SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'PER'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 8 GLY A 199
SER A 206
ILE A 129
ASP A 112
 None
PER  A 409 ( 4.1A)
None
None
 0.92A 1jg4A-1wx4A:
undetectable		 1jg4A-1wx4A:
22.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		8 / 11 HIS A  38
ILE A  42
HIS A  54
HIS A 190
ASN A 191
HIS A 194
VAL A 195
SER A 206
 CU  A 400 ( 3.3A)
None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
PER  A 409 ( 4.1A)
 0.25A 2zweA-1wx4A:
50.0
2zweB-1wx4A:
undetectable		 2zweA-1wx4A:
100.00
2zweB-1wx4A:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.00A 2zweA-1wx4A:
50.0
2zweB-1wx4A:
undetectable		 2zweA-1wx4A:
100.00
2zweB-1wx4A:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  63
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.50A 2zweA-1wx4A:
50.0
2zweB-1wx4A:
undetectable		 2zweA-1wx4A:
100.00
2zweB-1wx4A:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.32A 2zweA-1wx4A:
50.0
2zweB-1wx4A:
undetectable		 2zweA-1wx4A:
100.00
2zweB-1wx4A:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 ILE A  42
HIS A  54
HIS A 216
HIS A 194
SER A 206
 None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.4A)
CU  A 401 ( 3.2A)
PER  A 409 ( 4.1A)
 1.42A 2zweA-1wx4A:
50.0
2zweB-1wx4A:
undetectable		 2zweA-1wx4A:
100.00
2zweB-1wx4A:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		8 / 11 HIS A  38
ILE A  42
HIS A  54
HIS A 190
ASN A 191
HIS A 194
VAL A 195
SER A 206
 CU  A 400 ( 3.3A)
None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
PER  A 409 ( 4.1A)
 0.15A 2zwfA-1wx4A:
50.0
2zwfB-1wx4A:
undetectable		 2zwfA-1wx4A:
100.00
2zwfB-1wx4A:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 0.95A 2zwfA-1wx4A:
50.0
2zwfB-1wx4A:
undetectable		 2zwfA-1wx4A:
100.00
2zwfB-1wx4A:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  63
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.44A 2zwfA-1wx4A:
50.0
2zwfB-1wx4A:
undetectable		 2zwfA-1wx4A:
100.00
2zwfB-1wx4A:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.38A 2zwfA-1wx4A:
50.0
2zwfB-1wx4A:
undetectable		 2zwfA-1wx4A:
100.00
2zwfB-1wx4A:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		8 / 11 HIS A  38
ILE A  42
HIS A  54
HIS A 190
ASN A 191
HIS A 194
VAL A 195
SER A 206
 CU  A 400 ( 3.3A)
None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
PER  A 409 ( 4.1A)
 0.17A 2zwgA-1wx4A:
49.9
2zwgB-1wx4A:
undetectable		 2zwgA-1wx4A:
100.00
2zwgB-1wx4A:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 0.93A 2zwgA-1wx4A:
49.9
2zwgB-1wx4A:
undetectable		 2zwgA-1wx4A:
100.00
2zwgB-1wx4A:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  63
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.42A 2zwgA-1wx4A:
49.9
2zwgB-1wx4A:
undetectable		 2zwgA-1wx4A:
100.00
2zwgB-1wx4A:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.38A 2zwgA-1wx4A:
49.9
2zwgB-1wx4A:
undetectable		 2zwgA-1wx4A:
100.00
2zwgB-1wx4A:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 ILE A  42
HIS A  54
HIS A 216
HIS A 194
SER A 206
 None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.4A)
CU  A 401 ( 3.2A)
PER  A 409 ( 4.1A)
 1.40A 2zwgA-1wx4A:
49.9
2zwgB-1wx4A:
undetectable		 2zwgA-1wx4A:
100.00
2zwgB-1wx4A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_A_MMSA514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		6 / 10 HIS A  38
HIS A  54
HIS A 190
ASN A 191
HIS A 194
SER A 206
 CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
PER  A 409 ( 4.1A)
