SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'PRO'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	13GS_A_SASA211_1 (GLUTATHIONE S-TRANSFERASE)	5lmx	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA49 (Saccharomyces cerevisiae)	5 / 10	TYR M  76 PRO M  94 VAL M  95 VAL M  21 GLY M  24	TYR  M  76 ( 1.3A) PRO  M  94 ( 1.1A) VAL  M  95 ( 0.6A) VAL  M  21 ( 0.5A) GLY  M  24 ( 0.0A)	1.37A	13gsA-5lmxM: undetectable	13gsA-5lmxM: 20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A7Y_B_DVAB2_0 (ACTINOMYCIN D)	5w0a	GLUCANASE (Trichoderma harzianum)	3 / 3	THR A   5 PRO A   8 THR A   7	THR  A   5 ( 0.8A) PRO  A   8 ( 1.1A) THR  A   7 ( 0.8A)	0.83A	1a7yB-5w0aA: undetectable	1a7yB-5w0aA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DRF_A_FOLA187_0 (DIHYDROFOLATE REDUCTASE)	1ng0	COAT PROTEIN (Cocksfoot mottle virus)	5 / 12	ALA A  94 SER A 239 ILE A 241 PRO A 110 LEU A 243	ALA  A  94 ( 0.0A) SER  A 239 ( 0.0A) ILE  A 241 ( 0.7A) PRO  A 110 ( 1.1A) LEU  A 243 ( 0.6A)	0.99A	1drfA-1ng0A: undetectable	1drfA-1ng0A: 23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSC_C_DVAC2_0 (ACTINOMYCIN D)	3gle	PILIN (Streptococcus pyogenes)	3 / 3	THR A  84 PRO A  48 THR A  50	THR  A  84 ( 0.8A) PRO  A  48 ( 1.1A) THR  A  50 ( 0.8A)	0.86A	1dscC-3gleA: undetectable	1dscC-3gleA: 9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSC_C_DVAC2_0 (ACTINOMYCIN D)	5w0a	GLUCANASE (Trichoderma harzianum)	3 / 3	THR A   5 PRO A   8 THR A   7	THR  A   5 ( 0.8A) PRO  A   8 ( 1.1A) THR  A   7 ( 0.8A)	0.73A	1dscC-5w0aA: undetectable	1dscC-5w0aA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSC_C_DVAC8_0 (ACTINOMYCIN D)	5w0a	GLUCANASE (Trichoderma harzianum)	3 / 3	THR A   7 THR A   5 PRO A   8	THR  A   7 ( 0.8A) THR  A   5 ( 0.8A) PRO  A   8 ( 1.1A)	0.74A	1dscC-5w0aA: undetectable	1dscC-5w0aA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSD_C_DVAC2_0 (ACTINOMYCIN D)	3d9a	HEAVY CHAIN OF HYHEL10 ANTIBODY FRAGMENT (FAB) (Mus musculus)	4 / 4	THR H 417 PRO H 447 THR H 416 PRO H 418	THR  H 417 ( 0.8A) PRO  H 447 ( 1.1A) THR  H 416 ( 0.8A) PRO  H 418 ( 1.1A)	1.33A	1dsdC-3d9aH: undetectable	1dsdC-3d9aH: 13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSD_C_DVAC8_0 (ACTINOMYCIN D)	3d9a	HEAVY CHAIN OF HYHEL10 ANTIBODY FRAGMENT (FAB) (Mus musculus)	4 / 4	THR H 417 PRO H 447 THR H 416 PRO H 418	THR  H 417 ( 0.8A) PRO  H 447 ( 1.1A) THR  H 416 ( 0.8A) PRO  H 418 ( 1.1A)	1.33A	1dsdC-3d9aH: undetectable	1dsdC-3d9aH: 13.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DTL_A_BEPA206_1 (CARDIAC TROPONIN C)	4gow	CALMODULIN (Homo sapiens)	4 / 8	MET D  36 GLN D  41 PRO D  43 GLU D  47	MET  D  36 ( 0.0A) GLN  D  41 ( 0.6A) PRO  D  43 ( 1.1A) GLU  D  47 ( 0.5A)	1.06A	1dtlA-4gowD: 12.2	1dtlA-4gowD: 53.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E7C_A_HLTA4004_1 (SERUM ALBUMIN)	2igw	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE 3 (Caenorhabditis elegans)	4 / 4	VAL A 104 PHE A 120 SER A 106 VAL A 135	None PRO  A 202 (-3.6A) None None	1.33A	1e7cA-2igwA: undetectable	1e7cA-2igwA: 14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E7W_A_MTXA301_1 (PTERIDINE REDUCTASE)	3p9w	HUMAN VEGF (Homo sapiens)	5 / 12	PRO B  41 LEU B 108 LEU B  18 LEU B  82 ASP B  86	PRO  B  41 ( 1.1A) LEU  B 108 ( 0.6A) LEU  B  18 ( 0.5A) LEU  B  82 ( 0.5A) ASP  B  86 ( 0.5A)	1.26A	1e7wA-3p9wB: undetectable	1e7wA-3p9wB: 19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_A_GLYA1292_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	4 / 8	SER A1272 SER A1122 HIS A1173 PHE A1216	PRO  A1602 (-3.3A) None PRO  A1602 ( 4.5A) PRO  A1602 (-4.3A)	1.13A	1eqbA-5vadA: undetectable 1eqbB-5vadA: undetectable	1eqbA-5vadA: 22.81 1eqbB-5vadA: 22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_B_GLYB2292_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	4 / 8	PHE A1216 SER A1272 SER A1122 HIS A1173	PRO  A1602 (-4.3A) PRO  A1602 (-3.3A) None PRO  A1602 ( 4.5A)	1.13A	1eqbA-5vadA: undetectable 1eqbB-5vadA: undetectable	1eqbA-5vadA: 22.81 1eqbB-5vadA: 22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_C_GLYC3292_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	4 / 8	SER A1272 SER A1122 HIS A1173 PHE A1216	PRO  A1602 (-3.3A) None PRO  A1602 ( 4.5A) PRO  A1602 (-4.3A)	1.14A	1eqbC-5vadA: undetectable 1eqbD-5vadA: undetectable	1eqbC-5vadA: 22.81 1eqbD-5vadA: 22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_D_GLYD4292_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	4 / 8	PHE A1216 SER A1272 SER A1122 HIS A1173	PRO  A1602 (-4.3A) PRO  A1602 (-3.3A) None PRO  A1602 ( 4.5A)	1.13A	1eqbC-5vadA: undetectable 1eqbD-5vadA: undetectable	1eqbC-5vadA: 22.81 1eqbD-5vadA: 22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FJA_C_DVAC8_0 (ACTINOMYCIN D)	3gle	PILIN (Streptococcus pyogenes)	3 / 3	THR A  50 THR A  84 PRO A  48	THR  A  50 ( 0.8A) THR  A  84 ( 0.8A) PRO  A  48 ( 1.1A)	0.79A	1fjaC-3gleA: undetectable	1fjaC-3gleA: 9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FJA_C_DVAC8_0 (ACTINOMYCIN D)	5w0a	GLUCANASE (Trichoderma harzianum)	3 / 3	THR A   7 THR A   5 PRO A   8	THR  A   7 ( 0.8A) THR  A   5 ( 0.8A) PRO  A   8 ( 1.1A)	0.78A	1fjaC-5w0aA: undetectable	1fjaC-5w0aA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FJA_D_DVAD8_0 (ACTINOMYCIN D)	3gle	PILIN (Streptococcus pyogenes)	3 / 3	THR A  50 THR A  84 PRO A  48	THR  A  50 ( 0.8A) THR  A  84 ( 0.8A) PRO  A  48 ( 1.1A)	0.79A	1fjaD-3gleA: undetectable	1fjaD-3gleA: 9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FJA_D_DVAD8_0 (ACTINOMYCIN D)	5w0a	GLUCANASE (Trichoderma harzianum)	3 / 3	THR A   7 THR A   5 PRO A   8	THR  A   7 ( 0.8A) THR  A   5 ( 0.8A) PRO  A   8 ( 1.1A)	0.77A	1fjaD-5w0aA: undetectable	1fjaD-5w0aA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GSE_B_EAAB224_1 (GLUTATHIONE TRANSFERASE)	2vbf	BRANCHED-CHAIN ALPHA-KETOACID DECARBOXYLASE (Lactococcus lactis)	6 / 12	ARG A 134 PRO A 159 VAL A  93 LEU A  83 ALA A  79 PHE A  68	ARG  A 134 ( 0.6A) PRO  A 159 ( 1.1A) VAL  A  93 ( 0.6A) LEU  A  83 ( 0.6A) ALA  A  79 ( 0.0A) PHE  A  68 ( 1.3A)	1.44A	1gseB-2vbfA: undetectable	1gseB-2vbfA: 19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1H4O_A_BEZA1162_0 (PEROXIREDOXIN 5)	4kqn	D-HYDANTOINASE (Bacillus sp. AR9)	5 / 10	PRO A  57 LEU A 375 PHE A 376 THR A 311 GLY A 261	PRO  A  57 ( 1.1A) LEU  A 375 ( 0.6A) PHE  A 376 ( 1.3A) THR  A 311 ( 0.8A) GLY  A 261 ( 0.0A)	0.92A	1h4oA-4kqnA: undetectable 1h4oB-4kqnA: undetectable	1h4oA-4kqnA: 17.39 1h4oB-4kqnA: 17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1I3W_E_DVAE2_0 (ACTINOMYCIN D)	5w0a	GLUCANASE (Trichoderma harzianum)	3 / 3	THR A   5 PRO A   8 THR A   7	THR  A   5 ( 0.8A) PRO  A   8 ( 1.1A) THR  A   7 ( 0.8A)	0.88A	1i3wE-5w0aA: undetectable	1i3wE-5w0aA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1I3W_E_DVAE8_0 (ACTINOMYCIN D)	5w0a	GLUCANASE (Trichoderma harzianum)	3 / 3	THR A   7 THR A   5 PRO A   8	THR  A   7 ( 0.8A) THR  A   5 ( 0.8A) PRO  A   8 ( 1.1A)	0.87A	1i3wE-5w0aA: undetectable	1i3wE-5w0aA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1I3W_G_DVAG8_0 (ACTINOMYCIN D)	5w0a	GLUCANASE (Trichoderma harzianum)	3 / 3	THR A   7 THR A   5 PRO A   8	THR  A   7 ( 0.8A) THR  A   5 ( 0.8A) PRO  A   8 ( 1.1A)	0.83A	1i3wG-5w0aA: undetectable	1i3wG-5w0aA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1I3W_H_DVAH8_0 (ACTINOMYCIN D)	5w0a	GLUCANASE (Trichoderma harzianum)	3 / 3	THR A   7 THR A   5 PRO A   8	THR  A   7 ( 0.8A) THR  A   5 ( 0.8A) PRO  A   8 ( 1.1A)	0.83A	1i3wH-5w0aA: undetectable	1i3wH-5w0aA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ILQ_C_ACAC7_1 (INTERLEUKIN-8 PRECURSOR INTERLEUKIN-8 RECEPTOR A)	4yzr	POLYKETIDE BIOSYNTHESIS CYTOCHROME P450 PKSS (Bacillus subtilis)	4 / 6	HIS A  99 ASP A  95 ASP A  65 PRO A  97	HIS  A  99 (-1.0A) ASP  A  95 ( 0.6A) ASP  A  65 ( 0.6A) PRO  A  97 ( 1.0A)	1.49A	1ilqA-4yzrA: undetectable 1ilqC-4yzrA: undetectable	1ilqA-4yzrA: 13.02 1ilqC-4yzrA: 5.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JGS_A_SALA256_1 (MULTIPLE ANTIBIOTIC RESISTANCE PROTEIN MARR)	2ogs	THERMOSTABLE CARBOXYLESTERASE EST50 (Geobacillus stearothermophil us)	4 / 7	PRO A 100 VAL A 131 LEU A 102 THR A 189	PRO  A 100 ( 1.1A) VAL  A 131 ( 0.6A) LEU  A 102 ( 0.6A) THR  A 189 ( 0.8A)	0.88A	1jgsA-2ogsA: undetectable	1jgsA-2ogsA: 15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KNY_B_KANB559_1 (KANAMYCIN NUCLEOTIDYLTRANSFERA SE)	3e2s	PROLINE DEHYDROGENASE (Escherichia coli)	4 / 8	GLU A 289 LYS A 329 SER A 440 ASP A 439	None PRO  A   1 (-2.8A) None None	1.18A	1knyA-3e2sA: undetectable 1knyB-3e2sA: undetectable	1knyA-3e2sA: 18.61 1knyB-3e2sA: 18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L7F_A_BCZA801_1 (NEURAMINIDASE)	4p7w	L-PROLINE CIS-4-HYDROXYLASE (Mesorhizobium japonicum)	3 / 3	ARG A  93 ARG A  56 ARG A 118	PRO  A 303 (-2.5A) None PRO  A 303 ( 2.9A)	0.80A	1l7fA-4p7wA: undetectable	1l7fA-4p7wA: 19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L7H_A_BCZA801_1 (NEURAMINIDASE)	4p7w	L-PROLINE CIS-4-HYDROXYLASE (Mesorhizobium japonicum)	3 / 3	ARG A  93 ARG A  56 ARG A 118	PRO  A 303 (-2.5A) None PRO  A 303 ( 2.9A)	0.81A	1l7hA-4p7wA: undetectable	1l7hA-4p7wA: 19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQT_A_ACTA1871_0 (FPRA)	1gc7	RADIXIN (Mus musculus)	4 / 7	PRO A  86 ALA A  82 PHE A  45 PHE A  44	PRO  A  86 ( 1.1A) ALA  A  82 ( 0.0A) PHE  A  45 ( 1.3A) PHE  A  44 ( 1.3A)	1.19A	1lqtA-1gc7A: undetectable	1lqtA-1gc7A: 22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQU_A_ACTA1428_0 (FPRA)	1gc7	RADIXIN (Mus musculus)	4 / 7	PRO A  86 ALA A  82 PHE A  45 PHE A  44	PRO  A  86 ( 1.1A) ALA  A  82 ( 0.0A) PHE  A  45 ( 1.3A) PHE  A  44 ( 1.3A)	1.19A	1lquA-1gc7A: undetectable	1lquA-1gc7A: 22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MCN_P_DHIP1_0 (IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) PEPTIDE N-ACETYL-D-HIS-L-PRO -NH2)	3sag	EXOSOME COMPONENT 10 (Homo sapiens)	3 / 3	PHE A 198 TYR A 382 PRO A 200	PHE  A 198 ( 1.3A) TYR  A 382 ( 1.3A) PRO  A 200 ( 1.1A)	1.15A	1mcnA-3sagA: undetectable 1mcnB-3sagA: undetectable 1mcnP-3sagA: undetectable	1mcnA-3sagA: 17.45 1mcnB-3sagA: 17.45 1mcnP-3sagA: 2.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MCN_P_DHIP1_0 (IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) PEPTIDE N-ACETYL-D-HIS-L-PRO -NH2)	6gef	TYPE IV SECRETION SYSTEM PROTEIN DOTB (Yersinia pseudotuberculos is)	3 / 3	PHE A  21 TYR A  15 PRO A  18	PHE  A  21 ( 1.3A) TYR  A  15 ( 1.3A) PRO  A  18 ( 1.1A)	1.09A	1mcnA-6gefA: undetectable 1mcnB-6gefA: undetectable 1mcnP-6gefA: undetectable	1mcnA-6gefA: undetectable 1mcnB-6gefA: undetectable 1mcnP-6gefA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MNV_D_DVAD2_0 (ACTINOMYCIN D)	5w0a	GLUCANASE (Trichoderma harzianum)	3 / 3	THR A   5 PRO A   8 THR A   7	THR  A   5 ( 0.8A) PRO  A   8 ( 1.1A) THR  A   7 ( 0.8A)	0.84A	1mnvD-5w0aA: undetectable	1mnvD-5w0aA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NV8_A_SAMA300_0 (HEMK PROTEIN)	1omo	ALANINE DEHYDROGENASE (Archaeoglobus fulgidus)	5 / 12	ILE A 131 GLY A 132 GLY A 134 VAL A 158 PRO A 196	ILE  A 131 ( 0.7A) GLY  A 132 ( 0.0A) GLY  A 134 (-0.0A) VAL  A 158 (-0.6A) PRO  A 196 (-1.1A)	1.07A	1nv8A-1omoA: 5.6	1nv8A-1omoA: 24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NV8_B_SAMB301_0 (HEMK PROTEIN)	1omo	ALANINE DEHYDROGENASE (Archaeoglobus fulgidus)	5 / 12	ILE A 131 GLY A 132 GLY A 134 VAL A 158 PRO A 196	ILE  A 131 ( 0.7A) GLY  A 132 ( 0.0A) GLY  A 134 (-0.0A) VAL  A 158 (-0.6A) PRO  A 196 (-1.1A)	1.02A	1nv8B-1omoA: 5.4	1nv8B-1omoA: 24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NV8_B_SAMB301_0 (HEMK PROTEIN)	4kqn	D-HYDANTOINASE (Bacillus sp. AR9)	5 / 12	ILE A  55 GLY A  54 GLY A  85 ILE A 118 PRO A  52	ILE  A  55 ( 0.6A) GLY  A  54 ( 0.0A) GLY  A  85 ( 0.0A) ILE  A 118 ( 0.7A) PRO  A  52 ( 1.1A)	1.06A	1nv8B-4kqnA: undetectable	1nv8B-4kqnA: 22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NW5_A_SAMA401_0 (MODIFICATION METHYLASE RSRI)	2vbf	BRANCHED-CHAIN ALPHA-KETOACID DECARBOXYLASE (Lactococcus lactis)	5 / 12	ASP A 274 PRO A 235 LYS A 342 SER A 265 ALA A 273	ASP  A 274 ( 0.6A) PRO  A 235 ( 1.1A) LYS  A 342 ( 0.0A) SER  A 265 ( 0.0A) ALA  A 273 ( 0.0A)	1.27A	1nw5A-2vbfA: undetectable	1nw5A-2vbfA: 20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ONI_B_BEZB503_0 (14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN)	3e2s	PROLINE DEHYDROGENASE (Escherichia coli)	4 / 6	ARG A 555 ALA A 436 TYR A 552 GLU A 559	PRO  A   1 (-3.8A) FAD  A2001 (-3.3A) PRO  A   1 (-4.7A) FAD  A2001 (-2.8A)	1.22A	1oniB-3e2sA: undetectable 1oniC-3e2sA: undetectable	1oniB-3e2sA: 15.46 1oniC-3e2sA: 15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ONI_F_BEZF511_0 (14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN)	3e2s	PROLINE DEHYDROGENASE (Escherichia coli)	4 / 5	TYR A 552 GLU A 559 ARG A 555 ALA A 436	PRO  A   1 (-4.7A) FAD  A2001 (-2.8A) PRO  A   1 (-3.8A) FAD  A2001 (-3.3A)	1.21A	1oniE-3e2sA: 0.8 1oniF-3e2sA: 0.7	1oniE-3e2sA: 15.46 1oniF-3e2sA: 15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OVF_B_DVAB2_0 (ACTINOMYCIN D)	5w0a	GLUCANASE (Trichoderma harzianum)	3 / 3	THR A   5 PRO A   8 THR A   7	THR  A   5 ( 0.8A) PRO  A   8 ( 1.1A) THR  A   7 ( 0.8A)	0.82A	1ovfB-5w0aA: undetectable	1ovfB-5w0aA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QFI_B_DVAB8_0 (ACTINOMYCIN X2)	2ogs	THERMOSTABLE CARBOXYLESTERASE EST50 (Geobacillus stearothermophil us)	3 / 3	THR A 317 THR A 315 PRO A 319	THR  A 317 ( 0.8A) THR  A 315 ( 0.8A) PRO  A 319 ( 1.1A)	0.86A	1qfiB-2ogsA: undetectable	1qfiB-2ogsA: 2.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RS7_A_ACTA860_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	4rdc	AMINO ACID/AMIDE ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN, HAAT FAMILY (Trichormus variabilis)	4 / 5	GLY A 158 ILE A 159 VAL A 173 SER A 132	None None None PRO  A 501 (-2.6A)	1.16A	1rs7A-4rdcA: undetectable	1rs7A-4rdcA: 20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RXC_B_URFB2011_1 (URIDINE PHOSPHORYLASE)	5ep8	PYRIMIDINE-NUCLEOSID E PHOSPHORYLASE (Bacillus subtilis)	4 / 8	GLY A 355 ILE A 247 VAL A  87 PRO A 242	GLY  A 355 ( 0.0A) ILE  A 247 ( 0.6A) VAL  A  87 ( 0.6A) PRO  A 242 ( 1.1A)	0.97A	1rxcB-5ep8A: 3.4	1rxcB-5ep8A: 22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RXC_C_URFC2081_1 (URIDINE PHOSPHORYLASE)	5ep8	PYRIMIDINE-NUCLEOSID E PHOSPHORYLASE (Bacillus subtilis)	4 / 7	GLY A 355 ILE A 247 VAL A  87 PRO A 242	GLY  A 355 ( 0.0A) ILE  A 247 ( 0.6A) VAL  A  87 ( 0.6A) PRO  A 242 ( 1.1A)	0.95A	1rxcC-5ep8A: 3.4	1rxcC-5ep8A: 22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RXC_D_URFD2021_1 (URIDINE PHOSPHORYLASE)	5ep8	PYRIMIDINE-NUCLEOSID E PHOSPHORYLASE (Bacillus subtilis)	4 / 7	GLY A 355 ILE A 247 VAL A  87 PRO A 242	GLY  A 355 ( 0.0A) ILE  A 247 ( 0.6A) VAL  A  87 ( 0.6A) PRO  A 242 ( 1.1A)	0.94A	1rxcD-5ep8A: 3.2	1rxcD-5ep8A: 22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RXC_E_URFE2031_1 (URIDINE PHOSPHORYLASE)	5ep8	PYRIMIDINE-NUCLEOSID E PHOSPHORYLASE (Bacillus subtilis)	4 / 8	GLY A 355 ILE A 247 VAL A  87 PRO A 242	GLY  A 355 ( 0.0A) ILE  A 247 ( 0.6A) VAL  A  87 ( 0.6A) PRO  A 242 ( 1.1A)	0.96A	1rxcE-5ep8A: 3.4	1rxcE-5ep8A: 22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RXC_F_URFF2001_1 (URIDINE PHOSPHORYLASE)	5ep8	PYRIMIDINE-NUCLEOSID E PHOSPHORYLASE (Bacillus subtilis)	4 / 7	GLY A 355 ILE A 247 VAL A  87 PRO A 242	GLY  A 355 ( 0.0A) ILE  A 247 ( 0.6A) VAL  A  87 ( 0.6A) PRO  A 242 ( 1.1A)	1.00A	1rxcF-5ep8A: 3.4	1rxcF-5ep8A: 22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RXC_K_URFK2061_1 (URIDINE PHOSPHORYLASE)	5ep8	PYRIMIDINE-NUCLEOSID E PHOSPHORYLASE (Bacillus subtilis)	4 / 8	GLY A 355 ILE A 247 VAL A  87 PRO A 242	GLY  A 355 ( 0.0A) ILE  A 247 ( 0.6A) VAL  A  87 ( 0.6A) PRO  A 242 ( 1.1A)	0.97A	1rxcK-5ep8A: 3.1	1rxcK-5ep8A: 22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RXC_L_URFL2071_1 (URIDINE PHOSPHORYLASE)	5ep8	PYRIMIDINE-NUCLEOSID E PHOSPHORYLASE (Bacillus subtilis)	4 / 7	GLY A 355 ILE A 247 VAL A  87 PRO A 242	GLY  A 355 ( 0.0A) ILE  A 247 ( 0.6A) VAL  A  87 ( 0.6A) PRO  A 242 ( 1.1A)	0.98A	1rxcL-5ep8A: 3.2	1rxcL-5ep8A: 22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SQF_A_SAMA430_0 (SUN PROTEIN)	2nvv	ACETYL-COA HYDROLASE/TRANSFERAS E FAMILY PROTEIN (Porphyromonas gingivalis)	5 / 12	GLY A 141 GLY A  30 ASP A 381 GLY A 378 PRO A  82	GLY  A 141 ( 0.0A) GLY  A  30 ( 0.0A) ASP  A 381 ( 0.6A) GLY  A 378 ( 0.0A) PRO  A  82 ( 1.1A)	0.96A	1sqfA-2nvvA: undetectable	1sqfA-2nvvA: 21.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1TJ2_A_ACTA2002_0 (BIFUNCTIONAL PUTA PROTEIN)	3e2s	PROLINE DEHYDROGENASE (Escherichia coli)	5 / 5	LYS A 329 ALA A 436 TYR A 552 ARG A 555 ARG A 556	PRO  A   1 (-2.8A) FAD  A2001 (-3.3A) PRO  A   1 (-4.7A) PRO  A   1 (-3.8A) PRO  A   1 (-2.8A)	0.18A	1tj2A-3e2sA: 69.1	1tj2A-3e2sA: 93.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UNJ_L_DVAL2_0 (7-AMINO-ACTINOMYCIN D)	5w0a	GLUCANASE (Trichoderma harzianum)	3 / 3	THR A   5 PRO A   8 THR A   7	THR  A   5 ( 0.8A) PRO  A   8 ( 1.1A) THR  A   7 ( 0.8A)	0.85A	1unjL-5w0aA: undetectable	1unjL-5w0aA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UNJ_L_DVAL8_0 (7-AMINO-ACTINOMYCIN D)	5w0a	GLUCANASE (Trichoderma harzianum)	3 / 3	THR A   7 THR A   5 PRO A   8	THR  A   7 ( 0.8A) THR  A   5 ( 0.8A) PRO  A   8 ( 1.1A)	0.83A	1unjL-5w0aA: undetectable	1unjL-5w0aA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UNJ_R_DVAR2_0 (7-AMINO-ACTINOMYCIN D)	5w0a	GLUCANASE (Trichoderma harzianum)	3 / 3	THR A   5 PRO A   8 THR A   7	THR  A   5 ( 0.8A) PRO  A   8 ( 1.1A) THR  A   7 ( 0.8A)	0.85A	1unjR-5w0aA: undetectable	1unjR-5w0aA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UNJ_W_DVAW8_0 (7-AMINO-ACTINOMYCIN D)	5w0a	GLUCANASE (Trichoderma harzianum)	3 / 3	THR A   7 THR A   5 PRO A   8	THR  A   7 ( 0.8A) THR  A   5 ( 0.8A) PRO  A   8 ( 1.1A)	0.79A	1unjW-5w0aA: undetectable	1unjW-5w0aA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UNJ_X_DVAX2_0 (7-AMINO-ACTINOMYCIN D)	5w0a	GLUCANASE (Trichoderma harzianum)	3 / 3	THR A   5 PRO A   8 THR A   7	THR  A   5 ( 0.8A) PRO  A   8 ( 1.1A) THR  A   7 ( 0.8A)	0.86A	1unjX-5w0aA: undetectable	1unjX-5w0aA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UNM_E_DVAE2_0 (7-AMINOACTINOMYCIN D)	5w0a	GLUCANASE (Trichoderma harzianum)	3 / 3	THR A   5 PRO A   8 THR A   7	THR  A   5 ( 0.8A) PRO  A   8 ( 1.1A) THR  A   7 ( 0.8A)	0.84A	1unmE-5w0aA: undetectable	1unmE-5w0aA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UNM_E_DVAE8_0 (7-AMINOACTINOMYCIN D)	5w0a	GLUCANASE (Trichoderma harzianum)	3 / 3	THR A   7 THR A   5 PRO A   8	THR  A   7 ( 0.8A) THR  A   5 ( 0.8A) PRO  A   8 ( 1.1A)	0.80A	1unmE-5w0aA: undetectable	1unmE-5w0aA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UNM_F_DVAF2_0 (7-AMINOACTINOMYCIN D)	5w0a	GLUCANASE (Trichoderma harzianum)	3 / 3	THR A   5 PRO A   8 THR A   7	THR  A   5 ( 0.8A) PRO  A   8 ( 1.1A) THR  A   7 ( 0.8A)	0.83A	1unmF-5w0aA: undetectable	1unmF-5w0aA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UNM_F_DVAF8_0 (7-AMINOACTINOMYCIN D)	5w0a	GLUCANASE (Trichoderma harzianum)	3 / 3	THR A   7 THR A   5 PRO A   8	THR  A   7 ( 0.8A) THR  A   5 ( 0.8A) PRO  A   8 ( 1.1A)	0.85A	1unmF-5w0aA: undetectable	1unmF-5w0aA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1USQ_A_CLMA1143_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	4ki5	MURINE MONOCLONAL G99 FAB HEAVY CHAIN (Mus musculus)	5 / 7	GLY E  54 PRO E  53 THR E  58 ILE E  51 GLY E  56	GLY  E  54 ( 0.0A) PRO  E  53 ( 1.1A) THR  E  58 ( 0.8A) ILE  E  51 ( 0.7A) GLY  E  56 ( 0.0A)	1.10A	1usqA-4ki5E: undetectable	1usqA-4ki5E: 20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1USQ_B_CLMB1143_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	4ki5	MURINE MONOCLONAL G99 FAB HEAVY CHAIN (Mus musculus)	4 / 6	GLY E  54 PRO E  53 ILE E  51 GLY E  56	GLY  E  54 ( 0.0A) PRO  E  53 ( 1.1A) ILE  E  51 ( 0.7A) GLY  E  56 ( 0.0A)	0.77A	1usqB-4ki5E: undetectable	1usqB-4ki5E: 20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1USQ_C_CLMC1143_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	4ki5	MURINE MONOCLONAL G99 FAB HEAVY CHAIN (Mus musculus)	4 / 6	GLY E  54 PRO E  53 ILE E  51 GLY E  56	GLY  E  54 ( 0.0A) PRO  E  53 ( 1.1A) ILE  E  51 ( 0.7A) GLY  E  56 ( 0.0A)	0.77A	1usqC-4ki5E: undetectable	1usqC-4ki5E: 20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1USQ_D_CLMD1142_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	4ki5	MURINE MONOCLONAL G99 FAB HEAVY CHAIN (Mus musculus)	4 / 6	GLY E  54 PRO E  53 ILE E  51 GLY E  56	GLY  E  54 ( 0.0A) PRO  E  53 ( 1.1A) ILE  E  51 ( 0.7A) GLY  E  56 ( 0.0A)	0.77A	1usqD-4ki5E: undetectable	1usqD-4ki5E: 20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1USQ_E_CLME1143_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	4ki5	MURINE MONOCLONAL G99 FAB HEAVY CHAIN (Mus musculus)	4 / 6	GLY E  54 PRO E  53 ILE E  51 GLY E  56	GLY  E  54 ( 0.0A) PRO  E  53 ( 1.1A) ILE  E  51 ( 0.7A) GLY  E  56 ( 0.0A)	0.77A	1usqE-4ki5E: undetectable	1usqE-4ki5E: 20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WG8_B_SAMB3141_0 (PREDICTED S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE)	2ixq	PROTEIN AFAD (Escherichia coli)	5 / 12	PRO A  86 GLY A  68 GLY A  69 GLY A  71 GLN A  44	PRO  A  86 ( 1.0A) GLY  A  68 ( 0.0A) GLY  A  69 ( 0.0A) GLY  A  71 ( 0.0A) GLN  A  44 ( 0.6A)	1.04A	1wg8B-2ixqA: undetectable	1wg8B-2ixqA: 18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WSV_A_THHA3001_1 (AMINOMETHYLTRANSFERA SE)	3e2s	PROLINE DEHYDROGENASE (Escherichia coli)	3 / 3	ASP A 370 GLU A 559 TYR A 466	PRO  A   1 ( 3.8A) FAD  A2001 (-2.8A) None	0.83A	1wsvA-3e2sA: undetectable	1wsvA-3e2sA: 22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1X70_A_715A801_1 (DIPEPTIDYL PEPTIDASE IV)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	9 / 12	ARG A 106 GLU A 208 GLU A 209 TYR A 527 VAL A 639 TYR A 645 TYR A 649 ASN A 691 VAL A 692	ILE  A 801 (-4.2A) ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-4.7A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A) None	0.75A	1x70A-5yp3A: 34.6	1x70A-5yp3A: 8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1X70_A_715A801_1 (DIPEPTIDYL PEPTIDASE IV)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	9 / 12	GLU A 208 GLU A 209 TYR A 527 VAL A 639 TYR A 645 TYR A 649 ASN A 691 VAL A 692 HIS A 721	ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-4.7A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A) None ILE  A 801 (-4.5A)	0.42A	1x70A-5yp3A: 34.6	1x70A-5yp3A: 8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1X70_B_715B801_1 (DIPEPTIDYL PEPTIDASE IV)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	9 / 12	ARG A 106 GLU A 208 GLU A 209 SER A 613 VAL A 639 TYR A 645 TYR A 649 ASN A 691 VAL A 692	ILE  A 801 (-4.2A) ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A) None	0.78A	1x70B-5yp3A: 34.5	1x70B-5yp3A: 8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1X70_B_715B801_1 (DIPEPTIDYL PEPTIDASE IV)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	9 / 12	GLU A 208 GLU A 209 SER A 613 VAL A 639 TYR A 645 TYR A 649 ASN A 691 VAL A 692 HIS A 721	ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A) None ILE  A 801 (-4.5A)	0.49A	1x70B-5yp3A: 34.5	1x70B-5yp3A: 8.