SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'PRP'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3gbr ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A 117
SER A 269
ALA A 270
THR A  92
ILE A  96
 PRP  A 401 (-3.2A)
None
None
PRP  A 401 (-4.2A)
None
 0.98A 1gtnL-3gbrA:
undetectable
1gtnV-3gbrA:
undetectable		 1gtnL-3gbrA:
14.29
1gtnV-3gbrA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_1
(POL POLYPROTEIN)		 1d6n PROTEIN
(HYPOXANTHINE-GUANIN
E
PHOSPHORIBOSYLTRANSF
ERASE)
(Homo
sapiens) 		5 / 8 ALA A  68
ILE A 116
GLY A 117
GLY A 118
ILE A  99
 PRP  A 312 (-3.2A)
None
None
None
None
 1.22A 1sguA-1d6nA:
undetectable		 1sguA-1d6nA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3gbr ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Sulfolobus
solfataricus) 		5 / 12 THR A  92
ILE A  96
GLY A 117
SER A 269
ALA A 270
 PRP  A 401 (-4.2A)
None
PRP  A 401 (-3.2A)
None
None
 1.01A 1utdL-3gbrA:
undetectable
1utdM-3gbrA:
undetectable		 1utdL-3gbrA:
14.29
1utdM-3gbrA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3gbr ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Sulfolobus
solfataricus) 		5 / 12 THR A  92
ILE A  96
GLY A 117
SER A 269
ALA A 270
 PRP  A 401 (-4.2A)
None
PRP  A 401 (-3.2A)
None
None
 0.99A 1utdO-3gbrA:
undetectable
1utdP-3gbrA:
undetectable		 1utdO-3gbrA:
14.29
1utdP-3gbrA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3gbr ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Sulfolobus
solfataricus) 		5 / 11 THR A  92
ILE A  96
GLY A 117
SER A 269
ALA A 270
 PRP  A 401 (-4.2A)
None
PRP  A 401 (-3.2A)
None
None
 1.01A 1utdP-3gbrA:
undetectable
1utdQ-3gbrA:
undetectable		 1utdP-3gbrA:
14.29
1utdQ-3gbrA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4z1o PHOSPHORIBOSYLTRANSF
ERASE
(Sulfolobus
solfataricus) 		5 / 12 LEU A  90
LEU A  47
SER A 128
ALA A 121
ALA A  96
 None
None
None
None
PRP  A 201 ( 4.6A)
 0.96A 2br4C-4z1oA:
3.9		 2br4C-4z1oA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)		 3gbr ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Sulfolobus
solfataricus) 		4 / 7 ASP A 268
SER A 265
SER A 116
ASN A  89
 None
None
None
PRP  A 401 (-4.1A)
 0.88A 2cmlA-3gbrA:
undetectable		 2cmlA-3gbrA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)		 3gbr ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Sulfolobus
solfataricus) 		4 / 8 ASP A 268
SER A 265
SER A 116
ASN A  89
 None
None
None
PRP  A 401 (-4.1A)
 0.89A 2cmlC-3gbrA:
undetectable		 2cmlC-3gbrA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1d6n PROTEIN
(HYPOXANTHINE-GUANIN
E
PHOSPHORIBOSYLTRANSF
ERASE)
(Homo
sapiens) 		4 / 6 HIS A  38
ASP A 134
TYR A  71
HIS A 203
 None
