SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'PEO'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 1otw COENZYME PQQ
SYNTHESIS PROTEIN C
(Klebsiella
pneumoniae) 		5 / 12 THR A 146
ALA A 150
ILE A  43
PHE A 149
LEU A 218
 PQQ  A 500 (-3.7A)
PEO  A 600 (-3.1A)
None
None
None
 1.23A 1eiiA-1otwA:
undetectable		 1eiiA-1otwA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_B_D16B568_1
(THYMIDYLATE SYNTHASE)		 5nue MALATE DEHYDROGENASE
1, CYTOPLASMIC
(Arabidopsis
thaliana) 		5 / 12 LEU A 220
LEU A 165
GLY A 166
VAL A 182
ALA A 199
 None
None
PEO  A 406 (-3.5A)
None
None
 1.09A 2kceB-5nueA:
undetectable		 2kceB-5nueA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 3lm4 CATECHOL
2,3-DIOXYGENASE
(Rhodococcus
jostii) 		5 / 11 HIS A 249
HIS A 217
ASN A 157
HIS A 155
VAL A 202
 HPX  A 406 (-3.4A)
FE  A 400 ( 3.4A)
PEO  A 401 ( 4.1A)
FE  A 400 ( 3.5A)
None
 1.24A 2zweA-3lm4A:
undetectable
2zweB-3lm4A:
undetectable		 2zweA-3lm4A:
22.54
2zweB-3lm4A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 3lm4 CATECHOL
2,3-DIOXYGENASE
(Rhodococcus
jostii) 		5 / 11 HIS A 249
HIS A 217
ASN A 157
HIS A 155
VAL A 202
 HPX  A 406 (-3.4A)
FE  A 400 ( 3.4A)
PEO  A 401 ( 4.1A)
FE  A 400 ( 3.5A)
None
 1.23A 2zwfA-3lm4A:
undetectable
2zwfB-3lm4A:
undetectable		 2zwfA-3lm4A:
22.54
2zwfB-3lm4A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 3lm4 CATECHOL
2,3-DIOXYGENASE
(Rhodococcus
jostii) 		5 / 11 HIS A 249
HIS A 217
ASN A 157
HIS A 155
VAL A 202
 HPX  A 406 (-3.4A)
FE  A 400 ( 3.4A)
PEO  A 401 ( 4.1A)
FE  A 400 ( 3.5A)
None
 1.24A 2zwgA-3lm4A:
undetectable
2zwgB-3lm4A:
undetectable		 2zwgA-3lm4A:
22.54
2zwgB-3lm4A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IR0_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 3lm4 CATECHOL
2,3-DIOXYGENASE
(Rhodococcus
jostii) 		5 / 11 HIS A 217
TYR A 258
GLU A 268
HIS A 155
ALA A 203
 FE  A 400 ( 3.4A)
None
FE  A 400 (-2.7A)
FE  A 400 ( 3.5A)
PEO  A 401 ( 3.7A)
 0.60A 4ir0A-3lm4A:
7.6
4ir0B-3lm4A:
7.8		 4ir0A-3lm4A:
17.54
4ir0B-3lm4A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IR0_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 3lm4 CATECHOL
2,3-DIOXYGENASE
(Rhodococcus
jostii) 		5 / 11 HIS A 155
ALA A 203
HIS A 217
TYR A 258
GLU A 268
 FE  A 400 ( 3.5A)
PEO  A 401 ( 3.7A)
FE  A 400 ( 3.4A)
None
FE  A 400 (-2.7A)
 0.52A 4ir0A-3lm4A:
7.6
4ir0B-3lm4A:
7.8		 4ir0A-3lm4A:
17.54
4ir0B-3lm4A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD1_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 3lm4 CATECHOL
2,3-DIOXYGENASE
(Rhodococcus
jostii) 		5 / 12 HIS A 217
TYR A 258
GLU A 268
HIS A 155
ALA A 203
 FE  A 400 ( 3.4A)
None
FE  A 400 (-2.7A)
FE  A 400 ( 3.5A)
PEO  A 401 ( 3.7A)
 0.55A 4jd1A-3lm4A:
7.2
4jd1B-3lm4A:
7.6		 4jd1A-3lm4A:
17.54