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1XMU_A_ROFA101_0 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B)	3sl5	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D (Homo sapiens)	12 / 12	TYR A 159 HIS A 160 ASP A 318 LEU A 319 PRO A 322 TYR A 329 TRP A 332 ILE A 336 PHE A 340 MET A 357 SER A 368 PHE A 372	TYR  A 159 (-1.3A) HIS  A 160 ( 1.0A) ASP  A 318 (-0.5A) LEU  A 319 ( 0.6A) PRO  A 322 (-1.1A) TYR  A 329 (-1.3A) TRP  A 332 ( 0.5A) ILE  A 336 ( 0.4A) PHE  A 340 (-1.3A) MET  A 357 (-0.0A) SER  A 368 (-0.0A) PHE  A 372 (-1.3A)	0.61A	1xmuA-3sl5A: 51.4	1xmuA-3sl5A: 84.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1XMU_B_ROFB102_0 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B)	3sl5	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D (Homo sapiens)	12 / 12	TYR A 159 HIS A 160 MET A 273 ASP A 318 LEU A 319 PRO A 322 TYR A 329 TRP A 332 ILE A 336 PHE A 340 MET A 357 SER A 368	TYR  A 159 (-1.3A) HIS  A 160 ( 1.0A) MET  A 273 (-0.0A) ASP  A 318 (-0.5A) LEU  A 319 ( 0.6A) PRO  A 322 (-1.1A) TYR  A 329 (-1.3A) TRP  A 332 ( 0.5A) ILE  A 336 ( 0.4A) PHE  A 340 (-1.3A) MET  A 357 (-0.0A) SER  A 368 (-0.0A)	0.44A	1xmuB-3sl5A: 51.1	1xmuB-3sl5A: 84.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1XOQ_A_ROFA502_0 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D)	3sl5	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D (Homo sapiens)	11 / 12	TYR A 159 HIS A 160 MET A 273 ASP A 318 LEU A 319 PRO A 322 TYR A 329 THR A 333 ILE A 336 MET A 357 SER A 368	TYR  A 159 (-1.3A) HIS  A 160 ( 1.0A) MET  A 273 (-0.0A) ASP  A 318 (-0.5A) LEU  A 319 ( 0.6A) PRO  A 322 (-1.1A) TYR  A 329 (-1.3A) THR  A 333 ( 0.8A) ILE  A 336 ( 0.4A) MET  A 357 (-0.0A) SER  A 368 (-0.0A)	0.54A	1xoqA-3sl5A: 53.5	1xoqA-3sl5A: 94.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1XOQ_A_ROFA502_0 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D)	3sl5	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D (Homo sapiens)	11 / 12	TYR A 159 HIS A 160 MET A 273 ASP A 318 LEU A 319 PRO A 322 TYR A 329 THR A 333 ILE A 336 SER A 368 PHE A 372	TYR  A 159 (-1.3A) HIS  A 160 ( 1.0A) MET  A 273 (-0.0A) ASP  A 318 (-0.5A) LEU  A 319 ( 0.6A) PRO  A 322 (-1.1A) TYR  A 329 (-1.3A) THR  A 333 ( 0.8A) ILE  A 336 ( 0.4A) SER  A 368 (-0.0A) PHE  A 372 (-1.3A)	0.52A	1xoqA-3sl5A: 53.5	1xoqA-3sl5A: 94.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1XOQ_B_ROFB501_0 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D)	3sl5	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D (Homo sapiens)	11 / 12	TYR A 159 HIS A 160 ASP A 318 LEU A 319 PRO A 322 TYR A 329 TRP A 332 THR A 333 ILE A 336 MET A 357 SER A 368	TYR  A 159 (-1.3A) HIS  A 160 ( 1.0A) ASP  A 318 (-0.5A) LEU  A 319 ( 0.6A) PRO  A 322 (-1.1A) TYR  A 329 (-1.3A) TRP  A 332 ( 0.5A) THR  A 333 ( 0.8A) ILE  A 336 ( 0.4A) MET  A 357 (-0.0A) SER  A 368 (-0.0A)	0.49A	1xoqB-3sl5A: 53.4	1xoqB-3sl5A: 94.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1XOQ_B_ROFB501_0 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D)	3sl5	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D (Homo sapiens)	11 / 12	TYR A 159 HIS A 160 ASP A 318 LEU A 319 PRO A 322 TYR A 329 TRP A 332 THR A 333 ILE A 336 SER A 368 PHE A 372	TYR  A 159 (-1.3A) HIS  A 160 ( 1.0A) ASP  A 318 (-0.5A) LEU  A 319 ( 0.6A) PRO  A 322 (-1.1A) TYR  A 329 (-1.3A) TRP  A 332 ( 0.5A) THR  A 333 ( 0.8A) ILE  A 336 ( 0.4A) SER  A 368 (-0.0A) PHE  A 372 (-1.3A)	0.50A	1xoqB-3sl5A: 53.4	1xoqB-3sl5A: 94.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z9H_D_IMND476_1 (MEMBRANE-ASSOCIATED PROSTAGLANDIN E SYNTHASE-2)	2j5b	TYROSYL-TRNA SYNTHETASE (Acanthamoeba polyphaga mimivirus)	5 / 12	PRO A 258 ILE A 259 VAL A 303 ILE A 232 LEU A 267	PRO  A 258 ( 1.1A) ILE  A 259 ( 0.7A) VAL  A 303 ( 0.6A) ILE  A 232 ( 0.7A) LEU  A 267 ( 0.6A)	1.15A	1z9hD-2j5bA: 2.7	1z9hD-2j5bA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZLQ_A_ACTA1502_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	4mwt	LYSOSOMAL PROTECTIVE PROTEIN (Homo sapiens)	4 / 5	PRO A 329 GLY A 105 ASN A 335 GLY A 103	PRO  A 329 ( 1.1A) GLY  A 105 ( 0.0A) ASN  A 335 ( 0.6A) GLY  A 103 ( 0.0A)	1.16A	1zlqA-4mwtA: undetectable	1zlqA-4mwtA: 20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	209D_C_DVAC8_0 (N8-ACTINOMYCIN D)	3gle	PILIN (Streptococcus pyogenes)	3 / 3	THR A  50 THR A  84 PRO A  48	THR  A  50 ( 0.8A) THR  A  84 ( 0.8A) PRO  A  48 ( 1.1A)	0.81A	209dC-3gleA: undetectable	209dC-3gleA: 9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	209D_C_DVAC8_0 (N8-ACTINOMYCIN D)	5w0a	GLUCANASE (Trichoderma harzianum)	3 / 3	THR A   7 THR A   5 PRO A   8	THR  A   7 ( 0.8A) THR  A   5 ( 0.8A) PRO  A   8 ( 1.1A)	0.87A	209dC-5w0aA: undetectable	209dC-5w0aA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AOF_C_FRDC305_1 (POL POLYPROTEIN PEPTIDE INHIBITOR)	5jja	SERINE/THREONINE-PRO TEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM (Homo sapiens)	4 / 5	GLY A 191 PRO A 152 ALA A 155 ILE A 159	GLY  A 191 ( 0.0A) PRO  A 152 ( 1.1A) ALA  A 155 ( 0.0A) ILE  A 159 ( 0.7A)	0.88A	2aofA-5jjaA: undetectable	2aofA-5jjaA: 16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AOF_C_FRDC305_2 (POL POLYPROTEIN PEPTIDE INHIBITOR)	1aoa	T-FIMBRIN (Homo sapiens)	4 / 5	LEU A 306 PRO A 311 ALA A 310 ILE A 309	LEU  A 306 ( 0.6A) PRO  A 311 ( 1.1A) ALA  A 310 ( 0.0A) ILE  A 309 ( 0.3A)	0.90A	2aofB-1aoaA: undetectable	2aofB-1aoaA: 15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AOI_C_FRDC305_2 (POL POLYPROTEIN PEPTIDE INHIBITOR)	4yzr	POLYKETIDE BIOSYNTHESIS CYTOCHROME P450 PKSS (Bacillus subtilis)	4 / 5	LEU A 157 PRO A 150 VAL A 153 ILE A 154	LEU  A 157 ( 0.6A) PRO  A 150 ( 1.1A) VAL  A 153 ( 0.6A) ILE  A 154 ( 0.7A)	1.00A	2aoiB-4yzrA: undetectable	2aoiB-4yzrA: 12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AOI_C_FRDC305_2 (POL POLYPROTEIN PEPTIDE INHIBITOR)	5nks	DIHYDROPYRIMIDINASE- RELATED PROTEIN 4 (Homo sapiens)	4 / 5	LEU A  49 PRO A  52 VAL A  51 ILE A  50	LEU  A  49 ( 0.6A) PRO  A  52 ( 1.1A) VAL  A  51 ( 0.6A) ILE  A  50 ( 0.6A)	1.01A	2aoiB-5nksA: undetectable	2aoiB-5nksA: 9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2E5D_A_NCAA1501_0 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	5dis	SNURPORTIN-1 (Homo sapiens)	4 / 7	ARG C 129 ASP C 187 ASP C 173 TYR C 266	PRO  C 301 (-4.4A) None None None	1.11A	2e5dA-5disC: undetectable 2e5dB-5disC: undetectable	2e5dA-5disC: 20.28 2e5dB-5disC: 20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2E5D_B_NCAB1502_0 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	5dis	SNURPORTIN-1 (Homo sapiens)	4 / 7	ASP C 173 TYR C 266 ARG C 129 ASP C 187	None None PRO  C 301 (-4.4A) None	1.12A	2e5dA-5disC: undetectable 2e5dB-5disC: undetectable	2e5dA-5disC: 20.28 2e5dB-5disC: 20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HDN_B_TACB1888_1 (ELONGATION FACTOR EF-TU)	4kqn	D-HYDANTOINASE (Bacillus sp. AR9)	4 / 5	THR A  87 SER A 369 PRO A  52 SER A 368	THR  A  87 ( 0.8A) SER  A 369 ( 0.0A) PRO  A  52 ( 1.1A) SER  A 368 ( 0.0A)	1.45A	2hdnA-4kqnA: undetectable 2hdnB-4kqnA: 3.2 2hdnD-4kqnA: 3.6	2hdnA-4kqnA: 7.37 2hdnB-4kqnA: 22.64 2hdnD-4kqnA: 22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HDN_D_TACD2888_1 (ELONGATION FACTOR EF-TU)	4kqn	D-HYDANTOINASE (Bacillus sp. AR9)	4 / 5	SER A 368 THR A  87 SER A 369 PRO A  52	SER  A 368 ( 0.0A) THR  A  87 ( 0.8A) SER  A 369 ( 0.0A) PRO  A  52 ( 1.1A)	1.45A	2hdnB-4kqnA: 3.2 2hdnC-4kqnA: undetectable 2hdnD-4kqnA: 3.3	2hdnB-4kqnA: 22.64 2hdnC-4kqnA: 7.37 2hdnD-4kqnA: 22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HJH_B_NCAB901_0 (NAD-DEPENDENT HISTONE DEACETYLASE SIR2)	3r64	NAD DEPENDENT BENZALDEHYDE DEHYDROGENASE (Corynebacterium glutamicum)	4 / 5	ILE A 181 PRO A 183 PHE A 223 VAL A 212	ILE  A 181 ( 0.7A) PRO  A 183 ( 1.1A) PHE  A 223 ( 1.3A) VAL  A 212 ( 0.6A)	1.39A	2hjhB-3r64A: undetectable	2hjhB-3r64A: 20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HRC_A_CHDA703_0 (FERROCHELATASE)	5xlu	GAMMA GLUTAMYL TRANSPEPTIDASE (Bacillus licheniformis)	4 / 4	LEU A 345 PRO A 344 LEU A 348 ARG A 331	LEU  A 345 ( 0.5A) PRO  A 344 ( 1.1A) LEU  A 348 ( 0.5A) ARG  A 331 ( 0.6A)	1.42A	2hrcA-5xluA: undetectable	2hrcA-5xluA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HRE_B_CHDB701_0 (FERROCHELATASE)	3pu5	EXTRACELLULAR SOLUTE-BINDING PROTEIN (Bordetella parapertussis)	3 / 3	LYS A 123 GLY A 263 PRO A 260	LYS  A 123 ( 0.0A) GLY  A 263 ( 0.0A) PRO  A 260 ( 1.1A)	0.95A	2hreB-3pu5A: undetectable	2hreB-3pu5A: 20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HRE_D_CHDD702_0 (FERROCHELATASE)	1vho	ENDOGLUCANASE (Thermotoga maritima)	3 / 3	ARG A 316 GLY A 243 PRO A 244	ARG  A 316 ( 0.6A) GLY  A 243 ( 0.0A) PRO  A 244 ( 1.1A)	0.70A	2hreD-1vhoA: 2.4	2hreD-1vhoA: 23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J9C_C_ACTC1120_0 (HYPOTHETICAL NITROGEN REGULATORY PII-LIKE PROTEIN MJ0059)	4hne	PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2-ALPHA (Homo sapiens)	3 / 3	LYS A 256 TYR A 138 PRO A 153	LYS  A 256 ( 0.0A) TYR  A 138 ( 1.3A) PRO  A 153 ( 1.1A)	1.30A	2j9cC-4hneA: undetectable	2j9cC-4hneA: 15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JJP_A_KLNA413_1 (CYTOCHROME P450 113A1)	5wpi	HSVA (Erwinia amylovora)	5 / 12	PRO A  17 ALA A 352 ALA A 119 PHE A 149 ILE A 152	PRO  A  17 ( 1.1A) ALA  A 352 ( 0.0A) ALA  A 119 ( 0.0A) PHE  A 149 ( 1.3A) ILE  A 152 ( 0.6A)	1.30A	2jjpA-5wpiA: undetectable	2jjpA-5wpiA: 20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JKJ_A_CLMA1141_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	4ki5	MURINE MONOCLONAL G99 FAB HEAVY CHAIN (Mus musculus)	4 / 6	GLY E  54 PRO E  53 ILE E  51 GLY E  56	GLY  E  54 ( 0.0A) PRO  E  53 ( 1.1A) ILE  E  51 ( 0.7A) GLY  E  56 ( 0.0A)	0.84A	2jkjA-4ki5E: undetectable	2jkjA-4ki5E: 20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JKJ_B_CLMB1141_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	4ki5	MURINE MONOCLONAL G99 FAB HEAVY CHAIN (Mus musculus)	4 / 6	GLY E  54 PRO E  53 ILE E  51 GLY E  56	GLY  E  54 ( 0.0A) PRO  E  53 ( 1.1A) ILE  E  51 ( 0.7A) GLY  E  56 ( 0.0A)	0.84A	2jkjB-4ki5E: undetectable	2jkjB-4ki5E: 20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JKJ_C_CLMC1141_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	4ki5	MURINE MONOCLONAL G99 FAB HEAVY CHAIN (Mus musculus)	4 / 6	GLY E  54 PRO E  53 ILE E  51 GLY E  56	GLY  E  54 ( 0.0A) PRO  E  53 ( 1.1A) ILE  E  51 ( 0.7A) GLY  E  56 ( 0.0A)	0.84A	2jkjC-4ki5E: undetectable	2jkjC-4ki5E: 20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JKJ_D_CLMD1142_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	5gpr	CHITINASE (Ostrinia furnacalis)	4 / 5	PRO A 273 PRO A 186 ILE A 185 GLY A 266	PRO  A 273 ( 1.1A) PRO  A 186 ( 1.1A) ILE  A 185 ( 0.7A) GLY  A 266 ( 0.0A)	1.08A	2jkjD-5gprA: undetectable	2jkjD-5gprA: 14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JKJ_F_CLMF1143_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	5gpr	CHITINASE (Ostrinia furnacalis)	4 / 5	PRO A 273 PRO A 186 ILE A 185 GLY A 266	PRO  A 273 ( 1.1A) PRO  A 186 ( 1.1A) ILE  A 185 ( 0.7A) GLY  A 266 ( 0.0A)	1.08A	2jkjF-5gprA: undetectable	2jkjF-5gprA: 14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JKL_A_CLMA1144_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	4ki5	MURINE MONOCLONAL G99 FAB HEAVY CHAIN (Mus musculus)	5 / 7	GLY E  54 PRO E  53 THR E  58 ILE E  51 GLY E  56	GLY  E  54 ( 0.0A) PRO  E  53 ( 1.1A) THR  E  58 ( 0.8A) ILE  E  51 ( 0.7A) GLY  E  56 ( 0.0A)	1.12A	2jklA-4ki5E: undetectable	2jklA-4ki5E: 20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JKL_B_CLMB1144_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	4ki5	MURINE MONOCLONAL G99 FAB HEAVY CHAIN (Mus musculus)	4 / 6	GLY E  54 PRO E  53 ILE E  51 GLY E  56	GLY  E  54 ( 0.0A) PRO  E  53 ( 1.1A) ILE  E  51 ( 0.7A) GLY  E  56 ( 0.0A)	0.83A	2jklB-4ki5E: undetectable	2jklB-4ki5E: 20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JKL_C_CLMC1143_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	4ki5	MURINE MONOCLONAL G99 FAB HEAVY CHAIN (Mus musculus)	5 / 7	GLY E  54 PRO E  53 THR E  58 ILE E  51 GLY E  56	GLY  E  54 ( 0.0A) PRO  E  53 ( 1.1A) THR  E  58 ( 0.8A) ILE  E  51 ( 0.7A) GLY  E  56 ( 0.0A)	1.12A	2jklC-4ki5E: undetectable	2jklC-4ki5E: 20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JKL_D_CLMD1145_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	4ki5	MURINE MONOCLONAL G99 FAB HEAVY CHAIN (Mus musculus)	5 / 7	GLY E  54 PRO E  53 THR E  58 ILE E  51 GLY E  56	GLY  E  54 ( 0.0A) PRO  E  53 ( 1.1A) THR  E  58 ( 0.8A) ILE  E  51 ( 0.7A) GLY  E  56 ( 0.0A)	1.11A	2jklD-4ki5E: undetectable	2jklD-4ki5E: 20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JKL_F_CLMF1143_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	4ki5	MURINE MONOCLONAL G99 FAB HEAVY CHAIN (Mus musculus)	5 / 7	GLY E  54 PRO E  53 THR E  58 ILE E  51 GLY E  56	GLY  E  54 ( 0.0A) PRO  E  53 ( 1.1A) THR  E  58 ( 0.8A) ILE  E  51 ( 0.7A) GLY  E  56 ( 0.0A)	1.11A	2jklF-4ki5E: undetectable	2jklF-4ki5E: 20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NV4_A_SAMA201_0 (UPF0066 PROTEIN AF_0241)	4hne	PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2-ALPHA (Homo sapiens)	5 / 12	ALA A 350 GLN A 426 ASP A 182 PRO A 356 LEU A 184	ALA  A 350 ( 0.0A) GLN  A 426 ( 0.6A) ASP  A 182 ( 0.6A) PRO  A 356 ( 1.1A) LEU  A 184 ( 0.6A)	1.32A	2nv4A-4hneA: undetectable	2nv4A-4hneA: 19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NYU_B_SAMB201_1 (PUTATIVE RIBOSOMAL RNA METHYLTRANSFERASE 2)	1ted	PKS18 (Mycobacterium tuberculosis)	4 / 5	PRO A  99 ALA A 100 ASP A  89 ASP A 104	PRO  A  99 ( 1.1A) ALA  A 100 ( 0.0A) ASP  A  89 ( 0.5A) ASP  A 104 ( 0.6A)	1.19A	2nyuB-1tedA: undetectable	2nyuB-1tedA: 21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PYN_A_1UNA1001_3 (PROTEASE RETROPEPSIN)	2nvv	ACETYL-COA HYDROLASE/TRANSFERAS E FAMILY PROTEIN (Porphyromonas gingivalis)	3 / 3	ASP A 413 THR A 393 PRO A 394	ASP  A 413 (-0.5A) THR  A 393 ( 0.8A) PRO  A 394 ( 1.1A)	0.61A	2pynB-2nvvA: undetectable	2pynB-2nvvA: 12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q64_B_1UNB1001_4 (PROTEASE RETROPEPSIN)	2nvv	ACETYL-COA HYDROLASE/TRANSFERAS E FAMILY PROTEIN (Porphyromonas gingivalis)	3 / 3	ASP A 413 THR A 393 PRO A 394	ASP  A 413 (-0.5A) THR  A 393 ( 0.8A) PRO  A 394 ( 1.1A)	0.60A	2q64B-2nvvA: undetectable	2q64B-2nvvA: 12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q64_B_1UNB1001_4 (PROTEASE RETROPEPSIN)	5c6d	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 (Homo sapiens)	3 / 3	ASP A 722 THR A 707 PRO A 708	ASP  A 722 ( 0.6A) THR  A 707 ( 0.8A) PRO  A 708 ( 1.1A)	0.64A	2q64B-5c6dA: undetectable	2q64B-5c6dA: 15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QAK_A_1UNA1001_4 (PROTEASE RETROPEPSIN)	2nvv	ACETYL-COA HYDROLASE/TRANSFERAS E FAMILY PROTEIN (Porphyromonas gingivalis)	3 / 3	ASP A 413 THR A 393 PRO A 394	ASP  A 413 (-0.5A) THR  A 393 ( 0.8A) PRO  A 394 ( 1.1A)	0.57A	2qakB-2nvvA: undetectable	2qakB-2nvvA: 12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD4_A_CHDA803_0 (FERROCHELATASE)	3gnr	OS03G0212800 PROTEIN (Oryza sativa)	4 / 5	LEU A 135 PRO A 136 LEU A 139 ILE A 151	LEU  A 135 ( 0.6A) PRO  A 136 ( 1.1A) LEU  A 139 ( 0.6A) ILE  A 151 ( 0.4A)	0.81A	2qd4A-3gnrA: undetectable	2qd4A-3gnrA: 21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD5_B_CHDB1104_0 (FERROCHELATASE)	4flx	DNA POLYMERASE 1 (Pyrococcus abyssi)	3 / 3	LEU A 571 PRO A 572 LEU A 575	LEU  A 571 ( 0.5A) PRO  A 572 ( 1.1A) LEU  A 575 ( 0.6A)	0.47A	2qd5B-4flxA: undetectable	2qd5B-4flxA: 18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QEU_B_ACTB141_0 (PUTATIVE CARBOXYMUCONOLACTONE DECARBOXYLASE)	3gnr	OS03G0212800 PROTEIN (Oryza sativa)	3 / 3	PRO A 403 ASN A 401 ARG A 459	PRO  A 403 (-1.1A) ASN  A 401 ( 0.6A) ARG  A 459 ( 0.6A)	1.05A	2qeuB-3gnrA: 1.8	2qeuB-3gnrA: 13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QEU_B_ACTB141_0 (PUTATIVE CARBOXYMUCONOLACTONE DECARBOXYLASE)	4cgu	PROTEIN INTERACTING WITH HSP90 1 (Saccharomyces cerevisiae)	3 / 3	PRO B 265 ASN B 287 ARG B 338	PRO  B 265 ( 1.1A) ASN  B 287 ( 0.6A) ARG  B 338 ( 0.6A)	1.01A	2qeuB-4cguB: undetectable	2qeuB-4cguB: 20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RGU_A_356A901_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	9 / 12	GLU A 208 GLU A 209 TRP A 612 SER A 613 VAL A 639 TYR A 645 TYR A 649 VAL A 692 HIS A 721	ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) None PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) None ILE  A 801 (-4.5A)	0.75A	2rguA-5yp3A: 34.5	2rguA-5yp3A: 8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RGU_A_356A901_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	8 / 12	GLU A 208 GLU A 209 TYR A 527 TRP A 612 SER A 613 VAL A 639 TYR A 645 TYR A 649	ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-4.7A) None PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A)	0.82A	2rguA-5yp3A: 34.5	2rguA-5yp3A: 8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RGU_A_356A901_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	5 / 12	GLU A 208 TYR A 527 SER A 613 VAL A 639 TYR A 645	ILE  A 801 (-3.4A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A)	1.19A	2rguA-5yp3A: 34.5	2rguA-5yp3A: 8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RGU_B_356B902_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	9 / 11	GLU A 208 GLU A 209 TRP A 612 SER A 613 VAL A 639 TYR A 645 TYR A 649 VAL A 692 HIS A 721	ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) None PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) None ILE  A 801 (-4.5A)	0.72A	2rguB-5yp3A: 34.6	2rguB-5yp3A: 8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RGU_B_356B902_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	8 / 11	GLU A 208 GLU A 209 TYR A 527 TRP A 612 SER A 613 VAL A 639 TYR A 645 TYR A 649	ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-4.7A) None PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A)	0.82A	2rguB-5yp3A: 34.6	2rguB-5yp3A: 8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RGU_B_356B902_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	5 / 11	GLU A 208 TYR A 527 SER A 613 VAL A 639 TYR A 645	ILE  A 801 (-3.4A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A)	1.23A	2rguB-5yp3A: 34.6	2rguB-5yp3A: 8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V32_D_BEZD1221_0 (PEROXIREDOXIN 6)	5c05	PUTATIVE GAMMA-TERPINENE SYNTHASE (Thymus vulgaris)	4 / 8	VAL A 448 THR A 454 PRO A 453 SER A 457	VAL  A 448 ( 0.5A) THR  A 454 ( 0.8A) PRO  A 453 ( 1.1A) SER  A 457 ( 0.0A)	0.95A	2v32C-5c05A: undetectable 2v32D-5c05A: undetectable	2v32C-5c05A: 17.32 2v32D-5c05A: 17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VOU_B_ACTB1391_0 (2,6-DIHYDROXYPYRIDIN E HYDROXYLASE)	1v0f	ENDO-ALPHA-SIALIDASE (Enterobacteria phage K1F)	3 / 3	PRO A 632 GLY A 705 TYR A 716	PRO  A 632 ( 1.1A) GLY  A 705 ( 0.0A) TYR  A 716 ( 1.3A)	0.65A	2vouB-1v0fA: undetectable	2vouB-1v0fA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VOU_C_ACTC1391_0 (2,6-DIHYDROXYPYRIDIN E HYDROXYLASE)	1v0f	ENDO-ALPHA-SIALIDASE (Enterobacteria phage K1F)	3 / 3	PRO A 632 GLY A 705 TYR A 716	PRO  A 632 ( 1.1A) GLY  A 705 ( 0.0A) TYR  A 716 ( 1.3A)	0.66A	2vouC-1v0fA: undetectable	2vouC-1v0fA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VOU_C_ACTC1391_0 (2,6-DIHYDROXYPYRIDIN E HYDROXYLASE)	4w65	GLYCOSYL HYDROLASE FAMILY PROTEIN (Mycolicibacteriu m fortuitum)	3 / 3	PRO A 238 GLY A 162 TYR A 244	PRO  A 238 ( 1.1A) GLY  A 162 ( 0.0A) TYR  A 244 ( 1.3A)	0.72A	2vouC-4w65A: undetectable	2vouC-4w65A: 23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VQ5_B_LDPB1197_1 (S-NORCOCLAURINE SYNTHASE)	3ab7	PUTATIVE UNCHARACTERIZED PROTEIN TTHA0350 (Thermus thermophilus)	4 / 7	LEU A  23 LEU A  27 LEU A 145 PRO A 176	LEU  A  23 ( 0.6A) LEU  A  27 ( 0.6A) LEU  A 145 ( 0.6A) PRO  A 176 ( 1.1A)	0.80A	2vq5B-3ab7A: undetectable	2vq5B-3ab7A: 21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W3M_A_FOLA1188_0 (DIHYDROFOLATE REDUCTASE)	5wpi	HSVA (Erwinia amylovora)	5 / 12	ILE A  38 ALA A 119 ILE A  51 PRO A  52 ASN A  55	ILE  A  38 ( 0.7A) ALA  A 119 ( 0.0A) ILE  A  51 ( 0.7A) PRO  A  52 ( 1.1A) ASN  A  55 ( 0.6A)	1.01A	2w3mA-5wpiA: undetectable	2w3mA-5wpiA: 18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WEK_B_DIFB1374_1 (ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2)	5nks	DIHYDROPYRIMIDINASE- RELATED PROTEIN 4 (Homo sapiens)	4 / 6	PRO A 220 ILE A 217 ASN A 347 LEU A 213	PRO  A 220 ( 1.1A) ILE  A 217 ( 0.7A) ASN  A 347 ( 0.6A) LEU  A 213 ( 0.5A)	1.37A	2wekB-5nksA: undetectable	2wekB-5nksA: 19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7K_A_SALA1303_1 (LYSR-TYPE REGULATORY PROTEIN)	3wd7	TYPE III POLYKETIDE SYNTHASES ACRIDONE SYNTHASE (Citrus x microcarpa)	4 / 7	PHE A 275 ILE A 309 PRO A 375 GLY A 374	PHE  A 275 ( 1.3A) ILE  A 309 ( 0.7A) PRO  A 375 ( 1.1A) GLY  A 374 ( 0.0A)	0.92A	2y7kA-3wd7A: undetectable	2y7kA-3wd7A: 20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YGP_A_PCFA1213_0 (WNT INHIBITORY FACTOR 1)	4ki5	COAGULATION FACTOR VIII (Homo sapiens)	5 / 12	ILE M2190 ILE M2185 VAL