PRP  A 312 ( 2.9A)
None
None
 1.50A 2einA-1d6nA:
undetectable
2einC-1d6nA:
undetectable		 2einA-1d6nA:
16.94
2einC-1d6nA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1103_0
(FERROCHELATASE)		 5hkf OROTATE
PHOSPHORIBOSYLTRANSF
ERASE
(Mycobacterium
tuberculosis) 		4 / 8 ARG A  38
SER A 109
VAL A 119
GLY A  68
 PRP  A 201 (-2.4A)
None
None
None
 1.11A 2qd5B-5hkfA:
undetectable		 2qd5B-5hkfA:
20.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RGL_A_GLYA301_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 4rv4 OROTATE
PHOSPHORIBOSYLTRANSF
ERASE
(Bacillus
anthracis) 		5 / 8 ALA A  74
GLY A  75
THR A  71
ARG A  38
GLU A 120
 PRP  A 301 (-3.3A)
None
PRP  A 301 ( 4.7A)
PRP  A 301 (-3.7A)
PRP  A 301 (-2.9A)
 1.21A 3rglA-4rv4A:
undetectable		 3rglA-4rv4A:
30.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 4rv4 OROTATE
PHOSPHORIBOSYLTRANSF
ERASE
(Bacillus
anthracis) 		5 / 12 ALA A  74
HIS A  78
GLY A  70
LYS A 105
ALA A 135
 PRP  A 301 (-3.3A)
None
None
None
None
 1.17A 3tm4A-4rv4A:
undetectable		 3tm4A-4rv4A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 4rv4 OROTATE
PHOSPHORIBOSYLTRANSF
ERASE
(Bacillus
anthracis) 		5 / 12 ALA A  74
HIS A  78
GLY A  70
LYS A 105
ALA A 135
 PRP  A 301 (-3.3A)
None
None
None
None
 1.12A 3tm4B-4rv4A:
undetectable		 3tm4B-4rv4A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4z1o PHOSPHORIBOSYLTRANSF
ERASE
(Sulfolobus
solfataricus) 		3 / 3 ARG A  65
GLU A 100
THR A 101
 PRP  A 201 (-2.8A)
None
PRP  A 201 (-3.5A)
 0.62A 3v4tA-4z1oA:
undetectable		 3v4tA-4z1oA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1d6n PROTEIN
(HYPOXANTHINE-GUANIN
E
PHOSPHORIBOSYLTRANSF
ERASE)
(Homo
sapiens) 		5 / 12 ASP A 134
GLY A  70
GLY A  69
ILE A 135
GLU A 196
 PRP  A 312 ( 2.9A)
PRP  A 312 (-3.1A)
PRP  A 312 (-4.3A)
PPO  A 300 ( 4.5A)
None
 1.00A 4jksA-1d6nA:
undetectable		 4jksA-1d6nA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1d6n PROTEIN
(HYPOXANTHINE-GUANIN
E
PHOSPHORIBOSYLTRANSF
ERASE)
(Homo
sapiens) 		5 / 12 ASP A 134
GLY A  70
GLY A  69
ILE A 135
GLU A 196
 PRP  A 312 ( 2.9A)
PRP  A 312 (-3.1A)
PRP  A 312 (-4.3A)
PPO  A 300 ( 4.5A)
None
 1.00A 4jksB-1d6nA:
undetectable		 4jksB-1d6nA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1d6n PROTEIN
(HYPOXANTHINE-GUANIN
E
PHOSPHORIBOSYLTRANSF
ERASE)
(Homo
sapiens) 		5 / 12 ASP A 134
GLY A  70
GLY A  69
ILE A 135
GLU A 196
 PRP  A 312 ( 2.9A)
PRP  A 312 (-3.1A)
PRP  A 312 (-4.3A)
PPO  A 300 ( 4.5A)
None
 1.00A 4jkuA-1d6nA:
undetectable		 4jkuA-1d6nA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 1d6n PROTEIN
(HYPOXANTHINE-GUANIN
E
PHOSPHORIBOSYLTRANSF
ERASE)
(Homo
sapiens) 		5 / 12 ASP A 134
GLY A  70
