SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'PLB'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 GLY D 284
MET D 348
LEU D 353
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 (-3.3A)
PLB  D 701 ( 4.7A)
None
PLB  D 701 ( 4.8A)
None
None
None
 0.68A 1fm6D-3dzuD:
37.0		 1fm6D-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 GLY D 284
SER D 289
MET D 348
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 (-3.3A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
None
None
 0.93A 1fm6D-3dzuD:
37.0		 1fm6D-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 SER D 289
TYR D 327
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 ( 3.9A)
None
PLB  D 701 ( 4.8A)
None
None
None
 1.12A 1fm6D-3dzuD:
37.0		 1fm6D-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 TYR D 327
LEU D 353
MET D 364
HIS D 449
LEU D 469
TYR D 473
 None
None
PLB  D 701 ( 4.8A)
None
None
None
 0.89A 1fm6D-3dzuD:
37.0		 1fm6D-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		4 / 4 ILE D 281
LEU D 330
VAL D 339
ILE D 341
 PLB  D 701 (-4.6A)
PLB  D 701 ( 4.1A)
None
PLB  D 701 (-3.6A)
 0.20A 1fm6D-3dzuD:
37.0		 1fm6D-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 ILE D 281
PHE D 282
GLY D 284
SER D 289
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 (-4.6A)
None
PLB  D 701 (-3.3A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.8A)
None
None
None
 0.71A 1fm6X-3dzuD:
37.1		 1fm6X-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
CYH D 285
TYR D 327
MET D 364
HIS D 449
 None
PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.8A)
None
 1.05A 1fm6X-3dzuD:
37.1		 1fm6X-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
GLY D 284
CYH D 285
MET D 364
HIS D 449
 None
PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 4.8A)
None
 1.02A 1fm6X-3dzuD:
37.1		 1fm6X-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 PHE D 282
TYR D 327
MET D 364
HIS D 449
LEU D 469
TYR D 473
 None
None
PLB  D 701 ( 4.8A)
None
None
None
 0.85A 1fm6X-3dzuD:
37.1		 1fm6X-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 CYH D 285
TYR D 327
LEU D 330
MET D 364
HIS D 449
 PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 0.97A 1zgyA-3dzuD:
37.2		 1zgyA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 GLY D 284
CYH D 285
LEU D 330
MET D 364
HIS D 449
 PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 1.06A 1zgyA-3dzuD:
37.2		 1zgyA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 GLY D 284
CYH D 285
TYR D 473
LEU D 469
HIS D 449
 PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
None
None
None
 1.49A 1zgyA-3dzuD:
37.2		 1zgyA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 GLY D 284
SER D 289
LEU D 330
LEU D 353
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 (-3.3A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.8A)
None
None
None
 0.69A 1zgyA-3dzuD:
37.2		 1zgyA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
GLY D 284
CYH D 285
LEU D 330
MET D 364
 None
PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
 1.10A 1zgyA-3dzuD:
37.2		 1zgyA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 PHE D 282
GLY D 284
SER D 289
LEU D 330
LEU D 353
MET D 364
LEU D 469
TYR D 473
 None
PLB  D 701 (-3.3A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.8A)
None
None
 0.78A 1zgyA-3dzuD:
37.2		 1zgyA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 TYR D 327
LEU D 330
LEU D 353
MET D 364
HIS D 449
LEU D 469
TYR D 473
 None
PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.8A)
None
None
None
 0.88A 1zgyA-3dzuD:
37.2		 1zgyA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		4 / 5 ILE D 281
ILE D 326
ILE D 341
MET D 348
 PLB  D 701 (-4.6A)
PLB  D 701 ( 4.5A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
 0.35A 1zgyA-3dzuD:
37.2		 1zgyA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_A_BRLA1_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 PHE D 282
CYH D 285
TYR D 327
LEU D 330
MET D 364
HIS D 449
 None
PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 1.12A 2prgA-3dzuD:
36.9		 2prgA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_A_BRLA1_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 PHE D 282
GLY D 284
CYH D 285
GLN D 286
LEU D 330
MET D 364
 None
PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
 1.01A 2prgA-3dzuD:
36.9		 2prgA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_A_BRLA1_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 PHE D 282
GLY D 284
CYH D 285
LEU D 330
MET D 364
HIS D 449
 None
PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 1.09A 2prgA-3dzuD:
36.9		 2prgA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_A_BRLA1_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 PHE D 282
GLY D 284
GLN D 286
LEU D 330
MET D 348
MET D 364
TYR D 473
 None
PLB  D 701 (-3.3A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