M2243 VAL M2240 PRO M2177	ILE  M2190 ( 0.7A) ILE  M2185 ( 0.7A) VAL  M2243 ( 0.6A) VAL  M2240 ( 0.6A) PRO  M2177 ( 1.1A)	0.94A	2ygpA-4ki5M: undetectable	2ygpA-4ki5M: 18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZGW_A_ADNA1301_1 (BIOTIN--[ACETYL-COA- CARBOXYLASE] LIGASE)	3sag	EXOSOME COMPONENT 10 (Homo sapiens)	4 / 7	ARG A 452 ALA A 270 PRO A 267 ALA A 268	ARG  A 452 ( 0.6A) ALA  A 270 ( 0.0A) PRO  A 267 ( 1.1A) ALA  A 268 ( 0.0A)	1.07A	2zgwA-3sagA: undetectable	2zgwA-3sagA: 19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZIF_A_SAMA298_0 (PUTATIVE MODIFICATION METHYLASE)	3ulk	KETOL-ACID REDUCTOISOMERASE (Escherichia coli)	5 / 12	ALA A 488 PRO A 154 PHE A 169 GLY A 199 THR A 198	ALA  A 488 ( 0.0A) PRO  A 154 (-1.1A) PHE  A 169 ( 1.3A) GLY  A 199 ( 0.0A) THR  A 198 ( 0.8A)	1.04A	2zifA-3ulkA: undetectable	2zifA-3ulkA: 20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZMB_A_PXBA692_1 (LACTOTRANSFERRIN)	5nks	DIHYDROPYRIMIDINASE- RELATED PROTEIN 4 (Homo sapiens)	3 / 3	PRO A 306 GLU A 221 TYR A 290	PRO  A 306 ( 1.1A) GLU  A 221 ( 0.6A) TYR  A 290 ( 1.3A)	0.79A	2zmbA-5nksA: undetectable	2zmbA-5nksA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZWE_B_DAHB98_1 (TYROSINASE MELC)	3ulk	KETOL-ACID REDUCTOISOMERASE (Escherichia coli)	5 / 11	ASN A 181 HIS A 178 VAL A 177 ASP A 182 PRO A 183	ASN  A 181 ( 0.6A) HIS  A 178 ( 1.0A) VAL  A 177 ( 0.6A) ASP  A 182 ( 0.6A) PRO  A 183 ( 1.1A)	0.96A	2zweA-3ulkA: undetectable 2zweB-3ulkA: undetectable	2zweA-3ulkA: 19.11 2zweB-3ulkA: 13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZWF_B_DAHB98_1 (TYROSINASE MELC)	3ulk	KETOL-ACID REDUCTOISOMERASE (Escherichia coli)	5 / 11	ASN A 181 HIS A 178 VAL A 177 ASP A 182 PRO A 183	ASN  A 181 ( 0.6A) HIS  A 178 ( 1.0A) VAL  A 177 ( 0.6A) ASP  A 182 ( 0.6A) PRO  A 183 ( 1.1A)	0.96A	2zwfA-3ulkA: undetectable 2zwfB-3ulkA: undetectable	2zwfA-3ulkA: 19.11 2zwfB-3ulkA: 13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZWG_B_DAHB98_1 (TYROSINASE MELC)	3ulk	KETOL-ACID REDUCTOISOMERASE (Escherichia coli)	5 / 11	ASN A 181 HIS A 178 VAL A 177 ASP A 182 PRO A 183	ASN  A 181 ( 0.6A) HIS  A 178 ( 1.0A) VAL  A 177 ( 0.6A) ASP  A 182 ( 0.6A) PRO  A 183 ( 1.1A)	0.97A	2zwgA-3ulkA: undetectable 2zwgB-3ulkA: undetectable	2zwgA-3ulkA: 19.11 2zwgB-3ulkA: 13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	316D_C_DVAC2_0 (8-FLUORO-ACTINOMYCIN D)	3gle	PILIN (Streptococcus pyogenes)	3 / 3	THR A  84 PRO A  48 THR A  50	THR  A  84 ( 0.8A) PRO  A  48 ( 1.1A) THR  A  50 ( 0.8A)	0.81A	316dC-3gleA: undetectable	316dC-3gleA: 9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	316D_C_DVAC2_0 (8-FLUORO-ACTINOMYCIN D)	5w0a	GLUCANASE (Trichoderma harzianum)	3 / 3	THR A   5 PRO A   8 THR A   7	THR  A   5 ( 0.8A) PRO  A   8 ( 1.1A) THR  A   7 ( 0.8A)	0.81A	316dC-5w0aA: undetectable	316dC-5w0aA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A25_A_SAMA279_0 (UNCHARACTERIZED PROTEIN PH0793)	4rdc	AMINO ACID/AMIDE ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN, HAAT FAMILY (Trichormus variabilis)	5 / 12	ASN A 201 ILE A 162 THR A 155 ASN A 139 PHE A 114	None None PRO  A 501 (-3.2A) None None	1.50A	3a25A-4rdcA: 2.6	3a25A-4rdcA: 20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A51_A_VDYA6178_1 (VITAMIN D HYDROXYLASE)	4mwt	LYSOSOMAL PROTECTIVE PROTEIN (Homo sapiens)	5 / 11	LEU A 387 ILE A 419 VAL A 176 PRO A 157 LEU A 174	LEU  A 387 ( 0.6A) ILE  A 419 ( 0.6A) VAL  A 176 ( 0.6A) PRO  A 157 ( 1.1A) LEU  A 174 ( 0.5A)	1.04A	3a51A-4mwtA: undetectable	3a51A-4mwtA: 23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A51_B_VDYB6178_1 (VITAMIN D HYDROXYLASE)	3r6y	ASPARTASE (Bacillus sp. YM55-1)	5 / 12	PRO A 330 LEU A 311 ASN A 293 VAL A 181 LEU A 197	PRO  A 330 ( 1.1A) LEU  A 311 ( 0.6A) ASN  A 293 ( 0.6A) VAL  A 181 ( 0.6A) LEU  A 197 ( 0.5A)	1.11A	3a51B-3r6yA: undetectable	3a51B-3r6yA: 23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A51_D_VDYD6178_1 (VITAMIN D HYDROXYLASE)	4mwt	LYSOSOMAL PROTECTIVE PROTEIN (Homo sapiens)	5 / 12	LEU A 387 ILE A 419 VAL A 176 PRO A 157 LEU A 174	LEU  A 387 ( 0.6A) ILE  A 419 ( 0.6A) VAL  A 176 ( 0.6A) PRO  A 157 ( 1.1A) LEU  A 174 ( 0.5A)	1.09A	3a51D-4mwtA: undetectable	3a51D-4mwtA: 23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABK_C_CHDC525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	5mc5	XAA-PRO DIPEPTIDASE (Homo sapiens)	4 / 7	HIS A 377 ASP A 453 THR A 410 HIS A 255	GLY  A 503 ( 3.9A) None MN  A 499 ( 4.0A) PRO  A 504 (-4.2A)	1.38A	3abkA-5mc5A: undetectable 3abkC-5mc5A: undetectable	3abkA-5mc5A: undetectable 3abkC-5mc5A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG2_A_CHDA525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	5mc5	XAA-PRO DIPEPTIDASE (Homo sapiens)	4 / 7	HIS A 377 ASP A 453 THR A 410 HIS A 255	GLY  A 503 ( 3.9A) None MN  A 499 ( 4.0A) PRO  A 504 (-4.2A)	1.39A	3ag2A-5mc5A: undetectable 3ag2C-5mc5A: 2.3	3ag2A-5mc5A: undetectable 3ag2C-5mc5A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG4_C_CHDC525_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	5mc5	XAA-PRO DIPEPTIDASE (Homo sapiens)	4 / 7	HIS A 377 ASP A 453 THR A 410 HIS A 255	GLY  A 503 ( 3.9A) None MN  A 499 ( 4.0A) PRO  A 504 (-4.2A)	1.40A	3ag4A-5mc5A: undetectable 3ag4C-5mc5A: undetectable	3ag4A-5mc5A: undetectable 3ag4C-5mc5A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AQI_A_CHDA2_0 (FERROCHELATASE)	2nvv	ACETYL-COA HYDROLASE/TRANSFERAS E FAMILY PROTEIN (Porphyromonas gingivalis)	4 / 6	MET A  57 ARG A  90 PRO A  32 GLY A  64	VAL  A  77 ( 3.9A) ARG  A  90 ( 0.6A) PRO  A  32 ( 1.1A) GLY  A  64 ( 0.0A)	1.34A	3aqiA-2nvvA: undetectable	3aqiA-2nvvA: 19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AQI_A_CHDA3_0 (FERROCHELATASE)	1ng0	COAT PROTEIN (Cocksfoot mottle virus)	3 / 3	PRO A  92 LEU A  95 ARG A  97	PRO  A  92 ( 1.1A) LEU  A  95 ( 0.6A) ARG  A  97 ( 0.6A)	0.92A	3aqiA-1ng0A: undetectable	3aqiA-1ng0A: 19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AQI_A_CHDA3_0 (FERROCHELATASE)	1wqa	PHOSPHO-SUGAR MUTASE (Pyrococcus horikoshii)	3 / 3	PRO A  20 LEU A  57 ARG A  48	PRO  A  20 ( 1.1A) LEU  A  57 ( 0.6A) ARG  A  48 ( 0.6A)	0.91A	3aqiA-1wqaA: 2.7	3aqiA-1wqaA: 20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJM_A_BJMA1_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	10 / 12	ARG A 106 GLU A 208 GLU A 209 TYR A 527 SER A 613 VAL A 639 TYR A 645 TYR A 649 ASN A 691 VAL A 692	ILE  A 801 (-4.2A) ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A) None	0.82A	3bjmA-5yp3A: 34.5	3bjmA-5yp3A: 8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJM_A_BJMA1_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	10 / 12	GLU A 208 GLU A 209 TYR A 527 SER A 613 VAL A 639 TYR A 645 TYR A 649 ASN A 691 VAL A 692 HIS A 721	ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A) None ILE  A 801 (-4.5A)	0.44A	3bjmA-5yp3A: 34.5	3bjmA-5yp3A: 8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJM_A_BJMA1_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	5 / 12	GLU A 208 TYR A 527 SER A 613 VAL A 639 TYR A 645	ILE  A 801 (-3.4A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A)	1.10A	3bjmA-5yp3A: 34.5	3bjmA-5yp3A: 8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJM_A_BJMA1_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	5 / 12	TYR A 617 TYR A 645 ASN A 691 VAL A 692 HIS A 721	None PRO  A 802 (-4.0A) ILE  A 801 (-3.1A) None ILE  A 801 (-4.5A)	1.08A	3bjmA-5yp3A: 34.5	3bjmA-5yp3A: 8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJM_B_BJMB2_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	9 / 12	ARG A 106 GLU A 208 GLU A 209 TYR A 527 VAL A 639 TYR A 645 TYR A 649 ASN A 691 VAL A 692	ILE  A 801 (-4.2A) ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-4.7A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A) None	0.83A	3bjmB-5yp3A: 34.2	3bjmB-5yp3A: 8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJM_B_BJMB2_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	10 / 12	GLU A 208 GLU A 209 TYR A 527 SER A 613 VAL A 639 TYR A 645 TYR A 649 ASN A 691 VAL A 692 HIS A 721	ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A) None ILE  A 801 (-4.5A)	0.43A	3bjmB-5yp3A: 34.2	3bjmB-5yp3A: 8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJM_B_BJMB2_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	5 / 12	GLU A 208 TYR A 527 SER A 613 VAL A 639 TYR A 645	ILE  A 801 (-3.4A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A)	1.13A	3bjmB-5yp3A: 34.2	3bjmB-5yp3A: 8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_G_SVRG506_3 (PHOSPHOLIPASE A2)	1fgv	H52 FV (LIGHT CHAIN) (Homo sapiens)	3 / 3	PRO L   8 PHE L  83 LYS L 103	PRO  L   8 ( 1.0A) PHE  L  83 ( 1.3A) LYS  L 103 ( 0.0A)	1.25A	3bjwG-1fgvL: 0.0	3bjwG-1fgvL: 20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D9L_A_ACTA501_0 (CTD-PEPTIDE RNA-BINDING PROTEIN 16)	3p9w	HUMAN VEGF (Homo sapiens)	4 / 5	ILE B  34 PRO B  52 TYR B  52 TYR B  33	ILE  B  34 ( 0.6A) PRO  B  52 ( 1.1A) TYR  B  52 ( 1.3A) TYR  B  33 ( 1.3A)	0.77A	3d9lA-3p9wB: undetectable 3d9lY-3p9wB: undetectable	3d9lA-3p9wB: 16.90 3d9lY-3p9wB: 8.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DGQ_A_EAAA211_1 (GLUTATHIONE S-TRANSFERASE P)	5mc5	XAA-PRO DIPEPTIDASE (Homo sapiens)	4 / 5	ARG A 450 ILE A 244 TYR A 241 THR A 242	PRO  A 504 (-3.7A) None GLY  A 503 ( 3.6A) None	1.31A	3dgqA-5mc5A: undetectable	3dgqA-5mc5A: 15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EBZ_B_017B201_1 (PROTEASE)	3e2s	PROLINE DEHYDROGENASE (Escherichia coli)	5 / 11	ASP A 285 GLY A 400 ILE A 399 ILE A 365 ILE A 326	PRO  A   1 (-4.0A) None None None None	1.12A	3ebzA-3e2sA: undetectable	3ebzA-3e2sA: 12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EEY_C_SAMC300_0 (PUTATIVE RRNA METHYLASE)	4rdc	AMINO ACID/AMIDE ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN, HAAT FAMILY (Trichormus variabilis)	5 / 12	GLY A 255 ASP A 202 ILE A 252 LEU A 282 THR A 215	None PRO  A 501 ( 4.8A) None None None	1.15A	3eeyC-4rdcA: 4.2	3eeyC-4rdcA: 21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EEY_E_SAME300_0 (PUTATIVE RRNA METHYLASE)	4rdc	AMINO ACID/AMIDE ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN, HAAT FAMILY (Trichormus variabilis)	5 / 12	GLY A 255 ASP A 202 ILE A 252 LEU A 282 THR A 215	None PRO  A 501 ( 4.8A) None None None	1.17A	3eeyE-4rdcA: undetectable	3eeyE-4rdcA: 21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3F8W_A_ADNA300_1 (PURINE-NUCLEOSIDE PHOSPHORYLASE)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	5 / 12	TYR A 527 ALA A 637 GLY A 616 ASN A 696 VAL A 692	PRO  A 802 (-4.7A) None None None None	1.17A	3f8wA-5yp3A: undetectable	3f8wA-5yp3A: 13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3F8W_C_ADNC302_1 (PURINE-NUCLEOSIDE PHOSPHORYLASE)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	5 / 12	TYR A 527 ALA A 637 GLY A 616 ASN A 696 VAL A 692	PRO  A 802 (-4.7A) None None None None	1.16A	3f8wC-5yp3A: undetectable	3f8wC-5yp3A: 13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FXR_A_ASCA3001_0 (LYSR TYPE REGULATOR OF TSAMBCD)	5ep8	PYRIMIDINE-NUCLEOSID E PHOSPHORYLASE (Bacillus subtilis)	4 / 8	ARG A 168 ALA A  42 ILE A  45 PRO A 178	ARG  A 168 ( 0.6A) ALA  A  42 ( 0.0A) ILE  A  45 ( 0.7A) PRO  A 178 ( 1.1A)	1.03A	3fxrA-5ep8A: undetectable	3fxrA-5ep8A: 22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_A_T22A800_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	9 / 12	ARG A 106 GLU A 208 GLU A 209 SER A 613 VAL A 639 TYR A 645 TYR A 649 ASN A 691 VAL A 692	ILE  A 801 (-4.2A) ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A) None	0.94A	3g0bA-5yp3A: 37.3	3g0bA-5yp3A: 8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_A_T22A800_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	9 / 12	ARG A 106 GLU A 208 GLU A 209 TYR A 527 SER A 613 VAL A 639 TYR A 645 TYR A 649 ASN A 691	ILE  A 801 (-4.2A) ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A)	0.98A	3g0bA-5yp3A: 37.3	3g0bA-5yp3A: 8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_A_T22A800_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	9 / 12	GLU A 208 GLU A 209 SER A 613 VAL A 639 TYR A 645 TYR A 649 ASN A 691 VAL A 692 HIS A 721	ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A) None ILE  A 801 (-4.5A)	0.59A	3g0bA-5yp3A: 37.3	3g0bA-5yp3A: 8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_A_T22A800_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	9 / 12	GLU A 208 GLU A 209 TYR A 527 SER A 613 VAL A 639 TYR A 645 TYR A 649 ASN A 691 HIS A 721	ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A) ILE  A 801 (-4.5A)	0.74A	3g0bA-5yp3A: 37.3	3g0bA-5yp3A: 8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_A_T22A800_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	5 / 12	GLU A 208 TYR A 527 SER A 613 VAL A 639 TYR A 645	ILE  A 801 (-3.4A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A)	1.32A	3g0bA-5yp3A: 37.3	3g0bA-5yp3A: 8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_A_T22A800_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	6 / 12	SER A 613 TYR A 617 TYR A 645 ASN A 691 VAL A 692 HIS A 721	PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) ILE  A 801 (-3.1A) None ILE  A 801 (-4.5A)	1.21A	3g0bA-5yp3A: 37.3	3g0bA-5yp3A: 8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_B_T22B800_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	9 / 12	ARG A 106 GLU A 208 GLU A 209 SER A 613 VAL A 639 TYR A 645 TYR A 649 ASN A 691 VAL A 692	ILE  A 801 (-4.2A) ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A) None	0.92A	3g0bB-5yp3A: 34.6	3g0bB-5yp3A: 8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_B_T22B800_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	9 / 12	ARG A 106 GLU A 208 GLU A 209 TYR A 527 SER A 613 VAL A 639 TYR A 645 TYR A 649 ASN A 691	ILE  A 801 (-4.2A) ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A)	0.96A	3g0bB-5yp3A: 34.6	3g0bB-5yp3A: 8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_B_T22B800_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	9 / 12	GLU A 208 GLU A 209 SER A 613 VAL A 639 TYR A 645 TYR A 649 ASN A 691 VAL A 692 HIS A 721	ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A) None ILE  A 801 (-4.5A)	0.57A	3g0bB-5yp3A: 34.6	3g0bB-5yp3A: 8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_B_T22B800_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	9 / 12	GLU A 208 GLU A 209 TYR A 527 SER A 613 VAL A 639 TYR A 645 TYR A 649 ASN A 691 HIS A 721	ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A) ILE  A 801 (-4.5A)	0.73A	3g0bB-5yp3A: 34.6	3g0bB-5yp3A: 8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_B_T22B800_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	5 / 12	GLU A 208 SER A 613 VAL A 639 TYR A 645 VAL A 692	ILE  A 801 (-3.4A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) None	1.33A	3g0bB-5yp3A: 34.6	3g0bB-5yp3A: 8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_B_T22B800_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	5 / 12	GLU A 208 TYR A 527 SER A 613 VAL A 639 TYR A 645	ILE  A 801 (-3.4A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A)	1.31A	3g0bB-5yp3A: 34.6	3g0bB-5yp3A: 8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_B_T22B800_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	5 / 12	SER A 613 TYR A 617 TYR A 645 ASN A 691 VAL A 692	PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) ILE  A 801 (-3.1A) None	1.25A	3g0bB-5yp3A: 34.6	3g0bB-5yp3A: 8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_C_T22C800_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	9 / 12	ARG A 106 GLU A 208 GLU A 209 TYR A 527 SER A 613 VAL A 639 TYR A 645 TYR A 649 ASN A 691	ILE  A 801 (-4.2A) ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A)	1.00A	3g0bC-5yp3A: 34.8	3g0bC-5yp3A: 8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_C_T22C800_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	8 / 12	ARG A 106 GLU A 208 GLU A 209 VAL A 639 TYR A 645 TYR A 649 ASN A 691 VAL A 692	ILE  A 801 (-4.2A) ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A) None	0.92A	3g0bC-5yp3A: 34.8	3g0bC-5yp3A: 8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_C_T22C800_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	8 / 12	GLU A 208 GLU A 209 SER A 613 VAL A 639 TYR A 645 TYR A 649 ASN A 691 HIS A 721	ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A) ILE  A 801 (-4.5A)	0.62A	3g0bC-5yp3A: 34.8	3g0bC-5yp3A: 8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_C_T22C800_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	8 / 12	GLU A 208 GLU A 209 VAL A 639 TYR A 645 TYR A 649 ASN A 691 VAL A 692 HIS A 721	ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A) None ILE  A 801 (-4.5A)	0.40A	3g0bC-5yp3A: 34.8	3g0bC-5yp3A: 8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_C_T22C800_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	5 / 12	GLU A 208 TYR A 527 SER A 613 VAL A 639 TYR A 645	ILE  A 801 (-3.4A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A)	1.32A	3g0bC-5yp3A: 34.8	3g0bC-5yp3A: 8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_D_T22D800_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	9 / 12	ARG A 106 GLU A 208 GLU A 209 SER A 613 VAL A 639 TYR A 645 TYR A 649 ASN A 691 VAL A 692	ILE  A 801 (-4.2A) ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A) None	0.94A	3g0bD-5yp3A: 34.7	3g0bD-5yp3A: 8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_D_T22D800_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	9 / 12	ARG A 106 GLU A 208 GLU A 209 TYR A 527 SER A 613 VAL A 639 TYR A 645 TYR A 649 ASN A 691	ILE  A 801 (-4.2A) ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A)	0.98A	3g0bD-5yp3A: 34.7	3g0bD-5yp3A: 8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_D_T22D800_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	9 / 12	GLU A 208 GLU A 209 SER A 613 VAL A 639 TYR A 645 TYR A 649 ASN A 691 VAL A 692 HIS A 721	ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A) None ILE  A 801 (-4.5A)	0.60A	3g0bD-5yp3A: 34.7	3g0bD-5yp3A: 8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_D_T22D800_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	9 / 12	GLU A 208 GLU A 209 TYR A 527 SER A 613 VAL A 639 TYR A 645 TYR A 649 ASN A 691 HIS A 721	ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A) ILE  A 801 (-4.5A)	0.75A	3g0bD-5yp3A: 34.7	3g0bD-5yp3A: 8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_D_T22D800_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	5 / 12	GLU A 208 SER A 613 VAL A 639 TYR A 645 VAL A 692	ILE  A 801 (-3.4A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) None	1.33A	3g0bD-5yp3A: 34.7	3g0bD-5yp3A: 8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_D_T22D800_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	5 / 12	GLU A 208 TYR A 527 SER A 613 VAL A 639 TYR A 645	ILE  A 801 (-3.4A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A)	1.29A	3g0bD-5yp3A: 34.7	3g0bD-5yp3A: 8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G0B_D_T22D800_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	6 / 12	SER A 613 TYR A 617 TYR A 645 ASN A 691 VAL A 692 HIS A 721	PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) ILE  A 801 (-3.1A) None ILE  A 801 (-4.5A)	1.24A	3g0bD-5yp3A: 34.7	3g0bD-5yp3A: 8.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3G4L_A_ROFA901_0 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D)	3sl5	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D (Homo sapiens)	10 / 12	TYR A 159 HIS A 160 ASN A 321 PRO A 322 TYR A 329 TRP A 332 THR A 333 ILE A 336 MET A 357 SER A 368	TYR  A 159 (-1.3A) HIS  A 160 ( 1.0A) ASN  A 321 (-0.6A) PRO  A 322 (-1.1A) TYR  A 329 (-1.3A) TRP  A 332 ( 0.5A) THR  A 333 ( 0.8A) ILE  A 336 ( 0.4A) MET  A 357 (-0.0A) SER  A 368 (-0.0A)	0.52A	3g4lA-3sl5A: 53.4	3g4lA-3sl5A: 98.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3G4L_A_ROFA901_0 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D)	3sl5	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D (Homo sapiens)	11 / 12	TYR A 159 HIS A 160 MET A 273 ASN A 321 PRO A 322 TYR A 329 TRP A 332 THR A 333 ILE A 336 SER A 368 PHE A 372	TYR  A 159 (-1.3A) HIS  A 160 ( 1.0A) MET  A 273 (-0.0A) ASN  A 321 (-0.6A) PRO  A 322 (-1.1A) TYR  A 329 (-1.3A) TRP  A 332 ( 0.5A) THR  A 333 ( 0.8A) ILE  A 336 ( 0.4A) SER  A 368 (-0.0A) PHE  A 372 (-1.3A)	0.44A	3g4lA-3sl5A: 53.4	3g4lA-3sl5A: 98.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3G4L_B_ROFB902_0 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D)	3sl5	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D (Homo sapiens)	12 / 12	TYR A 159 HIS A 160 MET A 273 ASP A 318 LEU A 319 PRO A 322 TRP A 332 THR A 333 ILE A 336 MET A 337 MET A 357 PHE A 372	TYR  A 159 (-1.3A) HIS  A 160 ( 1.0A) MET  A 273 (-0.0A) ASP  A 318 (-0.5A) LEU  A 319 ( 0.6A) PRO  A 322 (-1.1A) TRP  A 332 ( 0.5A) THR  A 333 ( 0.8A) ILE  A 336 ( 0.4A) MET  A 337 ( 0.0A) MET  A 357 (-0.0A) PHE  A 372 (-1.3A)	0.53A	3g4lB-3sl5A: 52.8	3g4lB-3sl5A: 98.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3G4L_C_ROFC903_0 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D)	3sl5	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D (Homo sapiens)	12 / 12	TYR A 159 HIS A 160 MET A 273 ASP A 318 LEU A 319 ASN A 321 PRO A 322 TYR A 329 TRP A 332 THR A 333 ILE A 336 MET A 357	TYR  A 159 (-1.3A) HIS  A 160 ( 1.0A) MET  A 273 (-0.0A) ASP  A 318 (-0.5A) LEU  A 319 ( 0.6A) ASN  A 321 (-0.6A) PRO  A 322 (-1.1A) TYR  A 329 (-1.3A) TRP  A 332 ( 0.5A) THR  A 333 ( 0.8A) ILE  A 336 ( 0.4A) MET  A 357 (-0.0A)	0.46A	3g4lC-3sl5A: 53.0	3g4lC-3sl5A: 98.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3G4L_D_ROFD904_0 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D)	3sl5	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D (Homo sapiens)	12 / 12	TYR A 159 HIS A 160 MET A 273 ASP A 318 LEU A 319 PRO A 322 TRP A 332 THR A 333 ILE A 336 MET A 337 SER A 368 GLN A 369	TYR  A 159 (-1.3A) HIS  A 160 ( 1.0A) MET  A 273 (-0.0A) ASP  A 318 (-0.5A) LEU  A 319 ( 0.6A) PRO  A 322 (-1.1A) TRP  A 332 ( 0.5A) THR  A 333 ( 0.8A) ILE  A 336 ( 0.4A) MET  A 337 ( 0.0A) SER  A 368 (-0.0A) GLN  A 369 (-0.6A)	0.33A	3g4lD-3sl5A: 52.9	3g4lD-3sl5A: 98.