 0.47A 5m8nA-1wx4A:
29.4		 5m8nA-1wx4A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_A_MMSA514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 10 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.24A 5m8nA-1wx4A:
29.4		 5m8nA-1wx4A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_B_MMSB515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		6 / 10 HIS A  38
HIS A  54
HIS A 190
ASN A 191
HIS A 194
SER A 206
 CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
PER  A 409 ( 4.1A)
 0.42A 5m8nB-1wx4A:
29.3		 5m8nB-1wx4A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_B_MMSB515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 10 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.27A 5m8nB-1wx4A:
29.3		 5m8nB-1wx4A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		6 / 9 HIS A  38
HIS A  54
HIS A 190
ASN A 191
HIS A 194
SER A 206
 CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
PER  A 409 ( 4.1A)
 0.48A 5m8nC-1wx4A:
29.2		 5m8nC-1wx4A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 9 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.21A 5m8nC-1wx4A:
29.2		 5m8nC-1wx4A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_D_MMSD515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 9 HIS A  54
HIS A 190
ASN A 191
HIS A 194
SER A 206
 CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
PER  A 409 ( 4.1A)
 0.42A 5m8nD-1wx4A:
28.9		 5m8nD-1wx4A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 7 HIS A  54
HIS A 190
ASN A 191
HIS A 194
SER A 206
 CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
PER  A 409 ( 4.1A)
 0.30A 5m8rA-1wx4A:
29.4		 5m8rA-1wx4A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 7 HIS A 190
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.04A 5m8rA-1wx4A:
29.4		 5m8rA-1wx4A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 8 HIS A  54
HIS A 190
ASN A 191
HIS A 194
SER A 206
 CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
PER  A 409 ( 4.1A)
 0.35A 5m8rB-1wx4A:
29.4		 5m8rB-1wx4A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 8 HIS A  54
HIS A 190
ASN A 191
HIS A 194
SER A 206
 CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
PER  A 409 ( 4.1A)
 0.34A 5m8rC-1wx4A:
29.4		 5m8rC-1wx4A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 8 HIS A  54
HIS A 190
ASN A 191
HIS A 194
SER A 206
 CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
PER  A 409 ( 4.1A)
 0.36A 5m8rD-1wx4A:
29.4		 5m8rD-1wx4A:
22.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		8 / 11 HIS A  38
ILE A  42
HIS A  54
HIS A 190
ASN A 191
HIS A 194
VAL A 195
SER A 206
 CU  A 400 ( 3.3A)
None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
PER  A 409 ( 4.1A)
 0.31A 5z0fA-1wx4A:
49.3
5z0fB-1wx4A:
undetectable		 5z0fA-1wx4A:
100.00
5z0fB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 0.97A 5z0fA-1wx4A:
49.3
5z0fB-1wx4A:
undetectable		 5z0fA-1wx4A:
100.00
5z0fB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  63
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.46A 5z0fA-1wx4A:
49.3
5z0fB-1wx4A:
undetectable		 5z0fA-1wx4A:
100.00
5z0fB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.40A 5z0fA-1wx4A:
49.3
5z0fB-1wx4A:
undetectable		 5z0fA-1wx4A:
100.00
5z0fB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 ILE A  42
HIS A  54
HIS A 216
HIS A 194
SER A 206
 None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.4A)
CU  A 401 ( 3.2A)
PER  A 409 ( 4.1A)
 1.48A 5z0fA-1wx4A:
49.3
5z0fB-1wx4A:
undetectable		 5z0fA-1wx4A:
100.00
5z0fB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		8 / 11 HIS A  38
ILE A  42
HIS A  54
HIS A 190
ASN A 191
HIS A 194
VAL A 195
SER A 206
 CU  A 400 ( 3.3A)
None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
PER  A 409 ( 4.1A)
 0.33A 5z0gA-1wx4A:
49.8
5z0gB-1wx4A:
undetectable		 5z0gA-1wx4A:
100.00
5z0gB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 0.99A 5z0gA-1wx4A:
49.8
5z0gB-1wx4A:
undetectable		 5z0gA-1wx4A:
100.00
5z0gB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  63
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.47A 5z0gA-1wx4A:
49.8
5z0gB-1wx4A:
undetectable		 5z0gA-1wx4A:
100.00
5z0gB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.39A 5z0gA-1wx4A:
49.8
5z0gB-1wx4A:
undetectable		 5z0gA-1wx4A:
100.00
5z0gB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		8 / 11 HIS A  38
ILE A  42
HIS A  54
HIS A 190
ASN A 191
HIS A 194
VAL A 195
SER A 206
 CU  A 400 ( 3.3A)
None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
PER  A 409 ( 4.1A)
 0.16A 5z0hA-1wx4A:
49.8
5z0hB-1wx4A:
undetectable		 5z0hA-1wx4A:
100.00
5z0hB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 0.96A 5z0hA-1wx4A:
49.8
5z0hB-1wx4A:
undetectable		 5z0hA-1wx4A:
100.00
5z0hB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  63
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.41A 5z0hA-1wx4A:
49.8
5z0hB-1wx4A:
undetectable		 5z0hA-1wx4A:
100.00
5z0hB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.40A 5z0hA-1wx4A:
49.8
5z0hB-1wx4A:
undetectable		 5z0hA-1wx4A:
100.00
5z0hB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		8 / 11 HIS A  38
ILE A  42
HIS A  54
HIS A 190
ASN A 191
HIS A 194
VAL A 195
SER A 206
 CU  A 400 ( 3.3A)
None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
PER  A 409 ( 4.1A)
 0.30A 5z0iA-1wx4A:
49.9
5z0iB-1wx4A:
undetectable		 5z0iA-1wx4A:
100.00
5z0iB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 0.96A 5z0iA-1wx4A:
49.9
5z0iB-1wx4A:
undetectable		 5z0iA-1wx4A:
100.00
5z0iB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  63
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.45A 5z0iA-1wx4A:
49.9
5z0iB-1wx4A:
undetectable		 5z0iA-1wx4A:
100.00
5z0iB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.39A 5z0iA-1wx4A:
49.9
5z0iB-1wx4A:
undetectable		 5z0iA-1wx4A:
100.00
5z0iB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 ILE A  42
HIS A  54
HIS A 216
HIS A 194
SER A 206
 None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.4A)
CU  A 401 ( 3.2A)
PER  A 409 ( 4.1A)
 1.47A 5z0iA-1wx4A:
49.9
5z0iB-1wx4A:
undetectable		 5z0iA-1wx4A:
100.00
5z0iB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		8 / 11 HIS A  38
ILE A  42
HIS A  54
HIS A 190
ASN A 191
HIS A 194
VAL A 195
SER A 206
 CU  A 400 ( 3.3A)
None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
PER  A 409 ( 4.1A)
 0.15A 5z0jA-1wx4A:
49.6
5z0jB-1wx4A:
undetectable		 5z0jA-1wx4A:
100.00
5z0jB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 0.97A 5z0jA-1wx4A:
49.6
5z0jB-1wx4A:
undetectable		 5z0jA-1wx4A:
100.00
5z0jB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  63
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.46A 5z0jA-1wx4A:
49.6
5z0jB-1wx4A:
undetectable		 5z0jA-1wx4A:
100.00
5z0jB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.36A 5z0jA-1wx4A:
49.6
5z0jB-1wx4A:
undetectable		 5z0jA-1wx4A:
100.00
5z0jB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		8 / 11 HIS A  38