 0.67A 2prgA-3dzuD:
36.9		 2prgA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_A_BRLA1_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 PHE D 282
GLY D 284
LEU D 330
MET D 348
MET D 364
HIS D 449
TYR D 473
 None
PLB  D 701 (-3.3A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
None
 0.76A 2prgA-3dzuD:
36.9		 2prgA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_A_BRLA1_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 PHE D 282
TYR D 327
LEU D 330
MET D 364
HIS D 449
TYR D 473
 None
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
 1.00A 2prgA-3dzuD:
36.9		 2prgA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 CYH D 285
TYR D 327
LEU D 330
VAL D 339
MET D 364
HIS D 449
 PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.8A)
None
 0.93A 2prgB-3dzuD:
35.8		 2prgB-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
CYH D 285
LEU D 330
VAL D 339
MET D 364
 None
PLB  D 701 (-3.2A)
PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.8A)
 1.00A 2prgB-3dzuD:
35.8		 2prgB-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 PHE D 282
SER D 289
LEU D 330
VAL D 339
MET D 364
LEU D 469
TYR D 473
 None
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.8A)
None
None
 0.72A 2prgB-3dzuD:
35.8		 2prgB-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 SER D 289
LEU D 330
VAL D 339
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.8A)
None
None
None
 0.81A 2prgB-3dzuD:
35.8		 2prgB-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 TYR D 327
LEU D 330
VAL D 339
MET D 364
HIS D 449
LEU D 469
TYR D 473
 None
PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.8A)
None
None
None
 0.95A 2prgB-3dzuD:
35.8		 2prgB-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XKW_A_P1BA1478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 CYH D 285
HIS D 323
TYR D 327
HIS D 449
TYR D 473
 PLB  D 701 (-3.2A)
None
None
None
None
 1.22A 2xkwA-3dzuD:
37.5		 2xkwA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XKW_A_P1BA1478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		9 / 12 CYH D 285
SER D 289
LEU D 330
ILE D 341
MET D 348
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
None
None
 0.69A 2xkwA-3dzuD:
37.5		 2xkwA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XKW_A_P1BA1478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		9 / 12 CYH D 285
TYR D 327
LEU D 330
ILE D 341
MET D 348
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
None
None
 0.84A 2xkwA-3dzuD:
37.5		 2xkwA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XKW_A_P1BA1478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		9 / 12 PHE D 282
CYH D 285
SER D 289
LEU D 330
ILE D 341
MET D 348
MET D 364
LEU D 469
TYR D 473
 None
PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
None
 0.49A 2xkwA-3dzuD:
37.5		 2xkwA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 7 LEU D 255
ILE D 281
GLN D 286
ALA D 292
ILE D 326
 None
PLB  D 701 (-4.6A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.5A)
 0.68A 2xkwA-3dzuD:
37.5		 2xkwA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 ILE D 249
CYH D 285
SER D 289
ALA D 292
LEU D 330
ILE D 341
MET D 348
MET D 364
 None
PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
 0.40A 2xkwB-3dzuD:
34.5		 2xkwB-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 6 LEU D 255
ARG D 280
ILE D 281
ILE D 326
MET D 329
LEU D 333
 None
None
PLB  D 701 (-4.6A)
PLB  D 701 ( 4.5A)
None
PLB  D 701 (-4.4A)
 0.66A 2xkwB-3dzuD:
34.5		 2xkwB-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 10 ARG D 280
ILE D 281
GLY D 284
CYH D 285
LEU D 330
ILE D 341
MET D 348
MET D 364
 None
PLB  D 701 (-4.6A)
PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
 0.66A 3adsA-3dzuD:
37.2		 3adsA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 CYH D 285
SER D 289
LEU D 330
LEU D 353
PHE D 363
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
None
None
None
None
None
 0.85A 3adsA-3dzuD:
37.2		 3adsA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 PHE D 282
CYH D 285
SER D 289
LEU D 353
PHE D 363
HIS D 449
LEU D 469
 None
PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
None
None
None
None
 1.00A 3adsA-3dzuD:
37.2		 3adsA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 6 ILE D 281
ILE D 326
LEU D 356
PHE D 360
MET D 364
 PLB  D 701 (-4.6A)
PLB  D 701 ( 4.5A)
None
None
PLB  D 701 ( 4.8A)
 0.54A 3adsA-3dzuD:
37.2		 3adsA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 6 ILE D 326
TYR D 327
LEU D 356
PHE D 360
MET D 364
 PLB  D 701 ( 4.5A)
None
None
None
PLB  D 701 ( 4.8A)
 0.62A 3adsA-3dzuD:
37.2		 3adsA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		10 / 12 ILE D 281
CYH D 285
SER D 289
ALA D 292
ILE D 326
LEU D 330
LEU D 333
VAL D 339
ILE D 341
MET D 364
 PLB  D 701 (-4.6A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.5A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-4.4A)