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3H52_D_486D2_1 (GLUCOCORTICOID RECEPTOR)	2nvv	ACETYL-COA HYDROLASE/TRANSFERAS E FAMILY PROTEIN (Porphyromonas gingivalis)	5 / 12	GLY A 134 GLN A 200 VAL A 201 MET A 168 LEU A 137	GLY  A 134 ( 0.0A) GLN  A 200 ( 0.6A) VAL  A 201 ( 0.6A) PRO  A 197 ( 3.9A) LEU  A 137 ( 0.6A)	1.48A	3h52D-2nvvA: undetectable	3h52D-2nvvA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HCN_A_CHDA3_0 (FERROCHELATASE, MITOCHONDRIAL)	5ec3	4-HYDROXYPHENYLPYRUV ATE DIOXYGENASE (Homo sapiens)	4 / 7	LEU A 367 PRO A 239 SER A 226 GLY A 358	LEU  A 367 ( 0.6A) PRO  A 239 ( 1.1A) SER  A 226 ( 0.0A) GLY  A 358 ( 0.0A)	1.07A	3hcnA-5ec3A: undetectable	3hcnA-5ec3A: 22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HCN_B_CHDB1_0 (FERROCHELATASE, MITOCHONDRIAL)	5xlu	GAMMA GLUTAMYL TRANSPEPTIDASE (Bacillus licheniformis)	5 / 9	LEU A 150 PRO A 168 SER A 169 VAL A  59 GLY A  56	LEU  A 150 ( 0.6A) PRO  A 168 ( 1.1A) SER  A 169 ( 0.0A) VAL  A  59 ( 0.6A) GLY  A  56 ( 0.0A)	1.38A	3hcnB-5xluA: undetectable	3hcnB-5xluA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HCO_B_CHDB1_0 (FERROCHELATASE, MITOCHONDRIAL)	3r9r	PHOSPHORIBOSYLAMINOI MIDAZOLE-SUCCINOCARB OXAMIDE SYNTHASE (Mycobacteroides abscessus)	4 / 4	LEU A 125 PRO A 126 LEU A 129 ARG A 134	LEU  A 125 ( 0.6A) PRO  A 126 ( 1.1A) LEU  A 129 ( 0.6A) ARG  A 134 ( 0.6A)	1.18A	3hcoB-3r9rA: undetectable	3hcoB-3r9rA: 21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HCO_B_CHDB1_0 (FERROCHELATASE, MITOCHONDRIAL)	5xlu	GAMMA GLUTAMYL TRANSPEPTIDASE (Bacillus licheniformis)	4 / 4	LEU A 345 PRO A 344 LEU A 348 ARG A 331	LEU  A 345 ( 0.5A) PRO  A 344 ( 1.1A) LEU  A 348 ( 0.5A) ARG  A 331 ( 0.6A)	1.39A	3hcoB-5xluA: undetectable	3hcoB-5xluA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HEC_A_STIA1_2 (MITOGEN-ACTIVATED PROTEIN KINASE 14)	3e2s	PROLINE DEHYDROGENASE (Escherichia coli)	4 / 4	LEU A 393 MET A 346 ILE A 430 ASP A 370	None None None PRO  A   1 ( 3.8A)	1.14A	3hecA-3e2sA: undetectable	3hecA-3e2sA: 21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HZN_G_ACTG225_0 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	3sag	EXOSOME COMPONENT 10 (Homo sapiens)	3 / 3	PRO A 580 LEU A 581 GLN A 505	PRO  A 580 ( 1.1A) LEU  A 581 ( 0.6A) GLN  A 505 ( 0.6A)	0.69A	3hznG-3sagA: undetectable 3hznH-3sagA: undetectable	3hznG-3sagA: 17.87 3hznH-3sagA: 17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IB0_A_DIFA701_1 (LACTOTRANSFERRIN)	4kqn	D-HYDANTOINASE (Bacillus sp. AR9)	4 / 4	PRO A 398 TYR A  49 GLY A  47 THR A  46	PRO  A 398 ( 1.1A) TYR  A  49 ( 1.3A) GLY  A  47 ( 0.0A) THR  A  46 ( 0.8A)	1.41A	3ib0A-4kqnA: undetectable	3ib0A-4kqnA: 20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IB1_A_IMNA701_1 (LACTOTRANSFERRIN)	1wsv	AMINOMETHYLTRANSFERA SE (Homo sapiens)	4 / 4	PRO A 344 THR A 346 GLY A 317 THR A 318	PRO  A 344 ( 1.1A) THR  A 346 ( 0.8A) GLY  A 317 ( 0.0A) THR  A 318 ( 0.8A)	1.14A	3ib1A-1wsvA: undetectable	3ib1A-1wsvA: 20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JB2_A_SAMA1101_0 (STRUCTURAL PROTEIN VP3)	2qc5	STREPTOGRAMIN B LACTONASE (Staphylococcus cohnii)	5 / 12	ASN A 138 SER A 141 GLU A 175 PRO A 137 GLU A 217	ASN  A 138 ( 0.6A) SER  A 141 ( 0.0A) GLU  A 175 ( 0.6A) PRO  A 137 ( 1.1A) GLU  A 217 ( 0.6A)	1.46A	3jb2A-2qc5A: undetectable	3jb2A-2qc5A: 14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KPB_A_SAMA1000_0 (UNCHARACTERIZED PROTEIN MJ0100)	2vbf	BRANCHED-CHAIN ALPHA-KETOACID DECARBOXYLASE (Lactococcus lactis)	5 / 12	THR A 237 VAL A 210 ILE A 276 SER A 272 PRO A 208	THR  A 237 ( 0.8A) VAL  A 210 ( 0.6A) ILE  A 276 ( 0.6A) SER  A 272 ( 0.0A) PRO  A 208 ( 1.1A)	1.24A	3kpbA-2vbfA: undetectable	3kpbA-2vbfA: 12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MEC_A_65BA561_0 (P66 REVERSE TRANSCRIPTASE)	1wsv	AMINOMETHYLTRANSFERA SE (Homo sapiens)	5 / 12	LEU A 348 VAL A 319 VAL A 293 GLY A 335 PRO A 307	LEU  A 348 ( 0.6A) VAL  A 319 ( 0.6A) VAL  A 293 ( 0.6A) GLY  A 335 ( 0.0A) PRO  A 307 ( 1.1A)	1.22A	3mecA-1wsvA: 2.1	3mecA-1wsvA: 20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MJR_D_AC2D601_1 (DEOXYCYTIDINE KINASE)	4p7w	L-PROLINE CIS-4-HYDROXYLASE (Mesorhizobium japonicum)	4 / 8	GLU A 111 ARG A 272 ASP A  34 PHE A  35	None None None PRO  A 303 (-3.5A)	1.09A	3mjrD-4p7wA: undetectable	3mjrD-4p7wA: 22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ONN_A_ACTA270_0 (PROTEIN SSM1)	4g9k	ROTENONE-INSENSITIVE NADH-UBIQUINONE OXIDOREDUCTASE (Saccharomyces cerevisiae)	4 / 5	LEU A 195 SER A 201 LEU A  94 PRO A  95	LEU  A 195 (-0.6A) SER  A 201 ( 0.0A) LEU  A  94 ( 0.6A) PRO  A  95 ( 1.1A)	1.23A	3onnA-4g9kA: undetectable	3onnA-4g9kA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3Q07_A_WPPA300_2 (BETA-LACTAMASE)	3gnr	OS03G0212800 PROTEIN (Oryza sativa)	4 / 5	TYR A 321 PRO A 371 THR A 425 THR A 393	TYR  A 321 (-1.3A) PRO  A 371 ( 1.1A) THR  A 425 ( 0.8A) THR  A 393 ( 0.8A)	1.38A	3q07A-3gnrA: undetectable	3q07A-3gnrA: 22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3Q07_B_WPPB400_2 (BETA-LACTAMASE)	3gnr	OS03G0212800 PROTEIN (Oryza sativa)	4 / 5	TYR A 321 PRO A 371 THR A 425 THR A 393	TYR  A 321 (-1.3A) PRO  A 371 ( 1.1A) THR  A 425 ( 0.8A) THR  A 393 ( 0.8A)	1.34A	3q07B-3gnrA: undetectable	3q07B-3gnrA: 22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3S_E_9PLE1_1 (CYTOCHROME P450 2A13)	4rdc	AMINO ACID/AMIDE ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN, HAAT FAMILY (Trichormus variabilis)	4 / 8	ALA A 135 ASN A 154 PHE A 204 ALA A 156	None None PRO  A 501 (-3.4A) PRO  A 501 ( 4.9A)	1.03A	3t3sE-4rdcA: undetectable	3t3sE-4rdcA: 21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TGV_C_BEZC1_0 (HEME-BINDING PROTEIN HUTZ)	5nqf	APICAL MEMBRANE ANTIGEN 1 (Plasmodium falciparum)	4 / 5	TYR A 117 PHE A 312 PRO A 416 LEU A 419	TYR  A 117 ( 1.3A) PHE  A 312 ( 1.3A) PRO  A 416 ( 1.1A) LEU  A 419 ( 0.5A)	1.48A	3tgvC-5nqfA: undetectable	3tgvC-5nqfA: 16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TGV_D_BEZD1_0 (HEME-BINDING PROTEIN HUTZ)	5nqf	APICAL MEMBRANE ANTIGEN 1 (Plasmodium falciparum)	4 / 6	TYR A 117 PHE A 312 PRO A 416 LEU A 419	TYR  A 117 ( 1.3A) PHE  A 312 ( 1.3A) PRO  A 416 ( 1.1A) LEU  A 419 ( 0.5A)	1.34A	3tgvD-5nqfA: undetectable	3tgvD-5nqfA: 16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TKG_C_ROCC901_3 (PROTEASE)	2nvv	ACETYL-COA HYDROLASE/TRANSFERAS E FAMILY PROTEIN (Porphyromonas gingivalis)	3 / 3	ASP A 413 THR A 393 PRO A 394	ASP  A 413 (-0.5A) THR  A 393 ( 0.8A) PRO  A 394 ( 1.1A)	0.66A	3tkgD-2nvvA: undetectable	3tkgD-2nvvA: 13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TKG_C_ROCC901_3 (PROTEASE)	5c6d	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 (Homo sapiens)	3 / 3	ASP A 722 THR A 707 PRO A 708	ASP  A 722 ( 0.6A) THR  A 707 ( 0.8A) PRO  A 708 ( 1.1A)	0.67A	3tkgD-5c6dA: undetectable	3tkgD-5c6dA: 16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TPX_E_ACTE204_0 (E3 UBIQUITIN-PROTEIN LIGASE MDM2)	4mwt	LYSOSOMAL PROTECTIVE PROTEIN (Homo sapiens)	3 / 3	LYS A 435 PRO A 436 LEU A 437	LYS  A 435 ( 0.0A) PRO  A 436 ( 1.1A) LEU  A 437 ( 0.6A)	0.68A	3tpxE-4mwtA: undetectable	3tpxE-4mwtA: 11.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TVX_A_PNXA902_1 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4A)	3sl5	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D (Homo sapiens)	9 / 9	TYR A 159 LEU A 319 ASN A 321 PRO A 322 THR A 333 ILE A 336 MET A 357 GLN A 369 PHE A 372	TYR  A 159 (-1.3A) LEU  A 319 ( 0.6A) ASN  A 321 (-0.6A) PRO  A 322 (-1.1A) THR  A 333 ( 0.8A) ILE  A 336 ( 0.4A) MET  A 357 (-0.0A) GLN  A 369 (-0.6A) PHE  A 372 (-1.3A)	0.46A	3tvxA-3sl5A: 51.5	3tvxA-3sl5A: 85.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UCB_B_017B202_1 (PROTEASE)	3ghg	FIBRINOGEN GAMMA CHAIN (Homo sapiens)	4 / 7	LYS C 273 ARG C 275 GLY C 268 PRO C 269	LYS  C 273 ( 0.0A) ARG  C 275 ( 0.6A) GLY  C 268 ( 0.0A) PRO  C 269 ( 1.1A)	1.32A	3ucbB-3ghgC: undetectable	3ucbB-3ghgC: 12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFN_A_ROCA402_1 (HIV-1 PROTEASE)	5c05	PUTATIVE GAMMA-TERPINENE SYNTHASE (Thymus vulgaris)	4 / 5	ARG A 490 LEU A 443 PRO A 437 ASP A 494	ARG  A 490 ( 0.6A) LEU  A 443 ( 0.6A) PRO  A 437 ( 1.1A) ASP  A 494 ( 0.6A)	1.07A	3ufnA-5c05A: undetectable 3ufnB-5c05A: undetectable	3ufnA-5c05A: 10.81 3ufnB-5c05A: 10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UGR_A_IMNA2001_2 (ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	4 / 7	TYR A 492 GLN A 533 TYR A 527 TYR A 610	None None PRO  A 802 (-4.7A) None	0.88A	3ugrA-5yp3A: undetectable	3ugrA-5yp3A: 14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V4T_C_ACTC502_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	5ep8	PYRIMIDINE-NUCLEOSID E PHOSPHORYLASE (Bacillus subtilis)	3 / 3	PRO A 105 ASP A 103 GLU A  75	PRO  A 105 ( 1.1A) ASP  A 103 ( 0.6A) GLU  A  75 ( 0.6A)	0.83A	3v4tC-5ep8A: undetectable	3v4tC-5ep8A: 26.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V8V_A_SAMA801_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L)	5xlu	GAMMA GLUTAMYL TRANSPEPTIDASE (Bacillus licheniformis)	5 / 12	ILE A  87 THR A 224 ASN A  78 PRO A  82 LEU A 183	ILE  A  87 ( 0.6A) THR  A 224 ( 0.8A) ASN  A  78 ( 0.6A) PRO  A  82 ( 1.1A) LEU  A 183 ( 0.6A)	1.20A	3v8vA-5xluA: undetectable	3v8vA-5xluA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VLN_A_ASCA904_0 (GLUTATHIONE S-TRANSFERASE OMEGA-1)	3i4k	MUCONATE LACTONIZING ENZYME (Corynebacterium glutamicum)	4 / 6	PHE A 331 LEU A 330 PRO A 333 GLU A 306	PHE  A 331 ( 1.3A) LEU  A 330 ( 0.6A) PRO  A 333 ( 1.1A) GLU  A 306 ( 0.5A)	1.39A	3vlnA-3i4kA: undetectable	3vlnA-3i4kA: 20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VLN_A_ASCA904_0 (GLUTATHIONE S-TRANSFERASE OMEGA-1)	6ezy	- (-)	4 / 6	ARG A  15 PRO A  54 GLU A  65 SER A  66	ARG  A  15 ( 0.6A) PRO  A  54 ( 1.1A) GLU  A  65 ( 0.6A) SER  A  66 ( 0.0A)	0.95A	3vlnA-6ezyA: 20.5	3vlnA-6ezyA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W1W_B_CHDB503_0 (FERROCHELATASE, MITOCHONDRIAL)	4flx	DNA POLYMERASE 1 (Pyrococcus abyssi)	3 / 3	LEU A 571 PRO A 572 LEU A 575	LEU  A 571 ( 0.5A) PRO  A 572 ( 1.1A) LEU  A 575 ( 0.6A)	0.46A	3w1wB-4flxA: undetectable	3w1wB-4flxA: 19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W2T_A_LF7A801_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	10 / 12	ARG A 106 GLU A 208 GLU A 209 TYR A 527 SER A 613 VAL A 639 TYR A 645 TYR A 649 ASN A 691 VAL A 692	ILE  A 801 (-4.2A) ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A) None	0.80A	3w2tA-5yp3A: 34.3	3w2tA-5yp3A: 8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W2T_A_LF7A801_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	10 / 12	GLU A 208 GLU A 209 TYR A 527 SER A 613 VAL A 639 TYR A 645 TYR A 649 ASN A 691 VAL A 692 HIS A 721	ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A) None ILE  A 801 (-4.5A)	0.33A	3w2tA-5yp3A: 34.3	3w2tA-5yp3A: 8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W2T_A_LF7A801_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	5 / 12	GLU A 208 TYR A 527 SER A 613 VAL A 639 TYR A 645	ILE  A 801 (-3.4A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A)	1.03A	3w2tA-5yp3A: 34.3	3w2tA-5yp3A: 8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W2T_A_LF7A801_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	5 / 12	TYR A 617 TYR A 645 ASN A 691 VAL A 692 HIS A 721	None PRO  A 802 (-4.0A) ILE  A 801 (-3.1A) None ILE  A 801 (-4.5A)	1.14A	3w2tA-5yp3A: 34.3	3w2tA-5yp3A: 8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W2T_B_LF7B801_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	10 / 12	ARG A 106 GLU A 208 GLU A 209 TYR A 527 SER A 613 VAL A 639 TYR A 645 TYR A 649 ASN A 691 VAL A 692	ILE  A 801 (-4.2A) ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A) None	0.79A	3w2tB-5yp3A: 34.6	3w2tB-5yp3A: 8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W2T_B_LF7B801_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	10 / 12	GLU A 208 GLU A 209 TYR A 527 SER A 613 VAL A 639 TYR A 645 TYR A 649 ASN A 691 VAL A 692 HIS A 721	ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A) None ILE  A 801 (-4.5A)	0.32A	3w2tB-5yp3A: 34.6	3w2tB-5yp3A: 8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W2T_B_LF7B801_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	5 / 12	GLU A 208 TYR A 527 SER A 613 VAL A 639 TYR A 645	ILE  A 801 (-3.4A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A)	1.06A	3w2tB-5yp3A: 34.6	3w2tB-5yp3A: 8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W2T_B_LF7B801_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	5 / 12	TYR A 617 TYR A 645 ASN A 691 VAL A 692 HIS A 721	None PRO  A 802 (-4.0A) ILE  A 801 (-3.1A) None ILE  A 801 (-4.5A)	1.13A	3w2tB-5yp3A: 34.6	3w2tB-5yp3A: 8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AWU_A_4CHA502_0 (OXIDOREDUCTASE, FMN-BINDING)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	4 / 7	THR A1121 TYR A1127 LEU A1244 PHE A1097	PRO  A1602 (-3.5A) None None None	1.29A	4awuA-5vadA: undetectable	4awuA-5vadA: 20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BLV_A_SAMA1281_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J)	5ve2	ENOYL-COA HYDRATASE (Pseudoalteromona s atlantica)	5 / 12	LEU A 144 GLY A 105 LEU A 156 GLY A 160 PRO A 136	LEU  A 144 ( 0.6A) GLY  A 105 ( 0.0A) LEU  A 156 ( 0.5A) GLY  A 160 ( 0.0A) PRO  A 136 ( 1.1A)	1.03A	4blvA-5ve2A: undetectable	4blvA-5ve2A: 18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D33_A_ACTA860_0 (NITRIC OXIDE SYNTHASE, ENDOTHELIAL)	4rdc	AMINO ACID/AMIDE ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN, HAAT FAMILY (Trichormus variabilis)	4 / 5	GLY A 158 ILE A 159 VAL A 173 SER A 132	None None None PRO  A 501 (-2.6A)	1.26A	4d33A-4rdcA: undetectable	4d33A-4rdcA: 20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D33_B_ACTB860_0 (NITRIC OXIDE SYNTHASE, ENDOTHELIAL)	4rdc	AMINO ACID/AMIDE ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN, HAAT FAMILY (Trichormus variabilis)	4 / 5	GLY A 158 ILE A 159 VAL A 173 SER A 132	None None None PRO  A 501 (-2.6A)	1.23A	4d33B-4rdcA: undetectable	4d33B-4rdcA: 20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DM8_A_REAA501_1 (RETINOIC ACID RECEPTOR BETA)	5mc5	XAA-PRO DIPEPTIDASE (Homo sapiens)	5 / 11	LEU A 274 ILE A 244 SER A 286 LEU A 254 ILE A 451	None None None PRO  A 504 (-4.5A) None	1.20A	4dm8A-5mc5A: undetectable	4dm8A-5mc5A: 15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DM8_A_REAA501_1 (RETINOIC ACID RECEPTOR BETA)	5wze	AMINOPEPTIDASE P (Pseudomonas aeruginosa)	5 / 11	LEU A 258 ILE A 232 SER A 270 LEU A 242 ILE A 407	None None None PRO  A 504 ( 4.4A) None	1.07A	4dm8A-5wzeA: undetectable	4dm8A-5wzeA: 15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DUB_B_LDPB501_1 (CYTOCHROME P450 BM3 VARIANT 9D7)	3r9r	PHOSPHORIBOSYLAMINOI MIDAZOLE-SUCCINOCARB OXAMIDE SYNTHASE (Mycobacteroides abscessus)	4 / 6	PHE A 289 ALA A  55 GLY A 294 PRO A 295	PHE  A 289 ( 1.3A) ALA  A  55 ( 0.0A) GLY  A 294 ( 0.0A) PRO  A 295 ( 1.1A)	0.87A	4dubB-3r9rA: undetectable	4dubB-3r9rA: 21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DXU_A_ACAA711_1 (LACTOTRANSFERRIN)	3ulk	KETOL-ACID REDUCTOISOMERASE (Escherichia coli)	4 / 6	GLY A 200 VAL A 205 PRO A 172 TYR A 388	GLY  A 200 ( 0.0A) VAL  A 205 ( 0.6A) PRO  A 172 ( 1.1A) TYR  A 388 ( 1.3A)	0.84A	4dxuA-3ulkA: undetectable	4dxuA-3ulkA: 20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E1V_A_URFA1301_1 (URIDINE PHOSPHORYLASE)	5ep8	PYRIMIDINE-NUCLEOSID E PHOSPHORYLASE (Bacillus subtilis)	4 / 8	GLY A 355 ILE A 247 VAL A  87 PRO A 242	GLY  A 355 ( 0.0A) ILE  A 247 ( 0.6A) VAL  A  87 ( 0.6A) PRO  A 242 ( 1.1A)	0.93A	4e1vA-5ep8A: 3.2	4e1vA-5ep8A: 20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E1V_B_URFB1301_1 (URIDINE PHOSPHORYLASE)	5ep8	PYRIMIDINE-NUCLEOSID E PHOSPHORYLASE (Bacillus subtilis)	4 / 7	GLY A 355 ILE A 247 VAL A  87 PRO A 242	GLY  A 355 ( 0.0A) ILE  A 247 ( 0.6A) VAL  A  87 ( 0.6A) PRO  A 242 ( 1.1A)	0.92A	4e1vB-5ep8A: 3.0	4e1vB-5ep8A: 20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E1V_C_URFC1301_1 (URIDINE PHOSPHORYLASE)	5ep8	PYRIMIDINE-NUCLEOSID E PHOSPHORYLASE (Bacillus subtilis)	4 / 8	GLY A 355 ILE A 247 VAL A  87 PRO A 242	GLY  A 355 ( 0.0A) ILE  A 247 ( 0.6A) VAL  A  87 ( 0.6A) PRO  A 242 ( 1.1A)	0.92A	4e1vC-5ep8A: 3.1	4e1vC-5ep8A: 20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E1V_D_URFD1301_1 (URIDINE PHOSPHORYLASE)	5ep8	PYRIMIDINE-NUCLEOSID E PHOSPHORYLASE (Bacillus subtilis)	4 / 8	GLY A 355 ILE A 247 VAL A  87 PRO A 242	GLY  A 355 ( 0.0A) ILE  A 247 ( 0.6A) VAL  A  87 ( 0.6A) PRO  A 242 ( 1.1A)	0.93A	4e1vD-5ep8A: 3.1	4e1vD-5ep8A: 20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E1V_E_URFE1301_1 (URIDINE PHOSPHORYLASE)	5ep8	PYRIMIDINE-NUCLEOSID E PHOSPHORYLASE (Bacillus subtilis)	4 / 8	GLY A 355 ILE A 247 VAL A  87 PRO A 242	GLY  A 355 ( 0.0A) ILE  A 247 ( 0.6A) VAL  A  87 ( 0.6A) PRO  A 242 ( 1.1A)	0.96A	4e1vE-5ep8A: 3.2	4e1vE-5ep8A: 20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E1V_G_URFG1301_1 (URIDINE PHOSPHORYLASE)	5ep8	PYRIMIDINE-NUCLEOSID E PHOSPHORYLASE (Bacillus subtilis)	4 / 8	GLY A 355 ILE A 247 VAL A  87 PRO A 242	GLY  A 355 ( 0.0A) ILE  A 247 ( 0.6A) VAL  A  87 ( 0.6A) PRO  A 242 ( 1.1A)	0.94A	4e1vG-5ep8A: 3.0	4e1vG-5ep8A: 20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E1V_H_URFH1301_1 (URIDINE PHOSPHORYLASE)	5ep8	PYRIMIDINE-NUCLEOSID E PHOSPHORYLASE (Bacillus subtilis)	4 / 8	GLY A 355 ILE A 247 VAL A  87 PRO A 242	GLY  A 355 ( 0.0A) ILE  A 247 ( 0.6A) VAL  A  87 ( 0.6A) PRO  A 242 ( 1.1A)	0.90A	4e1vH-5ep8A: 3.3	4e1vH-5ep8A: 20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EY7_B_E20B605_1 (ACETYLCHOLINESTERASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	5 / 11	TRP A1169 TYR A1193 GLU A1123 SER A1272 HIS A1173	None None PRO  A1602 (-2.8A) PRO  A1602 (-3.3A) PRO  A1602 ( 4.5A)	1.48A	4ey7B-5vadA: undetectable	4ey7B-5vadA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F4D_B_CHDB504_0 (FERROCHELATASE, MITOCHONDRIAL)	3gnr	OS03G0212800 PROTEIN (Oryza sativa)	4 / 4	LEU A 135 PRO A 136 LEU A 139 ILE A 151	LEU  A 135 ( 0.6A) PRO  A 136 ( 1.1A) LEU  A 139 ( 0.6A) ILE  A 151 ( 0.4A)	0.86A	4f4dB-3gnrA: undetectable	4f4dB-3gnrA: 21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F4D_B_CHDB504_0 (FERROCHELATASE, MITOCHONDRIAL)	5wo6	TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 6 (Rattus norvegicus)	4 / 4	LEU A 167 PRO A 166 LEU A 182 ILE A 183	LEU  A 167 ( 0.6A) PRO  A 166 ( 1.1A) LEU  A 182 ( 0.6A) ILE  A 183 ( 0.7A)	0.98A	4f4dB-5wo6A: undetectable	4f4dB-5wo6A: 19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FFW_A_715A801_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	9 / 12	ARG A 106 GLU A 208 GLU A 209 TYR A 527 SER A 613 VAL A 639 TYR A 645 ASN A 691 VAL A 692	ILE  A 801 (-4.2A) ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) ILE  A 801 (-3.1A) None	0.86A	4ffwA-5yp3A: 35.5	4ffwA-5yp3A: 7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FFW_A_715A801_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	9 / 12	GLU A 208 GLU A 209 TYR A 527 SER A 613 VAL A 639 TYR A 645 ASN A 691 VAL A 692 HIS A 721	ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) ILE  A 801 (-3.1A) None ILE  A 801 (-4.5A)	0.47A	4ffwA-5yp3A: 35.5	4ffwA-5yp3A: 7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FFW_A_715A801_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	5 / 12	GLU A 208 TYR A 527 SER A 613 VAL A 639 TYR A 645	ILE  A 801 (-3.4A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A)	1.13A	4ffwA-5yp3A: 35.5	4ffwA-5yp3A: 7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FFW_B_715B801_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	10 / 12	ARG A 106 GLU A 208 GLU A 209 TYR A 527 SER A 613 VAL A 639 TYR A 645 TYR A 649 VAL A 692 HIS A 721	ILE  A 801 (-4.2A) ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) None ILE  A 801 (-4.5A)	0.66A	4ffwB-5yp3A: 36.5	4ffwB-5yp3A: 7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FFW_B_715B801_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	5 / 12	GLU A 208 TYR A 527 SER A 613 VAL A 639 TYR A 645	ILE  A 801 (-3.4A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A)	1.06A	4ffwB-5yp3A: 36.5	4ffwB-5yp3A: 7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGK_A_0TXA302_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5gpr	CHITINASE (Ostrinia furnacalis)	4 / 6	PHE A 286 ILE A 185 PRO A 186 PHE A 274	PHE  A 286 ( 1.3A) ILE  A 185 ( 0.7A) PRO  A 186 ( 1.1A) PHE  A 274 ( 1.3A)	1.11A	4fgkA-5gprA: undetectable	4fgkA-5gprA: 17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FIM_A_CELA711_1 (LACTOTRANSFERRIN)	4kqn	D-HYDANTOINASE (Bacillus sp. AR9)	5 / 9	GLY A 425 VAL A 400 PRO A 398 TYR A  49 GLY A  47	GLY  A 425 ( 0.0A) VAL  A 400 ( 0.6A) PRO  A 398 ( 1.1A) TYR  A  49 ( 1.3A) GLY  A  47 ( 0.0A)	1.26A	4fimA-4kqnA: undetectable	4fimA-4kqnA: 21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G19_A_ACTA304_0 (GLUTATHIONE TRANSFERASE GTE1)	3e2s	PROLINE DEHYDROGENASE (Escherichia coli)	4 / 5	ILE A 328 LEU A 330 LYS A 329 ASN A 368	None None PRO  A   1 (-2.8A) None	1.08A	4g19A-3e2sA: undetectable	4g19A-3e2sA: 19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G5J_A_0WMA1102_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3bpo	INTERLEUKIN-13 RECEPTOR ALPHA-1 CHAIN (Homo sapiens)	4 / 7	PHE C 183 TYR C 158 ILE C 213 PRO C 148	PHE  C 183 ( 1.3A) TYR  C 158 ( 1.3A) ILE  C 213 ( 0.6A) PRO  C 148 ( 1.1A)	0.78A	4g5jA-3bpoC: undetectable	4g5jA-3bpoC: 20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G5J_A_0WMA1102_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4non	FERROUS IRON UPTAKE TRANSPORTER PROTEIN B (Streptococcus thermophilus)	4 / 7	PHE A 250 TYR A 172 ILE A 201 PRO A 170	PHE  A 250 ( 1.3A) TYR  A 172 ( 1.3A) ILE  A 201 ( 0.7A) PRO  A 170 ( 1.1A)	0.98A	4g5jA-4nonA: undetectable	4g5jA-4nonA: 24.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HVC_A_HFGA1602_0 (BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	9 / 12	GLU A1100 VAL A1101 TRP A1169 GLU A1171 HIS A1173 PHE A1216 THR A1240 SER A1272 GLY A1274	None None None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) PRO  A1602 (-4.3A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.87A	4hvcA-5vadA: 54.1	4hvcA-5vadA: 98.