SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'PVG'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1V_A_H4BA700_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.13A 1d1vA-3vv4A:
undetectable
1d1vB-3vv4A:
undetectable		 1d1vA-3vv4A:
19.91
1d1vB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1V_B_H4BB701_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.13A 1d1vA-3vv4A:
undetectable
1d1vB-3vv4A:
undetectable		 1d1vA-3vv4A:
19.91
1d1vB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1W_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.12A 1d1wA-3vv4A:
undetectable
1d1wB-3vv4A:
undetectable		 1d1wA-3vv4A:
19.91
1d1wB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1W_B_H4BB601_1
(NITRIC OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.14A 1d1wA-3vv4A:
undetectable
1d1wB-3vv4A:
undetectable		 1d1wA-3vv4A:
19.91
1d1wB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1X_A_H4BA600_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME DOMAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.12A 1d1xA-3vv4A:
undetectable
1d1xB-3vv4A:
undetectable		 1d1xA-3vv4A:
19.91
1d1xB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1X_B_H4BB601_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME DOMAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.13A 1d1xA-3vv4A:
0.0
1d1xB-3vv4A:
0.0		 1d1xA-3vv4A:
19.91
1d1xB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DM8_A_H4BA1600_1
(NITRIC OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.13A 1dm8A-3vv4A:
undetectable
1dm8B-3vv4A:
undetectable		 1dm8A-3vv4A:
19.91
1dm8B-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DM8_B_H4BB2600_1
(NITRIC OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.14A 1dm8A-3vv4A:
undetectable
1dm8B-3vv4A:
undetectable		 1dm8A-3vv4A:
19.91
1dm8B-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_B_BHSB2610_1
(NITRIC OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.13A 1dmiA-3vv4A:
undetectable
1dmiB-3vv4A:
undetectable		 1dmiA-3vv4A:
19.91
1dmiB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOP_A_H4BA1600_1
(NITRIC-OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.07A 1fopA-3vv4A:
undetectable
1fopB-3vv4A:
undetectable		 1fopA-3vv4A:
19.91
1fopB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOP_B_H4BB2600_1
(NITRIC-OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.12A 1fopA-3vv4A:
undetectable
1fopB-3vv4A:
undetectable		 1fopA-3vv4A:
19.91
1fopB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.10A 1nseA-3vv4A:
undetectable
1nseB-3vv4A:
undetectable		 1nseA-3vv4A:
19.91
1nseB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSE_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.11A 1nseA-3vv4A:
undetectable
1nseB-3vv4A:
undetectable		 1nseA-3vv4A:
19.91
1nseB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6L_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.14A 1p6lA-3vv4A:
undetectable
1p6lB-3vv4A:
undetectable		 1p6lA-3vv4A:
20.05
1p6lB-3vv4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6L_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.11A 1p6lA-3vv4A:
undetectable
1p6lB-3vv4A:
undetectable		 1p6lA-3vv4A:
20.05
1p6lB-3vv4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.14A 1p6mA-3vv4A:
undetectable
1p6mB-3vv4A:
undetectable		 1p6mA-3vv4A:
20.05
1p6mB-3vv4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.11A 1p6mA-3vv4A:
undetectable
1p6mB-3vv4A:
undetectable		 1p6mA-3vv4A:
20.05
1p6mB-3vv4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.15A 1p6nA-3vv4A:
undetectable
1p6nB-3vv4A:
1.7		 1p6nA-3vv4A:
20.05
1p6nB-3vv4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6N_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.14A 1p6nA-3vv4A:
undetectable
1p6nB-3vv4A:
1.7		 1p6nA-3vv4A:
20.05
1p6nB-3vv4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q2O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.11A 1q2oA-3vv4A:
undetectable
1q2oB-3vv4A:
1.9		 1q2oA-3vv4A:
20.05
1q2oB-3vv4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q2O_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.10A 1q2oA-3vv4A:
undetectable
1q2oB-3vv4A:
1.9		 1q2oA-3vv4A:
20.05
1q2oB-3vv4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS8_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.11A 1rs8A-3vv4A:
undetectable
1rs8B-3vv4A:
1.8		 1rs8A-3vv4A:
20.05
1rs8B-3vv4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS8_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.13A 1rs8A-3vv4A:
undetectable
1rs8B-3vv4A:
1.8		 1rs8A-3vv4A:
20.05
1rs8B-3vv4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS9_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.20A 1rs9A-3vv4A:
1.9
1rs9B-3vv4A:
undetectable		 1rs9A-3vv4A:
20.05
1rs9B-3vv4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS9_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.14A 1rs9A-3vv4A:
1.9
1rs9B-3vv4A:
undetectable		 1rs9A-3vv4A:
20.05
1rs9B-3vv4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.13A 1zzrA-3vv4A:
undetectable
1zzrB-3vv4A:
undetectable		 1zzrA-3vv4A:
19.33
1zzrB-3vv4A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.09A 1zzrA-3vv4A:
undetectable
1zzrB-3vv4A:
undetectable		 1zzrA-3vv4A:
19.33
1zzrB-3vv4A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZS_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.08A 1zzsA-3vv4A:
1.8
1zzsB-3vv4A:
undetectable		 1zzsA-3vv4A:
20.05