4jd1B-3lm4A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD1_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 3lm4 CATECHOL
2,3-DIOXYGENASE
(Rhodococcus
jostii) 		5 / 12 HIS A 155
ALA A 203
HIS A 217
TYR A 258
GLU A 268
 FE  A 400 ( 3.5A)
PEO  A 401 ( 3.7A)
FE  A 400 ( 3.4A)
None
FE  A 400 (-2.7A)
 0.64A 4jd1A-3lm4A:
7.2
4jd1B-3lm4A:
7.6		 4jd1A-3lm4A:
17.54
4jd1B-3lm4A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH3_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		 3lm4 CATECHOL
2,3-DIOXYGENASE
(Rhodococcus
jostii) 		5 / 12 HIS A 217
TYR A 258
GLU A 268
HIS A 155
ALA A 203
 FE  A 400 ( 3.4A)
None
FE  A 400 (-2.7A)
FE  A 400 ( 3.5A)
PEO  A 401 ( 3.7A)
 0.52A 4jh3A-3lm4A:
7.3
4jh3B-3lm4A:
7.4		 4jh3A-3lm4A:
18.34
4jh3B-3lm4A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH3_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 3lm4 CATECHOL
2,3-DIOXYGENASE
(Rhodococcus
jostii) 		5 / 11 HIS A 155
ALA A 203
HIS A 217
TYR A 258
GLU A 268
 FE  A 400 ( 3.5A)
PEO  A 401 ( 3.7A)
FE  A 400 ( 3.4A)
None
FE  A 400 (-2.7A)
 0.49A 4jh3A-3lm4A:
7.3
4jh3B-3lm4A:
7.4		 4jh3A-3lm4A:
18.34
4jh3B-3lm4A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH4_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 3lm4 CATECHOL
2,3-DIOXYGENASE
(Rhodococcus
jostii) 		5 / 11 HIS A 217
TYR A 258
GLU A 268
HIS A 155
ALA A 203
 FE  A 400 ( 3.4A)
None
FE  A 400 (-2.7A)
FE  A 400 ( 3.5A)
PEO  A 401 ( 3.7A)
 0.44A 4jh4A-3lm4A:
7.4
4jh4B-3lm4A:
7.3		 4jh4A-3lm4A:
18.34
4jh4B-3lm4A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH4_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 3lm4 CATECHOL
2,3-DIOXYGENASE
(Rhodococcus
jostii) 		5 / 11 HIS A 155
ALA A 203
HIS A 217
TYR A 258
GLU A 268
 FE  A 400 ( 3.5A)
PEO  A 401 ( 3.7A)
FE  A 400 ( 3.4A)
None
FE  A 400 (-2.7A)
 0.47A 4jh4A-3lm4A:
7.4
4jh4B-3lm4A:
7.3		 4jh4A-3lm4A:
18.34
4jh4B-3lm4A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH5_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 3lm4 CATECHOL
2,3-DIOXYGENASE
(Rhodococcus
jostii) 		5 / 11 HIS A 217
TYR A 258
GLU A 268
HIS A 155
ALA A 203
 FE  A 400 ( 3.4A)
None
FE  A 400 (-2.7A)
FE  A 400 ( 3.5A)
PEO  A 401 ( 3.7A)
 0.47A 4jh5A-3lm4A:
7.4
4jh5B-3lm4A:
7.3		 4jh5A-3lm4A:
18.34
4jh5B-3lm4A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH5_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 3lm4 CATECHOL
2,3-DIOXYGENASE
(Rhodococcus
jostii) 		5 / 11 HIS A 155
ALA A 203
HIS A 217
TYR A 258
GLU A 268
 FE  A 400 ( 3.5A)
PEO  A 401 ( 3.7A)
FE  A 400 ( 3.4A)
None
FE  A 400 (-2.7A)
 0.50A 4jh5A-3lm4A:
7.4
4jh5B-3lm4A:
7.3		 4jh5A-3lm4A:
18.34
4jh5B-3lm4A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH6_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 3lm4 CATECHOL
2,3-DIOXYGENASE
(Rhodococcus
jostii) 		5 / 10 HIS A 217
TYR A 258
