SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'PLD'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1lsh LIPOVITELLIN (LV-1N,
LV-1C)
(Ichthyomyzon
unicuspis) 		5 / 7 LEU A 416
GLU A 472
LEU A 460
LEU A 433
GLY A 434
 None
None
None
None
PLD  A2005 ( 4.6A)
 1.48A 1n13D-1lshA:
undetectable
1n13E-1lshA:
0.0		 1n13D-1lshA:
7.70
1n13E-1lshA:
4.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1lsh LIPOVITELLIN (LV-1N,
LV-1C)
(Ichthyomyzon
unicuspis) 		5 / 12 GLY A 481
ALA A 479
HIS A 746
TYR A 194
GLU A 675
 None
None
PLD  A2007 ( 3.9A)
PLD  A2005 (-4.4A)
None
 1.42A 3s8pA-1lshA:
undetectable		 3s8pA-1lshA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1lsh LIPOVITELLIN (LV-1N,
LV-1C)
(Ichthyomyzon
unicuspis) 		5 / 12 GLY A 481
ALA A 479
HIS A 746
TYR A 194
GLU A 675
 None
None
PLD  A2007 ( 3.9A)
PLD  A2005 (-4.4A)
None
 1.43A 3s8pB-1lshA:
0.0		 3s8pB-1lshA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 1lsh LIPOVITELLIN (LV-1N,
LV-1C)
(Ichthyomyzon
unicuspis) 		4 / 5 LEU A 454
LEU A 453
LEU A 438
SER A 437
 None
None
None
PLD  A2005 (-3.1A)
 1.02A 3vhuA-1lshA:
0.0		 3vhuA-1lshA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_A_SAMA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1lsh LIPOVITELLIN (LV-1N,
LV-1C)
(Ichthyomyzon
unicuspis) 		5 / 12 GLY A 481
ALA A 479
HIS A 746
TYR A 194
GLU A 675
 None
None
PLD  A2007 ( 3.9A)
PLD  A2005 (-4.4A)
None
 1.48A 4bupA-1lshA:
undetectable		 4bupA-1lshA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1lsh LIPOVITELLIN (LV-1N,
LV-1C)
(Ichthyomyzon
unicuspis) 		5 / 12 GLY A 481
ALA A 479
HIS A 746
TYR A 194
GLU A 675
 None
None
PLD  A2007 ( 3.9A)
PLD  A2005 (-4.4A)
None
 1.43A 4bupB-1lshA:
undetectable		 4bupB-1lshA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 1lsh LIPOVITELLIN (LV-1N,
LV-1C)
(Ichthyomyzon
unicuspis) 		5 / 10 ALA A 412
LEU A 415
ILE A 394
ALA A 391
THR A 430
 None
None
None
None
PLD  A2005 ( 4.8A)
 1.11A 4j14A-1lshA:
undetectable		 4j14A-1lshA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1lsh LIPOVITELLIN (LV-1N,
LV-1C)
(Ichthyomyzon
unicuspis) 		5 / 12 GLY A 481
ALA A 479
HIS A 746
TYR A 194
GLU A 675
 None
None
PLD  A2007 ( 3.9A)
PLD  A2005 (-4.4A)
None
 1.40A 5cprB-1lshA:
undetectable		 5cprB-1lshA:
12.61