1zzsB-3vv4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZS_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.12A 1zzsA-3vv4A:
1.8
1zzsB-3vv4A:
undetectable		 1zzsA-3vv4A:
20.05
1zzsB-3vv4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.13A 1zzuA-3vv4A:
undetectable
1zzuB-3vv4A:
1.7		 1zzuA-3vv4A:
19.33
1zzuB-3vv4A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.13A 1zzuA-3vv4A:
undetectable
1zzuB-3vv4A:
1.7		 1zzuA-3vv4A:
19.33
1zzuB-3vv4A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX2_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.10A 2hx2A-3vv4A:
undetectable
2hx2B-3vv4A:
undetectable		 2hx2A-3vv4A:
20.05
2hx2B-3vv4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX2_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.13A 2hx2A-3vv4A:
undetectable
2hx2B-3vv4A:
undetectable		 2hx2A-3vv4A:
20.05
2hx2B-3vv4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.07A 2nseA-3vv4A:
undetectable
2nseB-3vv4A:
undetectable		 2nseA-3vv4A:
19.91
2nseB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.06A 3dqrA-3vv4A:
undetectable
3dqrB-3vv4A:
undetectable		 3dqrA-3vv4A:
19.24
3dqrB-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 0.99A 3dqrA-3vv4A:
undetectable
3dqrB-3vv4A:
undetectable		 3dqrA-3vv4A:
19.24
3dqrB-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.06A 3dqsA-3vv4A:
1.8
3dqsB-3vv4A:
undetectable		 3dqsA-3vv4A:
20.05
3dqsB-3vv4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.08A 3dqsA-3vv4A:
0.0
3dqsB-3vv4A:
0.0		 3dqsA-3vv4A:
20.05
3dqsB-3vv4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.08A 3dqtA-3vv4A:
undetectable
3dqtB-3vv4A:
1.8		 3dqtA-3vv4A:
20.05
3dqtB-3vv4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.09A 3dqtA-3vv4A:
undetectable
3dqtB-3vv4A:
undetectable		 3dqtA-3vv4A:
20.05
3dqtB-3vv4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWX_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.01A 3jwxA-3vv4A:
undetectable
3jwxB-3vv4A:
1.7		 3jwxA-3vv4A:
19.91
3jwxB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWX_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.03A 3jwxA-3vv4A:
undetectable
3jwxB-3vv4A:
1.7		 3jwxA-3vv4A:
19.91
3jwxB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.05A 3jwyA-3vv4A:
0.3
3jwyB-3vv4A:
1.8		 3jwyA-3vv4A:
19.91
3jwyB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.04A 3jwyA-3vv4A:
0.3
3jwyB-3vv4A:
1.8		 3jwyA-3vv4A:
19.91
3jwyB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.07A 3jwzA-3vv4A:
1.7
3jwzB-3vv4A:
undetectable		 3jwzA-3vv4A:
19.91
3jwzB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.05A 3jwzA-3vv4A:
1.7
3jwzB-3vv4A:
undetectable		 3jwzA-3vv4A:
19.91
3jwzB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.06A 3jx2A-3vv4A:
undetectable
3jx2B-3vv4A:
undetectable		 3jx2A-3vv4A:
19.24
3jx2B-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.05A 3jx2A-3vv4A:
undetectable
3jx2B-3vv4A:
undetectable		 3jx2A-3vv4A:
19.24
3jx2B-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.09A 3jx3A-3vv4A:
undetectable
3jx3B-3vv4A:
undetectable		 3jx3A-3vv4A:
19.24
3jx3B-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.08A 3jx3A-3vv4A:
undetectable
3jx3B-3vv4A:
undetectable		 3jx3A-3vv4A:
19.24
3jx3B-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.03A 3jx4A-3vv4A:
undetectable
3jx4B-3vv4A:
undetectable		 3jx4A-3vv4A:
19.24
3jx4B-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.06A 3jx5A-3vv4A:
undetectable
3jx5B-3vv4A:
0.4		 3jx5A-3vv4A:
19.24
3jx5B-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 0.99A 3jx5A-3vv4A:
undetectable
3jx5B-3vv4A:
undetectable		 3jx5A-3vv4A:
19.24
3jx5B-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 0.98A 3jx6A-3vv4A:
undetectable
3jx6B-3vv4A:
undetectable		 3jx6A-3vv4A:
19.24
3jx6B-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.10A 3jx6A-3vv4A:
undetectable
3jx6B-3vv4A:
undetectable		 3jx6A-3vv4A:
19.24
3jx6B-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Q_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.06A 3n5qA-3vv4A:
undetectable
3n5qB-3vv4A:
1.6		 3n5qA-3vv4A:
19.91
3n5qB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5R_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.09A 3n5rA-3vv4A:
undetectable
3n5rB-3vv4A:
undetectable		 3n5rA-3vv4A:
19.91
3n5rB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5R_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.08A 3n5rA-3vv4A:
undetectable
3n5rB-3vv4A:
undetectable		 3n5rA-3vv4A:
19.91
3n5rB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5S_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.04A 3n5sA-3vv4A:
1.7
3n5sB-3vv4A:
1.7		 3n5sA-3vv4A:
19.91
3n5sB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5S_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.05A 3n5sA-3vv4A:
1.7
3n5sB-3vv4A:
1.7		 3n5sA-3vv4A:
19.91
3n5sB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.06A 3n5tA-3vv4A:
undetectable
3n5tB-3vv4A:
undetectable		 3n5tA-3vv4A:
19.91
3n5tB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.06A 3n5tA-3vv4A:
undetectable
3n5tB-3vv4A:
undetectable		 3n5tA-3vv4A:
19.91
3n5tB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.07A 3n61A-3vv4A:
undetectable
3n61B-3vv4A:
0.4		 3n61A-3vv4A:
19.24
3n61B-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.07A 3n61A-3vv4A:
undetectable
3n61B-3vv4A:
undetectable		 3n61A-3vv4A:
19.24
3n61B-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6E_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.04A 3n6eA-3vv4A:
undetectable
