SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'PGM'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1FK6_A_LNLA1201_1 (NON-SPECIFIC LIPID TRANSFER PROTEIN)	5lqv	NON-SPECIFIC LIPID-TRANSFER PROTEIN 2 (Lens culinaris)	5 / 12	ALA A 39 ARG A 45 ALA A 48 LEU A 52 ALA A 56	PGM A 101 ( 4.8A) None PGM A 101 ( 3.9A) PGM A 101 (-3.1A) PGM A 101 (-2.7A)	0.90A	1fk6A-5lqvA: 14.1	1fk6A-5lqvA: 58.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1FK6_A_LNLA1201_1 (NON-SPECIFIC LIPID TRANSFER PROTEIN)	5lqv	NON-SPECIFIC LIPID-TRANSFER PROTEIN 2 (Lens culinaris)	5 / 12	LEU A 35 ALA A 39 ALA A 48 LEU A 52 ALA A 56	PGM A 101 (-3.3A) PGM A 101 ( 4.8A) PGM A 101 ( 3.9A) PGM A 101 (-3.1A) PGM A 101 (-2.7A)	0.76A	1fk6A-5lqvA: 14.1	1fk6A-5lqvA: 58.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1FK6_A_LNLA1201_1 (NON-SPECIFIC LIPID TRANSFER PROTEIN)	5lqv	NON-SPECIFIC LIPID-TRANSFER PROTEIN 2 (Lens culinaris)	5 / 12	VAL A 32 LEU A 35 ALA A 39 ALA A 48 LEU A 52	None PGM A 101 (-3.3A) PGM A 101 ( 4.8A) PGM A 101 ( 3.9A) PGM A 101 (-3.1A)	0.75A	1fk6A-5lqvA: 14.1	1fk6A-5lqvA: 58.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IM2_A_BEZA401_0 (TWIN-ARGININE TRANSLOCATION PATHWAY SIGNAL)	5lqv	NON-SPECIFIC LIPID-TRANSFER PROTEIN 2 (Lens culinaris)	5 / 12	VAL A 76 ILE A 82 LEU A 70 LEU A 11 VAL A 32	None PGM A 101 (-3.4A) None PGM A 101 ( 4.4A) None	1.15A	5im2A-5lqvA: undetectable	5im2A-5lqvA: 13.33

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FK6_A_LNLA1201_1","NON-SPECIFIC LIPID TRANSFER PROTEIN","5lqv","NON-SPECIFIC LIPID-TRANSFER PROTEIN 2","Lens culinaris",5,"ALA A  39;ARG A  45;ALA A  48;LEU A  52;ALA A  56","PGM A 101 ( 4.8A);None;PGM A 101 ( 3.9A);PGM A 101 (-3.1A);PGM A 101 (-2.7A)","0.90A","1fk6A-5lqvA:14.1",null],["1FK6_A_LNLA1201_1","NON-SPECIFIC LIPID TRANSFER PROTEIN","5lqv","NON-SPECIFIC LIPID-TRANSFER PROTEIN 2","Lens culinaris",5,"LEU A  35;ALA A  39;ALA A  48;LEU A  52;ALA A  56","PGM A 101 (-3.3A);PGM A 101 ( 4.8A);PGM A 101 ( 3.9A);PGM A 101 (-3.1A);PGM A 101 (-2.7A)","0.76A","1fk6A-5lqvA:14.1","1fk6A-5lqvA:58.06"],["1FK6_A_LNLA1201_1","NON-SPECIFIC LIPID TRANSFER PROTEIN","5lqv","NON-SPECIFIC LIPID-TRANSFER PROTEIN 2","Lens culinaris",5,"VAL A  32;LEU A  35;ALA A  39;ALA A  48;LEU A  52","None;PGM A 101 (-3.3A);PGM A 101 ( 4.8A);PGM A 101 ( 3.9A);PGM A 101 (-3.1A)","0.75A","1fk6A-5lqvA:14.1","1fk6A-5lqvA:58.06"],["5IM2_A_BEZA401_0","TWIN-ARGININE TRANSLOCATION PATHWAY SIGNAL","5lqv","NON-SPECIFIC LIPID-TRANSFER PROTEIN 2","Lens culinaris",5,"VAL A  76;ILE A  82;LEU A  70;LEU A  11;VAL A  32","None;PGM A 101 (-3.4A);None;PGM A 101 ( 4.4A);None","1.15A","5im2A-5lqvA:undetectable","1fk6A-5lqvA:58.06"]]