  A1162 (-2.9A)
QNB  A1162 ( 4.2A)
QNB  A1162 ( 4.0A)
 0.75A 4dajB-3uonA:
39.8		 4dajB-3uonA:
73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A 103
TYR A 104
THR A 187
ALA A 191
CYH A 429
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-4.8A)
QNB  A1162 (-3.9A)
QNB  A1162 ( 4.0A)
 1.29A 4dajB-3uonA:
39.8		 4dajB-3uonA:
73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
THR A 190
TRP A 400
ASN A 404
CYH A 429
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-4.3A)
QNB  A1162 (-4.7A)
QNB  A1162 (-2.9A)
QNB  A1162 ( 4.0A)
 1.43A 4dajB-3uonA:
39.8		 4dajB-3uonA:
73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 ASP A 103
TYR A 104
SER A 107
ASN A 108
TRP A 155
THR A 187
THR A 190
TRP A 400
TYR A 403
ASN A 404
CYH A 429
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-3.4A)
QNB  A1162 (-4.9A)
QNB  A1162 (-4.2A)
QNB  A1162 (-4.8A)
QNB  A1162 (-4.3A)
QNB  A1162 (-4.7A)
QNB  A1162 (-3.9A)
QNB  A1162 (-2.9A)
QNB  A1162 ( 4.0A)
 0.75A 4dajC-3uonA:
39.6		 4dajC-3uonA:
73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 ASP A 103
TYR A 104
SER A 107
TRP A 155
THR A 187
THR A 190
TRP A 400
TYR A 403
ASN A 404
TYR A 426
CYH A 429
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-3.4A)
QNB  A1162 (-4.2A)
QNB  A1162 (-4.8A)
QNB  A1162 (-4.3A)
QNB  A1162 (-4.7A)
QNB  A1162 (-3.9A)
QNB  A1162 (-2.9A)
QNB  A1162 ( 4.2A)
QNB  A1162 ( 4.0A)
 0.85A 4dajC-3uonA:
39.6		 4dajC-3uonA:
73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_D_0HKD2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 ASP A 103
TYR A 104
SER A 107
ASN A 108
TRP A 155
THR A 187
THR A 190
TRP A 400
TYR A 403
ASN A 404
CYH A 429
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-3.4A)
QNB  A1162 (-4.9A)
QNB  A1162 (-4.2A)
QNB  A1162 (-4.8A)
QNB  A1162 (-4.3A)
QNB  A1162 (-4.7A)
QNB  A1162 (-3.9A)
QNB  A1162 (-2.9A)
QNB  A1162 ( 4.0A)
 0.62A 4dajD-3uonA:
39.6		 4dajD-3uonA:
73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_D_0HKD2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 ASP A 103
TYR A 104
SER A 107
TRP A 155
THR A 187
THR A 190
TRP A 400
TYR A 403
ASN A 404
TYR A 426
CYH A 429
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-3.4A)
QNB  A1162 (-4.2A)
QNB  A1162 (-4.8A)
QNB  A1162 (-4.3A)
QNB  A1162 (-4.7A)
QNB  A1162 (-3.9A)
QNB  A1162 (-2.9A)
QNB  A1162 ( 4.2A)
QNB  A1162 ( 4.0A)
 0.76A 4dajD-3uonA:
39.6		 4dajD-3uonA:
73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_D_0HKD2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
THR A 190
TRP A 400
ASN A 404
CYH A 429
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-4.3A)
QNB  A1162 (-4.7A)
QNB  A1162 (-2.9A)
QNB  A1162 ( 4.0A)
 1.48A 4dajD-3uonA:
39.6		 4dajD-3uonA:
73.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 LEU A 100
ASP A 103
SER A 107
PHE A 181
ALA A 194
TRP A 400
 None
QNB  A1162 (-3.1A)
QNB  A1162 (-3.4A)
QNB  A1162 (-4.4A)
QNB  A1162 ( 4.0A)
QNB  A1162 (-4.7A)
 1.24A 4nc3A-3uonA:
27.0		 4nc3A-3uonA:
28.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		3 / 3 ASP A 103
TYR A 104
TRP A  99
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
None
 1.38A 4p7nA-3uonA:
undetectable		 4p7nA-3uonA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_C_377C401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 6 TYR A 403
ASN A 404
TYR A 104
PHE A 181
 QNB  A1162 (-3.9A)
QNB  A1162 (-2.9A)
QNB  A1162 (-4.0A)
QNB  A1162 (-4.4A)
 1.26A 4twdB-3uonA:
2.7
4twdC-3uonA:
2.7		 4twdB-3uonA:
19.33
4twdC-3uonA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_C_377C402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 5 TYR A 403
ASN A 404
TYR A 104
PHE A 181
 QNB  A1162 (-3.9A)
QNB  A1162 (-2.9A)
QNB  A1162 (-4.0A)
QNB  A1162 (-4.4A)
 1.31A 4twdC-3uonA:
2.7
4twdD-3uonA:
2.8		 4twdC-3uonA:
19.33
4twdD-3uonA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_H_377H401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 6 TYR A 403
ASN A 404
TYR A 104
PHE A 181
 QNB  A1162 (-3.9A)
QNB  A1162 (-2.9A)
QNB  A1162 (-4.0A)
QNB  A1162 (-4.4A)
 1.32A 4twdG-3uonA:
undetectable
4twdH-3uonA:
1.7		 4twdG-3uonA:
19.33
4twdH-3uonA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_J_377J401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 6 TYR A 403
ASN A 404
TYR A 104
PHE A 181
 QNB  A1162 (-3.9A)
QNB  A1162 (-2.9A)
QNB  A1162 (-4.0A)
QNB  A1162 (-4.4A)
 1.31A 4twdI-3uonA:
undetectable
4twdJ-3uonA:
undetectable		 4twdI-3uonA:
19.33
4twdJ-3uonA:
19.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A 103
TYR A 104
ALA A 191
TYR A 426
CYH A 429
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-3.9A)
QNB  A1162 ( 4.2A)
QNB  A1162 ( 4.0A)
 1.49A 4u14A-3uonA:
38.6		 4u14A-3uonA:
73.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		12 / 12 ILE A  72
ASP A 103
TYR A 104
SER A 107
TRP A 155
THR A 187
ALA A 191
ALA A 194
TRP A 400
ASN A 404
TYR A 426
CYH A 429
 None
QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-3.4A)
QNB  A1162 (-4.2A)
QNB  A1162 (-4.8A)
QNB  A1162 (-3.9A)
QNB  A1162 ( 4.0A)
QNB  A1162 (-4.7A)
QNB  A1162 (-2.9A)
QNB  A1162 ( 4.2A)
QNB  A1162 ( 4.0A)
 0.91A 4u14A-3uonA:
38.6		 4u14A-3uonA:
73.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 ILE A  72
ASP A 103
TYR A 104
THR A 190
TRP A 400
ASN A 404
CYH A 429
 None
QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-4.3A)
QNB  A1162 (-4.7A)
QNB  A1162 (-2.9A)
QNB  A1162 ( 4.0A)
 1.43A 4u14A-3uonA:
38.6		 4u14A-3uonA:
73.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ILE A  72
TYR A 104
THR A 190
ALA A 194
TRP A 400
CYH A 429
 None
QNB  A1162 (-4.0A)
QNB  A1162 (-4.3A)
QNB  A1162 ( 4.0A)
QNB  A1162 (-4.7A)
QNB  A1162 ( 4.0A)
 1.49A 4u14A-3uonA:
38.6		 4u14A-3uonA:
73.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		12 / 12 ASP A 103
TYR A 104
SER A 107
TRP A 155
THR A 187
THR A 190
ALA A 191
ALA A 194
TRP A 400
ASN A 404
TYR A 426
CYH A 429
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-3.4A)
QNB  A1162 (-4.2A)