GLU A 268
HIS A 155
ALA A 203
 FE  A 400 ( 3.4A)
None
FE  A 400 (-2.7A)
FE  A 400 ( 3.5A)
PEO  A 401 ( 3.7A)
 0.51A 4jh6A-3lm4A:
7.4
4jh6B-3lm4A:
7.4		 4jh6A-3lm4A:
18.34
4jh6B-3lm4A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH6_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 3lm4 CATECHOL
2,3-DIOXYGENASE
(Rhodococcus
jostii) 		5 / 10 HIS A 155
ALA A 203
HIS A 217
TYR A 258
GLU A 268
 FE  A 400 ( 3.5A)
PEO  A 401 ( 3.7A)
FE  A 400 ( 3.4A)
None
FE  A 400 (-2.7A)
 0.52A 4jh6A-3lm4A:
7.4
4jh6B-3lm4A:
7.4		 4jh6A-3lm4A:
18.34
4jh6B-3lm4A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH8_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		 3lm4 CATECHOL
2,3-DIOXYGENASE
(Rhodococcus
jostii) 		5 / 10 HIS A 217
TYR A 258
GLU A 268
HIS A 155
ALA A 203
 FE  A 400 ( 3.4A)
None
FE  A 400 (-2.7A)
FE  A 400 ( 3.5A)
PEO  A 401 ( 3.7A)
 0.49A 4jh8A-3lm4A:
7.3
4jh8B-3lm4A:
7.3		 4jh8A-3lm4A:
18.34
4jh8B-3lm4A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH8_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 3lm4 CATECHOL
2,3-DIOXYGENASE
(Rhodococcus
jostii) 		5 / 10 HIS A 155
ALA A 203
HIS A 217
TYR A 258
GLU A 268
 FE  A 400 ( 3.5A)
PEO  A 401 ( 3.7A)
FE  A 400 ( 3.4A)
None
FE  A 400 (-2.7A)
 0.49A 4jh8A-3lm4A:
7.3
4jh8B-3lm4A:
7.3		 4jh8A-3lm4A:
18.34
4jh8B-3lm4A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7G_B_ACTB902_0
(3-HYDROXYPROLINE
DEHYDRATSE)		 2nli LACTATE OXIDASE
(Aerococcus
viridans) 		4 / 7 ASP A 296
SER A 297
HIS A 265
SER A 263
 FMN  A1375 (-2.8A)
FMN  A1375 (-4.0A)
PEO  A1377 ( 4.0A)
FMN  A1375 (-3.3A)
 0.83A 4k7gB-2nliA:
undetectable		 4k7gB-2nliA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 3n3b RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 2
SUBUNIT BETA
(Escherichia
coli) 		5 / 12 ILE B 138
LEU B  26
GLY B 196
SER B 159
ILE B 199
 None
None
None
PEO  B 322 (-3.1A)
None
 1.16A 4o1eA-3n3bB:
undetectable		 4o1eA-3n3bB:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 3n3b RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 2
SUBUNIT BETA
(Escherichia
coli) 		5 / 12 ILE B 138
LEU B  26
GLY B 196
SER B 159
ILE B 199
 None
None
None
PEO  B 322 (-3.1A)
None
 1.15A 4o1eB-3n3bB:
undetectable		 4o1eB-3n3bB:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		5 / 10 ALA A 105
GLY A  76
ALA A 104
HIS A  42
ILE A  80
 None
SO4  A1316 (-3.9A)
None
PEO  A1320 (-3.6A)
None
 1.17A 5eeuF-4uscA:
undetectable
5eeuG-4uscA:
undetectable		 5eeuF-4uscA:
13.01
5eeuG-4uscA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		5 / 10 ALA A 105
GLY A  76
ALA A 104
HIS A  42
ILE A  80
 None
SO4  A1316 (-3.9A)
None
PEO  A1320 (-3.6A)
None
 1.17A 5eevF-4uscA:
undetectable
5eevG-4uscA:
undetectable		 5eevF-4uscA:
13.01
5eevG-4uscA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		5 / 10 ALA A 105