None
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.8A)
 0.54A 3adsB-3dzuD:
34.0		 3adsB-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		10 / 12 ILE D 281
GLY D 284
CYH D 285
SER D 289
ALA D 292
ILE D 326
LEU D 330
VAL D 339
ILE D 341
MET D 364
 PLB  D 701 (-4.6A)
PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.5A)
PLB  D 701 ( 4.1A)
None
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.8A)
 0.45A 3adsB-3dzuD:
34.0		 3adsB-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 CYH D 285
GLN D 286
SER D 289
LEU D 330
LEU D 353
PHE D 363
LEU D 469
 PLB  D 701 (-3.2A)
None
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
None
None
None
 0.79A 3adxA-3dzuD:
37.0		 3adxA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 CYH D 285
GLN D 286
SER D 289
TYR D 327
LEU D 330
LEU D 353
HIS D 449
LEU D 469
 PLB  D 701 (-3.2A)
None
PLB  D 701 ( 3.9A)
None
PLB  D 701 ( 4.1A)
None
None
None
 0.74A 3adxA-3dzuD:
37.0		 3adxA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 CYH D 285
HIS D 323
TYR D 327
HIS D 449
TYR D 473
 PLB  D 701 (-3.2A)
None
None
None
None
 1.26A 3adxA-3dzuD:
37.0		 3adxA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 CYH D 285
SER D 289
LEU D 330
LEU D 353
PHE D 363
LEU D 469
TYR D 473
 PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
None
None
None
None
 0.68A 3adxA-3dzuD:
37.0		 3adxA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 CYH D 285
SER D 289
TYR D 327
LEU D 330
LEU D 353
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
None
PLB  D 701 ( 4.1A)
None
None
None
None
 0.78A 3adxA-3dzuD:
37.0		 3adxA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 PHE D 282
GLN D 286
SER D 289
LEU D 353
PHE D 363
LEU D 469
 None
None
PLB  D 701 ( 3.9A)
None
None
None
 1.03A 3adxA-3dzuD:
37.0		 3adxA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 PHE D 282
GLN D 286
SER D 289
TYR D 327
LEU D 353
HIS D 449
LEU D 469
 None
None
PLB  D 701 ( 3.9A)
None
None
None
None
 0.84A 3adxA-3dzuD:
37.0		 3adxA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 7 ILE D 281
ILE D 326
LEU D 356
PHE D 360
MET D 364
 PLB  D 701 (-4.6A)
PLB  D 701 ( 4.5A)
None
None
PLB  D 701 ( 4.8A)
 0.51A 3adxA-3dzuD:
37.0		 3adxA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 7 ILE D 281
LEU D 356
PHE D 360
MET D 364
LYS D 367
 PLB  D 701 (-4.6A)
None
None
PLB  D 701 ( 4.8A)
None
 1.09A 3adxA-3dzuD:
37.0		 3adxA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		11 / 12 LEU D 228
GLY D 284
CYH D 285
SER D 289
ALA D 292
ILE D 326
LEU D 330
LEU D 333
VAL D 339
ILE D 341
MET D 364
 None
PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.5A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-4.4A)
None
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.8A)
 0.61A 3adxB-3dzuD:
34.2		 3adxB-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 GLY D 284
CYH D 285
HIS D 323
LEU D 330
MET D 364
LEU D 469
TYR D 473
 PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
 0.68A 3cs8A-3dzuD:
36.3		 3cs8A-3dzuD:
92.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 GLY D 284
CYH D 285
ILE D 326
LEU D 330
MET D 364
LEU D 469
TYR D 473
 PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 4.5A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
 0.61A 3cs8A-3dzuD:
36.3		 3cs8A-3dzuD:
92.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 GLY D 284
CYH D 285
LEU D 330
MET D 364
HIS D 449
TYR D 473
 PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
 1.10A 3cs8A-3dzuD:
36.3		 3cs8A-3dzuD:
92.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 GLY D 284
SER D 289
ILE D 326
LEU D 330
MET D 364
LEU D 469
TYR D 473
 PLB  D 701 (-3.3A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.5A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
 0.76A 3cs8A-3dzuD:
36.3		 3cs8A-3dzuD:
92.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 GLY D 284
SER D 289
LEU D 330
MET D 364
HIS D 449
TYR D 473
 PLB  D 701 (-3.3A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
 1.17A 3cs8A-3dzuD:
36.3		 3cs8A-3dzuD:
92.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 HIS D 323
LEU D 330
MET D 364
LYS D 367
LEU D 469
TYR D 473
 None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
None
 0.95A 3cs8A-3dzuD:
36.3		 3cs8A-3dzuD:
92.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 ILE D 326
LEU D 330
MET D 364
LYS D 367
LEU D 469
TYR D 473
 PLB  D 701 ( 4.5A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
None
 0.86A 3cs8A-3dzuD:
36.3		 3cs8A-3dzuD:
92.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZY_D_BRLD478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 PHE D 282
CYH D 285
HIS D 323
TYR D 327
VAL D 339
LEU D 353
MET D 364
HIS D 449
 None
PLB  D 701 (-3.2A)
None
None
None
None
PLB  D 701 ( 4.8A)
None
 0.96A 3dzyD-3dzuD:
44.4		 3dzyD-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZY_D_BRLD478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 PHE D 282
CYH D 285
TYR D 327
LEU D 330
VAL D 339
LEU D 353
MET D 364
HIS D 449
 None
PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
None
None
PLB  D 701 ( 4.8A)
None
 0.90A 3dzyD-3dzuD:
44.4		 3dzyD-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZY_D_BRLD478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 PHE D 282
HIS D 323
TYR D 327
VAL D 339
LEU D 353
MET D 364
HIS D 449
TYR D 473
 None
None
None
None
None
PLB  D 701 ( 4.8A)
None
None
 0.89A 3dzyD-3dzuD:
44.4		 3dzyD-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZY_D_BRLD478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		9 / 12 PHE D 282
SER D 289
TYR D 327
LEU D 330
VAL D 339
LEU D 353
MET D 364
HIS D 449
TYR D 473
 None
PLB  D 701 ( 3.9A)
None
PLB  D 701 ( 4.1A)
None
None
PLB  D 701 ( 4.8A)
None
None
 0.89A 3dzyD-3dzuD:
44.4		 3dzyD-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G8I_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 SER D 289
MET D 334
MET D 364
HIS D 449
TYR D 473
 PLB  D 701 ( 3.9A)
None
PLB  D 701 ( 4.8A)
None
None
 1.33A 3g8iA-3dzuD:
34.3		 3g8iA-3dzuD:
61.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 7 LEU D 255
GLN D 286
LEU D 330
LEU D 353
LEU D 469
 None
None
PLB  D 701 ( 4.1A)
None
None
 0.72A 3g8iA-3dzuD:
34.3		 3g8iA-3dzuD:
61.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 CYH D 285
TYR D 327
LEU D 330
VAL D 339
HIS D 449
 PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
None
None
 0.91A 3g9eA-3dzuD:
37.2		 3g9eA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 GLY D 284
CYH D 285
LEU D 330
VAL D 339
HIS D 449
 PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 4.1A)
None
None
 0.93A 3g9eA-3dzuD:
37.2		 3g9eA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 GLY D 284
LEU D 330
VAL D 339
ILE D 341
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 (-3.3A)
PLB  D 701 ( 4.1A)
None
PLB  D 701 (-3.6A)
None
None
None
 0.68A 3g9eA-3dzuD:
37.2		 3g9eA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 GLY D 284
SER D 289
ILE D 341
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 (-3.3A)
PLB  D 701 ( 3.9A)
PLB  D 701 (-3.6A)
None
None
None
 0.91A 3g9eA-3dzuD:
37.2		 3g9eA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 SER D 289
TYR D 327
ILE D 341
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 ( 3.9A)
None
PLB  D 701 (-3.6A)
None
None
None
 1.00A 3g9eA-3dzuD:
37.2		 3g9eA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 TYR D 327
LEU D 330
VAL D 339
ILE D 341
HIS D 449
LEU D 469
TYR D 473
 None
PLB  D 701 ( 4.1A)
None
PLB  D 701 (-3.6A)
None
None
None
 0.80A 3g9eA-3dzuD:
37.2		 3g9eA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GWX_A_EPAA1_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 10 PHE D 282
GLN D 286
ILE D 326
MET D 329
LEU D 353
 None
None
PLB  D 701 ( 4.5A)
None
None
 0.70A 3gwxA-3dzuD:
34.3		 3gwxA-3dzuD:
42.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GWX_B_EPAB3_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 GLU D 295
LEU D 330
HIS D 449
LEU D 469
TYR D 473
 None
PLB  D 701 ( 4.1A)
None
None
None
 1.03A 3gwxB-3dzuD:
34.4		 3gwxB-3dzuD:
42.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GWX_B_EPAB3_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 LEU D 255
PHE D 282
GLN D 286
ILE D 326
MET D 329
LEU D 353
 None
None
None
PLB  D 701 ( 4.5A)
None
None
 0.72A 3gwxB-3dzuD:
34.4		 3gwxB-3dzuD:
42.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QT0_A_486A4_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 ALA D 292
LEU D 330
ILE D 341
MET D 348
MET D 364
HIS D 449
 PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
 1.10A 3qt0A-3dzuD:
36.1		 3qt0A-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QT0_A_486A4_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 ALA D 292
TYR D 327
LEU D 330
ILE D 341
MET D 364
HIS D 449
 PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.8A)
None
 1.16A 3qt0A-3dzuD:
36.1		 3qt0A-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QT0_A_486A4_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 CYH D 285
ALA D 292
TYR D 327
LEU D 330
ILE D 341
HIS D 449
 PLB  D 701 (-3.2A)
PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
None
 1.12A 3qt0A-3dzuD:
36.1		 3qt0A-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QT0_A_486A4_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 SER D 289
ALA D 292
ILE D 341
MET D 348
HIS D 449
 PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
None
 0.87A 3qt0A-3dzuD:
36.1		 3qt0A-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QT0_A_486A4_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 SER D 289
ALA D 292
TYR D 327
ILE D 341
HIS D 449
 PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
None
PLB  D 701 (-3.6A)
None