ILE A  42
HIS A  54
HIS A 190
ASN A 191
HIS A 194
VAL A 195
SER A 206
 CU  A 400 ( 3.3A)
None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
PER  A 409 ( 4.1A)
 0.18A 5z0kA-1wx4A:
49.8
5z0kB-1wx4A:
undetectable		 5z0kA-1wx4A:
100.00
5z0kB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 0.99A 5z0kA-1wx4A:
49.8
5z0kB-1wx4A:
undetectable		 5z0kA-1wx4A:
100.00
5z0kB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  63
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.45A 5z0kA-1wx4A:
49.8
5z0kB-1wx4A:
undetectable		 5z0kA-1wx4A:
100.00
5z0kB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.35A 5z0kA-1wx4A:
49.8
5z0kB-1wx4A:
undetectable		 5z0kA-1wx4A:
100.00
5z0kB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		8 / 11 HIS A  38
ILE A  42
HIS A  54
HIS A 190
ASN A 191
HIS A 194
VAL A 195
SER A 206
 CU  A 400 ( 3.3A)
None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
PER  A 409 ( 4.1A)
 0.18A 5z0lA-1wx4A:
49.8
5z0lB-1wx4A:
undetectable		 5z0lA-1wx4A:
100.00
5z0lB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 0.97A 5z0lA-1wx4A:
49.8
5z0lB-1wx4A:
undetectable		 5z0lA-1wx4A:
100.00
5z0lB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  63
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.41A 5z0lA-1wx4A:
49.8
5z0lB-1wx4A:
undetectable		 5z0lA-1wx4A:
100.00
5z0lB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.40A 5z0lA-1wx4A:
49.8
5z0lB-1wx4A:
undetectable		 5z0lA-1wx4A:
100.00
5z0lB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		6 / 11 HIS A  38
HIS A  63
HIS A 190
HIS A 194
VAL A 195
SER A 206
 CU  A 400 ( 3.3A)
CU  A 400 ( 3.5A)
CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
None
PER  A 409 ( 4.1A)
 1.49A 5z0mA-1wx4A:
49.7
5z0mB-1wx4A:
undetectable		 5z0mA-1wx4A:
98.75
5z0mB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		8 / 11 HIS A  38
ILE A  42
HIS A  54
HIS A 190
ASN A 191
HIS A 194
VAL A 195
SER A 206
 CU  A 400 ( 3.3A)
None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
PER  A 409 ( 4.1A)
 0.25A 5z0mA-1wx4A:
49.7
5z0mB-1wx4A:
undetectable		 5z0mA-1wx4A:
98.75
5z0mB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 0.93A 5z0mA-1wx4A:
49.7
5z0mB-1wx4A:
undetectable		 5z0mA-1wx4A:
98.75
5z0mB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  63
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.36A 5z0mA-1wx4A:
49.7
5z0mB-1wx4A:
undetectable		 5z0mA-1wx4A:
98.75
5z0mB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.48A 5z0mA-1wx4A:
49.7
5z0mB-1wx4A:
undetectable		 5z0mA-1wx4A:
98.75
5z0mB-1wx4A:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 5 HIS A 190
HIS A 194
PHE A 212
HIS A 215
HIS A 216
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
PER  A 409 (-4.9A)
None
CU  A 401 ( 3.4A)
 0.33A 5zrdB-1wx4A:
3.7		 5zrdB-1wx4A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 5 HIS A  38
HIS A  54
HIS A  63
PHE A 212
 CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.5A)
PER  A 409 (-4.9A)
 0.36A 5zrdB-1wx4A:
3.7		 5zrdB-1wx4A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 5 HIS A  38
HIS A  54
HIS A  63
PHE A 212
 CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.5A)
PER  A 409 (-4.9A)
 0.30A 5zrdC-1wx4A:
3.3		 5zrdC-1wx4A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 5 HIS A  38
HIS A  54
HIS A  63
PHE A 212
 CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.5A)
PER  A 409 (-4.9A)
 0.40A 5zrdD-1wx4A:
4.6		 5zrdD-1wx4A:
21.17