3n6eB-3vv4A:
0.2		 3n6eA-3vv4A:
19.91
3n6eB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6E_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.07A 3n6eA-3vv4A:
undetectable
3n6eB-3vv4A:
0.2		 3n6eA-3vv4A:
19.91
3n6eB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6F_A_H4BA600_1
('NITRIC OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.05A 3n6fA-3vv4A:
undetectable
3n6fB-3vv4A:
1.8		 3n6fA-3vv4A:
19.91
3n6fB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6F_B_H4BB600_1
('NITRIC OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.04A 3n6fA-3vv4A:
undetectable
3n6fB-3vv4A:
1.8		 3n6fA-3vv4A:
19.91
3n6fB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6G_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.06A 3n6gA-3vv4A:
undetectable
3n6gB-3vv4A:
undetectable		 3n6gA-3vv4A:
19.91
3n6gB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6G_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.03A 3n6gA-3vv4A:
undetectable
3n6gB-3vv4A:
undetectable		 3n6gA-3vv4A:
19.91
3n6gB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLD_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.03A 3nldA-3vv4A:
0.0
3nldB-3vv4A:
0.0		 3nldA-3vv4A:
19.91
3nldB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.01A 3nleA-3vv4A:
1.7
3nleB-3vv4A:
1.7		 3nleA-3vv4A:
19.91
3nleB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLE_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.06A 3nleA-3vv4A:
1.7
3nleB-3vv4A:
1.7		 3nleA-3vv4A:
19.91
3nleB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLF_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.01A 3nlfA-3vv4A:
undetectable
3nlfB-3vv4A:
1.7		 3nlfA-3vv4A:
19.91
3nlfB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLG_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.05A 3nlgA-3vv4A:
undetectable
3nlgB-3vv4A:
1.8		 3nlgA-3vv4A:
19.91
3nlgB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLG_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.06A 3nlgA-3vv4A:
undetectable
3nlgB-3vv4A:
1.8		 3nlgA-3vv4A:
19.91
3nlgB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLH_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.05A 3nlhA-3vv4A:
undetectable
3nlhB-3vv4A:
1.7		 3nlhA-3vv4A:
19.91
3nlhB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLH_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.06A 3nlhA-3vv4A:
undetectable
3nlhB-3vv4A:
1.7		 3nlhA-3vv4A:
19.91
3nlhB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLI_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.03A 3nliA-3vv4A:
1.5
3nliB-3vv4A:
undetectable		 3nliA-3vv4A:
19.91
3nliB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLI_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.04A 3nliA-3vv4A:
1.5
3nliB-3vv4A:
undetectable		 3nliA-3vv4A:
19.91
3nliB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.01A 3nljA-3vv4A:
0.3
3nljB-3vv4A:
undetectable		 3nljA-3vv4A:
19.24
3nljB-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.00A 3nljA-3vv4A:
0.3
3nljB-3vv4A:
undetectable		 3nljA-3vv4A:
19.24
3nljB-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.07A 3nlpA-3vv4A:
undetectable
3nlpB-3vv4A:
undetectable		 3nlpA-3vv4A:
19.24
3nlpB-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.03A 3nlpA-3vv4A:
undetectable
3nlpB-3vv4A:
undetectable		 3nlpA-3vv4A:
19.24
3nlpB-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 8 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.09A 3nlqA-3vv4A:
undetectable
3nlqB-3vv4A:
undetectable		 3nlqA-3vv4A:
19.24
3nlqB-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.09A 3nlqA-3vv4A:
undetectable
3nlqB-3vv4A:
undetectable		 3nlqA-3vv4A:
19.24
3nlqB-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.12A 3nlrA-3vv4A:
undetectable
3nlrB-3vv4A:
undetectable		 3nlrA-3vv4A:
19.24
3nlrB-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 8 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.04A 3nlrA-3vv4A:
undetectable
3nlrB-3vv4A:
undetectable		 3nlrA-3vv4A:
19.24
3nlrB-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLU_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.04A 3nluA-3vv4A:
undetectable
3nluB-3vv4A:
1.7		 3nluA-3vv4A:
19.91
3nluB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NOS_A_H4BA511_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.12A 3nosA-3vv4A:
1.3
3nosB-3vv4A:
1.3		 3nosA-3vv4A:
18.37
3nosB-3vv4A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NOS_B_H4BB1011_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.08A 3nosA-3vv4A:
1.3
3nosB-3vv4A:
1.3		 3nosA-3vv4A:
18.37
3nosB-3vv4A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNH_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.04A 3pnhA-3vv4A:
1.7
3pnhB-3vv4A:
1.8		 3pnhA-3vv4A:
20.05
3pnhB-3vv4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNH_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.06A 3pnhA-3vv4A:
1.7
3pnhB-3vv4A:
1.8		 3pnhA-3vv4A:
20.05
3pnhB-3vv4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQO_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.00A 3rqoA-3vv4A:
0.0
3rqoB-3vv4A:
0.0		 3rqoA-3vv4A:
19.96
3rqoB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQO_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.09A 3rqoA-3vv4A:
undetectable
3rqoB-3vv4A:
undetectable		 3rqoA-3vv4A:
19.96
3rqoB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQP_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.04A 3rqpA-3vv4A:
undetectable
3rqpB-3vv4A:
1.7		 3rqpA-3vv4A:
19.96
3rqpB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C3A_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.04A 4c3aA-3vv4A:
undetectable
4c3aB-3vv4A:
undetectable		 4c3aA-3vv4A:
19.96
4c3aB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C3A_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.05A 4c3aA-3vv4A:
undetectable
4c3aB-3vv4A:
undetectable		 4c3aA-3vv4A:
19.96
4c3aB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAR_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.05A 4carA-3vv4A:
undetectable
4carB-3vv4A:
undetectable		 4carA-3vv4A:
19.96
4carB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAR_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.02A 4carA-3vv4A:
undetectable
4carB-3vv4A:
undetectable		 4carA-3vv4A:
19.96
4carB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CFT_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.11A 4cftA-3vv4A:
undetectable
4cftB-3vv4A:
0.2		 4cftA-3vv4A:
19.96
4cftB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CFT_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.09A 4cftA-3vv4A:
undetectable
4cftB-3vv4A:
0.2		 4cftA-3vv4A:
19.96
4cftB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.02A 4ctyA-3vv4A:
undetectable
4ctyB-3vv4A:
1.7		 4ctyA-3vv4A:
19.96
4ctyB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.04A 4ctyA-3vv4A:
undetectable
4ctyB-3vv4A:
1.7		 4ctyA-3vv4A:
19.96
4ctyB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.10A 4ctzA-3vv4A:
undetectable
4ctzB-3vv4A:
undetectable		 4ctzA-3vv4A:
19.96
4ctzB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.04A 4ctzA-3vv4A:
undetectable
4ctzB-3vv4A:
undetectable		 4ctzA-3vv4A:
19.96
4ctzB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU0_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.04A 4cu0A-3vv4A:
1.8
4cu0B-3vv4A:
1.4		 4cu0A-3vv4A:
19.96
4cu0B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU0_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.05A 4cu0A-3vv4A:
1.8
4cu0B-3vv4A:
1.4		 4cu0A-3vv4A:
19.96
4cu0B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU1_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.08A 4cu1A-3vv4A:
1.7
4cu1B-3vv4A:
undetectable		 4cu1A-3vv4A:
19.96
4cu1B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU1_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.11A 4cu1A-3vv4A:
1.7
4cu1B-3vv4A:
undetectable		 4cu1A-3vv4A:
19.96
4cu1B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWV_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.04A 4cwvA-3vv4A:
undetectable
4cwvB-3vv4A:
1.8		 4cwvA-3vv4A:
19.96
4cwvB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWV_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.10A 4cwvA-3vv4A:
undetectable
4cwvB-3vv4A:
1.8		 4cwvA-3vv4A:
19.96
4cwvB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWW_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.08A 4cwwA-3vv4A:
undetectable
4cwwB-3vv4A:
undetectable		 4cwwA-3vv4A:
19.96
4cwwB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWW_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.09A 4cwwA-3vv4A:
undetectable
4cwwB-3vv4A:
undetectable		 4cwwA-3vv4A:
19.96
4cwwB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWX_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.02A 4cwxA-3vv4A:
undetectable
4cwxB-3vv4A:
1.8		 4cwxA-3vv4A:
19.96
4cwxB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWX_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.06A 4cwxA-3vv4A:
undetectable
4cwxB-3vv4A:
1.8		 4cwxA-3vv4A:
19.96
4cwxB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.05A 4cwyA-3vv4A:
undetectable
4cwyB-3vv4A:
undetectable		 4cwyA-3vv4A:
19.96
4cwyB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.05A 4cwyA-3vv4A:
undetectable
4cwyB-3vv4A:
undetectable		 4cwyA-3vv4A:
19.96
4cwyB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.07A 4cwzA-3vv4A:
undetectable
4cwzB-3vv4A:
undetectable		 4cwzA-3vv4A:
19.96
4cwzB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.09A 4cwzA-3vv4A:
undetectable
4cwzB-3vv4A:
undetectable		 4cwzA-3vv4A:
19.96
4cwzB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX0_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.07A 4cx0A-3vv4A:
undetectable
4cx0B-3vv4A:
1.7		 4cx0A-3vv4A:
19.96
4cx0B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX0_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.10A 4cx0A-3vv4A:
undetectable
4cx0B-3vv4A:
1.7		 4cx0A-3vv4A:
19.96
4cx0B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.12A 4cx3A-3vv4A:
undetectable
4cx3B-3vv4A:
undetectable		 4cx3A-3vv4A:
19.24
4cx3B-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.13A 4cx3A-3vv4A:
0.2
4cx3B-3vv4A:
undetectable		 4cx3A-3vv4A:
19.24
4cx3B-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.14A 4cx4A-3vv4A:
0.2
4cx4B-3vv4A:
undetectable		 4cx4A-3vv4A:
19.24
4cx4B-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.13A 4cx4A-3vv4A:
0.2
4cx4B-3vv4A:
undetectable		 4cx4A-3vv4A:
19.24
4cx4B-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1O_A_H4BA1481_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.15A 4d1oA-3vv4A:
undetectable
4d1oB-3vv4A:
undetectable		 4d1oA-3vv4A:
18.33
4d1oB-3vv4A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1O_B_H4BB1481_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.12A 4d1oA-3vv4A:
undetectable
4d1oB-3vv4A:
undetectable		 4d1oA-3vv4A:
18.33
4d1oB-3vv4A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1P_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.07A 4d1pA-3vv4A:
