SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'QHF'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		4 / 5 HIS A 149
GLU A 150
HIS A 153
HIS A 159
 ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
 0.19A 1os2A-3q2hA:
10.4		 1os2A-3q2hA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		4 / 4 HIS A 149
GLU A 150
HIS A 153
HIS A 159
 ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
 0.17A 1os2D-3q2hA:
10.5		 1os2D-3q2hA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R55_A_097A518_1
(ADAM 33)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		6 / 10 THR A 117
THR A 146
HIS A 149
GLU A 150
HIS A 153
HIS A 159
 QHF  A   1 ( 4.0A)
QHF  A   1 (-4.4A)
ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
 0.29A 1r55A-3q2hA:
25.6		 1r55A-3q2hA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		4 / 4 HIS A 149
GLU A 150
HIS A 153
HIS A 159
 ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
 0.21A 1uttA-3q2hA:
10.9		 1uttA-3q2hA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		4 / 4 HIS A 149
GLU A 150
HIS A 153
HIS A 159
 ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
 0.17A 1utzA-3q2hA:
10.6		 1utzA-3q2hA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		4 / 4 HIS A 149
GLU A 150
HIS A 153
HIS A 159
 ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
 0.20A 1utzB-3q2hA:
10.7		 1utzB-3q2hA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		4 / 6 HIS A 149
GLU A 150
HIS A 153
HIS A 159
 ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
 0.19A 1y93A-3q2hA:
10.7		 1y93A-3q2hA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		4 / 4 HIS A 149
GLU A 150
HIS A 153
HIS A 159
 ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
 0.15A 2hu6A-3q2hA:
10.7		 2hu6A-3q2hA:
18.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JIH_A_097A1001_1
(ADAMTS-1)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		8 / 9 ASP A 116
LEU A 118
THR A 146
HIS A 149
GLU A 150
HIS A 153
HIS A 159
MET A 181
 None
QHF  A   1 (-4.5A)
QHF  A   1 (-4.4A)
ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
None
 0.77A 2jihA-3q2hA:
47.4		 2jihA-3q2hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JIH_A_097A1001_1
(ADAMTS-1)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		8 / 9 LEU A 118
THR A 146
HIS A 149
GLU A 150
HIS A 153
HIS A 159
MET A 181
LEU A 182
 QHF  A   1 (-4.5A)
QHF  A   1 (-4.4A)
ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
None
QHF  A   1 (-4.7A)
 0.76A 2jihA-3q2hA:
47.4		 2jihA-3q2hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JIH_B_097B1001_1
(ADAMTS-1)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		7 / 8 ASP A 116
LEU A 118
THR A 146
HIS A 149
GLU A 150
HIS A 153
HIS A 159
 None
QHF  A   1 (-4.5A)
QHF  A   1 (-4.4A)
ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
 0.36A 2jihB-3q2hA:
46.3		 2jihB-3q2hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JIH_B_097B1001_1
(ADAMTS-1)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		7 / 8 LEU A 118
THR A 146
HIS A 149
GLU A 150
HIS A 153
HIS A 159
LEU A 182
 QHF  A   1 (-4.5A)
QHF  A   1 (-4.4A)
ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
QHF  A   1 (-4.7A)
 0.51A 2jihB-3q2hA:
46.3		 2jihB-3q2hA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		4 / 6 HIS A 149
GLU A 150
HIS A 153
HIS A 159
 ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
 0.23A 2ow9A-3q2hA:
10.4		 2ow9A-3q2hA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		4 / 4 HIS A 149
GLU A 150
HIS A 153
HIS A 159
 ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
 0.20A 2ow9B-3q2hA:
10.3		 2ow9B-3q2hA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		4 / 4 HIS A 149
GLU A 150
HIS A 153
HIS A 159
 ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
 0.25A 2ozrC-3q2hA:
10.1		 2ozrC-3q2hA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		4 / 4 HIS A 149