QNB  A1162 (-4.8A)
QNB  A1162 (-4.3A)
QNB  A1162 (-3.9A)
QNB  A1162 ( 4.0A)
QNB  A1162 (-4.7A)
QNB  A1162 (-2.9A)
QNB  A1162 ( 4.2A)
QNB  A1162 ( 4.0A)
 0.79A 4u15A-3uonA:
39.0		 4u15A-3uonA:
65.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A 103
TYR A 104
THR A 187
ALA A 191
CYH A 429
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-4.8A)
QNB  A1162 (-3.9A)
QNB  A1162 ( 4.0A)
 1.23A 4u15A-3uonA:
39.0		 4u15A-3uonA:
65.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
THR A 190
TRP A 400
ASN A 404
CYH A 429
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-4.3A)
QNB  A1162 (-4.7A)
QNB  A1162 (-2.9A)
QNB  A1162 ( 4.0A)
 1.43A 4u15A-3uonA:
39.0		 4u15A-3uonA:
65.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 TYR A 104
SER A 107
TRP A 155
TRP A 400
TYR A 403
CYH A 429
 QNB  A1162 (-4.0A)
QNB  A1162 (-3.4A)
QNB  A1162 (-4.2A)
QNB  A1162 (-4.7A)
QNB  A1162 (-3.9A)
QNB  A1162 ( 4.0A)
 1.47A 4u15A-3uonA:
39.0		 4u15A-3uonA:
65.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		3 / 3 ASN A 108
PHE A 195
TYR A 403
 QNB  A1162 (-4.9A)
QNB  A1162 (-4.4A)
QNB  A1162 (-3.9A)
 0.53A 4u15A-3uonA:
39.0		 4u15A-3uonA:
65.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 ASP A 103
TYR A 104
SER A 107
THR A 187
THR A 190
ALA A 191
ALA A 194
TRP A 400
TYR A 403
ASN A 404
CYH A 429
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-3.4A)
QNB  A1162 (-4.8A)
QNB  A1162 (-4.3A)
QNB  A1162 (-3.9A)
QNB  A1162 ( 4.0A)
QNB  A1162 (-4.7A)
QNB  A1162 (-3.9A)
QNB  A1162 (-2.9A)
QNB  A1162 ( 4.0A)
 0.52A 4u15B-3uonA:
19.2		 4u15B-3uonA:
65.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A 103
TYR A 104
THR A 187
ALA A 191
CYH A 429
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-4.8A)
QNB  A1162 (-3.9A)
QNB  A1162 ( 4.0A)
 1.25A 4u15B-3uonA:
19.2		 4u15B-3uonA:
65.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 TYR A 104
SER A 107
THR A 187
THR A 190
ALA A 191
ALA A 194
TRP A 400
TYR A 403
ASN A 404
TYR A 426
CYH A 429
 QNB  A1162 (-4.0A)
QNB  A1162 (-3.4A)
QNB  A1162 (-4.8A)
QNB  A1162 (-4.3A)
QNB  A1162 (-3.9A)
QNB  A1162 ( 4.0A)
QNB  A1162 (-4.7A)
QNB  A1162 (-3.9A)
QNB  A1162 (-2.9A)
QNB  A1162 ( 4.2A)
QNB  A1162 ( 4.0A)
 0.73A 4u15B-3uonA:
19.2		 4u15B-3uonA:
65.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CXV_A_0HKA501_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A 103
TYR A 104
ALA A 191
TYR A 426
CYH A 429
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-3.9A)
QNB  A1162 ( 4.2A)
QNB  A1162 ( 4.0A)
 1.40A 5cxvA-3uonA:
39.7		 5cxvA-3uonA:
68.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CXV_A_0HKA501_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 ASP A 103
TYR A 104
SER A 107
TRP A 155
ALA A 191
ALA A 194
TRP A 400
TYR A 403
ASN A 404
TYR A 426
CYH A 429
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-3.4A)
QNB  A1162 (-4.2A)
QNB  A1162 (-3.9A)
QNB  A1162 ( 4.0A)
QNB  A1162 (-4.7A)
QNB  A1162 (-3.9A)
QNB  A1162 (-2.9A)
QNB  A1162 ( 4.2A)
QNB  A1162 ( 4.0A)