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HVC_A_HFGA1602_0 (BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	5 / 12	GLU A1154 PHE A1216 THR A1240 SER A1272 GLY A1274	91Y  A1601 (-4.6A) PRO  A1602 (-4.3A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.84A	4hvcA-5vadA: 54.1	4hvcA-5vadA: 98.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HVC_A_HFGA1602_0 (BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	9 / 12	VAL A1101 PRO A1120 TRP A1169 GLU A1171 HIS A1173 PHE A1216 THR A1240 SER A1272 GLY A1274	None None None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) PRO  A1602 (-4.3A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.64A	4hvcA-5vadA: 54.1	4hvcA-5vadA: 98.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HVC_A_HFGA1602_1 (BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	4 / 4	THR A1121 GLU A1123 ARG A1152 HIS A1242	PRO  A1602 (-3.5A) PRO  A1602 (-2.8A) PRO  A1602 ( 3.4A) PRO  A1602 (-4.1A)	0.45A	4hvcA-5vadA: 54.1	4hvcA-5vadA: 98.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HVC_B_HFGB1602_0 (BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	5 / 12	GLU A1154 PHE A1216 THR A1240 SER A1272 GLY A1274	91Y  A1601 (-4.6A) PRO  A1602 (-4.3A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.94A	4hvcB-5vadA: 54.2	4hvcB-5vadA: 98.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HVC_B_HFGB1602_0 (BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	10 / 12	LEU A1087 GLU A1100 VAL A1101 PRO A1120 GLU A1171 HIS A1173 PHE A1216 THR A1240 SER A1272 GLY A1274	None None None None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) PRO  A1602 (-4.3A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.86A	4hvcB-5vadA: 54.2	4hvcB-5vadA: 98.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HVC_B_HFGB1602_0 (BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	10 / 12	LEU A1087 GLU A1100 VAL A1101 PRO A1120 TRP A1169 GLU A1171 HIS A1173 THR A1240 SER A1272 GLY A1274	None None None None None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.66A	4hvcB-5vadA: 54.2	4hvcB-5vadA: 98.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HVC_B_HFGB1602_1 (BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	4 / 5	THR A1121 GLU A1123 ARG A1152 HIS A1242	PRO  A1602 (-3.5A) PRO  A1602 (-2.8A) PRO  A1602 ( 3.4A) PRO  A1602 (-4.1A)	0.40A	4hvcB-5vadA: 54.2	4hvcB-5vadA: 98.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HVR_A_SALA203_1 (3-HYDROXYANTHRANILAT E 3,4-DIOXYGENASE)	1wly	2-HALOACRYLATE REDUCTASE (Burkholderia sp. WS)	4 / 7	GLU A  19 HIS A   8 PRO A  61 VAL A  21	GLU  A  19 ( 0.6A) HIS  A   8 ( 1.0A) PRO  A  61 ( 1.1A) VAL  A  21 ( 0.6A)	1.03A	4hvrA-1wlyA: undetectable	4hvrA-1wlyA: 16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IV0_A_SAMA302_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE)	5mc5	XAA-PRO DIPEPTIDASE (Homo sapiens)	5 / 12	GLY A 447 ILE A 418 ARG A 265 SER A 251 LEU A 254	None None None None PRO  A 504 (-4.5A)	1.05A	4iv0A-5mc5A: undetectable	4iv0A-5mc5A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J4V_A_SVRA301_1 (NUCLEOCAPSID PROTEIN)	3i4k	MUCONATE LACTONIZING ENZYME (Corynebacterium glutamicum)	5 / 11	GLY A 310 GLN A 316 PRO A 333 PHE A 345 ILE A 341	GLY  A 310 ( 0.0A) GLN  A 316 ( 0.6A) PRO  A 333 ( 1.1A) PHE  A 345 ( 1.3A) ILE  A 341 ( 0.3A)	1.13A	4j4vA-3i4kA: undetectable	4j4vA-3i4kA: 21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J4V_A_SVRA301_1 (NUCLEOCAPSID PROTEIN)	5hxk	ZINC-DEPENDENT PEPTIDASE (Thermus thermophilus)	5 / 11	GLY A 188 ALA A 353 VAL A 186 PRO A  91 PHE A  89	GLY  A 188 ( 0.0A) ALA  A 353 ( 0.0A) VAL  A 186 ( 0.6A) PRO  A  91 ( 1.1A) PHE  A  89 ( 1.3A)	1.48A	4j4vA-5hxkA: undetectable	4j4vA-5hxkA: 22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J4V_B_SVRB301_1 (NUCLEOCAPSID PROTEIN)	5hxk	ZINC-DEPENDENT PEPTIDASE (Thermus thermophilus)	5 / 10	GLY A 188 ALA A 353 VAL A 186 PRO A  91 PHE A  89	GLY  A 188 ( 0.0A) ALA  A 353 ( 0.0A) VAL  A 186 ( 0.6A) PRO  A  91 ( 1.1A) PHE  A  89 ( 1.3A)	1.44A	4j4vB-5hxkA: 0.7	4j4vB-5hxkA: 22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J4V_C_SVRC301_1 (NUCLEOCAPSID PROTEIN)	4yzr	POLYKETIDE BIOSYNTHESIS CYTOCHROME P450 PKSS (Bacillus subtilis)	4 / 8	GLY A 318 ASN A 321 ARG A 337 PRO A  17	GLY  A 318 ( 0.0A) ASN  A 321 ( 0.6A) ARG  A 337 ( 0.6A) PRO  A  17 ( 1.0A)	0.94A	4j4vC-4yzrA: 2.5	4j4vC-4yzrA: 19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J4V_D_SVRD301_1 (NUCLEOCAPSID PROTEIN)	3i4k	MUCONATE LACTONIZING ENZYME (Corynebacterium glutamicum)	5 / 11	ALA A 119 GLN A 316 PRO A 333 PHE A 345 ILE A 341	ALA  A 119 ( 0.0A) GLN  A 316 ( 0.6A) PRO  A 333 ( 1.1A) PHE  A 345 ( 1.3A) ILE  A 341 ( 0.3A)	1.43A	4j4vD-3i4kA: undetectable 4j4vE-3i4kA: undetectable	4j4vD-3i4kA: 21.29 4j4vE-3i4kA: 21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J4V_D_SVRD301_1 (NUCLEOCAPSID PROTEIN)	3i4k	MUCONATE LACTONIZING ENZYME (Corynebacterium glutamicum)	5 / 11	GLY A 310 GLN A 316 PRO A 333 PHE A 345 ILE A 341	GLY  A 310 ( 0.0A) GLN  A 316 ( 0.6A) PRO  A 333 ( 1.1A) PHE  A 345 ( 1.3A) ILE  A 341 ( 0.3A)	1.27A	4j4vD-3i4kA: undetectable 4j4vE-3i4kA: undetectable	4j4vD-3i4kA: 21.29 4j4vE-3i4kA: 21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J4V_E_SVRE301_1 (NUCLEOCAPSID PROTEIN)	5hxk	ZINC-DEPENDENT PEPTIDASE (Thermus thermophilus)	5 / 10	GLY A 188 ALA A 353 VAL A 186 PRO A  91 PHE A  89	GLY  A 188 ( 0.0A) ALA  A 353 ( 0.0A) VAL  A 186 ( 0.6A) PRO  A  91 ( 1.1A) PHE  A  89 ( 1.3A)	1.47A	4j4vA-5hxkA: undetectable 4j4vE-5hxkA: 0.0	4j4vA-5hxkA: 22.25 4j4vE-5hxkA: 22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K17_B_OHBB701_0 (LEUCINE-RICH REPEAT-CONTAINING PROTEIN 16A)	4kqn	D-HYDANTOINASE (Bacillus sp. AR9)	4 / 5	GLU A 185 ARG A 212 PRO A 289 SER A 241	GLU  A 185 ( 0.5A) ARG  A 212 ( 0.6A) PRO  A 289 ( 1.1A) SER  A 241 ( 0.0A)	1.38A	4k17B-4kqnA: undetectable	4k17B-4kqnA: 20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K7G_B_ACTB902_0 (3-HYDROXYPROLINE DEHYDRATSE)	5wpi	HSVA (Erwinia amylovora)	4 / 7	ASP A  36 PRO A  96 HIS A 101 SER A  99	ASP  A  36 ( 0.6A) PRO  A  96 ( 1.1A) HIS  A 101 ( 1.0A) SER  A  99 ( 0.0A)	1.16A	4k7gB-5wpiA: undetectable	4k7gB-5wpiA: 23.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4K87_A_ADNA602_1 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	5 / 8	ARG A1152 PHE A1167 GLN A1237 GLY A1238 THR A1276	PRO  A1602 ( 3.4A) 91Y  A1601 (-3.8A) 91Y  A1601 (-4.1A) None 91Y  A1601 (-3.0A)	1.21A	4k87A-5vadA: 54.9	4k87A-5vadA: 96.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4K87_A_ADNA602_1 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	7 / 8	ARG A1152 PHE A1167 GLN A1237 GLY A1239 THR A1240 THR A1276 ARG A1278	PRO  A1602 ( 3.4A) 91Y  A1601 (-3.8A) 91Y  A1601 (-4.1A) 91Y  A1601 ( 4.1A) 91Y  A1601 (-4.2A) 91Y  A1601 (-3.0A) 91Y  A1601 (-3.4A)	0.35A	4k87A-5vadA: 54.9	4k87A-5vadA: 96.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4K88_A_HFGA602_0 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	7 / 12	GLU A1154 PRO A1120 GLU A1123 GLU A1171 PHE A1216 HIS A1242 SER A1272	91Y  A1601 (-4.6A) None PRO  A1602 (-2.8A) PRO  A1602 ( 4.7A) PRO  A1602 (-4.3A) PRO  A1602 (-4.1A) PRO  A1602 (-3.3A)	1.05A	4k88A-5vadA: 51.8	4k88A-5vadA: 96.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4K88_A_HFGA602_0 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	9 / 12	GLU A1154 PRO A1120 THR A1121 GLU A1123 ARG A1152 TRP A1169 GLU A1171 HIS A1242 SER A1272	91Y  A1601 (-4.6A) None PRO  A1602 (-3.5A) PRO  A1602 (-2.8A) PRO  A1602 ( 3.4A) None PRO  A1602 ( 4.7A) PRO  A1602 (-4.1A) PRO  A1602 (-3.3A)	0.94A	4k88A-5vadA: 51.8	4k88A-5vadA: 96.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4K88_A_HFGA602_0 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	7 / 12	VAL A1101 PRO A1120 GLU A1123 GLU A1171 PHE A1216 HIS A1242 SER A1272	None None PRO  A1602 (-2.8A) PRO  A1602 ( 4.7A) PRO  A1602 (-4.3A) PRO  A1602 (-4.1A) PRO  A1602 (-3.3A)	0.83A	4k88A-5vadA: 51.8	4k88A-5vadA: 96.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4K88_A_HFGA602_0 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	9 / 12	VAL A1101 PRO A1120 THR A1121 GLU A1123 ARG A1152 TRP A1169 GLU A1171 HIS A1242 SER A1272	None None PRO  A1602 (-3.5A) PRO  A1602 (-2.8A) PRO  A1602 ( 3.4A) None PRO  A1602 ( 4.7A) PRO  A1602 (-4.1A) PRO  A1602 (-3.3A)	0.64A	4k88A-5vadA: 51.8	4k88A-5vadA: 96.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KF9_A_ACTA408_0 (GLUTATHIONE S-TRANSFERASE PROTEIN)	3i4k	MUCONATE LACTONIZING ENZYME (Corynebacterium glutamicum)	4 / 6	TYR A 340 THR A 339 PRO A 333 PHE A 345	TYR  A 340 ( 1.3A) THR  A 339 ( 0.8A) PRO  A 333 ( 1.1A) PHE  A 345 ( 1.3A)	1.30A	4kf9A-3i4kA: undetectable	4kf9A-3i4kA: 25.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KLR_A_CHDA505_0 (FERROCHELATASE, MITOCHONDRIAL)	5wpi	HSVA (Erwinia amylovora)	4 / 5	LEU A 354 PRO A 121 LEU A 125 ILE A 132	LEU  A 354 ( 0.6A) PRO  A 121 ( 1.1A) LEU  A 125 ( 0.5A) ILE  A 132 ( 0.6A)	0.92A	4klrA-5wpiA: undetectable	4klrA-5wpiA: 23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KLR_A_CHDA505_0 (FERROCHELATASE, MITOCHONDRIAL)	6ezy	- (-)	4 / 5	LEU A 110 PRO A 109 LEU A 113 ILE A 179	LEU  A 110 ( 0.6A) PRO  A 109 ( 1.1A) LEU  A 113 ( 0.6A) ILE  A 179 ( 0.7A)	0.84A	4klrA-6ezyA: undetectable	4klrA-6ezyA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KLR_B_CHDB503_0 (FERROCHELATASE, MITOCHONDRIAL)	5ec3	4-HYDROXYPHENYLPYRUV ATE DIOXYGENASE (Homo sapiens)	4 / 8	LEU A 367 PRO A 239 SER A 226 GLY A 358	LEU  A 367 ( 0.6A) PRO  A 239 ( 1.1A) SER  A 226 ( 0.0A) GLY  A 358 ( 0.0A)	0.94A	4klrB-5ec3A: undetectable	4klrB-5ec3A: 22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KLR_B_CHDB504_0 (FERROCHELATASE, MITOCHONDRIAL)	1c8x	ENDO-BETA-N-ACETYLGL UCOSAMINIDASE H (Streptomyces plicatus)	3 / 3	LEU A  79 PRO A  78 ARG A 269	LEU  A  79 ( 0.6A) PRO  A  78 ( 1.1A) ARG  A 269 ( 0.6A)	0.66A	4klrB-1c8xA: undetectable	4klrB-1c8xA: 20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KMM_B_CHDB503_0 (FERROCHELATASE, MITOCHONDRIAL)	3icc	PUTATIVE 3-OXOACYL-(ACYL CARRIER PROTEIN) REDUCTASE (Bacillus anthracis)	4 / 5	LEU A 200 ARG A 217 PRO A 188 SER A 145	LEU  A 200 ( 0.6A) ARG  A 217 ( 0.6A) PRO  A 188 (-1.1A) SER  A 145 (-0.0A)	1.31A	4kmmB-3iccA: 3.4	4kmmB-3iccA: 20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOS_A_4KOA201_1 (UNCHARACTERIZED PROTEIN)	1v0f	ENDO-ALPHA-SIALIDASE (Enterobacteria phage K1F)	5 / 12	PRO A 372 TYR A 324 GLY A 346 ASN A 326 MET A 345	PRO  A 372 ( 1.1A) TYR  A 324 ( 1.3A) GLY  A 346 ( 0.0A) ASN  A 326 ( 0.6A) MET  A 345 ( 0.0A)	1.34A	4kosA-1v0fA: undetectable	4kosA-1v0fA: 12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOV_A_KOVA204_1 (UNCHARACTERIZED PROTEIN)	1v0f	ENDO-ALPHA-SIALIDASE (Enterobacteria phage K1F)	5 / 12	PRO A 372 TYR A 324 GLY A 346 ASN A 326 MET A 345	PRO  A 372 ( 1.1A) TYR  A 324 ( 1.3A) GLY  A 346 ( 0.0A) ASN  A 326 ( 0.6A) MET  A 345 ( 0.0A)	1.36A	4kovA-1v0fA: undetectable	4kovA-1v0fA: 12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOW_A_CFXA204_1 (UNCHARACTERIZED PROTEIN)	1v0f	ENDO-ALPHA-SIALIDASE (Enterobacteria phage K1F)	5 / 12	PRO A 372 TYR A 324 GLY A 346 ASN A 326 MET A 345	PRO  A 372 ( 1.1A) TYR  A 324 ( 1.3A) GLY  A 346 ( 0.0A) ASN  A 326 ( 0.6A) MET  A 345 ( 0.0A)	1.34A	4kowA-1v0fA: 0.0	4kowA-1v0fA: 12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOX_A_CLSA205_1 (UNCHARACTERIZED PROTEIN)	1v0f	ENDO-ALPHA-SIALIDASE (Enterobacteria phage K1F)	5 / 11	PRO A 372 TYR A 324 GLY A 346 ASN A 326 MET A 345	PRO  A 372 ( 1.1A) TYR  A 324 ( 1.3A) GLY  A 346 ( 0.0A) ASN  A 326 ( 0.6A) MET  A 345 ( 0.0A)	1.38A	4koxA-1v0fA: 0.0	4koxA-1v0fA: 12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOY_A_CSCA214_1 (UNCHARACTERIZED PROTEIN)	1v0f	ENDO-ALPHA-SIALIDASE (Enterobacteria phage K1F)	5 / 11	PRO A 372 TYR A 324 GLY A 346 ASN A 326 MET A 345	PRO  A 372 ( 1.1A) TYR  A 324 ( 1.3A) GLY  A 346 ( 0.0A) ASN  A 326 ( 0.6A) MET  A 345 ( 0.0A)	1.37A	4koyA-1v0fA: undetectable	4koyA-1v0fA: 12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L9Q_B_9TPB601_1 (SERUM ALBUMIN)	5hiu	GTPASE ACTIVATOR-LIKE PROTEIN (Chaetomium thermophilum)	5 / 12	LEU A 432 PRO A 442 ALA A 394 LEU A 405 GLY A 409	LEU  A 432 ( 0.6A) PRO  A 442 ( 1.1A) ALA  A 394 ( 0.0A) LEU  A 405 ( 0.5A) GLY  A 409 ( 0.0A)	1.23A	4l9qB-5hiuA: undetectable	4l9qB-5hiuA: 23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LB2_A_DM5A601_1 (SERUM ALBUMIN)	4egs	RIBOSE 5-PHOSPHATE ISOMERASE RPIB (Caldanaerobacter subterraneus)	4 / 7	LEU A 125 VAL A 127 PRO A 120 GLU A  53	LEU  A 125 ( 0.6A) VAL  A 127 ( 0.6A) PRO  A 120 ( 1.1A) GLU  A  53 ( 0.6A)	1.03A	4lb2A-4egsA: undetectable	4lb2A-4egsA: 15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LUH_A_ACTA608_0 (SERUM ALBUMIN)	1wly	2-HALOACRYLATE REDUCTASE (Burkholderia sp. WS)	4 / 4	PRO A 113 ASP A 115 LEU A 116 ARG A  87	PRO  A 113 ( 1.1A) ASP  A 115 ( 0.5A) LEU  A 116 ( 0.6A) ARG  A  87 ( 0.6A)	1.42A	4luhA-1wlyA: 0.0	4luhA-1wlyA: 19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M2X_G_TMQG202_1 (DIHYDROFOLATE REDUCTASE)	5nks	DIHYDROPYRIMIDINASE- RELATED PROTEIN 4 (Homo sapiens)	6 / 12	ASP A  87 GLN A  91 PRO A 463 VAL A 461 ILE A 104 THR A 335	ASP  A  87 ( 0.5A) GLN  A  91 ( 0.6A) PRO  A 463 ( 1.1A) VAL  A 461 ( 0.6A) ILE  A 104 ( 0.6A) THR  A 335 ( 0.8A)	1.21A	4m2xG-5nksA: undetectable	4m2xG-5nksA: 13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MK4_A_CHDA504_0 (FERROCHELATASE, MITOCHONDRIAL)	3ulk	KETOL-ACID REDUCTOISOMERASE (Escherichia coli)	4 / 8	PRO A 154 SER A 131 VAL A 152 GLY A 158	PRO  A 154 (-1.1A) SER  A 131 (-0.0A) VAL  A 152 ( 0.6A) GLY  A 158 ( 0.0A)	0.96A	4mk4A-3ulkA: 2.9	4mk4A-3ulkA: 21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MMB_A_SREA603_1 (TRANSPORTER)	3h7a	SHORT CHAIN DEHYDROGENASE (Rhodopseudomonas palustris)	5 / 9	PRO A 214 VAL A 217 ALA A 218 TYR A 221 GLY A  18	PRO  A 214 ( 1.1A) VAL  A 217 ( 0.6A) ALA  A 218 ( 0.0A) TYR  A 221 ( 1.3A) GLY  A  18 ( 0.0A)	1.05A	4mmbA-3h7aA: undetectable	4mmbA-3h7aA: 19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MMD_B_29EB603_1 (TRANSPORTER)	3h7a	SHORT CHAIN DEHYDROGENASE (Rhodopseudomonas palustris)	5 / 12	PRO A 214 VAL A 217 ALA A 218 TYR A 221 GLY A  18	PRO  A 214 ( 1.1A) VAL  A 217 ( 0.6A) ALA  A 218 ( 0.0A) TYR  A 221 ( 1.3A) GLY  A  18 ( 0.0A)	0.89A	4mmdB-3h7aA: undetectable	4mmdB-3h7aA: 19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MUB_A_OAQA302_0 (SULFOTRANSFERASE)	5xlu	GAMMA GLUTAMYL TRANSPEPTIDASE (Bacillus licheniformis)	5 / 12	PRO A 338 VAL A 343 GLY A 373 ASP A 330 PHE A 293	PRO  A 338 ( 1.1A) VAL  A 343 ( 0.5A) GLY  A 373 ( 0.0A) ASP  A 330 ( 0.5A) PHE  A 293 ( 1.3A)	1.45A	4mubA-5xluA: undetectable	4mubA-5xluA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MWZ_A_SAMA301_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE)	5mc5	XAA-PRO DIPEPTIDASE (Homo sapiens)	5 / 12	GLY A 447 ILE A 418 ARG A 265 SER A 251 LEU A 254	None None None None PRO  A 504 (-4.5A)	1.13A	4mwzA-5mc5A: undetectable	4mwzA-5mc5A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MWZ_B_SAMB301_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE)	5mc5	XAA-PRO DIPEPTIDASE (Homo sapiens)	5 / 12	GLY A 447 ILE A 418 ARG A 265 SER A 251 LEU A 254	None None None None PRO  A 504 (-4.5A)	1.05A	4mwzB-5mc5A: undetectable	4mwzB-5mc5A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O8Z_A_BBIA402_1 (NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-3, MITOCHONDRIAL)	3o96	RAC-ALPHA SERINE/THREONINE-PRO TEIN KINASE (Homo sapiens)	4 / 5	PHE A 408 PHE A 407 LEU A 384 PRO A 348	PHE  A 408 ( 1.3A) PHE  A 407 ( 1.3A) LEU  A 384 ( 0.6A) PRO  A 348 ( 1.1A)	1.23A	4o8zA-3o96A: undetectable	4o8zA-3o96A: 21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ODR_B_FK5B201_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SLYD, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP1A CHIMERA)	5hfi	UNCHARACTERIZED PROTEIN, CYTOSOLIC DISULFIDE REDUCTASE DSBM (Pseudomonas aeruginosa)	5 / 11	PRO A  95 TYR A  10 LEU A  37 LEU A  24 ILE A 127	PRO  A  95 ( 1.1A) TYR  A  10 ( 1.3A) LEU  A  37 ( 0.5A) LEU  A  24 ( 0.6A) ILE  A 127 ( 0.7A)	1.09A	4odrA-5hfiA: undetectable 4odrB-5hfiA: undetectable	4odrA-5hfiA: 18.49 4odrB-5hfiA: 18.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4OLF_A_HFGA802_0 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	10 / 12	GLU A1100 VAL A1101 TRP A1169 GLU A1171 HIS A1173 PHE A1216 THR A1240 SER A1272 TRP A1273 GLY A1274	None None None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) PRO  A1602 (-4.3A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.3A) None PRO  A1602 (-3.7A)	0.74A	4olfA-5vadA: 49.5	4olfA-5vadA: 50.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4OLF_A_HFGA802_0 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	7 / 12	GLU A1154 TRP A1169 PHE A1216 THR A1240 SER A1272 TRP A1273 GLY A1274	91Y  A1601 (-4.6A) None PRO  A1602 (-4.3A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.3A) None PRO  A1602 (-3.7A)	0.89A	4olfA-5vadA: 49.5	4olfA-5vadA: 50.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4OLF_A_HFGA802_0 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	10 / 12	VAL A1101 PRO A1120 TRP A1169 GLU A1171 HIS A1173 PHE A1216 THR A1240 SER A1272 TRP A1273 GLY A1274	None None None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) PRO  A1602 (-4.3A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.3A) None PRO  A1602 (-3.7A)	0.56A	4olfA-5vadA: 49.5	4olfA-5vadA: 50.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4OLF_A_HFGA802_1 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	4 / 4	THR A1121 GLU A1123 ARG A1152 HIS A1242	PRO  A1602 (-3.5A) PRO  A1602 (-2.8A) PRO  A1602 ( 3.4A) PRO  A1602 (-4.1A)	0.51A	4olfA-5vadA: 49.5	4olfA-5vadA: 50.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PEV_B_ADNB501_1 (MEMBRANE LIPOPROTEIN FAMILY PROTEIN)	4rdc	AMINO ACID/AMIDE ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN, HAAT FAMILY (Trichormus variabilis)	5 / 12	VAL A 287 SER A 332 PHE A 331 GLY A 281 ASP A 280	None GOL  A 503 ( 3.9A) PRO  A 501 (-4.3A) PRO  A 501 ( 4.6A) PRO  A 501 (-3.7A)	1.20A	4pevB-4rdcA: 10.5	4pevB-4rdcA: 24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PEV_B_ADNB501_2 (MEMBRANE LIPOPROTEIN FAMILY PROTEIN)	1ryn	PROTEIN CRS2 (Zea mays)	3 / 3	PRO A  99 LEU A  98 GLN A 192	PRO  A  99 ( 1.1A) LEU  A  98 ( 0.5A) GLN  A 192 ( 0.6A)	0.53A	4pevB-1rynA: 5.0	4pevB-1rynA: 20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PEV_B_ADNB501_2 (MEMBRANE LIPOPROTEIN FAMILY PROTEIN)	4hne	PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2-ALPHA (Homo sapiens)	3 / 3	PRO A 283 LEU A 282 GLN A 289	PRO  A 283 ( 1.1A) LEU  A 282 ( 0.6A) GLN  A 289 ( 0.6A)	0.58A	4pevB-4hneA: undetectable	4pevB-4hneA: 22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q15_A_HFGA803_0 (PROLINE--TRNA LIGASE)	3wd7	TYPE III POLYKETIDE SYNTHASES ACRIDONE SYNTHASE (Citrus x microcarpa)	5 / 12	PRO A 196 THR A 197 ARG A  94 SER A 208 GLY A 200	PRO  A 196 ( 1.1A) THR  A 197 ( 0.8A) ARG  A  94 ( 0.6A) SER  A 208 ( 0.0A) GLY  A 200 ( 0.0A)	1.32A	4q15A-3wd7A: undetectable	4q15A-3wd7A: 22.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4Q15_A_HFGA803_0 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	10 / 12	LEU A1087 GLU A1100 VAL A1101 PRO A1120 THR A1121 ARG A1152 TRP A1169 HIS A1173 SER A1272 GLY A1274	None None None None PRO  A1602 (-3.5A) PRO  A1602 ( 3.4A) None PRO  A1602 ( 4.5A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.78A	4q15A-5vadA: 48.5	4q15A-5vadA: 50.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4Q15_A_HFGA803_0 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	9 / 12	LEU A1087 GLU A1100 VAL A1101 PRO A1120 TRP A1169 HIS A1173 PHE A1216 SER A1272 GLY A1274	None None None None None PRO  A1602 ( 4.5A) PRO  A1602 (-4.3A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.95A	4q15A-5vadA: 48.5	4q15A-5vadA: 50.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4Q15_A_HFGA803_1 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	3 / 3	GLU A1123 THR A1240 HIS A1242	PRO  A1602 (-2.8A) 91Y  A1601 (-4.2A) PRO  A1602 (-4.1A)	0.45A	4q15A-5vadA: 48.5	4q15A-5vadA: 50.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q15_B_HFGB803_0 (PROLINE--TRNA LIGASE)	3wd7	TYPE III POLYKETIDE SYNTHASES ACRIDONE SYNTHASE (Citrus x microcarpa)	5 / 12	PRO A 196 THR A 197 ARG A  94 SER A 208 GLY A 200	PRO  A 196 ( 1.1A) THR  A 197 ( 0.8A) ARG  A  94 ( 0.6A) SER  A 208 ( 0.0A) GLY  A 200 ( 0.0A)	1.32A	4q15B-3wd7A: undetectable	4q15B-3wd7A: 22.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4Q15_B_HFGB803_0 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	9 / 12	LEU A1087 GLU A1100 VAL A1101 PRO A1120 THR A1121 ARG A1152 TRP A1169 GLU A1171 GLY A1274	None None None None PRO  A1602 (-3.5A) PRO  A1602 ( 3.4A) None PRO  A1602 ( 4.7A) PRO  A1602 (-3.7A)	0.74A	4q15B-5vadA: 48.5	4q15B-5vadA: 50.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4Q15_B_HFGB803_0 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	8 / 12	LEU A1087 GLU A1100 VAL A1101 PRO A1120 TRP A1169 GLU A1171 PHE A1216 GLY A1274	None None None None None PRO  A1602 ( 4.7A) PRO  A1602 (-4.3A) PRO  A1602 (-3.7A)	0.95A	4q15B-5vadA: 48.5	4q15B-5vadA: 50.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4Q15_B_HFGB803_0 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	9 / 12	LEU A1087 VAL A1101 PRO A1120 THR A1121 ARG A1152 TRP A1169 GLU A1171 SER A1272 GLY A1274	None None None PRO  A1602 (-3.5A) PRO  A1602 ( 3.4A) None PRO  A1602 ( 4.7A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.56A	4q15B-5vadA: 48.5	4q15B-5vadA: 50.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4Q15_B_HFGB803_0 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	8 / 12	LEU A1087 VAL A1101 PRO A1120 TRP A1169 GLU A1171 PHE A1216 SER A1272 GLY A1274	None None None None PRO  A1602 ( 4.7A) PRO  A1602 (-4.3A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.76A	4q15B-5vadA: 48.5	4q15B-5vadA: 50.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4Q15_B_HFGB803_1 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	3 / 3	GLU A1123 THR A1240 HIS A1242	PRO  A1602 (-2.8A) 91Y  A1601 (-4.2A) PRO  A1602 (-4.1A)	0.50A	4q15B-5vadA: 48.5	4q15B-5vadA: 50.