undetectable
4d1pB-3vv4A:
1.9		 4d1pA-3vv4A:
18.33
4d1pB-3vv4A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.08A 4d33A-3vv4A:
undetectable
4d33B-3vv4A:
undetectable		 4d33A-3vv4A:
19.96
4d33B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.09A 4d33A-3vv4A:
undetectable
4d33B-3vv4A:
undetectable		 4d33A-3vv4A:
19.96
4d33B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D34_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.07A 4d34A-3vv4A:
undetectable
4d34B-3vv4A:
0.2		 4d34A-3vv4A:
19.96
4d34B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D34_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.05A 4d34A-3vv4A:
undetectable
4d34B-3vv4A:
0.2		 4d34A-3vv4A:
19.96
4d34B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D35_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.12A 4d35A-3vv4A:
undetectable
4d35B-3vv4A:
undetectable		 4d35A-3vv4A:
19.96
4d35B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D35_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.04A 4d35A-3vv4A:
undetectable
4d35B-3vv4A:
undetectable		 4d35A-3vv4A:
19.96
4d35B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D36_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.05A 4d36A-3vv4A:
1.4
4d36B-3vv4A:
1.4		 4d36A-3vv4A:
19.96
4d36B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D36_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.05A 4d36A-3vv4A:
1.4
4d36B-3vv4A:
1.4		 4d36A-3vv4A:
19.96
4d36B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D37_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.10A 4d37A-3vv4A:
undetectable
4d37B-3vv4A:
undetectable		 4d37A-3vv4A:
19.96
4d37B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D37_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.05A 4d37A-3vv4A:
undetectable
4d37B-3vv4A:
undetectable		 4d37A-3vv4A:
19.96
4d37B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D38_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.10A 4d38A-3vv4A:
0.4
4d38B-3vv4A:
undetectable		 4d38A-3vv4A:
19.96
4d38B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D38_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.05A 4d38A-3vv4A:
0.4
4d38B-3vv4A:
undetectable		 4d38A-3vv4A:
19.96
4d38B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.07A 4d39A-3vv4A:
1.4
4d39B-3vv4A:
undetectable		 4d39A-3vv4A:
19.96
4d39B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.09A 4d39A-3vv4A:
1.4
4d39B-3vv4A:
undetectable		 4d39A-3vv4A:
19.96
4d39B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3A_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.09A 4d3aA-3vv4A:
undetectable
4d3aB-3vv4A:
undetectable		 4d3aA-3vv4A:
19.96
4d3aB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3A_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.03A 4d3aA-3vv4A:
undetectable
4d3aB-3vv4A:
undetectable		 4d3aA-3vv4A:
19.96
4d3aB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMX_A_H4BA502_1
(SUBUNIT A)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.06A 4imxA-3vv4A:
undetectable
4imxB-3vv4A:
undetectable		 4imxA-3vv4A:
19.78
4imxB-3vv4A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMX_B_H4BB502_1
(SUBUNIT A)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.05A 4imxA-3vv4A:
undetectable
4imxB-3vv4A:
undetectable		 4imxA-3vv4A:
19.78
4imxB-3vv4A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSK_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 0.98A 4jskA-3vv4A:
undetectable
4jskB-3vv4A:
1.8		 4jskA-3vv4A:
19.96
4jskB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSL_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.07A 4jslA-3vv4A:
undetectable
4jslB-3vv4A:
1.7		 4jslA-3vv4A:
19.96
4jslB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSL_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.07A 4jslA-3vv4A:
undetectable
4jslB-3vv4A:
1.7		 4jslA-3vv4A:
19.96
4jslB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSM_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.08A 4jsmA-3vv4A:
undetectable
4jsmB-3vv4A:
undetectable		 4jsmA-3vv4A:
19.96
4jsmB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSM_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.12A 4jsmA-3vv4A:
1.2
4jsmB-3vv4A:
undetectable		 4jsmA-3vv4A:
19.96
4jsmB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5H_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.05A 4k5hA-3vv4A:
undetectable
4k5hB-3vv4A:
1.7		 4k5hA-3vv4A:
19.96
4k5hB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5H_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.09A 4k5hA-3vv4A:
undetectable
4k5hB-3vv4A:
1.7		 4k5hA-3vv4A:
19.96
4k5hB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5I_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.06A 4k5iA-3vv4A:
undetectable
4k5iB-3vv4A:
undetectable		 4k5iA-3vv4A:
19.96
4k5iB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5I_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.08A 4k5iA-3vv4A:
undetectable
4k5iB-3vv4A:
undetectable		 4k5iA-3vv4A:
19.96
4k5iB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.10A 4k5jA-3vv4A:
0.2
4k5jB-3vv4A:
undetectable		 4k5jA-3vv4A:
19.96
4k5jB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.07A 4k5jA-3vv4A:
undetectable
4k5jB-3vv4A:
undetectable		 4k5jA-3vv4A:
19.96
4k5jB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5K_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.05A 4k5kA-3vv4A:
1.7
4k5kB-3vv4A:
undetectable		 4k5kA-3vv4A:
19.96
4k5kB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5K_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.09A 4k5kA-3vv4A:
1.7
4k5kB-3vv4A:
undetectable		 4k5kA-3vv4A:
19.96
4k5kB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCP_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.00A 4kcpA-3vv4A:
undetectable
4kcpB-3vv4A:
1.7		 4kcpA-3vv4A:
19.96
4kcpB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCP_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.05A 4kcpA-3vv4A:
undetectable
4kcpB-3vv4A:
1.7		 4kcpA-3vv4A:
19.96
4kcpB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCQ_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.06A 4kcqA-3vv4A:
1.8
4kcqB-3vv4A:
undetectable		 4kcqA-3vv4A:
19.96
4kcqB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCQ_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.09A 4kcqA-3vv4A:
1.8
4kcqB-3vv4A:
undetectable		 4kcqA-3vv4A:
19.96
4kcqB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCR_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.04A 4kcrA-3vv4A:
undetectable
4kcrB-3vv4A:
undetectable		 4kcrA-3vv4A:
19.96
4kcrB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCR_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.07A 4kcrA-3vv4A:
undetectable
4kcrB-3vv4A:
undetectable		 4kcrA-3vv4A:
19.96
4kcrB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCS_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.03A 4kcsA-3vv4A:
1.4
4kcsB-3vv4A:
undetectable		 4kcsA-3vv4A:
19.96
4kcsB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCS_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.04A 4kcsA-3vv4A:
1.4
4kcsB-3vv4A:
undetectable		 4kcsA-3vv4A:
19.96
4kcsB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUW_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.08A 4luwA-3vv4A:
undetectable
4luwB-3vv4A:
undetectable		 4luwA-3vv4A:
20.00
4luwB-3vv4A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUW_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.06A 4luwA-3vv4A:
undetectable
4luwB-3vv4A:
undetectable		 4luwA-3vv4A:
20.00
4luwB-3vv4A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_0
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		5 / 12 ALA A  82
PHE A 141
ALA A 124
VAL A  32
GLN A  81
 None
None
None
None
PVG  A 201 (-3.4A)
 1.39A 4ryaA-3vv4A:
undetectable		 4ryaA-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.08A 4uh7A-3vv4A:
undetectable
4uh7B-3vv4A:
undetectable		 4uh7A-3vv4A:
19.96
4uh7B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.07A 4uh7A-3vv4A:
undetectable
4uh7B-3vv4A:
undetectable		 4uh7A-3vv4A:
19.96
4uh7B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH8_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.09A 4uh8A-3vv4A:
undetectable
4uh8B-3vv4A:
undetectable		 4uh8A-3vv4A:
19.96
4uh8B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH8_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.06A 4uh8A-3vv4A:
undetectable
4uh8B-3vv4A:
undetectable		 4uh8A-3vv4A:
19.96
4uh8B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH9_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.06A 4uh9A-3vv4A:
1.6
4uh9B-3vv4A:
undetectable		 4uh9A-3vv4A:
19.96
4uh9B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH9_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.06A 4uh9A-3vv4A:
1.6
4uh9B-3vv4A:
undetectable		 4uh9A-3vv4A:
19.96
4uh9B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHA_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.06A 4uhaA-3vv4A:
undetectable
4uhaB-3vv4A:
undetectable		 4uhaA-3vv4A:
19.96
4uhaB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHA_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.07A 4uhaA-3vv4A:
undetectable
4uhaB-3vv4A:
undetectable		 4uhaA-3vv4A:
19.96
4uhaB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPQ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.08A 4upqA-3vv4A:
undetectable
4upqB-3vv4A:
undetectable		 4upqA-3vv4A:
19.96
4upqB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPQ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.06A 4upqA-3vv4A:
undetectable
4upqB-3vv4A:
undetectable		 4upqA-3vv4A:
19.96
4upqB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPR_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.05A 4uprA-3vv4A:
undetectable
4uprB-3vv4A:
1.7		 4uprA-3vv4A:
19.96
4uprB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPR_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.06A 4uprA-3vv4A:
undetectable
4uprB-3vv4A:
1.7		 4uprA-3vv4A:
19.96
4uprB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPS_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.07A 4upsA-3vv4A:
undetectable
4upsB-3vv4A:
1.8		 4upsA-3vv4A:
19.96
4upsB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPS_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.08A 4upsA-3vv4A:
undetectable
4upsB-3vv4A:
1.8		 4upsA-3vv4A:
19.96
4upsB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPT_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.03A 4uptA-3vv4A:
undetectable
4uptB-3vv4A:
undetectable		 4uptA-3vv4A:
19.96
4uptB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPT_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.05A 4uptA-3vv4A:
undetectable
4uptB-3vv4A:
undetectable		 4uptA-3vv4A:
19.96
4uptB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADJ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.10A 5adjA-3vv4A:
undetectable
5adjB-3vv4A:
undetectable		 5adjA-3vv4A:
19.96
5adjB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADJ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.08A 5adjA-3vv4A:
undetectable
5adjB-3vv4A:
undetectable		 5adjA-3vv4A:
19.96
5adjB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADK_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.08A 5adkA-3vv4A:
undetectable
5adkB-3vv4A:
undetectable		 5adkA-3vv4A:
19.96
5adkB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADK_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.09A 5adkA-3vv4A:
undetectable
5adkB-3vv4A:
undetectable		 5adkA-3vv4A:
19.96
5adkB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.08A 5adlA-3vv4A:
undetectable
5adlB-3vv4A:
1.3		 5adlA-3vv4A:
19.96
5adlB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.03A 5adlA-3vv4A:
undetectable
5adlB-3vv4A:
undetectable		 5adlA-3vv4A:
19.96
5adlB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADM_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.10A 5admA-3vv4A:
undetectable
5admB-3vv4A:
1.7		 5admA-3vv4A:
19.96
5admB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADM_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.06A 5admA-3vv4A:
undetectable
5admB-3vv4A:
1.7		 5admA-3vv4A:
19.96
5admB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADN_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.09A 5adnA-3vv4A:
undetectable
5adnB-3vv4A:
undetectable		 5adnA-3vv4A:
19.96
5adnB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADN_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.10A 5adnA-3vv4A:
undetectable
5adnB-3vv4A:
undetectable		 5adnA-3vv4A:
19.96
5adnB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ2_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.10A 5fj2A-3vv4A:
undetectable
5fj2B-3vv4A:
undetectable		 5fj2A-3vv4A:
19.96
5fj2B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ2_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.06A 5fj2A-3vv4A:
undetectable
5fj2B-3vv4A:
undetectable		 5fj2A-3vv4A:
19.96
5fj2B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.09A 5fj3A-3vv4A:
undetectable
5fj3B-3vv4A:
1.7		 5fj3A-3vv4A:
19.96
5fj3B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.07A 5fj3A-3vv4A:
undetectable
5fj3B-3vv4A:
undetectable		 5fj3A-3vv4A:
19.96
5fj3B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.09A 5fvyA-3vv4A:
undetectable
5fvyB-3vv4A:
undetectable		 5fvyA-3vv4A:
19.96
5fvyB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.06A 5fvyA-3vv4A:
undetectable
5fvyB-3vv4A:
undetectable		 5fvyA-3vv4A:
19.96
5fvyB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVZ_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.06A 5fvzA-3vv4A:
undetectable
5fvzB-3vv4A:
undetectable		 5fvzA-3vv4A:
19.96
5fvzB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVZ_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.04A 5fvzA-3vv4A:
undetectable
5fvzB-3vv4A:
undetectable		 5fvzA-3vv4A:
19.96
5fvzB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.01A 5g0pA-3vv4A:
undetectable
5g0pB-3vv4A:
undetectable		 5g0pA-3vv4A:
19.24
5g0pB-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.04A 5g0pA-3vv4A:
undetectable
5g0pB-3vv4A:
undetectable		 5g0pA-3vv4A:
19.24
5g0pB-3vv4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.00A 5uo8A-3vv4A:
undetectable
5uo8B-3vv4A:
undetectable		 5uo8A-3vv4A:
18.33
5uo8B-3vv4A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.03A 5uo8C-3vv4A:
undetectable
5uo8D-3vv4A:
undetectable		 5uo8C-3vv4A:
18.33
5uo8D-3vv4A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.15A 5uo9A-3vv4A:
undetectable
5uo9B-3vv4A:
undetectable		 5uo9A-3vv4A:
18.33
5uo9B-3vv4A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.09A 5uo9A-3vv4A:
undetectable
5uo9B-3vv4A:
undetectable		 5uo9A-3vv4A:
18.33
5uo9B-3vv4A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.08A 5uo9C-3vv4A:
undetectable
5uo9D-3vv4A:
undetectable		 5uo9C-3vv4A:
18.33
5uo9D-3vv4A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOD_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.10A 5uodA-3vv4A:
undetectable
5uodB-3vv4A:
undetectable		 5uodA-3vv4A:
19.96
5uodB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOD_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.08A 5uodA-3vv4A:
undetectable
5uodB-3vv4A:
undetectable		 5uodA-3vv4A:
19.96
5uodB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV6_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.03A 5vv6A-3vv4A:
undetectable
5vv6B-3vv4A:
undetectable		 5vv6A-3vv4A:
19.96
5vv6B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV6_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.02A 5vv6A-3vv4A:
undetectable
5vv6B-3vv4A:
undetectable		 5vv6A-3vv4A:
19.96
5vv6B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.08A 5vv7A-3vv4A:
undetectable
5vv7B-3vv4A:
1.7		 5vv7A-3vv4A:
19.96
5vv7B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.08A 5vv7A-3vv4A:
undetectable
5vv7B-3vv4A:
undetectable		 5vv7A-3vv4A:
19.96
5vv7B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV8_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.05A 5vv8A-3vv4A:
undetectable
5vv8B-3vv4A:
undetectable		 5vv8A-3vv4A:
19.96
5vv8B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV8_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.05A 5vv8A-3vv4A:
undetectable
5vv8B-3vv4A:
undetectable		 5vv8A-3vv4A:
19.96
5vv8B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV9_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.03A 5vv9A-3vv4A:
undetectable
5vv9B-3vv4A:
undetectable		 5vv9A-3vv4A:
19.96
5vv9B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV9_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.06A 5vv9A-3vv4A:
0.0
5vv9B-3vv4A:
0.0		 5vv9A-3vv4A:
19.96
5vv9B-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVA_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.05A 5vvaA-3vv4A:
undetectable
5vvaB-3vv4A:
undetectable		 5vvaA-3vv4A:
19.96
5vvaB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVA_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.06A 5vvaA-3vv4A:
undetectable
5vvaB-3vv4A:
undetectable		 5vvaA-3vv4A:
19.96
5vvaB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVB_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.01A 5vvbC-3vv4A:
undetectable
5vvbD-3vv4A:
undetectable		 5vvbC-3vv4A:
18.33
5vvbD-3vv4A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.05A 5vvcA-3vv4A:
undetectable
5vvcB-3vv4A:
undetectable		 5vvcA-3vv4A:
18.33
5vvcB-3vv4A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.04A 5vvcC-3vv4A:
undetectable
5vvcD-3vv4A:
undetectable		 5vvcC-3vv4A:
18.33
5vvcD-3vv4A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.07A 5vvcC-3vv4A:
undetectable
5vvcD-3vv4A:
undetectable		 5vvcC-3vv4A:
18.33
5vvcD-3vv4A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVD_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.02A 5vvdA-3vv4A:
undetectable
5vvdB-3vv4A:
undetectable		 5vvdA-3vv4A:
18.33
5vvdB-3vv4A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVD_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.04A 5vvdC-3vv4A:
0.1
5vvdD-3vv4A:
undetectable		 5vvdC-3vv4A:
18.33
5vvdD-3vv4A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVG_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.01A 5vvgA-3vv4A:
1.3
5vvgB-3vv4A:
undetectable		 5vvgA-3vv4A:
19.96
5vvgB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVG_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.05A 5vvgA-3vv4A:
1.3
5vvgB-3vv4A:
undetectable		 5vvgA-3vv4A:
19.96
5vvgB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.01A 5vvnA-3vv4A:
undetectable
5vvnB-3vv4A:
undetectable		 5vvnA-3vv4A:
19.96
5vvnB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.05A 5vvnA-3vv4A:
undetectable
5vvnB-3vv4A:
undetectable		 5vvnA-3vv4A:
19.96
5vvnB-3vv4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.07A 6av6A-3vv4A:
undetectable
6av6B-3vv4A:
undetectable		 6av6A-3vv4A:
15.14
6av6B-3vv4A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB503_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.05A 6av6A-3vv4A:
undetectable
6av6B-3vv4A:
undetectable		 6av6A-3vv4A:
15.14
6av6B-3vv4A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.07A 6av6C-3vv4A:
undetectable
6av6D-3vv4A:
undetectable		 6av6C-3vv4A:
15.14
6av6D-3vv4A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.03A 6av6C-3vv4A:
undetectable
6av6D-3vv4A:
undetectable		 6av6C-3vv4A:
15.14
6av6D-3vv4A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.10A 6av7A-3vv4A:
undetectable
6av7B-3vv4A:
undetectable		 6av7A-3vv4A:
15.14
6av7B-3vv4A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.04A 6av7A-3vv4A:
undetectable
6av7B-3vv4A:
undetectable		 6av7A-3vv4A:
15.14
6av7B-3vv4A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.11A 6av7C-3vv4A:
undetectable
6av7D-3vv4A:
undetectable		 6av7C-3vv4A:
15.14
6av7D-3vv4A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.08A 6av7C-3vv4A:
undetectable
6av7D-3vv4A:
undetectable		 6av7C-3vv4A:
15.14
6av7D-3vv4A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_A_H4BA502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.10A 6cieA-3vv4A:
undetectable
6cieB-3vv4A:
undetectable		 6cieA-3vv4A:
15.14
6cieB-3vv4A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_B_H4BB502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 7 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.02A 6cieA-3vv4A:
undetectable
6cieB-3vv4A:
undetectable		 6cieA-3vv4A:
15.14
6cieB-3vv4A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_C_H4BC502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.10A 6cieC-3vv4A:
undetectable
6cieD-3vv4A:
undetectable		 6cieC-3vv4A:
15.14
6cieD-3vv4A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_D_H4BD502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.06A 6cieC-3vv4A:
0.0
6cieD-3vv4A:
0.0		 6cieC-3vv4A:
15.14
6cieD-3vv4A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
8NSE_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.17A 8nseA-3vv4A:
undetectable
8nseB-3vv4A:
undetectable		 8nseA-3vv4A:
19.91
8nseB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
8NSE_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.14A 8nseA-3vv4A:
undetectable
8nseB-3vv4A:
undetectable		 8nseA-3vv4A:
19.91
8nseB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
9NSE_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 VAL A  72
TRP A  71
PHE A  67
GLU A  73
 None
PVG  A 201 (-3.6A)
None
None
 1.09A 9nseA-3vv4A:
undetectable
9nseB-3vv4A:
undetectable		 9nseA-3vv4A:
19.91
9nseB-3vv4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
9NSE_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3vv4 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
(Thermosynechococ
cus
elongatus) 		4 / 6 PHE A  67
GLU A  73
VAL A  72
TRP A  71
 None
None
None
PVG  A 201 (-3.6A)
 1.11A 9nseA-3vv4A:
undetectable
9nseB-3vv4A:
undetectable		 9nseA-3vv4A:
19.91
9nseB-3vv4A:
19.91