 0.97A 3qt0A-3dzuD:
36.1		 3qt0A-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SP6_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
SER D 289
MET D 364
HIS D 449
TYR D 473
 None
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.8A)
None
None
 0.70A 3sp6A-3dzuD:
35.5		 3sp6A-3dzuD:
43.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SP9_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU D 255
PHE D 282
ILE D 326
HIS D 449
TYR D 473
 None
None
PLB  D 701 ( 4.5A)
None
None
 1.30A 3sp9A-3dzuD:
34.5		 3sp9A-3dzuD:
42.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SP9_B_IL2B901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU D 255
PHE D 282
ILE D 326
HIS D 449
TYR D 473
 None
None
PLB  D 701 ( 4.5A)
None
None
 1.29A 3sp9B-3dzuD:
34.3		 3sp9B-3dzuD:
42.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VN2_A_TLSA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 PHE D 282
CYH D 285
TYR D 327
LEU D 330
LEU D 353
MET D 364
HIS D 449
 None
PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.8A)
None
 1.03A 3vn2A-3dzuD:
37.7		 3vn2A-3dzuD:
93.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VN2_A_TLSA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		10 / 12 PHE D 282
SER D 289
HIS D 323
ILE D 326
TYR D 327
LEU D 330
LEU D 353
MET D 364
HIS D 449
TYR D 473
 None
PLB  D 701 ( 3.9A)
None
PLB  D 701 ( 4.5A)
None
PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.8A)
None
None
 0.86A 3vn2A-3dzuD:
37.7		 3vn2A-3dzuD:
93.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VN2_A_TLSA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 SER D 289
HIS D 323
ILE D 326
LEU D 330
PHE D 282
TYR D 473
 PLB  D 701 ( 3.9A)
None
PLB  D 701 ( 4.5A)
PLB  D 701 ( 4.1A)
None
None
 1.31A 3vn2A-3dzuD:
37.7		 3vn2A-3dzuD:
93.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 368
VAL D 339
ILE D 341
GLU D 365
ILE D 445
 None
None
PLB  D 701 (-3.6A)
None
None
 1.16A 4a97B-3dzuD:
undetectable
4a97C-3dzuD:
undetectable		 4a97B-3dzuD:
21.48
4a97C-3dzuD:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		4 / 8 PHE D 368
VAL D 339
ILE D 341
GLU D 365
 None
None
PLB  D 701 (-3.6A)
None
 1.10A 4a97C-3dzuD:
0.9		 4a97C-3dzuD:
21.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EMA_A_BRLA601_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 CYH D 285
TYR D 327
LEU D 330
MET D 364
HIS D 449
 PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 0.94A 4emaA-3dzuD:
37.4		 4emaA-3dzuD:
90.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EMA_A_BRLA601_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 GLY D 284
CYH D 285
LEU D 330
MET D 364
HIS D 449
 PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 1.06A 4emaA-3dzuD:
37.4		 4emaA-3dzuD:
90.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EMA_A_BRLA601_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 GLY D 284
CYH D 285
TYR D 473
LEU D 469
HIS D 449
 PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
None
None
None
 1.45A 4emaA-3dzuD:
37.4		 4emaA-3dzuD:
90.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EMA_A_BRLA601_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 GLY D 284
SER D 289
LEU D 330
MET D 348
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 (-3.3A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
None
None
 0.73A 4emaA-3dzuD:
37.4		 4emaA-3dzuD:
90.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EMA_A_BRLA601_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 TYR D 327
LEU D 330
MET D 348
MET D 364
HIS D 449
LEU D 469
TYR D 473
 None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
None
None
 0.89A 4emaA-3dzuD:
37.4		 4emaA-3dzuD:
90.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		3 / 3 PHE D 282
VAL D 339
ILE D 341
 None
None
PLB  D 701 (-3.6A)
 0.18A 4emaA-3dzuD:
37.4		 4emaA-3dzuD:
90.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 CYH D 285
TYR D 327
VAL D 339
MET D 364
HIS D 449
 PLB  D 701 (-3.2A)
None
None
PLB  D 701 ( 4.8A)
None
 0.93A 4o8fA-3dzuD:
35.9		 4o8fA-3dzuD:
94.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 PHE D 282
ARG D 288
SER D 289
MET D 348
LEU D 469
TYR D 473
 None
PLB  D 701 (-3.3A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.7A)
None
None
 1.10A 4o8fA-3dzuD:
35.9		 4o8fA-3dzuD:
94.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 PHE D 282
SER D 289
VAL D 339
MET D 348
MET D 364
LEU D 469
TYR D 473
 None
PLB  D 701 ( 3.9A)
None
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
None
 0.56A 4o8fA-3dzuD:
35.9		 4o8fA-3dzuD:
94.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 SER D 289
VAL D 339
MET D 348
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 ( 3.9A)
None
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
None
None
 0.81A 4o8fA-3dzuD:
35.9		 4o8fA-3dzuD:
94.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 TYR D 327
VAL D 339
