SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'PJZ'


List of Similar Pattern of Amino Acids


Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_0
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
4qa8 PUTATIVE LIPOPROTEIN
LPRF

(Mycobacterium
bovis)
6 / 12 THR A 134
VAL A 141
SER A 142
GLY A 104
THR A 131
ALA A 146
PJZ  A 301 ( 4.4A)
None
None
None
None
None
1.38A 1jg4A-4qa8A:
undetectable
1jg4A-4qa8A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)
4qa8 PUTATIVE LIPOPROTEIN
LPRF

(Mycobacterium
bovis)
3 / 3 PRO A 152
VAL A  77
HIS A  76
PJZ  A 301 (-4.8A)
None
None
0.77A 4pevC-4qa8A:
undetectable
4pevC-4qa8A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_B_010B607_0
(HNL ISOENZYME 5)
4qa8 PUTATIVE LIPOPROTEIN
LPRF

(Mycobacterium
bovis)
5 / 10 ALA A 106
ALA A  94
VAL A  92
LEU A 156
TYR A 150
PJZ  A 301 (-3.3A)
PJZ  A 301 ( 4.0A)
None
None
PJZ  A 301 (-3.8A)
1.27A 5eb5B-4qa8A:
undetectable
5eb5B-4qa8A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)
4qa8 PUTATIVE LIPOPROTEIN
LPRF

(Mycobacterium
bovis)
4 / 7 ILE A 154
ILE A 197
ILE A 245
LEU A 204
None
None
PJZ  A 301 ( 4.2A)
None
0.73A 5fukA-4qa8A:
undetectable
5fukB-4qa8A:
undetectable
5fukA-4qa8A:
24.07
5fukB-4qa8A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MRA_B_DM2B204_1
(SORCIN)
4qa8 PUTATIVE LIPOPROTEIN
LPRF

(Mycobacterium
bovis)
4 / 6 THR A 134
ARG A 136
ASP A 139
GLY A 138
PJZ  A 301 ( 4.4A)
None
None
None
1.21A 5mraA-4qa8A:
undetectable
5mraB-4qa8A:
undetectable
5mraA-4qa8A:
20.89
5mraB-4qa8A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)
4qa8 PUTATIVE LIPOPROTEIN
LPRF

(Mycobacterium
bovis)
5 / 9 VAL A  75
ILE A 245
LEU A 247
ILE A 200
ALA A 106
None
PJZ  A 301 ( 4.2A)
None
None
PJZ  A 301 (-3.3A)
1.00A 5nunA-4qa8A:
undetectable
5nunA-4qa8A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)
4qa8 PUTATIVE LIPOPROTEIN
LPRF

(Mycobacterium
bovis)
5 / 12 GLY A 251
ALA A 252
ILE A 155
LEU A 156
PRO A 152
None
None
PJZ  A 301 (-4.4A)
None
PJZ  A 301 (-4.8A)
1.13A 6b3aA-4qa8A:
undetectable
6b3aA-4qa8A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3B_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)
4qa8 PUTATIVE LIPOPROTEIN
LPRF

(Mycobacterium
bovis)
5 / 12 GLY A 251
ALA A 252
ILE A 155
LEU A 156
PRO A 152
None
None
PJZ  A 301 (-4.4A)
None
PJZ  A 301 (-4.8A)
1.15A 6b3bA-4qa8A:
undetectable
6b3bA-4qa8A:
18.44