GLU A 150
HIS A 153
HIS A 159
 ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
 0.21A 2ozrD-3q2hA:
10.1		 2ozrD-3q2hA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		4 / 4 HIS A 149
GLU A 150
HIS A 153
HIS A 159
 ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
 0.27A 2ozrE-3q2hA:
10.1		 2ozrE-3q2hA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		3 / 3 HIS A 149
HIS A 153
HIS A 159
 ZN  A 401 ( 3.3A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
 0.24A 2ozrF-3q2hA:
10.1		 2ozrF-3q2hA:
20.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		8 / 9 ASP A 116
LEU A 118
THR A 146
HIS A 149
GLU A 150
HIS A 153
HIS A 159
LEU A 182
 None
QHF  A   1 (-4.5A)
QHF  A   1 (-4.4A)
ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
QHF  A   1 (-4.7A)
 0.48A 3hy7A-3q2hA:
35.2		 3hy7A-3q2hA:
57.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		8 / 9 ASP A 116
LEU A 118
THR A 146
HIS A 149
GLU A 150
HIS A 153
HIS A 159
LEU A 182
 None
QHF  A   1 (-4.5A)
QHF  A   1 (-4.4A)
ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
QHF  A   1 (-4.7A)
 0.59A 3hy7B-3q2hA:
33.7		 3hy7B-3q2hA:
57.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		4 / 5 HIS A 149
GLU A 150
HIS A 153
HIS A 159
 ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
 0.20A 3kecA-3q2hA:
10.4		 3kecA-3q2hA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		3 / 3 HIS A 149
GLU A 150
HIS A 153
 ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
 0.22A 3kecB-3q2hA:
10.3		 3kecB-3q2hA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		4 / 5 HIS A 149
GLU A 150
HIS A 153
HIS A 159
 ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
 0.20A 3likA-3q2hA:
10.8		 3likA-3q2hA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		4 / 4 HIS A 149
GLU A 150
HIS A 153
HIS A 159
 ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
 0.21A 3lilA-3q2hA:
10.8		 3lilA-3q2hA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		4 / 5 HIS A 149
GLU A 150
HIS A 153
HIS A 159
 ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
 0.21A 3ljgA-3q2hA:
10.8		 3ljgA-3q2hA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		4 / 5 HIS A 149
GLU A 150
HIS A 153
HIS A 159
 ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
 0.16A 3lkaA-3q2hA:
10.7		 3lkaA-3q2hA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		4 / 6 HIS A 149
GLU A 150
HIS A 153
HIS A 159
 ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
 0.31A 4a7bA-3q2hA:
10.1		 4a7bA-3q2hA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_A_T3A1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		5 / 12 PHE A 155
GLY A 124
VAL A 123
SER A 195
TRP A 191
 None
None
QHF  A   1 (-4.7A)
None
None
 1.13A 4bvaA-3q2hA:
undetectable		 4bvaA-3q2hA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		4 / 4 HIS A 149
GLU A 150
HIS A 153
HIS A 159
 ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
 0.17A 5n5jA-3q2hA:
10.7		 5n5jA-3q2hA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		4 / 5 HIS A 149
GLU A 150
HIS A 153
HIS A 159
 ZN  A 401 ( 3.3A)
QHF  A   1 (-2.6A)
QHF  A   1 ( 3.0A)
ZN  A 401 ( 3.2A)
 0.17A 5n5kA-3q2hA:
10.8		 5n5kA-3q2hA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		4 / 8 HIS A 153
PHE A 155
SER A 132
LEU A 211
 QHF  A   1 ( 3.0A)
None
None
None
 1.06A 5y2tB-3q2hA:
undetectable		 5y2tB-3q2hA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		5 / 12 THR A 117
THR A 146
THR A 147
ALA A 143
THR A  76
 QHF  A   1 ( 4.0A)
QHF  A   1 (-4.4A)
None
None
None
 1.25A 6hwdV-3q2hA:
undetectable
6hwdb-3q2hA:
undetectable		 6hwdV-3q2hA:
14.14
6hwdb-3q2hA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1
(Homo
sapiens) 		5 / 12 THR A 117
THR A 146
THR A 147
ALA A 143
THR A  76
 QHF  A   1 ( 4.0A)
QHF  A   1 (-4.4A)
None
None
None
 1.25A 6hwdH-3q2hA:
undetectable
6hwdN-3q2hA:
undetectable		 6hwdH-3q2hA:
14.14
6hwdN-3q2hA:
20.62