GLY A  69
ILE A 135
GLU A 196
 PRP  A 312 ( 2.9A)
PRP  A 312 (-3.1A)
PRP  A 312 (-4.3A)
PPO  A 300 ( 4.5A)
None
 0.99A 4k8cA-1d6nA:
undetectable		 4k8cA-1d6nA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 1d6n PROTEIN
(HYPOXANTHINE-GUANIN
E
PHOSPHORIBOSYLTRANSF
ERASE)
(Homo
sapiens) 		5 / 12 ASP A 134
GLY A  70
GLY A  69
ILE A 135
GLU A 196
 PRP  A 312 ( 2.9A)
PRP  A 312 (-3.1A)
PRP  A 312 (-4.3A)
PPO  A 300 ( 4.5A)
None
 0.98A 4k8cB-1d6nA:
undetectable		 4k8cB-1d6nA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 1d6n PROTEIN
(HYPOXANTHINE-GUANIN
E
PHOSPHORIBOSYLTRANSF
ERASE)
(Homo
sapiens) 		5 / 12 ASP A 134
GLY A  70
GLY A  69
ILE A 135
GLU A 196
 PRP  A 312 ( 2.9A)
PRP  A 312 (-3.1A)
PRP  A 312 (-4.3A)
PPO  A 300 ( 4.5A)
None
 1.00A 4k8kA-1d6nA:
undetectable		 4k8kA-1d6nA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 1d6n PROTEIN
(HYPOXANTHINE-GUANIN
E
PHOSPHORIBOSYLTRANSF
ERASE)
(Homo
sapiens) 		5 / 12 ASP A 134
GLY A  70
GLY A  69
ILE A 135
GLU A 196
 PRP  A 312 ( 2.9A)
PRP  A 312 (-3.1A)
PRP  A 312 (-4.3A)
PPO  A 300 ( 4.5A)
None
 1.01A 4k8kB-1d6nA:
undetectable		 4k8kB-1d6nA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1d6n PROTEIN
(HYPOXANTHINE-GUANIN
E
PHOSPHORIBOSYLTRANSF
ERASE)
(Homo
sapiens) 		5 / 12 ASP A 134
GLY A  70
GLY A  69
ILE A 135
GLU A 196
 PRP  A 312 ( 2.9A)
PRP  A 312 (-3.1A)
PRP  A 312 (-4.3A)
PPO  A 300 ( 4.5A)
None
 1.00A 4kahA-1d6nA:
undetectable		 4kahA-1d6nA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1d6n PROTEIN
(HYPOXANTHINE-GUANIN
E
PHOSPHORIBOSYLTRANSF
ERASE)
(Homo
sapiens) 		5 / 12 ASP A 134
GLY A  70
GLY A  69
ILE A 135
GLU A 196
 PRP  A 312 ( 2.9A)
PRP  A 312 (-3.1A)
PRP  A 312 (-4.3A)
PPO  A 300 ( 4.5A)
None
 0.98A 4kahB-1d6nA:
undetectable		 4kahB-1d6nA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1d6n PROTEIN
(HYPOXANTHINE-GUANIN
E
PHOSPHORIBOSYLTRANSF
ERASE)
(Homo
sapiens) 		5 / 12 ASP A 134
GLY A  70
GLY A  69
ILE A 135
GLU A 196
 PRP  A 312 ( 2.9A)
PRP  A 312 (-3.1A)
PRP  A 312 (-4.3A)
PPO  A 300 ( 4.5A)
None
 0.99A 4kalA-1d6nA:
undetectable		 4kalA-1d6nA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1d6n PROTEIN
(HYPOXANTHINE-GUANIN
E
PHOSPHORIBOSYLTRANSF
ERASE)
(Homo
sapiens) 		5 / 12 ASP A 134
GLY A  70
GLY A  69
ILE A 135
GLU A 196
 PRP  A 312 ( 2.9A)
PRP  A 312 (-3.1A)
PRP  A 312 (-4.3A)
PPO  A 300 ( 4.5A)
None
 0.98A 4kalB-1d6nA:
undetectable		 4kalB-1d6nA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1d6n PROTEIN
(HYPOXANTHINE-GUANIN
E
PHOSPHORIBOSYLTRANSF
ERASE)
(Homo
sapiens) 		5 / 12 ASP A 134
GLY A  70
GLY A  69
ILE A 135
GLU A 196
 PRP  A 312 ( 2.9A)
PRP  A 312 (-3.1A)
PRP  A 312 (-4.3A)
