SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'PIS'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E7C_A_HLTA4001_1 (SERUM ALBUMIN)	5hc8	PRENYLTRANSFERENCE FOR PROTEIN (Lavandula lanata)	4 / 5	ARG A 79 LYS A 83 ALA A 82 GLY A 77	PIS A 402 (-4.4A) None None PIS A 402 (-3.2A)	1.15A	1e7cA-5hc8A: undetectable	1e7cA-5hc8A: 18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1H9Z_A_RWFA3001_1 (SERUM ALBUMIN)	5hc8	PRENYLTRANSFERENCE FOR PROTEIN (Lavandula lanata)	5 / 11	ALA A 119 LEU A 120 LEU A 135 HIS A 93 SER A 128	61G A 403 (-4.8A) None 61G A 403 ( 4.5A) PIS A 402 (-4.1A) None	1.01A	1h9zA-5hc8A: undetectable	1h9zA-5hc8A: 18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HA2_A_SWFA3001_1 (SERUM ALBUMIN)	5hc8	PRENYLTRANSFERENCE FOR PROTEIN (Lavandula lanata)	5 / 11	ALA A 119 LEU A 120 LEU A 135 HIS A 93 SER A 128	61G A 403 (-4.8A) None 61G A 403 ( 4.5A) PIS A 402 (-4.1A) None	1.07A	1ha2A-5hc8A: undetectable	1ha2A-5hc8A: 18.35