SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'Q9C'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C3S_A_SHHA952_1
(HDLP (HISTONE
DEACETYLASE-LIKE
PROTEIN))		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		6 / 11 HIS A 158
ASP A 195
HIS A 197
PHE A 225
ASP A 284
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
None
 0.44A 1c3sA-3q9cA:
36.9		 1c3sA-3q9cA:
27.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ISM_B_NCAB305_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		4 / 7 HIS A 158
LEU A 281
SER A 280
ASP A 193
 Q9C  A 401 (-4.2A)
None
None
K  A 342 (-3.2A)
 1.04A 1ismB-3q9cA:
undetectable		 1ismB-3q9cA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		6 / 12 HIS A 158
THR A 285
GLY A 282
GLU A 320
GLY A 321
HIS A 197
 Q9C  A 401 (-4.2A)
None
None
None
Q9C  A 401 (-3.6A)
ZN  A 343 (-3.4A)
 1.40A 1n2xB-3q9cA:
3.9		 1n2xB-3q9cA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T69_A_SHHA379_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		7 / 12 HIS A 158
GLY A 167
ASP A 195
HIS A 197
PHE A 225
ASP A 284
TYR A 323
 Q9C  A 401 (-4.2A)
Q9C  A 401 (-3.7A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
None
 0.45A 1t69A-3q9cA:
35.6		 1t69A-3q9cA:
25.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		7 / 11 HIS A 158
ASP A 195
HIS A 197
PHE A 225
ASP A 284
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
Q9C  A 401 (-3.6A)
None
 0.39A 1zz1A-3q9cA:
41.9		 1zz1A-3q9cA:
29.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 11 HIS A 158
HIS A 197
ASP A 284
GLY A 322
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 1.25A 1zz1A-3q9cA:
41.9		 1zz1A-3q9cA:
29.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_B_SHHB2552_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		7 / 12 HIS A 158
ASP A 195
HIS A 197
PHE A 225
ASP A 284
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
Q9C  A 401 (-3.6A)
None
 0.38A 1zz1B-3q9cA:
42.3
1zz1C-3q9cA:
42.1		 1zz1B-3q9cA:
29.89
1zz1C-3q9cA:
29.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_C_SHHC2652_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		8 / 12 HIS A 158
GLY A 167
ASP A 195
HIS A 197
PHE A 225
ASP A 284
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
Q9C  A 401 (-3.7A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
Q9C  A 401 (-3.6A)
None
 0.42A 1zz1C-3q9cA:
42.1		 1zz1C-3q9cA:
29.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_D_SHHD2752_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		6 / 9 HIS A 158
ASP A 195
HIS A 197
PHE A 225
ASP A 284
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
None
 0.40A 1zz1D-3q9cA:
41.9		 1zz1D-3q9cA:
29.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_0
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 GLY A 157
TYR A 168
GLY A 321
ILE A 171
ALA A 160
 None
Q9C  A 401 (-3.7A)
Q9C  A 401 (-3.6A)
None
None
 1.11A 2plwA-3q9cA:
2.2		 2plwA-3q9cA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_A_SHHA301_1
(HISTONE DEACETYLASE
7A)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		4 / 5 HIS A 158
ASP A 195
HIS A 197
ASP A 284
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
 0.16A 3c0zA-3q9cA:
39.4		 3c0zA-3q9cA:
25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		4 / 8 HIS A 158
ASP A 195
ASP A 284
GLY A 282
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-2.7A)
None
 0.90A 3c0zB-3q9cA:
39.3		 3c0zB-3q9cA:
25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		6 / 8 HIS A 158
ASP A 195
HIS A 197
PHE A 225
ASP A 284
GLY A 321
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
Q9C  A 401 (-3.6A)
 0.29A 3c0zB-3q9cA:
39.3		 3c0zB-3q9cA:
25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		4 / 6 HIS A 158
ASP A 195
HIS A 197
ASP A 284
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
 0.23A 3c0zC-3q9cA:
39.3		 3c0zC-3q9cA:
25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 ASN A 173
ALA A 127
ALA A  33
GLY A 321
THR A 118
 None
None
None
Q9C  A 401 (-3.6A)
None
 0.93A 3c6gA-3q9cA:
undetectable		 3c6gA-3q9cA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_1
(CYTOCHROME P450 2R1)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		4 / 5 ASN A 173
ALA A  33
GLY A 321
THR A 118
 None
None
Q9C  A 401 (-3.6A)
None
 0.82A 3dl9A-3q9cA:
undetectable		 3dl9A-3q9cA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_A_SHHA700_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		7 / 10 HIS A 158
ASP A 195
HIS A 197
ASP A 284
PRO A 290
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
Q9C  A 401 (-3.6A)
None
 0.53A 4bz6A-3q9cA:
35.5		 4bz6A-3q9cA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_A_SHHA700_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 10 HIS A 158
HIS A 197
ASP A 284
GLY A 322
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 1.24A 4bz6A-3q9cA:
35.5		 4bz6A-3q9cA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_A_SHHA700_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 10 HIS A 158
HIS A 197
ASP A 284
PRO A 290
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 0.95A 4bz6A-3q9cA:
35.5		 4bz6A-3q9cA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_B_SHHB700_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		8 / 12 HIS A 158
ASP A 195
HIS A 197
PHE A 225
ASP A 284
PRO A 290
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
None
Q9C  A 401 (-3.6A)
None
 0.62A 4bz6A-3q9cA:
35.4
4bz6B-3q9cA:
35.3		 4bz6A-3q9cA:
22.01
4bz6B-3q9cA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_B_SHHB700_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A 158
HIS A 197
ASP A 284
GLY A 322
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 1.22A 4bz6A-3q9cA:
35.4
4bz6B-3q9cA:
35.3		 4bz6A-3q9cA:
22.01
4bz6B-3q9cA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_B_SHHB700_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A 158
HIS A 197
ASP A 284
PRO A 290
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 0.97A 4bz6A-3q9cA:
35.4
4bz6B-3q9cA:
35.3		 4bz6A-3q9cA:
22.01
4bz6B-3q9cA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		9 / 12 HIS A 158
GLY A 167
ASP A 195
HIS A 197
PHE A 225
ASP A 284
PRO A 290
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
Q9C  A 401 (-3.7A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
None
Q9C  A 401 (-3.6A)
None
 0.65A 4bz6C-3q9cA:
35.4		 4bz6C-3q9cA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A 158
HIS A 197
ASP A 284
GLY A 322
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 1.22A 4bz6C-3q9cA:
35.4		 4bz6C-3q9cA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A 158
HIS A 197
ASP A 284
PRO A 290
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 0.96A 4bz6C-3q9cA:
35.4		 4bz6C-3q9cA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_D_SHHD700_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		7 / 10 HIS A 158
ASP A 195
HIS A 197
ASP A 284
PRO A 290
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
Q9C  A 401 (-3.6A)
None
 0.55A 4bz6D-3q9cA:
35.4		 4bz6D-3q9cA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_D_SHHD700_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 10 HIS A 158
HIS A 197
ASP A 284
GLY A 322
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 1.24A 4bz6D-3q9cA:
35.4		 4bz6D-3q9cA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_D_SHHD700_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 10 HIS A 158
HIS A 197
ASP A 284
PRO A 290
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 0.98A 4bz6D-3q9cA:
35.4		 4bz6D-3q9cA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		7 / 12 HIS A 158
GLY A 167
ASP A 195
HIS A 197
ASP A 284
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
Q9C  A 401 (-3.7A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
Q9C  A 401 (-3.6A)
None
 0.36A 4lxzA-3q9cA:
38.2		 4lxzA-3q9cA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A 158
HIS A 197
ASP A 284
GLY A 322
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 1.21A 4lxzA-3q9cA:
38.2		 4lxzA-3q9cA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		6 / 11 HIS A 158
ASP A 195
HIS A 197
ASP A 284
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
Q9C  A 401 (-3.6A)
None
 0.34A 4lxzB-3q9cA:
38.1		 4lxzB-3q9cA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 11 HIS A 158
HIS A 197
ASP A 284
GLY A 322
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 1.21A 4lxzB-3q9cA:
38.1		 4lxzB-3q9cA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		8 / 12 HIS A 158
GLY A 167
ASP A 195
HIS A 197
PHE A 225
ASP A 284
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
Q9C  A 401 (-3.7A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
Q9C  A 401 (-3.6A)
None
 0.43A 4lxzC-3q9cA:
38.2		 4lxzC-3q9cA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A 158
HIS A 197
ASP A 284
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
Q9C  A 401 (-3.6A)
None
 1.03A 4lxzC-3q9cA:
38.2		 4lxzC-3q9cA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		8 / 12 HIS A 158
GLY A 167
ASP A 195
HIS A 197
PHE A 225
ASP A 284
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
Q9C  A 401 (-3.7A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
Q9C  A 401 (-3.6A)
None
 0.43A 4qa0A-3q9cA:
35.8		 4qa0A-3q9cA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A 158