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QN9_B_DXCB610_0 (N-ACYL-PHOSPHATIDYLE THANOLAMINE-HYDROLYZ ING PHOSPHOLIPASE D)	1wly	2-HALOACRYLATE REDUCTASE (Burkholderia sp. WS)	3 / 3	GLY A  12 PRO A  13 ALA A 311	GLY  A  12 ( 0.0A) PRO  A  13 ( 1.1A) ALA  A 311 ( 0.0A)	0.53A	4qn9B-1wlyA: undetectable	4qn9B-1wlyA: 18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QWP_B_GCSB305_1 (CHITOSANASE)	4w65	GLYCOSYL HYDROLASE FAMILY PROTEIN (Mycolicibacteriu m fortuitum)	3 / 3	GLY A  89 PRO A  88 GLN A  93	GLY  A  89 ( 0.0A) PRO  A  88 ( 1.1A) GLN  A  93 ( 0.6A)	0.52A	4qwpB-4w65A: undetectable	4qwpB-4w65A: 18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UAC_A_ACRA501_2 (CARBOHYDRATE ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN, CUT1 FAMILY (TC 3.A.1.1.-))	4mwt	LYSOSOMAL PROTECTIVE PROTEIN (Homo sapiens)	4 / 7	PRO A 432 GLU A 149 ASP A  78 THR A 311	PRO  A 432 ( 1.1A) GLU  A 149 ( 0.5A) ASP  A  78 ( 0.6A) THR  A 311 ( 0.8A)	1.26A	4uacA-4mwtA: undetectable	4uacA-4mwtA: 22.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4UIL_H_QI9H1223_0 (FAB 314.1)	1fgv	H52 FV (HEAVY CHAIN) H52 FV (LIGHT CHAIN) (Homo sapiens; Homo sapiens)	8 / 12	HIS H  35 GLY H 101 PHE H 111 GLN L  89 GLN L  90 GLY L  91 LEU L  94 PRO L  96	HIS  H  35 ( 1.0A) GLY  H 101 ( 0.0A) PHE  H 111 ( 1.3A) GLN  L  89 ( 0.6A) GLN  L  90 ( 0.6A) GLY  L  91 ( 0.0A) LEU  L  94 ( 0.6A) PRO  L  96 ( 1.1A)	0.85A	4uilH-1fgvH: 20.2 4uilL-1fgvH: 5.2	4uilH-1fgvH: 53.23 4uilL-1fgvH: 19.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4UIL_H_QI9H1223_0 (FAB 314.1)	1fgv	H52 FV (HEAVY CHAIN) H52 FV (LIGHT CHAIN) (Homo sapiens; Homo sapiens)	8 / 12	HIS H  35 SER H  59 PHE H 111 GLN L  89 GLN L  90 GLY L  91 LEU L  94 PRO L  96	HIS  H  35 ( 1.0A) SER  H  59 ( 0.0A) PHE  H 111 ( 1.3A) GLN  L  89 ( 0.6A) GLN  L  90 ( 0.6A) GLY  L  91 ( 0.0A) LEU  L  94 ( 0.6A) PRO  L  96 ( 1.1A)	1.00A	4uilH-1fgvH: 20.2 4uilL-1fgvH: 5.2	4uilH-1fgvH: 53.23 4uilL-1fgvH: 19.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4UIN_H_QI9H1226_0 (FAB 314.3)	1fgv	H52 FV (HEAVY CHAIN) H52 FV (LIGHT CHAIN) (Homo sapiens; Homo sapiens)	6 / 12	HIS H  35 GLY H 101 PHE H 111 GLY L  91 LEU L  94 PRO L  96	HIS  H  35 ( 1.0A) GLY  H 101 ( 0.0A) PHE  H 111 ( 1.3A) GLY  L  91 ( 0.0A) LEU  L  94 ( 0.6A) PRO  L  96 ( 1.1A)	0.84A	4uinH-1fgvH: 21.2 4uinL-1fgvH: 13.6	4uinH-1fgvH: 52.42 4uinL-1fgvH: 20.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4UIN_H_QI9H1226_0 (FAB 314.3)	1fgv	H52 FV (HEAVY CHAIN) H52 FV (LIGHT CHAIN) (Homo sapiens; Homo sapiens)	6 / 12	HIS H  35 TRP H  47 PHE H 111 GLY L  91 LEU L  94 PRO L  96	HIS  H  35 ( 1.0A) TRP  H  47 ( 0.4A) PHE  H 111 ( 1.3A) GLY  L  91 ( 0.0A) LEU  L  94 ( 0.6A) PRO  L  96 ( 1.1A)	0.73A	4uinH-1fgvH: 21.2 4uinL-1fgvH: 13.6	4uinH-1fgvH: 52.42 4uinL-1fgvH: 20.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4UIN_H_QI9H1226_0 (FAB 314.3)	1fgv	H52 FV (HEAVY CHAIN) H52 FV (LIGHT CHAIN) (Homo sapiens; Homo sapiens)	6 / 12	TRP H  47 SER H  59 PHE H 111 GLY L  91 LEU L  94 PRO L  96	TRP  H  47 ( 0.4A) SER  H  59 ( 0.0A) PHE  H 111 ( 1.3A) GLY  L  91 ( 0.0A) LEU  L  94 ( 0.6A) PRO  L  96 ( 1.1A)	0.91A	4uinH-1fgvH: 21.2 4uinL-1fgvH: 13.6	4uinH-1fgvH: 52.42 4uinL-1fgvH: 20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4URO_B_NOVB2000_1 (DNA GYRASE SUBUNIT B)	4g9k	ROTENONE-INSENSITIVE NADH-UBIQUINONE OXIDOREDUCTASE (Saccharomyces cerevisiae)	5 / 12	SER A  83 GLU A 128 PRO A 345 ILE A 347 SER A 174	SER  A  83 (-0.0A) GLU  A 128 (-0.5A) PRO  A 345 ( 1.1A) ILE  A 347 ( 0.7A) SER  A 174 ( 0.0A)	1.31A	4uroB-4g9kA: undetectable	4uroB-4g9kA: 21.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YDQ_A_HFGA802_0 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	5 / 12	GLU A1154 ARG A1152 TRP A1169 SER A1272 GLY A1274	91Y  A1601 (-4.6A) PRO  A1602 ( 3.4A) None PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	1.12A	4ydqA-5vadA: 49.2	4ydqA-5vadA: 50.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YDQ_A_HFGA802_0 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	6 / 12	LEU A1087 GLU A1100 VAL A1101 ARG A1152 GLU A1171 GLY A1274	None None None PRO  A1602 ( 3.4A) PRO  A1602 ( 4.7A) PRO  A1602 (-3.7A)	0.87A	4ydqA-5vadA: 49.2	4ydqA-5vadA: 50.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YDQ_A_HFGA802_0 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	6 / 12	LEU A1087 GLU A1100 VAL A1101 ARG A1152 TRP A1169 GLY A1274	None None None PRO  A1602 ( 3.4A) None PRO  A1602 (-3.7A)	1.06A	4ydqA-5vadA: 49.2	4ydqA-5vadA: 50.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YDQ_A_HFGA802_0 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	5 / 12	LEU A1087 PHE A1097 VAL A1101 PHE A1216 GLY A1172	None None None PRO  A1602 (-4.3A) None	1.30A	4ydqA-5vadA: 49.2	4ydqA-5vadA: 50.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YDQ_A_HFGA802_0 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	8 / 12	LEU A1087 VAL A1101 PRO A1120 ARG A1152 GLU A1171 HIS A1173 SER A1272 GLY A1274	None None None PRO  A1602 ( 3.4A) PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.61A	4ydqA-5vadA: 49.2	4ydqA-5vadA: 50.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YDQ_A_HFGA802_0 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	7 / 12	LEU A1087 VAL A1101 PRO A1120 ARG A1152 TRP A1169 SER A1272 GLY A1274	None None None PRO  A1602 ( 3.4A) None PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.86A	4ydqA-5vadA: 49.2	4ydqA-5vadA: 50.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YDQ_A_HFGA802_0 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	8 / 12	LEU A1087 VAL A1101 PRO A1120 GLU A1171 HIS A1173 PHE A1216 SER A1272 GLY A1274	None None None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) PRO  A1602 (-4.3A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.76A	4ydqA-5vadA: 49.2	4ydqA-5vadA: 50.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YDQ_A_HFGA802_1 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	4 / 4	THR A1121 GLU A1123 THR A1240 HIS A1242	PRO  A1602 (-3.5A) PRO  A1602 (-2.8A) 91Y  A1601 (-4.2A) PRO  A1602 (-4.1A)	0.54A	4ydqA-5vadA: 49.2	4ydqA-5vadA: 50.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YDQ_B_HFGB802_0 (PROLINE--TRNA LIGASE)	3wd7	TYPE III POLYKETIDE SYNTHASES ACRIDONE SYNTHASE (Citrus x microcarpa)	5 / 12	PRO A 196 THR A 197 ARG A  94 SER A 208 GLY A 200	PRO  A 196 ( 1.1A) THR  A 197 ( 0.8A) ARG  A  94 ( 0.6A) SER  A 208 ( 0.0A) GLY  A 200 ( 0.0A)	1.29A	4ydqB-3wd7A: undetectable	4ydqB-3wd7A: 21.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YDQ_B_HFGB802_0 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	5 / 12	GLU A1154 ARG A1152 TRP A1169 SER A1272 GLY A1274	91Y  A1601 (-4.6A) PRO  A1602 ( 3.4A) None PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	1.12A	4ydqB-5vadA: 49.2	4ydqB-5vadA: 50.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YDQ_B_HFGB802_0 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	8 / 12	VAL A1101 PRO A1120 THR A1121 ARG A1152 GLU A1171 HIS A1173 SER A1272 GLY A1274	None None PRO  A1602 (-3.5A) PRO  A1602 ( 3.4A) PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.49A	4ydqB-5vadA: 49.2	4ydqB-5vadA: 50.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YDQ_B_HFGB802_0 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	8 / 12	VAL A1101 PRO A1120 THR A1121 ARG A1152 TRP A1169 HIS A1173 SER A1272 GLY A1274	None None PRO  A1602 (-3.5A) PRO  A1602 ( 3.4A) None PRO  A1602 ( 4.5A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.79A	4ydqB-5vadA: 49.2	4ydqB-5vadA: 50.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YDQ_B_HFGB802_0 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	8 / 12	VAL A1101 PRO A1120 THR A1121 GLU A1171 HIS A1173 PHE A1216 SER A1272 GLY A1274	None None PRO  A1602 (-3.5A) PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) PRO  A1602 (-4.3A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.69A	4ydqB-5vadA: 49.2	4ydqB-5vadA: 50.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YDQ_B_HFGB802_1 (PROLINE--TRNA LIGASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	3 / 3	GLU A1123 THR A1240 HIS A1242	PRO  A1602 (-2.8A) 91Y  A1601 (-4.2A) PRO  A1602 (-4.1A)	0.40A	4ydqB-5vadA: 49.2	4ydqB-5vadA: 50.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YOA_A_017A100_1 (HIV-1 PROTEASE)	2an1	PUTATIVE KINASE (Salmonella enterica)	4 / 6	ASP A 264 THR A 183 PRO A 184 THR A 185	ASP  A 264 ( 0.6A) THR  A 183 ( 0.8A) PRO  A 184 ( 1.1A) THR  A 185 ( 0.8A)	1.14A	4yoaA-2an1A: undetectable	4yoaA-2an1A: 17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YV5_A_SVRA205_2 (BASIC PHOSPHOLIPASE A2 HOMOLOG 2)	3s6f	HYPOTHETICAL ACETYLTRANSFERASE (Deinococcus radiodurans)	4 / 6	LEU A  66 ASN A  64 PRO A  76 ARG A 134	LEU  A  66 ( 0.5A) ASN  A  64 ( 0.6A) PRO  A  76 ( 1.1A) ARG  A 134 ( 0.6A)	1.27A	4yv5B-3s6fA: undetectable	4yv5B-3s6fA: 18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YV5_B_SVRB207_1 (BASIC PHOSPHOLIPASE A2 HOMOLOG 2)	3s6f	HYPOTHETICAL ACETYLTRANSFERASE (Deinococcus radiodurans)	4 / 6	LEU A  66 ASN A  64 PRO A  76 ARG A 134	LEU  A  66 ( 0.5A) ASN  A  64 ( 0.6A) PRO  A  76 ( 1.1A) ARG  A 134 ( 0.6A)	1.27A	4yv5A-3s6fA: undetectable	4yv5A-3s6fA: 18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZJ8_A_SUVA2001_2 (HUMAN OX1R FUSION PROTEIN TO P.ABYSII GLYCOGEN SYNTHASE)	5wpi	HSVA (Erwinia amylovora)	4 / 6	TRP A 279 PRO A 256 ILE A 128 VAL A  20	TRP  A 279 ( 0.5A) PRO  A 256 ( 1.1A) ILE  A 128 ( 0.7A) VAL  A  20 ( 0.6A)	0.94A	4zj8A-5wpiA: undetectable	4zj8A-5wpiA: 20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ALC_L_TIQL1210_1 (ANTI-TICAGRELOR FAB 72, HEAVY CHAIN ANTI-TICAGRELOR FAB 72, LIGHT CHAIN)	2nvv	ACETYL-COA HYDROLASE/TRANSFERAS E FAMILY PROTEIN (Porphyromonas gingivalis)	5 / 9	ILE A  93 THR A  98 TYR A 100 PRO A  82 ASP A 102	ILE  A  93 ( 0.7A) THR  A  98 ( 0.8A) TYR  A 100 ( 1.3A) PRO  A  82 ( 1.1A) ASP  A 102 ( 0.6A)	1.50A	5alcH-2nvvA: 0.0	5alcH-2nvvA: 17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B6I_A_ADNA302_1 (FLUORINASE)	4w65	GLYCOSYL HYDROLASE FAMILY PROTEIN (Mycolicibacteriu m fortuitum)	4 / 7	ASP A 270 TYR A 267 PRO A 268 THR A 266	ASP  A 270 ( 0.5A) TYR  A 267 ( 1.3A) PRO  A 268 ( 1.1A) THR  A 266 ( 0.8A)	1.28A	5b6iA-4w65A: undetectable	5b6iA-4w65A: 22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5C0O_E_SAME301_0 (TRNA (ADENINE(58)-N(1))-M ETHYLTRANSFERASE TRMI)	3r64	NAD DEPENDENT BENZALDEHYDE DEHYDROGENASE (Corynebacterium glutamicum)	5 / 12	ALA A  62 PRO A 205 GLY A  18 GLY A 207 ALA A  54	ALA  A  62 ( 0.0A) PRO  A 205 ( 1.1A) GLY  A  18 ( 0.0A) GLY  A 207 ( 0.0A) ALA  A  54 ( 0.0A)	1.14A	5c0oE-3r64A: 4.3	5c0oE-3r64A: 20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CSY_B_ACRB601_2 (4-ALPHA-GLUCANOTRANS FERASE DPE1, CHLOROPLASTIC/AMYLOP LASTIC)	4kqn	D-HYDANTOINASE (Bacillus sp. AR9)	4 / 5	TYR A 210 HIS A 208 LEU A 291 PRO A 214	TYR  A 210 ( 1.3A) HIS  A 208 ( 1.0A) LEU  A 291 ( 0.6A) PRO  A 214 ( 1.1A)	1.18A	5csyB-4kqnA: 3.6	5csyB-4kqnA: 21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEI_A_SHHA2004_1 (HDAC6 PROTEIN)	2nvv	ACETYL-COA HYDROLASE/TRANSFERAS E FAMILY PROTEIN (Porphyromonas gingivalis)	5 / 12	PRO A  36 GLY A  22 PHE A  23 ASP A  68 LEU A  71	PRO  A  36 ( 1.1A) GLY  A  22 ( 0.0A) PHE  A  23 ( 1.3A) ASP  A  68 ( 0.5A) LEU  A  71 ( 0.6A)	1.24A	5eeiA-2nvvA: undetectable	5eeiA-2nvvA: 20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEI_B_SHHB801_1 (HDAC6 PROTEIN)	2nvv	ACETYL-COA HYDROLASE/TRANSFERAS E FAMILY PROTEIN (Porphyromonas gingivalis)	5 / 12	PRO A  36 GLY A  22 PHE A  23 ASP A  68 LEU A  71	PRO  A  36 ( 1.1A) GLY  A  22 ( 0.0A) PHE  A  23 ( 1.3A) ASP  A  68 ( 0.5A) LEU  A  71 ( 0.6A)	1.23A	5eeiB-2nvvA: 2.1	5eeiB-2nvvA: 20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESH_A_1YNA602_2 (LANOSTEROL 14-ALPHA DEMETHYLASE)	3cbt	PHOSPHATASE SC4828 (Streptomyces coelicolor)	4 / 5	TRP A 130 LEU A  58 PRO A 204 LEU A 138	TRP  A 130 (-0.5A) LEU  A  58 ( 0.6A) PRO  A 204 (-1.1A) LEU  A 138 ( 0.6A)	1.36A	5eshA-3cbtA: undetectable	5eshA-3cbtA: 17.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5F9Z_A_HFGA702_0 (AMINOACYL-TRNA SYNTHETASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	9 / 12	LEU A1087 GLU A1100 VAL A1101 ARG A1152 TRP A1169 GLU A1171 PHE A1216 SER A1272 GLY A1274	None None None PRO  A1602 ( 3.4A) None PRO  A1602 ( 4.7A) PRO  A1602 (-4.3A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.93A	5f9zA-5vadA: 47.9	5f9zA-5vadA: 54.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5F9Z_A_HFGA702_0 (AMINOACYL-TRNA SYNTHETASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	9 / 12	LEU A1087 VAL A1101 PRO A1120 ARG A1152 TRP A1169 GLU A1171 PHE A1216 SER A1272 GLY A1274	None None None PRO  A1602 ( 3.4A) None PRO  A1602 ( 4.7A) PRO  A1602 (-4.3A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.72A	5f9zA-5vadA: 47.9	5f9zA-5vadA: 54.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5F9Z_A_HFGA702_1 (AMINOACYL-TRNA SYNTHETASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	4 / 4	THR A1121 GLU A1123 THR A1240 HIS A1242	PRO  A1602 (-3.5A) PRO  A1602 (-2.8A) 91Y  A1601 (-4.2A) PRO  A1602 (-4.1A)	0.52A	5f9zA-5vadA: 47.9	5f9zA-5vadA: 54.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5F9Z_B_HFGB703_0 (AMINOACYL-TRNA SYNTHETASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	9 / 12	LEU A1087 GLU A1100 VAL A1101 PRO A1120 ARG A1152 TRP A1169 GLU A1171 SER A1272 GLY A1274	None None None None PRO  A1602 ( 3.4A) None PRO  A1602 ( 4.7A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.77A	5f9zB-5vadA: 48.4	5f9zB-5vadA: 54.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5F9Z_B_HFGB703_0 (AMINOACYL-TRNA SYNTHETASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	8 / 12	LEU A1087 VAL A1101 PRO A1120 TRP A1169 GLU A1171 PHE A1216 SER A1272 GLY A1274	None None None None PRO  A1602 ( 4.7A) PRO  A1602 (-4.3A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.72A	5f9zB-5vadA: 48.4	5f9zB-5vadA: 54.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5F9Z_B_HFGB703_1 (AMINOACYL-TRNA SYNTHETASE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	4 / 4	THR A1121 GLU A1123 THR A1240 HIS A1242	PRO  A1602 (-3.5A) PRO  A1602 (-2.8A) 91Y  A1601 (-4.2A) PRO  A1602 (-4.1A)	0.52A	5f9zB-5vadA: 48.4	5f9zB-5vadA: 54.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FCT_B_C2FB402_1 (THYMIDYLATE SYNTHASE)	3ijl	MUCONATE CYCLOISOMERASE (Bacteroides thetaiotaomicron)	3 / 3	ASN A 226 ASP A 348 GLY A 325	MG  A 386 ( 4.6A) PRO  A 384 (-3.4A) None	0.67A	5fctB-3ijlA: undetectable	5fctB-3ijlA: 22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FSA_B_X2NB590_2 (CYP51 VARIANT1)	2hk0	D-PSICOSE 3-EPIMERASE (Agrobacterium tumefaciens)	3 / 3	PRO A  68 LEU A 147 SER A 110	PRO  A  68 ( 1.1A) LEU  A 147 ( 0.6A) SER  A 110 ( 0.0A)	0.65A	5fsaB-2hk0A: undetectable	5fsaB-2hk0A: 20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HBS_A_RTLA201_1 (RETINOL-BINDING PROTEIN 1)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	4 / 8	LEU A 622 LEU A 561 THR A 534 TYR A 527	None None None PRO  A 802 (-4.7A)	1.18A	5hbsA-5yp3A: undetectable	5hbsA-5yp3A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IGJ_A_CTYA402_2 (MACROLIDE 2'-PHOSPHOTRANSFERAS E)	1gc7	RADIXIN (Mus musculus)	4 / 5	PRO A 154 LEU A 234 TYR A 201 PHE A  85	PRO  A 154 ( 1.1A) LEU  A 234 ( 0.6A) TYR  A 201 ( 1.3A) PHE  A  85 ( 1.3A)	1.26A	5igjA-1gc7A: undetectable	5igjA-1gc7A: 23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IGT_A_ERYA402_0 (MACROLIDE 2'-PHOSPHOTRANSFERAS E)	5ep8	PYRIMIDINE-NUCLEOSID E PHOSPHORYLASE (Bacillus subtilis)	5 / 12	PRO A 242 VAL A 411 ALA A 340 VAL A 395 GLY A 344	PRO  A 242 ( 1.1A) VAL  A 411 ( 0.6A) ALA  A 340 ( 0.0A) VAL  A 395 ( 0.5A) GLY  A 344 ( 0.0A)	1.03A	5igtA-5ep8A: undetectable	5igtA-5ep8A: 23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IL1_A_SAMA601_0 (METTL3)	2rci	TYPE-2BA CYTOLYTIC DELTA-ENDOTOXIN (Bacillus thuringiensis)	5 / 12	ILE A  83 PRO A 188 LEU A 220 PHE A  64 GLY A  66	ILE  A  83 ( 0.7A) PRO  A 188 ( 1.1A) LEU  A 220 ( 0.6A) PHE  A  64 ( 1.3A) GLY  A  66 ( 0.0A)	0.91A	5il1A-2rciA: undetectable	5il1A-2rciA: 21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JGL_A_SAMA301_0 (UBIE/COQ5 FAMILY METHYLTRANSFERASE, PUTATIVE)	4g9k	ROTENONE-INSENSITIVE NADH-UBIQUINONE OXIDOREDUCTASE (Saccharomyces cerevisiae)	5 / 12	ALA A 385 ALA A 387 ALA A 175 GLY A 382 PRO A 390	ALA  A 385 ( 0.0A) ALA  A 387 ( 0.0A) ALA  A 175 (-0.0A) GLY  A 382 (-0.0A) PRO  A 390 ( 1.1A)	1.46A	5jglA-4g9kA: 3.9	5jglA-4g9kA: 20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JGL_B_SAMB301_0 (UBIE/COQ5 FAMILY METHYLTRANSFERASE, PUTATIVE)	4g9k	ROTENONE-INSENSITIVE NADH-UBIQUINONE OXIDOREDUCTASE (Saccharomyces cerevisiae)	5 / 12	ALA A 385 ALA A 387 ALA A 175 GLY A 382 PRO A 390	ALA  A 385 ( 0.0A) ALA  A 387 ( 0.0A) ALA  A 175 (-0.0A) GLY  A 382 (-0.0A) PRO  A 390 ( 1.1A)	1.45A	5jglB-4g9kA: 3.0	5jglB-4g9kA: 20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JO9_A_SORA302_0 (RIBITOL 2-DEHYDROGENASE)	2ogs	THERMOSTABLE CARBOXYLESTERASE EST50 (Geobacillus stearothermophil us)	5 / 12	TYR A 138 LEU A 226 GLY A 276 PRO A 277 LEU A 225	TYR  A 138 ( 1.3A) LEU  A 226 ( 0.6A) GLY  A 276 ( 0.0A) PRO  A 277 ( 1.1A) LEU  A 225 ( 0.6A)	1.32A	5jo9A-2ogsA: 3.9	5jo9A-2ogsA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5K7U_A_SAMA601_0 (N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT)	2nvv	ACETYL-COA HYDROLASE/TRANSFERAS E FAMILY PROTEIN (Porphyromonas gingivalis)	5 / 12	ILE A 358 PRO A 469 LEU A 460 PHE A 359 HIS A 417	ILE  A 358 ( 0.7A) PRO  A 469 ( 1.1A) LEU  A 460 ( 0.6A) PHE  A 359 ( 1.3A) HIS  A 417 (-1.0A)	1.34A	5k7uA-2nvvA: undetectable	5k7uA-2nvvA: 17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5K7U_A_SAMA601_0 (N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT)	2rci	TYPE-2BA CYTOLYTIC DELTA-ENDOTOXIN (Bacillus thuringiensis)	5 / 12	ILE A  83 PRO A 188 LEU A 220 PHE A  64 GLY A  66	ILE  A  83 ( 0.7A) PRO  A 188 ( 1.1A) LEU  A 220 ( 0.6A) PHE  A  64 ( 1.3A) GLY  A  66 ( 0.0A)	0.90A	5k7uA-2rciA: undetectable	5k7uA-2rciA: 22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L1F_C_6ZPC902_1 (GLUTAMATE RECEPTOR 2)	4zke	SUPERKILLER PROTEIN 7 (Saccharomyces cerevisiae)	4 / 7	ASP A 376 PRO A 377 TYR A 380 ASN A 728	ASP  A 376 ( 0.6A) PRO  A 377 ( 1.1A) TYR  A 380 ( 1.3A) ASN  A 728 ( 0.6A)	1.02A	5l1fC-4zkeA: 4.6	5l1fC-4zkeA: 20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L1F_D_6ZPD902_1 (GLUTAMATE RECEPTOR 2)	2ogs	THERMOSTABLE CARBOXYLESTERASE EST50 (Geobacillus stearothermophil us)	5 / 10	SER A  81 ASP A  83 PRO A  33 LEU A  85 SER A 114	SER  A  81 ( 0.0A) ASP  A  83 ( 0.6A) PRO  A  33 ( 1.1A) LEU  A  85 ( 0.6A) SER  A 114 ( 0.0A)	1.49A	5l1fD-2ogsA: 2.7	5l1fD-2ogsA: 21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L6E_A_SAMA601_0 (N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT)	2rci	TYPE-2BA CYTOLYTIC DELTA-ENDOTOXIN (Bacillus thuringiensis)	5 / 12	ILE A  83 PRO A 188 LEU A 220 PHE A  64 GLY A  66	ILE  A  83 ( 0.7A) PRO  A 188 ( 1.1A) LEU  A 220 ( 0.6A) PHE  A  64 ( 1.3A) GLY  A  66 ( 0.0A)	0.92A	5l6eA-2rciA: undetectable	5l6eA-2rciA: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L8D_B_ACTB601_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	3r9r	PHOSPHORIBOSYLAMINOI MIDAZOLE-SUCCINOCARB OXAMIDE SYNTHASE (Mycobacteroides abscessus)	3 / 3	THR A 181 PRO A 138 ASP A 136	THR  A 181 ( 0.8A) PRO  A 138 ( 1.1A) ASP  A 136 ( 0.6A)	0.91A	5l8dB-3r9rA: undetectable	5l8dB-3r9rA: 21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M45_A_ACTA803_0 (ACETONE CARBOXYLASE ALPHA SUBUNIT)	1zlm	OSTEOCLAST STIMULATING FACTOR 1 (Homo sapiens)	4 / 4	GLU A  30 PRO A  62 ILE A  61 LEU A  60	GLU  A  30 ( 0.6A) PRO  A  62 ( 1.1A) ILE  A  61 ( 0.5A) LEU  A  60 ( 0.6A)	1.17A	5m45A-1zlmA: undetectable	5m45A-1zlmA: 6.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M45_D_ACTD803_0 (ACETONE CARBOXYLASE ALPHA SUBUNIT)	1zlm	OSTEOCLAST STIMULATING FACTOR 1 (Homo sapiens)	4 / 4	GLU A  30 PRO A  62 ILE A  61 LEU A  60	GLU  A  30 ( 0.6A) PRO  A  62 ( 1.1A) ILE  A  61 ( 0.5A) LEU  A  60 ( 0.6A)	1.21A	5m45D-1zlmA: undetectable	5m45D-1zlmA: 6.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M45_G_ACTG803_0 (ACETONE CARBOXYLASE ALPHA SUBUNIT)	1zlm	OSTEOCLAST STIMULATING FACTOR 1 (Homo sapiens)	4 / 4	GLU A  30 PRO A  62 ILE A  61 LEU A  60	GLU  A  30 ( 0.6A) PRO  A  62 ( 1.1A) ILE  A  61 ( 0.5A) LEU  A  60 ( 0.6A)	1.15A	5m45G-1zlmA: undetectable	5m45G-1zlmA: 6.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M45_J_ACTJ803_0 (ACETONE CARBOXYLASE ALPHA SUBUNIT)	1zlm	OSTEOCLAST STIMULATING FACTOR 1 (Homo sapiens)	4 / 4	GLU A  30 PRO A  62 ILE A  61 LEU A  60	GLU  A  30 ( 0.6A) PRO  A  62 ( 1.1A) ILE  A  61 ( 0.5A) LEU  A  60 ( 0.6A)	1.20A	5m45J-1zlmA: undetectable	5m45J-1zlmA: 6.