SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'PEP'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEH_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 2nxg 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Aquifex
aeolicus) 		5 / 10 ASP A1182
ASN A1122
ILE A1097
GLU A1222
GLY A1009
 None
None
None
PEP  A1268 ( 4.4A)
None
 1.20A 1mehA-2nxgA:
11.0		 1mehA-2nxgA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVT_A_PRLA311_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 5uxn PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Pseudomonas
aeruginosa) 		4 / 8 LEU A 237
GLU A 241
TRP A 263
ILE A 136
 None
None
PEP  A 504 ( 4.8A)
None
 1.05A 1qvtA-5uxnA:
0.7		 1qvtA-5uxnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1qr7 PHENYLALANINE-REGULA
TED
3-DEOXY-D-ARABINO-HE
PTULOSONATE-7-PHOSPH
ATE SYNTHASE
(Escherichia
coli) 		4 / 6 VAL A 262
ILE A 297
TRP A 159
TYR A  94
 None
None
None
PEP  A1352 (-4.3A)
 0.96A 1s9qA-1qr7A:
undetectable		 1s9qA-1qr7A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1vs1 3-DEOXY-7-PHOSPHOHEP
TULONATE SYNTHASE
(Aeropyrum
pernix) 		4 / 7 ARG A 130
ARG A 181
GLN A 126
GLU A 108
 PEP  A 302 (-3.4A)
PEP  A 302 (-3.8A)
PEP  A 302 (-3.7A)
PEP  A 302 ( 4.3A)
 1.32A 2c8aA-1vs1A:
undetectable		 2c8aA-1vs1A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_B_ADNB1502_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 7 ARG A 136
TRP A 290
PRO A 144
ALA A 142
 PEP  A 502 (-2.7A)
PEP  A 502 (-4.7A)
None
None
 1.45A 2ejgB-5hucA:
undetectable		 2ejgB-5hucA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		 1qr7 PHENYLALANINE-REGULA
TED
3-DEOXY-D-ARABINO-HE
PTULOSONATE-7-PHOSPH
ATE SYNTHASE
(Escherichia
coli) 		4 / 8 SER A 271
GLN A 278
VAL A  57
ARG A  92
 None
None
None
PEP  A1352 (-3.2A)
 1.10A 3b9lA-1qr7A:
undetectable		 3b9lA-1qr7A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQZ_A_LQZA586_1
(SERUM ALBUMIN)		 2nxg 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Aquifex
aeolicus) 		4 / 6 ARG A1154
ASP A1182
LYS A1124
LYS A1041
 PEP  A1268 (-3.7A)
None
PEP  A1268 (-2.6A)
PEP  A1268 (-3.3A)
 1.44A 3jqzA-2nxgA:
0.0		 3jqzA-2nxgA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 9 TYR A 329
GLY A 297
VAL A 345
GLN A 374
GLY A 292
 None
None
None
None
PEP  A 502 (-3.2A)
 1.27A 3kmoA-5hucA:
undetectable		 3kmoA-5hucA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_B_ACTB901_0
(PYRANOSE 2-OXIDASE)		 1g7u 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Escherichia
coli) 		4 / 6 SER A  57
GLN A 113
PHE A 237
HIS A 202
 None
None
None
PEP  A 300 (-3.9A)
 1.46A 3lskB-1g7uA:
0.4		 3lskB-1g7uA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_B_ACTB901_0
(PYRANOSE 2-OXIDASE)		 2nxg 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Aquifex
aeolicus) 		4 / 6 SER A1043
GLN A1099
PHE A1220
HIS A1185
 PEP  A1268 (-3.6A)
PEP  A1268 (-4.0A)
PEP  A1268 (-4.6A)
PEP  A1268 (-4.1A)
 1.26A 3lskB-2nxgA:
undetectable		 3lskB-2nxgA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_D_ACTD901_0
(PYRANOSE 2-OXIDASE)		 1g7u 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Escherichia
coli) 		4 / 6 SER A  57
GLN A 113
PHE A 237
HIS A 202
 None
None
None
PEP  A 300 (-3.9A)
 1.45A 3lskD-1g7uA:
0.0		 3lskD-1g7uA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_D_ACTD901_0
(PYRANOSE 2-OXIDASE)		 2nxg 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Aquifex
aeolicus) 		4 / 6 SER A1043
GLN A1099
PHE A1220
HIS A1185
 PEP  A1268 (-3.6A)
PEP  A1268 (-4.0A)
PEP  A1268 (-4.6A)
PEP  A1268 (-4.1A)
 1.27A 3lskD-2nxgA:
undetectable		 3lskD-2nxgA:
18.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PP7_B_SVRB499_1