HIS A 197
ASP A 284
GLY A 322
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 1.24A 4qa0A-3q9cA:
35.8		 4qa0A-3q9cA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A 197
PHE A 225
ASP A 284
GLY A 322
TYR A 323
 ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
None
None
 1.32A 4qa0A-3q9cA:
35.8		 4qa0A-3q9cA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		7 / 11 HIS A 158
ASP A 195
HIS A 197
PHE A 225
ASP A 284
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
Q9C  A 401 (-3.6A)
None
 0.46A 4qa0B-3q9cA:
35.7		 4qa0B-3q9cA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 11 HIS A 158
HIS A 197
ASP A 284
GLY A 322
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 1.24A 4qa0B-3q9cA:
35.7		 4qa0B-3q9cA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 11 HIS A 197
PHE A 225
ASP A 284
GLY A 322
TYR A 323
 ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
None
None
 1.31A 4qa0B-3q9cA:
35.7		 4qa0B-3q9cA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		8 / 12 HIS A 158
GLY A 167
ASP A 195
HIS A 197
PHE A 225
ASP A 284
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
Q9C  A 401 (-3.7A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
Q9C  A 401 (-3.6A)
None
 0.49A 4qa2A-3q9cA:
35.2		 4qa2A-3q9cA:
25.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A 158
HIS A 197
ASP A 284
GLY A 322
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 1.24A 4qa2A-3q9cA:
35.2		 4qa2A-3q9cA:
25.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A 197
PHE A 225
ASP A 284
GLY A 322
TYR A 323
 ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
None
None
 1.31A 4qa2A-3q9cA:
35.2		 4qa2A-3q9cA:
25.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		8 / 12 HIS A 158
GLY A 167
ASP A 195
HIS A 197
PHE A 225
ASP A 284
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
Q9C  A 401 (-3.7A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
Q9C  A 401 (-3.6A)
None
 0.43A 4qa2B-3q9cA:
36.0		 4qa2B-3q9cA:
25.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A 158
HIS A 197
ASP A 284
GLY A 322
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 1.23A 4qa2B-3q9cA:
36.0		 4qa2B-3q9cA:
25.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_A_SHHA2004_1
(HDAC6 PROTEIN)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		7 / 12 HIS A 158
GLY A 167
ASP A 195
HIS A 197
PHE A 225
ASP A 284
TYR A 323
 Q9C  A 401 (-4.2A)
Q9C  A 401 (-3.7A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
None
 0.30A 5eeiA-3q9cA:
41.4		 5eeiA-3q9cA:
27.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_B_SHHB801_1
(HDAC6 PROTEIN)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		7 / 12 HIS A 158
GLY A 167
ASP A 195
HIS A 197
PHE A 225
ASP A 284
TYR A 323
 Q9C  A 401 (-4.2A)
Q9C  A 401 (-3.7A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
None
 0.31A 5eeiB-3q9cA:
41.2		 5eeiB-3q9cA:
27.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A 158
ASP A 195
HIS A 197
ASP A 284
GLY A 282
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
 1.28A 5eenA-3q9cA:
41.2		 5eenA-3q9cA:
27.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		7 / 12 HIS A 158
ASP A 195
HIS A 197
PHE A 225
ASP A 284
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
Q9C  A 401 (-3.6A)
None
 0.32A 5eenA-3q9cA:
41.2		 5eenA-3q9cA:
27.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A 158
HIS A 197
ASP A 284
GLY A 322
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 1.27A 5eenA-3q9cA:
41.2		 5eenA-3q9cA:
27.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEN_B_5OGB804_1
(HDAC6 PROTEIN)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		6 / 12 HIS A 158
ASP A 195
HIS A 197
PHE A 225
ASP A 284
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
None
 0.33A 5eenB-3q9cA:
41.2		 5eenB-3q9cA:
27.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF8_A_LBHA2004_1
(HDAC6 PROTEIN)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		6 / 12 HIS A 158
ASP A 195
HIS A 197
PHE A 225
ASP A 284
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
None
 0.27A 5ef8A-3q9cA:
41.4		 5ef8A-3q9cA:
27.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF8_B_LBHB2004_1
(HDAC6 PROTEIN)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		6 / 12 HIS A 158
ASP A 195
HIS A 197
PHE A 225
ASP A 284
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
None
 0.29A 5ef8B-3q9cA:
41.3		 5ef8B-3q9cA:
27.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 ILE A 291
ASP A 195
HIS A 197
GLU A 320
ILE A 328
 Q9C  A 401 ( 4.4A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
None
None
 1.43A 5igwA-3q9cA:
undetectable		 5igwA-3q9cA:
22.68