PPO  A 300 ( 4.5A)
None
 1.01A 4kanA-1d6nA:
undetectable		 4kanA-1d6nA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1d6n PROTEIN
(HYPOXANTHINE-GUANIN
E
PHOSPHORIBOSYLTRANSF
ERASE)
(Homo
sapiens) 		5 / 12 ASP A 134
GLY A  70
GLY A  69
ILE A 135
GLU A 196
 PRP  A 312 ( 2.9A)
PRP  A 312 (-3.1A)
PRP  A 312 (-4.3A)
PPO  A 300 ( 4.5A)
None
 1.00A 4kanB-1d6nA:
undetectable		 4kanB-1d6nA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1d6n PROTEIN
(HYPOXANTHINE-GUANIN
E
PHOSPHORIBOSYLTRANSF
ERASE)
(Homo
sapiens) 		5 / 12 ASP A 134
GLY A  70
GLY A  69
ILE A 135
GLU A 196
 PRP  A 312 ( 2.9A)
PRP  A 312 (-3.1A)
PRP  A 312 (-4.3A)
PPO  A 300 ( 4.5A)
None
 0.98A 4kbeA-1d6nA:
undetectable		 4kbeA-1d6nA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1d6n PROTEIN
(HYPOXANTHINE-GUANIN
E
PHOSPHORIBOSYLTRANSF
ERASE)
(Homo
sapiens) 		5 / 12 ASP A 134
GLY A  70
GLY A  69
ILE A 135
GLU A 196
 PRP  A 312 ( 2.9A)
PRP  A 312 (-3.1A)
PRP  A 312 (-4.3A)
PPO  A 300 ( 4.5A)
None
 0.99A 4kbeB-1d6nA:
undetectable		 4kbeB-1d6nA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1d6n PROTEIN
(HYPOXANTHINE-GUANIN
E
PHOSPHORIBOSYLTRANSF
ERASE)
(Homo
sapiens) 		5 / 12 ASP A 134
GLY A  70
GLY A  69
ILE A 135
GLU A 196
 PRP  A 312 ( 2.9A)
PRP  A 312 (-3.1A)
PRP  A 312 (-4.3A)
PPO  A 300 ( 4.5A)
None
 0.99A 4lbgA-1d6nA:
undetectable		 4lbgA-1d6nA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1d6n PROTEIN
(HYPOXANTHINE-GUANIN
E
PHOSPHORIBOSYLTRANSF
ERASE)
(Homo
sapiens) 		5 / 12 ASP A 134
GLY A  70
GLY A  69
ILE A 135
GLU A 196
 PRP  A 312 ( 2.9A)
PRP  A 312 (-3.1A)
PRP  A 312 (-4.3A)
PPO  A 300 ( 4.5A)
None
 1.00A 4lbgB-1d6nA:
undetectable		 4lbgB-1d6nA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1d6n PROTEIN
(HYPOXANTHINE-GUANIN
E
PHOSPHORIBOSYLTRANSF
ERASE)
(Homo
sapiens) 		5 / 12 ASP A 134
GLY A  70
GLY A  69
ILE A 135
GLU A 196
 PRP  A 312 ( 2.9A)
PRP  A 312 (-3.1A)
PRP  A 312 (-4.3A)
PPO  A 300 ( 4.5A)
None
 0.99A 4lcaA-1d6nA:
undetectable		 4lcaA-1d6nA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1d6n PROTEIN
(HYPOXANTHINE-GUANIN
E
PHOSPHORIBOSYLTRANSF
ERASE)
(Homo
sapiens) 		5 / 12 ASP A 134
GLY A  70
GLY A  69
ILE A 135
GLU A 196
 PRP  A 312 ( 2.9A)
PRP  A 312 (-3.1A)
PRP  A 312 (-4.3A)
PPO  A 300 ( 4.5A)
None
 0.98A 4lcaB-1d6nA:
undetectable		 4lcaB-1d6nA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_1
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 1d6n PROTEIN
(HYPOXANTHINE-GUANIN
E
PHOSPHORIBOSYLTRANSF
ERASE)
(Homo
sapiens) 		4 / 4 ASP A 193
GLY A  70
ASP A 134
ASP A 137
 None
PRP  A 312 (-3.1A)
PRP  A 312 ( 2.9A)
PPO  A 300 ( 3.9A)
 1.13A 5e72A-1d6nA:
undetectable		 5e72A-1d6nA:
23.15