 0.74A 5cxvA-3uonA:
39.7		 5cxvA-3uonA:
68.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		3 / 3 THR A 187
THR A 190
PHE A 195
 QNB  A1162 (-4.8A)
QNB  A1162 (-4.3A)
QNB  A1162 (-4.4A)
 0.51A 5cxvA-3uonA:
39.7		 5cxvA-3uonA:
68.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ASP A 103
TYR A 104
SER A 107
THR A 187
TRP A 400
CYH A 429
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-3.4A)
QNB  A1162 (-4.8A)
QNB  A1162 (-4.7A)
QNB  A1162 ( 4.0A)
 1.39A 5dsgA-3uonA:
39.7		 5dsgA-3uonA:
76.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		10 / 12 ASP A 103
TYR A 104
SER A 107
TRP A 155
THR A 187
THR A 190
TRP A 400
TYR A 403
TYR A 426
CYH A 429
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-3.4A)
QNB  A1162 (-4.2A)
QNB  A1162 (-4.8A)
QNB  A1162 (-4.3A)
QNB  A1162 (-4.7A)
QNB  A1162 (-3.9A)
QNB  A1162 ( 4.2A)
QNB  A1162 ( 4.0A)
 0.91A 5dsgA-3uonA:
39.7		 5dsgA-3uonA:
76.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A 103
TYR A 104
THR A 187
ALA A 191
CYH A 429
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-4.8A)
QNB  A1162 (-3.9A)
QNB  A1162 ( 4.0A)
 1.37A 5dsgA-3uonA:
39.7		 5dsgA-3uonA:
76.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 TYR A 104
SER A 107
THR A 187
TRP A 400
ASN A 404
CYH A 429
 QNB  A1162 (-4.0A)
QNB  A1162 (-3.4A)
QNB  A1162 (-4.8A)
QNB  A1162 (-4.7A)
QNB  A1162 (-2.9A)
QNB  A1162 ( 4.0A)
 1.47A 5dsgA-3uonA:
39.7		 5dsgA-3uonA:
76.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 TYR A 104
SER A 107
TRP A 155
THR A 187
THR A 190
ALA A 194
TRP A 400
TYR A 403
ASN A 404
TYR A 426
CYH A 429
 QNB  A1162 (-4.0A)
QNB  A1162 (-3.4A)
QNB  A1162 (-4.2A)
QNB  A1162 (-4.8A)
QNB  A1162 (-4.3A)
QNB  A1162 ( 4.0A)
QNB  A1162 (-4.7A)
QNB  A1162 (-3.9A)
QNB  A1162 (-2.9A)
QNB  A1162 ( 4.2A)
QNB  A1162 ( 4.0A)
 0.75A 5dsgA-3uonA:
39.7		 5dsgA-3uonA:
76.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 TYR A 104
SER A 107
THR A 187
TRP A 400
ASN A 404
CYH A 429
 QNB  A1162 (-4.0A)
QNB  A1162 (-3.4A)
QNB  A1162 (-4.8A)
QNB  A1162 (-4.7A)
QNB  A1162 (-2.9A)
QNB  A1162 ( 4.0A)
 1.48A 5dsgB-3uonA:
38.3		 5dsgB-3uonA:
76.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 TYR A 104
SER A 107
TRP A 155
THR A 187
THR A 190
ALA A 194
TRP A 400
TYR A 403
ASN A 404
TYR A 426
CYH A 429
 QNB  A1162 (-4.0A)
QNB  A1162 (-3.4A)
QNB  A1162 (-4.2A)
QNB  A1162 (-4.8A)
QNB  A1162 (-4.3A)
QNB  A1162 ( 4.0A)
QNB  A1162 (-4.7A)
QNB  A1162 (-3.9A)
QNB  A1162 (-2.9A)
QNB  A1162 ( 4.2A)
QNB  A1162 ( 4.0A)
 0.73A 5dsgB-3uonA:
38.3		 5dsgB-3uonA:
76.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 TRP A  99
LEU A 100
SER A 107
PHE A 181
ALA A 194
 None
None
QNB  A1162 (-3.4A)
QNB  A1162 (-4.4A)
QNB  A1162 ( 4.0A)
 0.99A 6drxA-3uonA:
26.7		 6drxA-3uonA:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 TRP A  99
LEU A 100
SER A 107
PHE A 181
TRP A 400
 None
None
QNB  A1162 (-3.4A)
QNB  A1162 (-4.4A)
QNB  A1162 (-4.7A)
 1.31A 6drxA-3uonA:
26.7		 6drxA-3uonA:
27.97