(PYRUVATE KINASE)		 4hyv PYRUVATE KINASE 1
(Trypanosoma
brucei) 		10 / 10 THR A  27
PRO A  30
ARG A  50
ASN A  52
HIS A  55
GLY A  56
TYR A  60
GLY A 332
ALA A 335
LYS A 336
 None
None
PEP  A1003 (-3.8A)
K  A1002 (-3.3A)
None
None
None
None
None
None
 0.48A 3pp7B-4hyvA:
67.4		 3pp7B-4hyvA:
74.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 1rzm PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Thermotoga
maritima) 		5 / 11 ILE A 233
ILE A 224
GLU A 164
PRO A 203
VAL A 162
 None
None
PEP  A8002 ( 4.8A)
None
None
 1.11A 3tmzA-1rzmA:
undetectable		 3tmzA-1rzmA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_1
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 4hyv PYRUVATE KINASE 1
(Trypanosoma
brucei) 		6 / 12 LEU A 198
ILE A 209
ASN A  52
ASP A  84
GLY A  87
GLY A 264
 None
None
K  A1002 (-3.3A)
K  A1002 (-3.4A)
None
PEP  A1003 (-3.3A)
 1.35A 4an2A-4hyvA:
undetectable		 4an2A-4hyvA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1vs1 3-DEOXY-7-PHOSPHOHEP
TULONATE SYNTHASE
(Aeropyrum
pernix) 		4 / 6 GLU A 171
ILE A 168
GLU A 108
VAL A 118
 None
None
PEP  A 302 ( 4.3A)
None
 1.05A 4ejwB-1vs1A:
undetectable		 4ejwB-1vs1A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4z17 ENOLASE
(Chloroflexus
aurantiacus) 		5 / 11 SER A 368
GLN A 341
ASP A 313
ASN A 149
ASP A 243
 PEP  A 502 (-4.0A)
None
MG  A 501 (-3.3A)
None
MG  A 501 ( 2.5A)
 1.44A 4fevE-4z17A:
undetectable		 4fevE-4z17A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_1
(METHYLTRANSFERASE
NSUN4)		 5uxn PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Pseudomonas
aeruginosa) 		3 / 3 ASP A 349
ARG A 320
ASP A 424
 None
PEP  A 504 (-3.9A)
CO  A 503 (-3.4A)
 0.85A 4fp9D-5uxnA:
undetectable		 4fp9D-5uxnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_A_SASA806_1
(SEPIAPTERIN
REDUCTASE)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 SER A 285
TYR A 264
GLN A 140
ALA A 142
GLY A 292
 None
None
None
None
PEP  A 502 (-3.2A)
 0.95A 4j7xA-5hucA:
undetectable		 4j7xA-5hucA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_A_SASA806_1
(SEPIAPTERIN
REDUCTASE)		 5uxn PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Pseudomonas
aeruginosa) 		5 / 12 SER A 258
TYR A 240
GLN A 112
ALA A 114
GLY A 265
 None
None
PEP  A 504 ( 4.8A)
None
PEP  A 504 (-3.3A)
 0.97A 4j7xA-5uxnA:
undetectable		 4j7xA-5uxnA:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 SER A 285
TYR A 264
GLN A 140
ALA A 142
GLY A 292
 None
None
None
None
PEP  A 502 (-3.2A)
 0.97A 4j7xB-5hucA:
undetectable		 4j7xB-5hucA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 5uxn PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Pseudomonas
aeruginosa) 		5 / 12 SER A 258
TYR A 240
GLN A 112
ALA A 114
GLY A 265
 None
None
PEP  A 504 ( 4.8A)
None
PEP  A 504 (-3.3A)
 0.98A 4j7xB-5uxnA:
undetectable		 4j7xB-5uxnA:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOW_A_CFXA204_1
(UNCHARACTERIZED
PROTEIN)		 5boe ENOLASE
(Staphylococcus
aureus) 		5 / 12 GLY A 396
ASN A 150
MET A 149
SER A 370
LEU A 341
 None
None
None
PEP  A 501 ( 4.7A)
None
 1.25A 4kowA-5boeA:
undetectable		 4kowA-5boeA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOW_A_CFXA204_1
(UNCHARACTERIZED
PROTEIN)		 5j04 ENOLASE
(Synechococcus
elongatus) 		5 / 12 GLY A 392
ASN A 152
MET A 151
SER A 366
LEU A 337
 None
None
None
PEP  A 501 ( 4.5A)
None
 1.14A 4kowA-5j04A:
undetectable		 4kowA-5j04A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_C_3CJC607_1
(LACTOPEROXIDASE)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 6 ASP A 376
HIS A 419
ARG A 136
ARG A 392
 PEP  A 502 ( 4.8A)
None
PEP  A 502 (-2.7A)
MN  A 501 ( 4.3A)
 1.49A 4qyqC-5hucA:
undetectable		 4qyqC-5hucA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB102_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 5boe ENOLASE
(Staphylococcus
aureus) 		3 / 3 LYS A 105
ARG A 372
VAL A 344
 None
PEP  A 501 (-3.7A)
None
 1.07A 4x3uA-5boeA:
undetectable
4x3uB-5boeA:
undetectable		 4x3uA-5boeA:
11.20
4x3uB-5boeA:
11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)		 2nxg 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Aquifex
aeolicus) 		3 / 3 LYS A1041
ILE A1007
ILE A1180
 PEP  A1268 (-3.3A)
None
None
 0.57A 4y0qA-2nxgA:
undetectable		 4y0qA-2nxgA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 1g7u 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Escherichia
coli) 		5 / 9 GLY A  23
LEU A  21
GLN A 205
LEU A 255
LEU A 260
 None
None
PEP  A 300 ( 3.8A)
None
None
 1.45A 5fhzB-1g7uA:
undetectable		 5fhzB-1g7uA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_D_READ602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 1vs1 3-DEOXY-7-PHOSPHOHEP
TULONATE SYNTHASE
(Aeropyrum
pernix) 		5 / 12 GLU A 171
GLY A 142
ARG A 143
GLU A 108
LEU A 137
 None
None
None
PEP  A 302 ( 4.3A)
None
 1.48A 5fhzD-1vs1A:
undetectable		 5fhzD-1vs1A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_E_SAME301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 4hyv PYRUVATE KINASE 1
(Trypanosoma
brucei) 		5 / 12 ALA A 296
SER A 302
THR A 310
GLU A 333
SER A 331
 PEP  A1003 ( 3.9A)
None
None
None
PEP  A1003 ( 4.9A)
 1.20A 5hfjE-4hyvA:
undetectable		 5hfjE-4hyvA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPW_C_3CJC609_1
(LACTOPEROXIDASE)		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 6 ASP A 376
HIS A 419
ARG A 136
ARG A 392
 PEP  A 502 ( 4.8A)
None
PEP  A 502 (-2.7A)
MN  A 501 ( 4.3A)
 1.49A 5hpwC-5hucA:
undetectable		 5hpwC-5hucA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		 2nxg 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Aquifex
aeolicus) 		4 / 7 SER A1043
ASP A1081
PRO A1101
SER A1232
 PEP  A1268 (-3.6A)
PEP  A1268 ( 4.5A)
PEP  A1268 (-4.0A)
None
 1.20A 5l1fC-2nxgA:
undetectable		 5l1fC-2nxgA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA607_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 1rzm PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Thermotoga
maritima) 		4 / 4 GLY A 274
ARG A 237
ASN A 248
LEU A 250
 None
PEP  A8002 (-3.9A)
None
None
 1.18A 6b58A-1rzmA:
undetectable		 6b58A-1rzmA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPL_B_PA1B605_1
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 1rzm PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Thermotoga
maritima) 		3 / 3 ARG A 247
ARG A 126
ARG A 133
 None
PEP  A8002 (-3.2A)
E4P  A8003 (-4.1A)
 1.08A 6bplA-1rzmA:
undetectable
6bplB-1rzmA:
0.8		 6bplA-1rzmA:
16.85
6bplB-1rzmA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPL_B_PA1B605_1
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 1rzm PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Thermotoga
maritima) 		3 / 3 ARG A 247
ARG A 126
ARG A 237
 None
PEP  A8002 (-3.2A)
PEP  A8002 (-3.9A)
 1.09A 6bplA-1rzmA:
undetectable
6bplB-1rzmA:
0.8		 6bplA-1rzmA:
16.85
6bplB-1rzmA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 5uxn PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE
(Pseudomonas
aeruginosa) 		4 / 8 ILE A 356
THR A 355
ARG A 320
SER A 118
 None
None
PEP  A 504 (-3.9A)
PO4  A 502 (-2.4A)
 1.03A 6c06C-5uxnA:
undetectable		 6c06C-5uxnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE
(Corynebacterium
glutamicum) 		3 / 3 ARG A 145
LYS A 143
ARG A 181
 None
PEP  A 502 ( 3.8A)
MPD  A 504 ( 4.9A)
 1.24A 6c06D-5hucA:
undetectable		 6c06D-5hucA:
undetectable