SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'PGW'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_2
(MINERALOCORTICOID
RECEPTOR)		 6cjq -
(-) 		4 / 4 LEU A  91
LEU A 100
SER A 105
LEU A  34
 None
None
None
PGW  A 505 ( 4.4A)
 1.18A 1ya3A-6cjqA:
undetectable		 1ya3A-6cjqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA502_0
(OXIDOREDUCTASE,
FMN-BINDING)		 6cjq -
(-) 		4 / 7 THR A  33
HIS A 149
LEU A 112
PHE A  96
 None
PGW  A 503 ( 4.9A)
PGW  A 505 ( 4.7A)
None
 1.19A 4awuA-6cjqA:
undetectable		 4awuA-6cjqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 6cjq -
(-) 		5 / 12 LEU A 112
CYH A 153
SER A 105
LEU A  93
THR A  33
 PGW  A 505 ( 4.7A)
None
None
None
None
 1.42A 4iarA-6cjqA:
4.3		 4iarA-6cjqA:
undetectable