MET D 348
MET D 364
HIS D 449
LEU D 469
TYR D 473
 None
None
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
None
None
 0.94A 4o8fA-3dzuD:
35.9		 4o8fA-3dzuD:
94.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_A_BRLA501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		4 / 5 GLY D 284
LEU D 330
ILE D 341
LEU D 353
 PLB  D 701 (-3.3A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
None
 0.29A 4o8fA-3dzuD:
35.9		 4o8fA-3dzuD:
94.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_B_BRLB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 CYH D 285
LEU D 330
VAL D 339
MET D 348
MET D 364
HIS D 449
 PLB  D 701 (-3.2A)
PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
 0.81A 4o8fB-3dzuD:
20.5		 4o8fB-3dzuD:
94.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_B_BRLB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 LEU D 330
VAL D 339
MET D 348
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
None
None
 0.72A 4o8fB-3dzuD:
20.5		 4o8fB-3dzuD:
94.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_B_BRLB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 SER D 289
LEU D 330
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
None
None
None
 0.94A 4o8fB-3dzuD:
20.5		 4o8fB-3dzuD:
94.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_B_BRLB501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 6 ILE D 281
PHE D 282
GLY D 284
ILE D 326
ILE D 341
LEU D 353
 PLB  D 701 (-4.6A)
None
PLB  D 701 (-3.3A)
PLB  D 701 ( 4.5A)
PLB  D 701 (-3.6A)
None
 0.75A 4o8fB-3dzuD:
20.5		 4o8fB-3dzuD:
94.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 8 CYH D 285
SER D 289
LEU D 330
LEU D 333
VAL D 339
ILE D 341
MET D 364
 PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-4.4A)
None
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.8A)
 0.48A 4oj4A-3dzuD:
34.2		 4oj4A-3dzuD:
91.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		4 / 8 MET D 463
LEU D 453
HIS D 449
ILE D 326
 None
None
None
PLB  D 701 ( 4.5A)
 0.97A 4ok1A-3dzuD:
18.1		 4ok1A-3dzuD:
19.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 GLY D 284
CYH D 285
TYR D 473
LEU D 469
HIS D 449
 PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
None
None
None
 1.42A 4xldA-3dzuD:
37.2		 4xldA-3dzuD:
69.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
CYH D 285
TYR D 327
LEU D 330
HIS D 449
 None
PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
None
 1.09A 4xldA-3dzuD:
37.2		 4xldA-3dzuD:
69.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 PHE D 282
GLY D 284
CYH D 285
LEU D 330
MET D 364
HIS D 449
 None
PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 0.96A 4xldA-3dzuD:
37.2		 4xldA-3dzuD:
69.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 PHE D 282
GLY D 284
SER D 289
LEU D 330
MET D 364
HIS D 449
LEU D 469
TYR D 473
 None
PLB  D 701 (-3.3A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
None
 0.79A 4xldA-3dzuD:
37.2		 4xldA-3dzuD:
69.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 PHE D 282
TYR D 327
LEU D 330
HIS D 449
LEU D 469
TYR D 473
 None
None
PLB  D 701 ( 4.1A)
None
None
None
 0.86A 4xldA-3dzuD:
37.2		 4xldA-3dzuD:
69.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XTA_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 9 CYH D 285
SER D 289
ALA D 292
GLU D 295
MET D 329
LEU D 330
LEU D 333
ILE D 341
 PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
None
None
PLB  D 701 ( 4.1A)
PLB  D 701 (-4.4A)
PLB  D 701 (-3.6A)
 0.62A 4xtaA-3dzuD:
34.8		 4xtaA-3dzuD:
91.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XTA_B_DIFB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 8 ILE D 281
CYH D 285
SER D 289
LEU D 330
LEU D 333
ILE D 341
MET D 364
 PLB  D 701 (-4.6A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-4.4A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.8A)
 0.46A 4xtaB-3dzuD:
33.7		 4xtaB-3dzuD:
91.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
ILE D 326
MET D 364
HIS D 449
LEU D 469
 None
PLB  D 701 ( 4.5A)
PLB  D 701 ( 4.8A)
None
None
 1.02A 4xumA-3dzuD:
37.0		 4xumA-3dzuD:
91.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
ILE D 326
PHE D 363
MET D 364
LEU D 469
 None
PLB  D 701 ( 4.5A)
None
PLB  D 701 ( 4.8A)
None
 1.16A 4xumA-3dzuD:
37.0		 4xumA-3dzuD:
91.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
PHE D 363
MET D 364
LEU D 465
LEU D 469
 None
None
PLB  D 701 ( 4.8A)
None
None
 1.24A 4xumA-3dzuD:
37.0		 4xumA-3dzuD:
91.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 SER D 289
ILE D 326
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.5A)
PLB  D 701 ( 4.8A)
None
None
None
 0.84A 4xumA-3dzuD:
37.0		 4xumA-3dzuD:
91.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 SER D 289
ILE D 326
PHE D 363
MET D 364
LEU D 469
TYR D 473
 PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.5A)
None
PLB  D 701 ( 4.8A)
None
None