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MUR_B_PFLB407_1 (PROTON-GATED ION CHANNEL)	4cgu	PROTEIN INTERACTING WITH HSP90 1 (Saccharomyces cerevisiae)	4 / 7	PRO B 299 ILE B 329 ILE B 342 ILE B 316	PRO  B 299 ( 1.1A) ILE  B 329 ( 0.7A) ILE  B 342 ( 0.6A) ILE  B 316 ( 0.7A)	0.94A	5murB-4cguB: undetectable	5murB-4cguB: 19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWU_B_ACTB601_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	3r9r	PHOSPHORIBOSYLAMINOI MIDAZOLE-SUCCINOCARB OXAMIDE SYNTHASE (Mycobacteroides abscessus)	3 / 3	THR A 181 PRO A 138 ASP A 136	THR  A 181 ( 0.8A) PRO  A 138 ( 1.1A) ASP  A 136 ( 0.6A)	0.91A	5mwuB-3r9rA: undetectable	5mwuB-3r9rA: 21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MZR_A_PFLA412_1 (PROTON-GATED ION CHANNEL)	5wpi	HSVA (Erwinia amylovora)	5 / 10	PRO A 273 ILE A 212 MET A 207 VAL A 262 ILE A 366	PRO  A 273 ( 1.1A) ILE  A 212 ( 0.6A) MET  A 207 ( 0.0A) VAL  A 262 ( 0.6A) ILE  A 366 ( 0.7A)	1.40A	5mzrA-5wpiA: undetectable	5mzrA-5wpiA: 14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MZR_C_PFLC409_1 (PROTON-GATED ION CHANNEL)	5wpi	HSVA (Erwinia amylovora)	5 / 10	PRO A 273 ILE A 212 MET A 207 VAL A 262 ILE A 366	PRO  A 273 ( 1.1A) ILE  A 212 ( 0.6A) MET  A 207 ( 0.0A) VAL  A 262 ( 0.6A) ILE  A 366 ( 0.7A)	1.40A	5mzrC-5wpiA: undetectable	5mzrC-5wpiA: 14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MZR_D_PFLD410_1 (PROTON-GATED ION CHANNEL)	5wpi	HSVA (Erwinia amylovora)	5 / 9	PRO A 273 ILE A 212 MET A 207 VAL A 262 ILE A 366	PRO  A 273 ( 1.1A) ILE  A 212 ( 0.6A) MET  A 207 ( 0.0A) VAL  A 262 ( 0.6A) ILE  A 366 ( 0.7A)	1.42A	5mzrD-5wpiA: undetectable	5mzrD-5wpiA: 14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NFJ_B_SAMB501_0 (MITOCHONDRIAL RIBONUCLEASE P PROTEIN 1)	3cmm	UBIQUITIN-ACTIVATING ENZYME E1 1 (Saccharomyces cerevisiae)	5 / 12	LEU A 347 ILE A 348 ASP A 316 LEU A 394 LEU A 397	None None PRO  A5119 (-3.7A) None None	1.02A	5nfjB-3cmmA: 2.5	5nfjB-3cmmA: 11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NFJ_C_SAMC501_0 (MITOCHONDRIAL RIBONUCLEASE P PROTEIN 1)	3cmm	UBIQUITIN-ACTIVATING ENZYME E1 1 (Saccharomyces cerevisiae)	5 / 12	LEU A 347 ILE A 348 ASP A 316 LEU A 394 LEU A 397	None None PRO  A5119 (-3.7A) None None	1.02A	5nfjC-3cmmA: 2.9	5nfjC-3cmmA: 11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NY7_A_NCAA303_0 (AMIDASE)	3r64	NAD DEPENDENT BENZALDEHYDE DEHYDROGENASE (Corynebacterium glutamicum)	4 / 6	GLY A 334 PRO A 335 THR A 103 SER A 327	GLY  A 334 ( 0.0A) PRO  A 335 ( 1.1A) THR  A 103 ( 0.8A) SER  A 327 ( 0.0A)	1.13A	5ny7A-3r64A: undetectable	5ny7A-3r64A: 22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5O96_A_SAMA501_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE E)	1ryn	PROTEIN CRS2 (Zea mays)	5 / 11	LEU A 105 PRO A 131 LEU A 133 THR A 175 ALA A 172	LEU  A 105 ( 0.6A) PRO  A 131 ( 1.1A) LEU  A 133 ( 0.6A) THR  A 175 ( 0.8A) ALA  A 172 ( 0.0A)	1.06A	5o96A-1rynA: undetectable 5o96B-1rynA: 2.1	5o96A-1rynA: 22.13 5o96B-1rynA: 22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OG9_A_TESA503_1 (-)	5cdn	DNA GYRASE SUBUNIT A (Staphylococcus aureus)	5 / 9	LEU A 209 VAL A 195 LEU A 198 ILE A 346 PRO A 165	LEU  A 209 ( 0.6A) VAL  A 195 ( 0.6A) LEU  A 198 ( 0.6A) ILE  A 346 ( 0.6A) PRO  A 165 ( 1.1A)	1.38A	5og9A-5cdnA: 3.6	5og9A-5cdnA: 21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5PBE_A_TYLA2001_1 (BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B)	4jbe	GAMMA-GLUTAMYL PHOSPHATE REDUCTASE (Saccharomonospor a viridis)	4 / 6	PRO A 129 VAL A 133 VAL A 165 ILE A  75	PRO  A 129 ( 1.1A) VAL  A 133 ( 0.6A) VAL  A 165 ( 0.6A) ILE  A  75 ( 0.7A)	0.91A	5pbeA-4jbeA: undetectable	5pbeA-4jbeA: 18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TIW_B_OAQB302_0 (SULFOTRANSFERASE)	3i4k	MUCONATE LACTONIZING ENZYME (Corynebacterium glutamicum)	5 / 12	PRO A 177 ILE A 199 ASP A 180 ILE A 240 THR A 244	PRO  A 177 ( 1.1A) ILE  A 199 ( 0.4A) ASP  A 180 ( 0.5A) ILE  A 240 ( 0.6A) THR  A 244 ( 0.8A)	1.27A	5tiwB-3i4kA: undetectable	5tiwB-3i4kA: 23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UMD_A_YMZA3801_1 (60S RIBOSOMAL PROTEIN L28 28S RIBOSOMAL RNA 60S RIBOSOMAL PROTEIN L4)	4ki5	MURINE MONOCLONAL G99 FAB HEAVY CHAIN (Mus musculus)	4 / 6	ASN E  77 ALA E  24 PRO E  53 TYR E  27	ASN  E  77 ( 0.6A) ALA  E  24 ( 0.0A) PRO  E  53 ( 1.1A) TYR  E  27 ( 1.3A)	1.05A	5umd2-4ki5E: undetectable 5umdF-4ki5E: undetectable	5umd2-4ki5E: 17.39 5umdF-4ki5E: 16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_A_PCFA1805_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	2ogs	THERMOSTABLE CARBOXYLESTERASE EST50 (Geobacillus stearothermophil us)	4 / 7	VAL A 279 HIS A 287 PRO A 288 ILE A 289	VAL  A 279 ( 0.6A) HIS  A 287 ( 1.0A) PRO  A 288 ( 1.1A) ILE  A 289 ( 0.7A)	1.01A	5vkqA-2ogsA: undetectable 5vkqD-2ogsA: undetectable	5vkqA-2ogsA: 14.51 5vkqD-2ogsA: 14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_B_PCFB1802_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	6gef	TYPE IV SECRETION SYSTEM PROTEIN DOTB (Yersinia pseudotuberculos is)	4 / 7	SER A 181 THR A 178 PRO A 140 ILE A 139	SER  A 181 ( 0.0A) THR  A 178 ( 0.8A) PRO  A 140 ( 1.1A) ILE  A 139 ( 0.7A)	1.23A	5vkqA-6gefA: undetectable 5vkqB-6gefA: undetectable	5vkqA-6gefA: undetectable 5vkqB-6gefA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_D_PCFD1803_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	6gef	TYPE IV SECRETION SYSTEM PROTEIN DOTB (Yersinia pseudotuberculos is)	4 / 7	SER A 181 THR A 178 PRO A 140 ILE A 139	SER  A 181 ( 0.0A) THR  A 178 ( 0.8A) PRO  A 140 ( 1.1A) ILE  A 139 ( 0.7A)	1.22A	5vkqC-6gefA: undetectable 5vkqD-6gefA: undetectable	5vkqC-6gefA: undetectable 5vkqD-6gefA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WWS_B_SAMB501_0 (PUTATIVE METHYLTRANSFERASE NSUN6)	1txu	RAB5 GDP/GTP EXCHANGE FACTOR (Homo sapiens)	5 / 12	PRO A 329 ASP A 235 LYS A 234 ILE A 238 ASP A 230	PRO  A 329 ( 1.1A) ASP  A 235 ( 0.5A) LYS  A 234 ( 0.0A) ILE  A 238 ( 0.4A) ASP  A 230 ( 0.6A)	0.94A	5wwsB-1txuA: undetectable	5wwsB-1txuA: 18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1F_P_CHDP305_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	5mc5	XAA-PRO DIPEPTIDASE (Homo sapiens)	4 / 7	HIS A 377 ASP A 453 THR A 410 HIS A 255	GLY  A 503 ( 3.9A) None MN  A 499 ( 4.0A) PRO  A 504 (-4.2A)	1.34A	5x1fN-5mc5A: undetectable 5x1fP-5mc5A: 1.9	5x1fN-5mc5A: undetectable 5x1fP-5mc5A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X23_A_LSNA504_1 (CYTOCHROME P450 2C9)	2qc5	STREPTOGRAMIN B LACTONASE (Staphylococcus cohnii)	4 / 8	PHE A 198 ILE A 230 PRO A 221 PRO A 227	PHE  A 198 ( 1.3A) ILE  A 230 ( 0.6A) PRO  A 221 ( 1.1A) PRO  A 227 ( 1.1A)	1.08A	5x23A-2qc5A: undetectable	5x23A-2qc5A: 20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X2S_I_PEMI202_1 (HEMOGLOBIN SUBUNIT ALPHA HEMOGLOBIN SUBUNIT BETA)	4dlk	PHOSPHORIBOSYLAMINOI MIDAZOLE CARBOXYLASE, ATPASE SUBUNIT (Bacillus anthracis)	4 / 8	PRO A 207 LYS A 204 THR A 286 TYR A 279	PRO  A 207 ( 1.1A) LYS  A 204 ( 0.0A) THR  A 286 ( 0.8A) TYR  A 279 ( 1.3A)	1.36A	5x2sI-4dlkA: undetectable 5x2sJ-4dlkA: undetectable 5x2sK-4dlkA: undetectable	5x2sI-4dlkA: 17.77 5x2sJ-4dlkA: 19.82 5x2sK-4dlkA: 17.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIO_A_HFGA801_0 (PROLINE-TRNA SYNTHETASE CLASS II AARS (YBAK RNA BINDING DOMAIN PLUS TRNA SYNTHETASE))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	9 / 12	GLU A1154 PRO A1120 ARG A1152 TRP A1169 GLU A1171 HIS A1173 THR A1240 SER A1272 GLY A1274	91Y  A1601 (-4.6A) None PRO  A1602 ( 3.4A) None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.88A	5xioA-5vadA: 48.3	5xioA-5vadA: 54.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIO_A_HFGA801_0 (PROLINE-TRNA SYNTHETASE CLASS II AARS (YBAK RNA BINDING DOMAIN PLUS TRNA SYNTHETASE))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	8 / 12	GLU A1154 PRO A1120 GLU A1171 HIS A1173 PHE A1216 THR A1240 SER A1272 GLY A1274	91Y  A1601 (-4.6A) None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) PRO  A1602 (-4.3A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.96A	5xioA-5vadA: 48.3	5xioA-5vadA: 54.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIO_A_HFGA801_0 (PROLINE-TRNA SYNTHETASE CLASS II AARS (YBAK RNA BINDING DOMAIN PLUS TRNA SYNTHETASE))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	6 / 12	VAL A1101 PRO A1120 ARG A1152 HIS A1173 THR A1222 SER A1272	None None PRO  A1602 ( 3.4A) PRO  A1602 ( 4.5A) None PRO  A1602 (-3.3A)	1.42A	5xioA-5vadA: 48.3	5xioA-5vadA: 54.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIO_A_HFGA801_0 (PROLINE-TRNA SYNTHETASE CLASS II AARS (YBAK RNA BINDING DOMAIN PLUS TRNA SYNTHETASE))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	9 / 12	VAL A1101 PRO A1120 ARG A1152 TRP A1169 GLU A1171 HIS A1173 THR A1240 SER A1272 GLY A1274	None None PRO  A1602 ( 3.4A) None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.60A	5xioA-5vadA: 48.3	5xioA-5vadA: 54.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIO_A_HFGA801_0 (PROLINE-TRNA SYNTHETASE CLASS II AARS (YBAK RNA BINDING DOMAIN PLUS TRNA SYNTHETASE))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	8 / 12	VAL A1101 PRO A1120 GLU A1171 HIS A1173 PHE A1216 THR A1240 SER A1272 GLY A1274	None None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) PRO  A1602 (-4.3A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.79A	5xioA-5vadA: 48.3	5xioA-5vadA: 54.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIO_A_HFGA801_1 (PROLINE-TRNA SYNTHETASE CLASS II AARS (YBAK RNA BINDING DOMAIN PLUS TRNA SYNTHETASE))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	3 / 3	THR A1121 GLU A1123 HIS A1242	PRO  A1602 (-3.5A) PRO  A1602 (-2.8A) PRO  A1602 (-4.1A)	0.51A	5xioA-5vadA: 48.3	5xioA-5vadA: 54.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIO_B_HFGB802_0 (PROLINE-TRNA SYNTHETASE CLASS II AARS (YBAK RNA BINDING DOMAIN PLUS TRNA SYNTHETASE))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	6 / 12	GLU A1100 VAL A1101 ARG A1152 TRP A1169 GLU A1171 THR A1240	None None PRO  A1602 ( 3.4A) None PRO  A1602 ( 4.7A) 91Y  A1601 (-4.2A)	0.82A	5xioB-5vadA: 48.5	5xioB-5vadA: 54.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIO_B_HFGB802_0 (PROLINE-TRNA SYNTHETASE CLASS II AARS (YBAK RNA BINDING DOMAIN PLUS TRNA SYNTHETASE))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	9 / 12	GLU A1154 PRO A1120 THR A1121 ARG A1152 TRP A1169 GLU A1171 HIS A1173 THR A1240 HIS A1242	91Y  A1601 (-4.6A) None PRO  A1602 (-3.5A) PRO  A1602 ( 3.4A) None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) 91Y  A1601 (-4.2A) PRO  A1602 (-4.1A)	0.75A	5xioB-5vadA: 48.5	5xioB-5vadA: 54.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIO_B_HFGB802_0 (PROLINE-TRNA SYNTHETASE CLASS II AARS (YBAK RNA BINDING DOMAIN PLUS TRNA SYNTHETASE))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	7 / 12	GLU A1154 THR A1121 GLU A1171 HIS A1173 PHE A1216 THR A1240 HIS A1242	91Y  A1601 (-4.6A) PRO  A1602 (-3.5A) PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) PRO  A1602 (-4.3A) 91Y  A1601 (-4.2A) PRO  A1602 (-4.1A)	0.84A	5xioB-5vadA: 48.5	5xioB-5vadA: 54.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIO_B_HFGB802_0 (PROLINE-TRNA SYNTHETASE CLASS II AARS (YBAK RNA BINDING DOMAIN PLUS TRNA SYNTHETASE))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	5 / 12	PHE A1097 GLU A1154 PHE A1216 THR A1240 HIS A1242	None 91Y  A1601 (-4.6A) PRO  A1602 (-4.3A) 91Y  A1601 (-4.2A) PRO  A1602 (-4.1A)	1.34A	5xioB-5vadA: 48.5	5xioB-5vadA: 54.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIO_B_HFGB802_0 (PROLINE-TRNA SYNTHETASE CLASS II AARS (YBAK RNA BINDING DOMAIN PLUS TRNA SYNTHETASE))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	5 / 12	PHE A1097 VAL A1101 PHE A1216 THR A1240 HIS A1242	None None PRO  A1602 (-4.3A) 91Y  A1601 (-4.2A) PRO  A1602 (-4.1A)	1.38A	5xioB-5vadA: 48.5	5xioB-5vadA: 54.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIO_B_HFGB802_0 (PROLINE-TRNA SYNTHETASE CLASS II AARS (YBAK RNA BINDING DOMAIN PLUS TRNA SYNTHETASE))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	9 / 12	VAL A1101 PRO A1120 THR A1121 ARG A1152 TRP A1169 GLU A1171 HIS A1173 THR A1240 HIS A1242	None None PRO  A1602 (-3.5A) PRO  A1602 ( 3.4A) None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) 91Y  A1601 (-4.2A) PRO  A1602 (-4.1A)	0.59A	5xioB-5vadA: 48.5	5xioB-5vadA: 54.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIO_B_HFGB802_0 (PROLINE-TRNA SYNTHETASE CLASS II AARS (YBAK RNA BINDING DOMAIN PLUS TRNA SYNTHETASE))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	5 / 12	VAL A1101 PRO A1120 THR A1121 GLU A1171 PHE A1248	None None PRO  A1602 (-3.5A) PRO  A1602 ( 4.7A) None	1.29A	5xioB-5vadA: 48.5	5xioB-5vadA: 54.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIO_B_HFGB802_0 (PROLINE-TRNA SYNTHETASE CLASS II AARS (YBAK RNA BINDING DOMAIN PLUS TRNA SYNTHETASE))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	7 / 12	VAL A1101 THR A1121 GLU A1171 HIS A1173 PHE A1216 THR A1240 HIS A1242	None PRO  A1602 (-3.5A) PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) PRO  A1602 (-4.3A) 91Y  A1601 (-4.2A) PRO  A1602 (-4.1A)	0.70A	5xioB-5vadA: 48.5	5xioB-5vadA: 54.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIP_A_HFGA1003_0 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	5 / 12	GLU A1154 PHE A1216 THR A1240 SER A1272 GLY A1274	91Y  A1601 (-4.6A) PRO  A1602 (-4.3A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.71A	5xipA-5vadA: 49.0	5xipA-5vadA: 55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIP_A_HFGA1003_0 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	9 / 12	LEU A1087 GLU A1100 PRO A1120 THR A1121 ARG A1152 HIS A1173 THR A1240 SER A1272 GLY A1274	None None None PRO  A1602 (-3.5A) PRO  A1602 ( 3.4A) PRO  A1602 ( 4.5A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.74A	5xipA-5vadA: 49.0	5xipA-5vadA: 55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIP_A_HFGA1003_0 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	6 / 12	LEU A1087 GLU A1100 VAL A1101 PRO A1120 HIS A1173 THR A1222	None None None None PRO  A1602 ( 4.5A) None	1.48A	5xipA-5vadA: 49.0	5xipA-5vadA: 55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIP_A_HFGA1003_0 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	9 / 12	LEU A1087 GLU A1100 VAL A1101 PRO A1120 THR A1121 ARG A1152 HIS A1173 THR A1240 GLY A1274	None None None None PRO  A1602 (-3.5A) PRO  A1602 ( 3.4A) PRO  A1602 ( 4.5A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.7A)	0.71A	5xipA-5vadA: 49.0	5xipA-5vadA: 55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIP_A_HFGA1003_0 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	8 / 12	LEU A1087 PRO A1120 THR A1121 HIS A1173 PHE A1216 THR A1240 SER A1272 GLY A1274	None None PRO  A1602 (-3.5A) PRO  A1602 ( 4.5A) PRO  A1602 (-4.3A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.72A	5xipA-5vadA: 49.0	5xipA-5vadA: 55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIP_A_HFGA1003_0 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	5 / 12	VAL A1101 PRO A1120 THR A1121 HIS A1173 PHE A1248	None None PRO  A1602 (-3.5A) PRO  A1602 ( 4.5A) None	1.25A	5xipA-5vadA: 49.0	5xipA-5vadA: 55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIP_A_HFGA1003_1 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	3 / 3	GLU A1123 TRP A1169 HIS A1242	PRO  A1602 (-2.8A) None PRO  A1602 (-4.1A)	0.42A	5xipA-5vadA: 49.0	5xipA-5vadA: 55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIP_B_HFGB1003_0 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	9 / 12	GLU A1100 VAL A1101 PRO A1120 THR A1121 GLU A1123 ARG A1152 TRP A1169 HIS A1173 THR A1240	None None None PRO  A1602 (-3.5A) PRO  A1602 (-2.8A) PRO  A1602 ( 3.4A) None PRO  A1602 ( 4.5A) 91Y  A1601 (-4.2A)	0.67A	5xipB-5vadA: 48.9	5xipB-5vadA: 55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIP_B_HFGB1003_0 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	7 / 12	GLU A1100 VAL A1101 PRO A1120 THR A1121 GLU A1123 HIS A1173 THR A1222	None None None PRO  A1602 (-3.5A) PRO  A1602 (-2.8A) PRO  A1602 ( 4.5A) None	1.10A	5xipB-5vadA: 48.9	5xipB-5vadA: 55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIP_B_HFGB1003_0 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	7 / 12	GLU A1154 THR A1121 ARG A1152 TRP A1169 HIS A1173 THR A1240 HIS A1242	91Y  A1601 (-4.6A) PRO  A1602 (-3.5A) PRO  A1602 ( 3.4A) None PRO  A1602 ( 4.5A) 91Y  A1601 (-4.2A) PRO  A1602 (-4.1A)	0.91A	5xipB-5vadA: 48.9	5xipB-5vadA: 55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIP_B_HFGB1003_0 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	6 / 12	GLU A1154 TRP A1169 HIS A1173 PHE A1216 THR A1240 HIS A1242	91Y  A1601 (-4.6A) None PRO  A1602 ( 4.5A) PRO  A1602 (-4.3A) 91Y  A1601 (-4.2A) PRO  A1602 (-4.1A)	0.91A	5xipB-5vadA: 48.9	5xipB-5vadA: 55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIP_B_HFGB1003_0 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	7 / 12	PRO A1120 GLU A1123 TRP A1169 HIS A1173 PHE A1216 THR A1240 HIS A1242	None PRO  A1602 (-2.8A) None PRO  A1602 ( 4.5A) PRO  A1602 (-4.3A) 91Y  A1601 (-4.2A) PRO  A1602 (-4.1A)	0.64A	5xipB-5vadA: 48.9	5xipB-5vadA: 55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIP_B_HFGB1003_0 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	9 / 12	VAL A1101 PRO A1120 THR A1121 GLU A1123 ARG A1152 TRP A1169 HIS A1173 THR A1240 HIS A1242	None None PRO  A1602 (-3.5A) PRO  A1602 (-2.8A) PRO  A1602 ( 3.4A) None PRO  A1602 ( 4.5A) 91Y  A1601 (-4.2A) PRO  A1602 (-4.1A)	0.58A	5xipB-5vadA: 48.9	5xipB-5vadA: 55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIP_B_HFGB1003_0 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	5 / 12	VAL A1101 PRO A1120 THR A1121 HIS A1173 PHE A1248	None None PRO  A1602 (-3.5A) PRO  A1602 ( 4.5A) None	1.24A	5xipB-5vadA: 48.9	5xipB-5vadA: 55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIP_C_HFGC1003_0 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	7 / 12	LEU A1087 GLU A1100 VAL A1101 PRO A1120 GLU A1123 HIS A1173 THR A1222	None None None None PRO  A1602 (-2.8A) PRO  A1602 ( 4.5A) None	1.40A	5xipC-5vadA: 48.7	5xipC-5vadA: 55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIP_C_HFGC1003_0 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	11 / 12	LEU A1087 GLU A1100 VAL A1101 PRO A1120 THR A1121 GLU A1123 TRP A1169 GLU A1171 HIS A1173 THR A1240 GLY A1274	None None None None PRO  A1602 (-3.5A) PRO  A1602 (-2.8A) None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.7A)	0.64A	5xipC-5vadA: 48.7	5xipC-5vadA: 55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIP_C_HFGC1003_0 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	11 / 12	LEU A1087 VAL A1101 PRO A1120 THR A1121 GLU A1123 TRP A1169 GLU A1171 HIS A1173 PHE A1216 THR A1240 GLY A1274	None None None PRO  A1602 (-3.5A) PRO  A1602 (-2.8A) None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) PRO  A1602 (-4.3A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.7A)	0.63A	5xipC-5vadA: 48.7	5xipC-5vadA: 55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIP_C_HFGC1003_0 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	5 / 12	VAL A1101 PRO A1120 THR A1121 GLU A1171 PHE A1248	None None PRO  A1602 (-3.5A) PRO  A1602 ( 4.7A) None	1.23A	5xipC-5vadA: 48.7	5xipC-5vadA: 55.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XIP_D_HFGD1003_0 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	2nvv	ACETYL-COA HYDROLASE/TRANSFERAS E FAMILY PROTEIN (Porphyromonas gingivalis)	5 / 12	LEU A 145 VAL A 199 PRO A 138 THR A 139 GLU A 126	LEU  A 145 ( 0.6A) VAL  A 199 ( 0.6A) PRO  A 138 ( 1.1A) THR  A 139 ( 0.8A) GLU  A 126 ( 0.5A)	1.39A	5xipD-2nvvA: undetectable	5xipD-2nvvA: 21.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIP_D_HFGD1003_0 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	11 / 12	LEU A1087 GLU A1100 VAL A1101 PRO A1120 THR A1121 GLU A1123 ARG A1152 TRP A1169 GLU A1171 THR A1240 TRP A1273	None None None None PRO  A1602 (-3.5A) PRO  A1602 (-2.8A) PRO  A1602 ( 3.4A) None PRO  A1602 ( 4.7A) 91Y  A1601 (-4.2A) None	0.73A	5xipD-5vadA: 48.5	5xipD-5vadA: 55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIP_D_HFGD1003_0 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	7 / 12	LEU A1087 GLU A1100 VAL A1101 PRO A1120 THR A1121 GLU A1123 THR A1222	None None None None PRO  A1602 (-3.5A) PRO  A1602 (-2.8A) None	1.36A	5xipD-5vadA: 48.5	5xipD-5vadA: 55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIP_D_HFGD1003_0 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	10 / 12	LEU A1087 VAL A1101 PRO A1120 GLU A1123 ARG A1152 TRP A1169 GLU A1171 PHE A1216 THR A1240 TRP A1273	None None None PRO  A1602 (-2.8A) PRO  A1602 ( 3.4A) None PRO  A1602 ( 4.7A) PRO  A1602 (-4.3A) 91Y  A1601 (-4.2A) None	0.71A	5xipD-5vadA: 48.5	5xipD-5vadA: 55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIP_D_HFGD1003_0 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	6 / 12	VAL A1101 PRO A1120 THR A1121 GLU A1171 PHE A1248 TRP A1273	None None PRO  A1602 (-3.5A) PRO  A1602 ( 4.7A) None None	1.42A	5xipD-5vadA: 48.5	5xipD-5vadA: 55.