SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'PQ9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FQS_A_LYAA302_1 (THYMIDYLATE SYNTHASE)	3a0h	PHOTOSYSTEM II D2 PROTEIN (Thermosynechococ cus vulcanus)	5 / 12	TRP D 191 LEU D 279 GLY D 278 VAL D 152 ALA D 151	CLA D1004 (-4.8A) PHO D1039 ( 4.0A) PQ9 D1042 ( 4.9A) CLA D1004 (-3.9A) None	1.05A	4fqsA-3a0hD: undetectable	4fqsA-3a0hD: 20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FQS_B_LYAB302_1 (THYMIDYLATE SYNTHASE)	3a0h	PHOTOSYSTEM II D2 PROTEIN (Thermosynechococ cus vulcanus)	5 / 12	TRP D 191 LEU D 279 GLY D 278 VAL D 152 ALA D 151	CLA D1004 (-4.8A) PHO D1039 ( 4.0A) PQ9 D1042 ( 4.9A) CLA D1004 (-3.9A) None	1.07A	4fqsB-3a0hD: undetectable	4fqsB-3a0hD: 20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E4D_B_BEZB203_0 (HYDROXYNITRILE LYASE)	3a0h	PHOTOSYSTEM II CP43 PROTEIN PHOTOSYSTEM II D2 PROTEIN (Thermosynechococ cus vulcanus; Thermosynechococ cus vulcanus)	4 / 4	VAL C 466 ALA D 249 ILE C 459 THR D 221	None PQ9 D1042 (-3.2A) None None	1.07A	5e4dB-3a0hC: undetectable	5e4dB-3a0hC: 20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B54_A_OAQA302_0 (SULFOTRANSFERASE)	3a0h	PHOTOSYSTEM II CP43 PROTEIN PHOTOSYSTEM II D2 PROTEIN (Thermosynechococ cus vulcanus; Thermosynechococ cus vulcanus)	5 / 12	ILE C 459 LEU C 467 VAL D 247 PHE D 223 THR D 217	None None None None PQ9 D1042 (-2.8A)	1.08A	6b54A-3a0hC: undetectable	6b54A-3a0hC: 19.12

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4FQS_A_LYAA302_1","THYMIDYLATE SYNTHASE","3a0h","PHOTOSYSTEM II D2 PROTEIN","Thermosynechococcus vulcanus",5,"TRP D 191;LEU D 279;GLY D 278;VAL D 152;ALA D 151","CLA D1004 (-4.8A);PHO D1039 ( 4.0A);PQ9 D1042 ( 4.9A);CLA D1004 (-3.9A);None","1.05A","4fqsA-3a0hD:undetectable",null],["4FQS_B_LYAB302_1","THYMIDYLATE SYNTHASE","3a0h","PHOTOSYSTEM II D2 PROTEIN","Thermosynechococcus vulcanus",5,"TRP D 191;LEU D 279;GLY D 278;VAL D 152;ALA D 151","CLA D1004 (-4.8A);PHO D1039 ( 4.0A);PQ9 D1042 ( 4.9A);CLA D1004 (-3.9A);None","1.07A","4fqsB-3a0hD:undetectable","4fqsA-3a0hD:20.92"],["5E4D_B_BEZB203_0","HYDROXYNITRILE LYASE","3a0h","PHOTOSYSTEM II CP43 PROTEIN;PHOTOSYSTEM II D2 PROTEIN","Thermosynechococcus vulcanus;Thermosynechococcus vulcanus",4,"VAL C 466;ALA D 249;ILE C 459;THR D 221","None;PQ9 D1042 (-3.2A);None;None","1.07A","5e4dB-3a0hC:undetectable","4fqsB-3a0hD:20.92"],["6B54_A_OAQA302_0","SULFOTRANSFERASE","3a0h","PHOTOSYSTEM II CP43 PROTEIN;PHOTOSYSTEM II D2 PROTEIN","Thermosynechococcus vulcanus;Thermosynechococcus vulcanus",5,"ILE C 459;LEU C 467;VAL D 247;PHE D 223;THR D 217","None;None;None;None;PQ9 D1042 (-2.8A)","1.08A","6b54A-3a0hC:undetectable","5e4dB-3a0hC:20.36"]]