SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'PHH'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1g0n TRIHYDROXYNAPHTHALEN
E REDUCTASE
(Magnaporthe
grisea) 		5 / 12 TYR A 178
ILE A  41
GLY A 163
SER A 181
GLY A 209
 PHH  A 402 ( 4.0A)
NDP  A 400 (-4.1A)
None
None
PHH  A 402 (-4.3A)
 0.97A 1kiaA-1g0nA:
6.3		 1kiaA-1g0nA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1g0n TRIHYDROXYNAPHTHALEN
E REDUCTASE
(Magnaporthe
grisea) 		5 / 12 TYR A 178
ILE A  41
GLY A 163
SER A 181
GLY A 209
 PHH  A 402 ( 4.0A)
NDP  A 400 (-4.1A)
None
None
PHH  A 402 (-4.3A)
 0.98A 1nbhB-1g0nA:
6.6		 1nbhB-1g0nA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1g0n TRIHYDROXYNAPHTHALEN
E REDUCTASE
(Magnaporthe
grisea) 		5 / 12 TYR A 178
ILE A  41
GLY A 163
SER A 181
GLY A 209
 PHH  A 402 ( 4.0A)
NDP  A 400 (-4.1A)
None
None
PHH  A 402 (-4.3A)
 0.99A 1nbiA-1g0nA:
6.2		 1nbiA-1g0nA:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1g0n TRIHYDROXYNAPHTHALEN
E REDUCTASE
(Magnaporthe
grisea) 		5 / 12 TYR A 178
ILE A  41
GLY A 163
SER A 181
GLY A 209
 PHH  A 402 ( 4.0A)
NDP  A 400 (-4.1A)
None
None
PHH  A 402 (-4.3A)
 0.98A 1nbiB-1g0nA:
6.9		 1nbiB-1g0nA:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_C_DX2C270_1
(PTERIDINE REDUCTASE
1)		 1g0n TRIHYDROXYNAPHTHALEN
E REDUCTASE
(Magnaporthe
grisea) 		4 / 8 SER A 164
VAL A 249
LEU A 251
PRO A 252
 PHH  A 402 (-2.2A)
None
None
None
 0.81A 3jq7C-1g0nA:
30.5		 3jq7C-1g0nA:
28.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_2
(ADENOSINE KINASE)		 1g0n TRIHYDROXYNAPHTHALEN
E REDUCTASE
(Magnaporthe
grisea) 		4 / 5 SER A 164
ILE A  41
TYR A 178
GLY A 209
 PHH  A 402 (-2.2A)
NDP  A 400 (-4.1A)
PHH  A 402 ( 4.0A)
PHH  A 402 (-4.3A)
 1.05A 3uboB-1g0nA:
6.6		 3uboB-1g0nA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HXY_B_ACAB502_1
(PLM1)		 1g0n TRIHYDROXYNAPHTHALEN
E REDUCTASE
(Magnaporthe
grisea) 		4 / 7 VAL A 118
SER A 164
TYR A 178
MET A 215
 None
PHH  A 402 (-2.2A)
PHH  A 402 ( 4.0A)
PHH  A 402 ( 3.3A)
 0.54A 4hxyB-1g0nA:
19.1		 4hxyB-1g0nA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW9_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 1g0n TRIHYDROXYNAPHTHALEN
E REDUCTASE
(Magnaporthe
grisea) 		5 / 8 THR A 166
GLY A 167
ALA A 169
GLY A 183
SER A 181
 PHH  A 402 (-3.4A)
None
None
None
None
 1.37A 5vw9A-1g0nA:
2.7		 5vw9A-1g0nA:
20.67