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIQ_A_HFGA1002_0 (PROLYL-TRNA SYNTHETASE (PRORS))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	5 / 12	GLU A1154 PHE A1216 THR A1240 SER A1272 GLY A1274	91Y  A1601 (-4.6A) PRO  A1602 (-4.3A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.84A	5xiqA-5vadA: 49.7	5xiqA-5vadA: 55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIQ_A_HFGA1002_0 (PROLYL-TRNA SYNTHETASE (PRORS))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	8 / 12	LEU A1087 GLU A1100 VAL A1101 TRP A1169 GLU A1171 HIS A1173 THR A1240 GLY A1274	None None None None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.7A)	0.74A	5xiqA-5vadA: 49.7	5xiqA-5vadA: 55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIQ_A_HFGA1002_0 (PROLYL-TRNA SYNTHETASE (PRORS))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	9 / 12	LEU A1087 VAL A1101 PRO A1120 TRP A1169 GLU A1171 HIS A1173 THR A1240 SER A1272 GLY A1274	None None None None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.58A	5xiqA-5vadA: 49.7	5xiqA-5vadA: 55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIQ_A_HFGA1002_0 (PROLYL-TRNA SYNTHETASE (PRORS))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	9 / 12	LEU A1087 VAL A1101 TRP A1169 GLU A1171 HIS A1173 PHE A1216 THR A1240 SER A1272 GLY A1274	None None None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) PRO  A1602 (-4.3A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.3A) PRO  A1602 (-3.7A)	0.72A	5xiqA-5vadA: 49.7	5xiqA-5vadA: 55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIQ_A_HFGA1002_1 (PROLYL-TRNA SYNTHETASE (PRORS))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	4 / 4	THR A1121 GLU A1123 ARG A1152 HIS A1242	PRO  A1602 (-3.5A) PRO  A1602 (-2.8A) PRO  A1602 ( 3.4A) PRO  A1602 (-4.1A)	0.59A	5xiqA-5vadA: 49.7	5xiqA-5vadA: 55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIQ_B_HFGB1002_0 (PROLYL-TRNA SYNTHETASE (PRORS))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	8 / 12	LEU A1087 GLU A1100 VAL A1101 ARG A1152 TRP A1169 GLU A1171 HIS A1173 THR A1240	None None None PRO  A1602 ( 3.4A) None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) 91Y  A1601 (-4.2A)	0.78A	5xiqB-5vadA: 49.9	5xiqB-5vadA: 55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIQ_B_HFGB1002_0 (PROLYL-TRNA SYNTHETASE (PRORS))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	9 / 12	LEU A1087 VAL A1101 PRO A1120 ARG A1152 TRP A1169 GLU A1171 HIS A1173 THR A1240 SER A1272	None None None PRO  A1602 ( 3.4A) None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.3A)	0.59A	5xiqB-5vadA: 49.9	5xiqB-5vadA: 55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIQ_B_HFGB1002_0 (PROLYL-TRNA SYNTHETASE (PRORS))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	6 / 12	LEU A1087 VAL A1101 PRO A1120 HIS A1173 THR A1222 SER A1272	None None None PRO  A1602 ( 4.5A) None PRO  A1602 (-3.3A)	1.44A	5xiqB-5vadA: 49.9	5xiqB-5vadA: 55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIQ_B_HFGB1002_0 (PROLYL-TRNA SYNTHETASE (PRORS))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	9 / 12	LEU A1087 VAL A1101 PRO A1120 TRP A1169 GLU A1171 HIS A1173 PHE A1216 THR A1240 SER A1272	None None None None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) PRO  A1602 (-4.3A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.3A)	0.73A	5xiqB-5vadA: 49.9	5xiqB-5vadA: 55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIQ_B_HFGB1002_1 (PROLYL-TRNA SYNTHETASE (PRORS))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	3 / 3	THR A1121 GLU A1123 HIS A1242	PRO  A1602 (-3.5A) PRO  A1602 (-2.8A) PRO  A1602 (-4.1A)	0.48A	5xiqB-5vadA: 49.9	5xiqB-5vadA: 55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIQ_C_HFGC1002_0 (PROLYL-TRNA SYNTHETASE (PRORS))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	7 / 12	GLU A1100 VAL A1101 PRO A1120 THR A1121 ARG A1152 THR A1222 SER A1272	None None None PRO  A1602 (-3.5A) PRO  A1602 ( 3.4A) None PRO  A1602 (-3.3A)	1.41A	5xiqC-5vadA: 49.7	5xiqC-5vadA: 55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIQ_C_HFGC1002_0 (PROLYL-TRNA SYNTHETASE (PRORS))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	10 / 12	GLU A1100 VAL A1101 PRO A1120 THR A1121 ARG A1152 TRP A1169 GLU A1171 HIS A1173 THR A1240 SER A1272	None None None PRO  A1602 (-3.5A) PRO  A1602 ( 3.4A) None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.3A)	0.77A	5xiqC-5vadA: 49.7	5xiqC-5vadA: 55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIQ_C_HFGC1002_0 (PROLYL-TRNA SYNTHETASE (PRORS))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	10 / 12	GLU A1100 VAL A1101 PRO A1120 THR A1121 TRP A1169 GLU A1171 HIS A1173 PHE A1216 THR A1240 SER A1272	None None None PRO  A1602 (-3.5A) None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) PRO  A1602 (-4.3A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.3A)	0.88A	5xiqC-5vadA: 49.7	5xiqC-5vadA: 55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIQ_D_HFGD1002_0 (PROLYL-TRNA SYNTHETASE (PRORS))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	10 / 12	LEU A1087 GLU A1100 VAL A1101 PRO A1120 ARG A1152 TRP A1169 GLU A1171 HIS A1173 THR A1240 GLY A1274	None None None None PRO  A1602 ( 3.4A) None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.7A)	0.76A	5xiqD-5vadA: 49.6	5xiqD-5vadA: 55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIQ_D_HFGD1002_0 (PROLYL-TRNA SYNTHETASE (PRORS))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	10 / 12	LEU A1087 GLU A1100 VAL A1101 PRO A1120 TRP A1169 GLU A1171 HIS A1173 PHE A1216 THR A1240 GLY A1274	None None None None None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) PRO  A1602 (-4.3A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.7A)	0.90A	5xiqD-5vadA: 49.6	5xiqD-5vadA: 55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIQ_D_HFGD1002_0 (PROLYL-TRNA SYNTHETASE (PRORS))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	5 / 12	VAL A1101 PRO A1120 GLU A1171 HIS A1173 PHE A1248	None None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) None	1.33A	5xiqD-5vadA: 49.6	5xiqD-5vadA: 55.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5XIQ_D_HFGD1002_1 (PROLYL-TRNA SYNTHETASE (PRORS))	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	3 / 3	THR A1121 GLU A1123 HIS A1242	PRO  A1602 (-3.5A) PRO  A1602 (-2.8A) PRO  A1602 (-4.1A)	0.52A	5xiqD-5vadA: 49.6	5xiqD-5vadA: 55.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z0F_B_DAHB98_0 (MELC TYROSINASE)	3ulk	KETOL-ACID REDUCTOISOMERASE (Escherichia coli)	5 / 11	ASN A 181 HIS A 178 VAL A 177 ASP A 182 PRO A 183	ASN  A 181 ( 0.6A) HIS  A 178 ( 1.0A) VAL  A 177 ( 0.6A) ASP  A 182 ( 0.6A) PRO  A 183 ( 1.1A)	1.04A	5z0fA-3ulkA: undetectable 5z0fB-3ulkA: undetectable	5z0fA-3ulkA: 10.71 5z0fB-3ulkA: 10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z0G_B_DAHB98_0 (MELC TYROSINASE)	3ulk	KETOL-ACID REDUCTOISOMERASE (Escherichia coli)	5 / 11	ASN A 181 HIS A 178 VAL A 177 ASP A 182 PRO A 183	ASN  A 181 ( 0.6A) HIS  A 178 ( 1.0A) VAL  A 177 ( 0.6A) ASP  A 182 ( 0.6A) PRO  A 183 ( 1.1A)	0.97A	5z0gA-3ulkA: undetectable 5z0gB-3ulkA: undetectable	5z0gA-3ulkA: 10.71 5z0gB-3ulkA: 10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z0H_B_DAHB98_0 (MELC TYROSINASE)	3ulk	KETOL-ACID REDUCTOISOMERASE (Escherichia coli)	5 / 11	ASN A 181 HIS A 178 VAL A 177 ASP A 182 PRO A 183	ASN  A 181 ( 0.6A) HIS  A 178 ( 1.0A) VAL  A 177 ( 0.6A) ASP  A 182 ( 0.6A) PRO  A 183 ( 1.1A)	0.95A	5z0hA-3ulkA: undetectable 5z0hB-3ulkA: undetectable	5z0hA-3ulkA: 10.71 5z0hB-3ulkA: 10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z0I_B_DAHB98_0 (MELC TYROSINASE)	3ulk	KETOL-ACID REDUCTOISOMERASE (Escherichia coli)	5 / 11	ASN A 181 HIS A 178 VAL A 177 ASP A 182 PRO A 183	ASN  A 181 ( 0.6A) HIS  A 178 ( 1.0A) VAL  A 177 ( 0.6A) ASP  A 182 ( 0.6A) PRO  A 183 ( 1.1A)	0.97A	5z0iA-3ulkA: undetectable 5z0iB-3ulkA: undetectable	5z0iA-3ulkA: 10.71 5z0iB-3ulkA: 10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z0J_B_DAHB98_0 (MELC TYROSINASE)	3ulk	KETOL-ACID REDUCTOISOMERASE (Escherichia coli)	5 / 11	ASN A 181 HIS A 178 VAL A 177 ASP A 182 PRO A 183	ASN  A 181 ( 0.6A) HIS  A 178 ( 1.0A) VAL  A 177 ( 0.6A) ASP  A 182 ( 0.6A) PRO  A 183 ( 1.1A)	0.97A	5z0jA-3ulkA: undetectable 5z0jB-3ulkA: undetectable	5z0jA-3ulkA: 10.71 5z0jB-3ulkA: 10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z0K_B_DAHB98_0 (MELC TYROSINASE)	3ulk	KETOL-ACID REDUCTOISOMERASE (Escherichia coli)	5 / 11	ASN A 181 HIS A 178 VAL A 177 ASP A 182 PRO A 183	ASN  A 181 ( 0.6A) HIS  A 178 ( 1.0A) VAL  A 177 ( 0.6A) ASP  A 182 ( 0.6A) PRO  A 183 ( 1.1A)	0.97A	5z0kA-3ulkA: undetectable 5z0kB-3ulkA: undetectable	5z0kA-3ulkA: 10.71 5z0kB-3ulkA: 10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z0L_B_DAHB98_0 (MELC TYROSINASE)	3ulk	KETOL-ACID REDUCTOISOMERASE (Escherichia coli)	5 / 11	ASN A 181 HIS A 178 VAL A 177 ASP A 182 PRO A 183	ASN  A 181 ( 0.6A) HIS  A 178 ( 1.0A) VAL  A 177 ( 0.6A) ASP  A 182 ( 0.6A) PRO  A 183 ( 1.1A)	0.96A	5z0lA-3ulkA: undetectable 5z0lB-3ulkA: undetectable	5z0lA-3ulkA: 10.71 5z0lB-3ulkA: 10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z0M_B_DAHB98_0 (MELC TYROSINASE)	3ulk	KETOL-ACID REDUCTOISOMERASE (Escherichia coli)	5 / 11	ASN A 181 HIS A 178 VAL A 177 ASP A 182 PRO A 183	ASN  A 181 ( 0.6A) HIS  A 178 ( 1.0A) VAL  A 177 ( 0.6A) ASP  A 182 ( 0.6A) PRO  A 183 ( 1.1A)	0.97A	5z0mA-3ulkA: undetectable 5z0mB-3ulkA: undetectable	5z0mA-3ulkA: 10.71 5z0mB-3ulkA: 10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z6L_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	1txu	RAB5 GDP/GTP EXCHANGE FACTOR (Homo sapiens)	5 / 9	ILE A 242 ALA A 244 MET A 385 LEU A 369 PRO A 317	ILE  A 242 ( 0.7A) ALA  A 244 ( 0.0A) TRP  A 247 ( 3.6A) LEU  A 369 ( 0.6A) PRO  A 317 ( 1.1A)	1.36A	5z6lA-1txuA: undetectable	5z6lA-1txuA: 20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZVG_A_SAMA401_0 (389AA LONG HYPOTHETICAL NUCLEOLAR PROTEIN)	3r9r	PHOSPHORIBOSYLAMINOI MIDAZOLE-SUCCINOCARB OXAMIDE SYNTHASE (Mycobacteroides abscessus)	5 / 12	GLY A  -1 SER A   4 ALA A  87 ARG A  86 PRO A 295	GLY  A  -1 ( 0.0A) SER  A   4 ( 0.0A) ALA  A  87 ( 0.0A) ARG  A  86 ( 0.6A) PRO  A 295 ( 1.1A)	1.07A	5zvgA-3r9rA: undetectable	5zvgA-3r9rA: 21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZVG_B_SAMB401_0 (389AA LONG HYPOTHETICAL NUCLEOLAR PROTEIN)	3r9r	PHOSPHORIBOSYLAMINOI MIDAZOLE-SUCCINOCARB OXAMIDE SYNTHASE (Mycobacteroides abscessus)	5 / 12	GLY A  -1 SER A   4 ALA A  87 ARG A  86 PRO A 295	GLY  A  -1 ( 0.0A) SER  A   4 ( 0.0A) ALA  A  87 ( 0.0A) ARG  A  86 ( 0.6A) PRO  A 295 ( 1.1A)	1.05A	5zvgB-3r9rA: undetectable	5zvgB-3r9rA: 21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AK3_B_P2EB1201_1 (PROSTAGLANDIN E2 RECEPTOR EP3 SUBTYPE,SOLUBLE CYTOCHROME B562)	4mwt	LYSOSOMAL PROTECTIVE PROTEIN (Homo sapiens)	4 / 5	PRO A  11 VAL A 318 GLY A  65 VAL A  75	PRO  A  11 ( 1.1A) VAL  A 318 ( 0.6A) GLY  A  65 ( 0.0A) VAL  A  75 ( 0.6A)	0.94A	6ak3B-4mwtA: undetectable	6ak3B-4mwtA: 10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AK3_B_P2EB1201_1 (PROSTAGLANDIN E2 RECEPTOR EP3 SUBTYPE,SOLUBLE CYTOCHROME B562)	4mwt	LYSOSOMAL PROTECTIVE PROTEIN (Homo sapiens)	4 / 5	PRO A  11 VAL A 318 GLY A  71 VAL A  75	PRO  A  11 ( 1.1A) VAL  A 318 ( 0.6A) GLY  A  71 ( 0.0A) VAL  A  75 ( 0.6A)	1.01A	6ak3B-4mwtA: undetectable	6ak3B-4mwtA: 10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AK3_B_P2EB1201_1 (PROSTAGLANDIN E2 RECEPTOR EP3 SUBTYPE,SOLUBLE CYTOCHROME B562)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	4 / 5	PRO A1079 VAL A1125 GLY A1274 VAL A1150	None None PRO  A1602 (-3.7A) None	0.99A	6ak3B-5vadA: undetectable	6ak3B-5vadA: 10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B1E_B_LF7B801_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	10 / 12	ARG A 106 GLU A 208 GLU A 209 TYR A 527 SER A 613 VAL A 639 TYR A 645 TYR A 649 ASN A 691 VAL A 692	ILE  A 801 (-4.2A) ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A) None	0.80A	6b1eB-5yp3A: 34.7	6b1eB-5yp3A: 8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B1E_B_LF7B801_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	10 / 12	GLU A 208 GLU A 209 TYR A 527 SER A 613 VAL A 639 TYR A 645 TYR A 649 ASN A 691 VAL A 692 HIS A 721	ILE  A 801 (-3.4A) ILE  A 801 (-2.7A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A) PRO  A 802 (-3.8A) ILE  A 801 (-3.1A) None ILE  A 801 (-4.5A)	0.34A	6b1eB-5yp3A: 34.7	6b1eB-5yp3A: 8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B1E_B_LF7B801_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	5 / 12	GLU A 208 TYR A 527 SER A 613 VAL A 639 TYR A 645	ILE  A 801 (-3.4A) PRO  A 802 (-4.7A) PRO  A 802 (-1.3A) None PRO  A 802 (-4.0A)	1.05A	6b1eB-5yp3A: 34.7	6b1eB-5yp3A: 8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B1E_B_LF7B801_1 (DIPEPTIDYL PEPTIDASE 4)	5yp3	DIPEPTIDYL AMINOPEPTIDASE 4 (Pseudoxanthomona s mexicana)	5 / 12	TYR A 617 TYR A 645 ASN A 691 VAL A 692 HIS A 721	None PRO  A 802 (-4.0A) ILE  A 801 (-3.1A) None ILE  A 801 (-4.5A)	1.11A	6b1eB-5yp3A: 34.7	6b1eB-5yp3A: 8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B5Y_A_9F2A302_1 (BETA-LACTAMASE)	1woj	2',3'-CYCLIC-NUCLEOT IDE 3'-PHOSPHODIESTERASE (Homo sapiens)	5 / 9	PRO A 167 TYR A 169 THR A 233 THR A 234 ASP A 252	PRO  A 167 ( 1.1A) TYR  A 169 ( 1.3A) THR  A 233 (-0.9A) THR  A 234 ( 0.9A) ASP  A 252 ( 0.6A)	1.36A	6b5yA-1wojA: 0.0 6b5yB-1wojA: undetectable	6b5yA-1wojA: 18.18 6b5yB-1wojA: 18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B68_A_9F2A302_1 (BETA-LACTAMASE)	1woj	2',3'-CYCLIC-NUCLEOT IDE 3'-PHOSPHODIESTERASE (Homo sapiens)	5 / 9	PRO A 167 TYR A 169 THR A 233 THR A 234 ASP A 252	PRO  A 167 ( 1.1A) TYR  A 169 ( 1.3A) THR  A 233 (-0.9A) THR  A 234 ( 0.9A) ASP  A 252 ( 0.6A)	1.36A	6b68A-1wojA: 0.0 6b68B-1wojA: 0.0	6b68A-1wojA: 18.18 6b68B-1wojA: 18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B68_C_9F2C302_1 (BETA-LACTAMASE)	1woj	2',3'-CYCLIC-NUCLEOT IDE 3'-PHOSPHODIESTERASE (Homo sapiens)	5 / 10	PRO A 167 TYR A 169 THR A 233 THR A 234 ASP A 252	PRO  A 167 ( 1.1A) TYR  A 169 ( 1.3A) THR  A 233 (-0.9A) THR  A 234 ( 0.9A) ASP  A 252 ( 0.6A)	1.35A	6b68C-1wojA: 0.0 6b68D-1wojA: 0.0	6b68C-1wojA: 18.18 6b68D-1wojA: 18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B69_A_9F2A302_1 (BETA-LACTAMASE)	1woj	2',3'-CYCLIC-NUCLEOT IDE 3'-PHOSPHODIESTERASE (Homo sapiens)	5 / 9	PRO A 167 TYR A 169 THR A 233 THR A 234 ASP A 252	PRO  A 167 ( 1.1A) TYR  A 169 ( 1.3A) THR  A 233 (-0.9A) THR  A 234 ( 0.9A) ASP  A 252 ( 0.6A)	1.33A	6b69A-1wojA: 0.0 6b69B-1wojA: 0.0	6b69A-1wojA: 18.18 6b69B-1wojA: 18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B69_C_9F2C302_1 (BETA-LACTAMASE)	1woj	2',3'-CYCLIC-NUCLEOT IDE 3'-PHOSPHODIESTERASE (Homo sapiens)	5 / 9	PRO A 167 TYR A 169 THR A 233 THR A 234 ASP A 252	PRO  A 167 ( 1.1A) TYR  A 169 ( 1.3A) THR  A 233 (-0.9A) THR  A 234 ( 0.9A) ASP  A 252 ( 0.6A)	1.36A	6b69C-1wojA: 0.0 6b69D-1wojA: 0.0	6b69C-1wojA: 18.18 6b69D-1wojA: 18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6A_C_9F2C302_1 (BETA-LACTAMASE)	1woj	2',3'-CYCLIC-NUCLEOT IDE 3'-PHOSPHODIESTERASE (Homo sapiens)	5 / 9	PRO A 167 TYR A 169 THR A 233 THR A 234 ASP A 252	PRO  A 167 ( 1.1A) TYR  A 169 ( 1.3A) THR  A 233 (-0.9A) THR  A 234 ( 0.9A) ASP  A 252 ( 0.6A)	1.38A	6b6aC-1wojA: 0.0 6b6aD-1wojA: undetectable	6b6aC-1wojA: 18.18 6b6aD-1wojA: 18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BER_A_DVAA2_0 (E(DVA)DP(DGL)(DHI)(D PR)N(DAL)(DPR))	3wd7	TYPE III POLYKETIDE SYNTHASES ACRIDONE SYNTHASE (Citrus x microcarpa)	3 / 3	GLU A 179 ASP A 227 PRO A 228	GLU  A 179 ( 0.6A) ASP  A 227 ( 0.6A) PRO  A 228 ( 1.1A)	0.31A	6berA-3wd7A: undetectable	6berA-3wd7A: 3.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BER_A_DVAA2_0 (E(DVA)DP(DGL)(DHI)(D PR)N(DAL)(DPR))	3whl	PROTEASOME-ACTIVATIN G NUCLEOTIDASE, 26S PROTEASE REGULATORY SUBUNIT 6A (Pyrococcus furiosus; Saccharomyces cerevisiae)	3 / 3	GLU A 208 ASP A 213 PRO A 214	GLU  A 208 ( 0.6A) ASP  A 213 ( 0.6A) PRO  A 214 ( 1.1A)	0.50A	6berA-3whlA: undetectable	6berA-3whlA: 6.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BM5_A_SAMA1301_0 (METHIONINE SYNTHASE)	2nvv	ACETYL-COA HYDROLASE/TRANSFERAS E FAMILY PROTEIN (Porphyromonas gingivalis)	5 / 11	ASP A 178 PRO A 176 ARG A 182 PRO A  82 TYR A 117	ASP  A 178 ( 0.6A) PRO  A 176 ( 1.1A) ARG  A 182 ( 0.6A) PRO  A  82 ( 1.1A) TYR  A 117 ( 1.3A)	1.27A	6bm5A-2nvvA: undetectable	6bm5A-2nvvA: 21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BRD_B_RFPB502_2 (RIFAMPIN MONOOXYGENASE)	2ogs	THERMOSTABLE CARBOXYLESTERASE EST50 (Geobacillus stearothermophil us)	4 / 6	VAL A 273 LEU A 284 ARG A 282 PRO A 230	VAL  A 273 ( 0.6A) LEU  A 284 ( 0.6A) ARG  A 282 ( 0.6A) PRO  A 230 ( 1.1A)	1.16A	6brdB-2ogsA: undetectable	6brdB-2ogsA: 11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BXN_A_SAMA901_0 (DIPHTHAMIDE BIOSYNTHESIS ENZYME DPH2)	5mc5	XAA-PRO DIPEPTIDASE (Homo sapiens)	5 / 12	HIS A 366 VAL A 467 ARG A 450 ILE A 288 ASP A 276	PRO  A 504 (-3.8A) None PRO  A 504 (-3.7A) None MN  A 500 (-1.9A)	1.45A	6bxnA-5mc5A: undetectable	6bxnA-5mc5A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DCH_A_ACTA401_0 (SCOE PROTEIN)	4p7w	L-PROLINE CIS-4-HYDROXYLASE (Mesorhizobium japonicum)	4 / 5	HIS A 106 ASP A 108 HIS A 154 ARG A 118	CO  A 301 ( 3.3A) CO  A 301 (-2.5A) CO  A 301 ( 3.3A) PRO  A 303 ( 2.9A)	0.74A	6dchA-4p7wA: 4.2	6dchA-4p7wA: 21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DHB_A_BEZA202_0 (HEPATITIS A VIRUS CELLULAR RECEPTOR 2)	5inr	DIPEPTIDASE (Lactobacillus farciminis)	4 / 6	ARG A 318 ILE A 314 ASN A  29 ASP A  31	PRO  A 502 (-3.7A) None None None	1.23A	6dhbA-5inrA: undetectable	6dhbA-5inrA: 13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DLZ_A_CYZA1302_0 (GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT)	5w0a	GLUCANASE (Trichoderma harzianum)	5 / 10	PRO A 294 LEU A 302 SER A 213 ILE A 290 GLY A 225	PRO  A 294 ( 1.1A) LEU  A 302 ( 0.6A) SER  A 213 ( 0.0A) ILE  A 290 ( 0.7A) GLY  A 225 ( 0.0A)	1.10A	6dlzA-5w0aA: undetectable 6dlzD-5w0aA: undetectable	6dlzA-5w0aA: 20.93 6dlzD-5w0aA: 20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DLZ_C_CYZC1302_0 (GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT)	5w0a	GLUCANASE (Trichoderma harzianum)	5 / 10	ILE A 290 GLY A 225 PRO A 294 LEU A 302 SER A 213	ILE  A 290 ( 0.7A) GLY  A 225 ( 0.0A) PRO  A 294 ( 1.1A) LEU  A 302 ( 0.6A) SER  A 213 ( 0.0A)	1.10A	6dlzB-5w0aA: undetectable 6dlzC-5w0aA: undetectable	6dlzB-5w0aA: 20.93 6dlzC-5w0aA: 20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DM1_A_CYZA1302_0 (GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT)	5w0a	GLUCANASE (Trichoderma harzianum)	5 / 10	PRO A 294 LEU A 302 SER A 213 ILE A 290 GLY A 225	PRO  A 294 ( 1.1A) LEU  A 302 ( 0.6A) SER  A 213 ( 0.0A) ILE  A 290 ( 0.7A) GLY  A 225 ( 0.0A)	1.10A	6dm1A-5w0aA: undetectable 6dm1D-5w0aA: undetectable	6dm1A-5w0aA: 20.93 6dm1D-5w0aA: 20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DM1_C_CYZC1302_0 (GLUTAMATE RECEPTOR 2,VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT)	5w0a	GLUCANASE (Trichoderma harzianum)	5 / 10	ILE A 290 GLY A 225 PRO A 294 LEU A 302 SER A 213	ILE  A 290 ( 0.7A) GLY  A 225 ( 0.0A) PRO  A 294 ( 1.1A) LEU  A 302 ( 0.6A) SER  A 213 ( 0.0A)	1.10A	6dm1B-5w0aA: undetectable 6dm1C-5w0aA: undetectable	6dm1B-5w0aA: 20.93 6dm1C-5w0aA: 20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_B_TA1B501_2 (TUBULIN BETA CHAIN)	4mtp	RNA DEPENDENT RNA POLYMERASE (Japanese encephalitis virus)	4 / 5	LEU A 640 THR A 379 PRO A 368 ARG A 546	LEU  A 640 ( 0.5A) THR  A 379 ( 0.8A) PRO  A 368 ( 1.1A) ARG  A 546 ( 0.6A)	1.38A	6ew0B-4mtpA: undetectable	6ew0B-4mtpA: 7.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_D_TA1D501_2 (TUBULIN BETA CHAIN)	4mtp	RNA DEPENDENT RNA POLYMERASE (Japanese encephalitis virus)	4 / 5	LEU A 640 THR A 379 PRO A 368 ARG A 546	LEU  A 640 ( 0.5A) THR  A 379 ( 0.8A) PRO  A 368 ( 1.1A) ARG  A 546 ( 0.6A)	1.38A	6ew0D-4mtpA: undetectable	6ew0D-4mtpA: 7.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_H_TA1H501_2 (TUBULIN BETA CHAIN)	4mtp	RNA DEPENDENT RNA POLYMERASE (Japanese encephalitis virus)	4 / 5	LEU A 640 THR A 379 PRO A 368 ARG A 546	LEU  A 640 ( 0.5A) THR  A 379 ( 0.8A) PRO  A 368 ( 1.1A) ARG  A 546 ( 0.6A)	1.38A	6ew0H-4mtpA: undetectable	6ew0H-4mtpA: 7.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_I_TA1I501_2 (TUBULIN BETA CHAIN)	4mtp	RNA DEPENDENT RNA POLYMERASE (Japanese encephalitis virus)	4 / 5	LEU A 640 THR A 379 PRO A 368 ARG A 546	LEU  A 640 ( 0.5A) THR  A 379 ( 0.8A) PRO  A 368 ( 1.1A) ARG  A 546 ( 0.6A)	1.38A	6ew0I-4mtpA: undetectable	6ew0I-4mtpA: 7.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FBV_D_FI8D1904_1 (DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA')	5mc5	XAA-PRO DIPEPTIDASE (Homo sapiens)	4 / 8	ARG A 450 GLU A 412 VAL A 376 ARG A 469	PRO  A 504 (-3.7A) MN  A 499 (-2.8A) None None	1.03A	6fbvD-5mc5A: undetectable	6fbvD-5mc5A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HLO_A_GBQA1501_0 (SUBSTANCE-P RECEPTOR,GLGA GLYCOGEN SYNTHASE,SUBSTANCE-P RECEPTOR)	1v0f	ENDO-ALPHA-SIALIDASE (Enterobacteria phage K1F)	5 / 12	PRO A 548 ILE A 571 TYR A 541 HIS A 542 THR A 524	PRO  A 548 ( 1.1A) ILE  A 571 ( 0.7A) TYR  A 541 ( 1.3A) HIS  A 542 ( 1.0A) THR  A 524 ( 0.9A)	1.29A	6hloA-1v0fA: 0.0	6hloA-1v0fA: 21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6J20_A_GBQA1201_1 (SUBSTANCE-P RECEPTOR,ENDOLYSIN)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	4 / 7	ILE A1068 GLN A1170 GLU A1171 VAL A1073	None None PRO  A1602 ( 4.7A) None	1.18A	6j20A-5vadA: undetectable	6j20A-5vadA: 21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MKE_C_FK5C201_0 (PEPTIDYLPROLYL ISOMERASE)	1zlm	OSTEOCLAST STIMULATING FACTOR 1 (Homo sapiens)	4 / 4	ASP A  43 ILE A  61 PRO A  62 LEU A  60	ASP  A  43 ( 0.6A) ILE  A  61 ( 0.5A) PRO  A  62 ( 1.1A) LEU  A  60 ( 0.6A)	1.36A	6mkeB-1zlmA: undetectable	6mkeB-1zlmA: 15.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6MN8_A_HFGA603_0 (UNCHARACTERIZED PROTEIN)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	5 / 12	GLU A1154 THR A1240 SER A1272 TRP A1273 GLY A1274	91Y  A1601 (-4.6A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.3A) None PRO  A1602 (-3.7A)	0.69A	6mn8A-5vadA: 45.7	6mn8A-5vadA: 59.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6MN8_A_HFGA603_0 (UNCHARACTERIZED PROTEIN)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	11 / 12	LEU A1087 GLU A1100 VAL A1101 PRO A1120 TRP A1169 GLU A1171 HIS A1173 THR A1240 SER A1272 TRP A1273 GLY A1274	None None None None None PRO  A1602 ( 4.7A) PRO  A1602 ( 4.5A) 91Y  A1601 (-4.2A) PRO  A1602 (-3.3A) None PRO  A1602 (-3.7A)	0.69A	6mn8A-5vadA: 45.7	6mn8A-5vadA: 59.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6MN8_A_HFGA603_1 (UNCHARACTERIZED PROTEIN)	5vad	BIFUNCTIONAL GLUTAMATE/PROLINE--T RNA LIGASE (Homo sapiens)	4 / 4	THR A1121 GLU A1123 ARG A1152 HIS A1242	PRO  A1602 (-3.5A) PRO  A1602 (-2.8A) PRO  A1602 ( 3.4A) PRO  A1602 (-4.1A)	0.45A	6mn8A-5vadA: 45.7	6mn8A-5vadA: 59.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NCS_A_ACTA303_0 (N-ACETYLNEURAMINIC ACID (SIALIC ACID) SYNTHETASE)	3r9r	PHOSPHORIBOSYLAMINOI MIDAZOLE-SUCCINOCARB OXAMIDE SYNTHASE (Mycobacteroides abscessus)	3 / 3	ILE A 177 THR A 176 PRO A 138	ILE  A 177 ( 0.7A) THR  A 176 ( 0.8A) PRO  A 138 ( 1.1A)	0.65A	6ncsA-3r9rA: undetectable	6ncsA-3r9rA: 19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NCS_A_ACTA303_0 (N-ACETYLNEURAMINIC ACID (SIALIC ACID) SYNTHETASE)	4ikn	AP-3 COMPLEX SUBUNIT MU-1 (Rattus norvegicus)	3 / 3	ILE A 305 THR A 304 PRO A 297	ILE  A 305 ( 0.6A) THR  A 304 ( 0.8A) PRO  A 297 ( 1.1A)	0.65A	6ncsA-4iknA: undetectable	6ncsA-4iknA: 21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NKN_C_CHDC301_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	5mc5	XAA-PRO DIPEPTIDASE (Homo sapiens)	4 / 6	HIS A 377 ASP A 453 THR A 410 HIS A 255	GLY  A 503 ( 3.9A) None MN  A 499 ( 4.0A) PRO  A 504 (-4.2A)	1.35A	6nknA-5mc5A: undetectable 6nknC-5mc5A: 2.4	6nknA-5mc5A: undetectable 6nknC-5mc5A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NMP_P_CHDP302_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 3)	5mc5	XAA-PRO DIPEPTIDASE (Homo sapiens)	4 / 7	HIS A 377 ASP A 453 THR A 410 HIS A 255	GLY  A 503 ( 3.9A) None MN  A 499 ( 4.0A) PRO  A 504 (-4.2A)	1.34A	6nmpN-5mc5A: undetectable 6nmpP-5mc5A: undetectable	6nmpN-5mc5A: undetectable 6nmpP-5mc5A: undetectable