 0.65A 4xumA-3dzuD:
37.0		 4xumA-3dzuD:
91.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 SER D 289
PHE D 363
MET D 364
LEU D 465
LEU D 469
TYR D 473
 PLB  D 701 ( 3.9A)
None
PLB  D 701 ( 4.8A)
None
None
None
 0.71A 4xumA-3dzuD:
37.0		 4xumA-3dzuD:
91.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		4 / 7 ILE D 281
LEU D 330
ILE D 341
MET D 348
 PLB  D 701 (-4.6A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
 0.49A 4xumA-3dzuD:
37.0		 4xumA-3dzuD:
91.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		10 / 11 GLY D 284
CYH D 285
SER D 289
ALA D 292
ILE D 326
MET D 329
LEU D 330
LEU D 333
ILE D 341
MET D 348
 PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.5A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 (-4.4A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
 0.53A 4xumB-3dzuD:
34.1		 4xumB-3dzuD:
91.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JI0_D_BRLD501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 CYH D 285
TYR D 327
LEU D 330
MET D 364
HIS D 449
 PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 0.97A 5ji0D-3dzuD:
38.1		 5ji0D-3dzuD:
89.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JI0_D_BRLD501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 GLY D 284
CYH D 285
LEU D 330
MET D 364
HIS D 449
 PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 1.11A 5ji0D-3dzuD:
38.1		 5ji0D-3dzuD:
89.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JI0_D_BRLD501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 GLY D 284
SER D 289
LEU D 330
MET D 364
HIS D 449
TYR D 473
 PLB  D 701 (-3.3A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
 0.87A 5ji0D-3dzuD:
38.1		 5ji0D-3dzuD:
89.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JI0_D_BRLD501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 PHE D 282
GLY D 284
CYH D 285
GLN D 286
LEU D 330
MET D 364
 None
PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
 1.08A 5ji0D-3dzuD:
38.1		 5ji0D-3dzuD:
89.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JI0_D_BRLD501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 PHE D 282
GLY D 284
GLN D 286
SER D 289
LEU D 330
MET D 364
TYR D 473
 None
PLB  D 701 (-3.3A)
None
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 1.00A 5ji0D-3dzuD:
38.1		 5ji0D-3dzuD:
89.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JI0_D_BRLD501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 TYR D 327
LEU D 330
MET D 364
HIS D 449
TYR D 473
 None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
 0.97A 5ji0D-3dzuD:
38.1		 5ji0D-3dzuD:
89.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y2O_A_8N6A501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 CYH D 285
TYR D 327
LEU D 330
MET D 364
HIS D 449
 PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 0.94A 5y2oA-3dzuD:
37.7		 5y2oA-3dzuD:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y2O_A_8N6A501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 PHE D 282
SER D 289
LEU D 330
MET D 364
LEU D 469
TYR D 473
 None
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
 0.61A 5y2oA-3dzuD:
37.7		 5y2oA-3dzuD:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y2O_A_8N6A501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 SER D 289
LEU D 330
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
None
 0.67A 5y2oA-3dzuD:
37.7		 5y2oA-3dzuD:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y2O_A_8N6A501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 TYR D 327
LEU D 330
MET D 364
HIS D 449
LEU D 469
TYR D 473
 None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
None
 0.90A 5y2oA-3dzuD:
37.7		 5y2oA-3dzuD:
35.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 CYH D 285
TYR D 327
LEU D 330
MET D 364
HIS D 449
 PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 0.98A 5y2tA-3dzuD:
36.6		 5y2tA-3dzuD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 GLY D 284
CYH D 285
LEU D 330
MET D 364
HIS D 449
 PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 1.07A 5y2tA-3dzuD:
36.6		 5y2tA-3dzuD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 GLY D 284
LEU D 330
ILE D 341
MET D 348
MET D 364
HIS D 449
 PLB  D 701 (-3.3A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
 0.80A 5y2tA-3dzuD:
36.6		 5y2tA-3dzuD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 LEU D 255
PHE D 282
GLY D 284
GLN D 286
LEU D 330
ILE D 341
MET D 348
MET D 364
 None
None
PLB  D 701 (-3.3A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
 0.52A 5y2tA-3dzuD:
36.6		 5y2tA-3dzuD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 LEU D 255
PHE D 363
LEU D 330
ILE D 341
MET D 348
LEU D 452
 None
None
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
None
 1.45A 5y2tA-3dzuD:
36.6		 5y2tA-3dzuD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 PHE D 282
GLY D 284
CYH D 285
GLN D 286
LEU D 330
MET D 364
 None
PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
 0.89A 5y2tA-3dzuD:
36.6		 5y2tA-3dzuD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 ILE D 281
ILE D 326
TYR D 327
LEU D 330
ILE D 341
MET D 348
HIS D 449
 PLB  D 701 (-4.6A)
PLB  D 701 ( 4.5A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
None
 0.76A 5y2tB-3dzuD:
34.2		 5y2tB-3dzuD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 LEU D 255
ARG D 280
ILE D 281
GLN D 286
ILE D 326
LEU D 330
ILE D 341
MET D 348
 None
None
PLB  D 701 (-4.6A)
None
PLB  D 701 ( 4.5A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
 0.67A 5y2tB-3dzuD:
34.2		 5y2tB-3dzuD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 LEU D 255
ARG D 280
ILE D 281
ILE D 326
LEU D 330
ILE D 341
MET D 348
HIS D 449
 None
None
PLB  D 701 (-4.6A)
PLB  D 701 ( 4.5A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
None
 0.76A 5y2tB-3dzuD:
34.2		 5y2tB-3dzuD:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		10 / 12 LEU D 255
ARG D 280
ILE D 281
GLY D 284
LEU D 330
VAL D 339
ILE D 341
MET D 348
MET D 364
LEU D 469
 None
None
PLB  D 701 (-4.6A)
PLB  D 701 (-3.3A)
PLB  D 701 ( 4.1A)
None
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
 0.56A 5ycnA-3dzuD:
38.1		 5ycnA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 LEU D 255
ARG D 280
ILE D 281
LEU D 330
VAL D 339
MET D 348
LEU D 469
 None
None
PLB  D 701 (-4.6A)
PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.7A)
None
 1.46A 5ycnA-3dzuD:
38.1		 5ycnA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 LEU D 255
ILE D 281
VAL D 339
ILE D 341
MET D 348
LEU D 465
 None
PLB  D 701 (-4.6A)
None
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
None
 1.09A 5ycnA-3dzuD:
38.1		 5ycnA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 TYR D 327
LEU D 330
VAL D 339
ILE D 341
MET D 348
MET D 364
LEU D 469
 None
PLB  D 701 ( 4.1A)
None
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
 0.75A 5ycnA-3dzuD:
38.1		 5ycnA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 CYH D 285
TYR D 327
LEU D 330
MET D 364
HIS D 449
 PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 0.96A 5ycpA-3dzuD:
38.1		 5ycpA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 PHE D 282
SER D 289
LEU D 330
ILE D 341
MET D 364
LEU D 469
TYR D 473
 None
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.8A)
None
None
 0.73A 5ycpA-3dzuD:
38.1		 5ycpA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 SER D 289
LEU D 330
ILE D 341
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.8A)
None
None
None
 0.72A 5ycpA-3dzuD:
38.1		 5ycpA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 TYR D 327
LEU D 330
ILE D 341
MET D 364
HIS D 449
LEU D 469
TYR D 473
 None
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.8A)
None
None
None
 0.88A 5ycpA-3dzuD:
38.1		 5ycpA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		3 / 3 GLY D 284
VAL D 339
MET D 348
 PLB  D 701 (-3.3A)
None
PLB  D 701 ( 4.7A)
 0.23A 5ycpA-3dzuD:
38.1		 5ycpA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 GLY D 284
CYH D 285
TYR D 473
LEU D 469
HIS D 449
 PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
None
None
None
 1.45A 6md4A-3dzuD:
36.8		 6md4A-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
CYH D 285
GLN D 286
HIS D 323
TYR D 327
 None
PLB  D 701 (-3.2A)
None
None
None
 1.16A 6md4A-3dzuD:
36.8		 6md4A-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
CYH D 285
HIS D 323
TYR D 327
HIS D 449
 None
PLB  D 701 (-3.2A)
None
None
None
 1.13A 6md4A-3dzuD:
36.8		 6md4A-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 PHE D 282
GLY D 284
CYH D 285
GLN D 286
TYR D 327
LEU D 330
MET D 364
 None
PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
None
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
 0.91A 6md4A-3dzuD:
36.8		 6md4A-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 PHE D 282
GLY D 284
CYH D 285
TYR D 327
LEU D 330
MET D 364
HIS D 449
 None
PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 1.00A 6md4A-3dzuD:
36.8		 6md4A-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		9 / 12 PHE D 282
GLY D 284
GLN D 286
SER D 289
TYR D 327
LEU D 330
ILE D 341
MET D 364
TYR D 473
 None
PLB  D 701 (-3.3A)
None
PLB  D 701 ( 3.9A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.8A)
None
 0.68A 6md4A-3dzuD:
36.8		 6md4A-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		9 / 12 PHE D 282
GLY D 284
SER D 289
TYR D 327
LEU D 330
ILE D 341
MET D 364
HIS D 449
TYR D 473
 None
PLB  D 701 (-3.3A)
PLB  D 701 ( 3.9A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.8A)
None
None
 0.85A 6md4A-3dzuD:
36.8		 6md4A-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 PHE D 363
TYR D 327
LEU D 330
ILE D 341
HIS D 449
TYR D 473
 None
None
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
None
None
 1.49A 6md4A-3dzuD:
36.8		 6md4A-3dzuD:
100.00