GLY A  76
ALA A 104
HIS A  42
ILE A  80
 None
SO4  A1316 (-3.9A)
None
PEO  A1320 (-3.6A)
None
 1.17A 5eewF-4uscA:
undetectable
5eewG-4uscA:
undetectable		 5eewF-4uscA:
13.01
5eewG-4uscA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		5 / 10 ALA A 105
GLY A  76
ALA A 104
HIS A  42
ILE A  80
 None
SO4  A1316 (-3.9A)
None
PEO  A1320 (-3.6A)
None
 1.17A 5eexF-4uscA:
undetectable
5eexG-4uscA:
undetectable		 5eexF-4uscA:
13.01
5eexG-4uscA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		5 / 10 ALA A 105
GLY A  76
ALA A 104
HIS A  42
ILE A  80
 None
SO4  A1316 (-3.9A)
None
PEO  A1320 (-3.6A)
None
 1.17A 5eeyF-4uscA:
undetectable
5eeyG-4uscA:
undetectable		 5eeyF-4uscA:
13.01
5eeyG-4uscA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		5 / 10 ALA A 105
GLY A  76
ALA A 104
HIS A  42
ILE A  80
 None
SO4  A1316 (-3.9A)
None
PEO  A1320 (-3.6A)
None
 1.17A 5eezF-4uscA:
undetectable
5eezG-4uscA:
undetectable		 5eezF-4uscA:
13.01
5eezG-4uscA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		5 / 10 ALA A 105
GLY A  76
ALA A 104
HIS A  42
ILE A  80
 None
SO4  A1316 (-3.9A)
None
PEO  A1320 (-3.6A)
None
 1.18A 5ef0F-4uscA:
undetectable
5ef0G-4uscA:
undetectable		 5ef0F-4uscA:
13.01
5ef0G-4uscA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		5 / 10 ALA A 105
GLY A  76
ALA A 104
HIS A  42
ILE A  80
 None
SO4  A1316 (-3.9A)
None
PEO  A1320 (-3.6A)
None
 1.18A 5ef1F-4uscA:
undetectable
5ef1G-4uscA:
undetectable		 5ef1F-4uscA:
13.01
5ef1G-4uscA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		5 / 10 ALA A 105
GLY A  76
ALA A 104
HIS A  42
ILE A  80
 None
SO4  A1316 (-3.9A)
None
PEO  A1320 (-3.6A)
None
 1.18A 5ef2F-4uscA:
undetectable
5ef2G-4uscA:
undetectable		 5ef2F-4uscA:
13.01
5ef2G-4uscA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		5 / 10 ALA A 105
GLY A  76
ALA A 104
HIS A  42
ILE A  80
 None
SO4  A1316 (-3.9A)
None
PEO  A1320 (-3.6A)
None
 1.18A 5ef3F-4uscA:
undetectable
5ef3G-4uscA:
undetectable		 5ef3F-4uscA:
13.01
5ef3G-4uscA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3n3b RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 2
SUBUNIT BETA
(Escherichia
coli) 		3 / 3 ALA B 261
ASN B 264
LEU B 265
 None
PEO  B 322 ( 4.4A)
None
 0.37A 5i1nB-3n3bB:
undetectable		 5i1nB-3n3bB:
9.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3n3b RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 2
SUBUNIT BETA
(Escherichia
coli) 		3 / 3 ALA B 261
ASN B 264
LEU B 265
 None
PEO  B 322 ( 4.4A)
None
 0.44A 5i1oA-3n3bB:
undetectable		 5i1oA-3n3bB:
9.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 3lm4 CATECHOL
2,3-DIOXYGENASE
(Rhodococcus
jostii) 		5 / 11 HIS A 249
HIS A 217
ASN A 157
HIS A 155
VAL A 202
 HPX  A 406 (-3.4A)
FE  A 400 ( 3.4A)
PEO  A 401 ( 4.1A)
FE  A 400 ( 3.5A)
None
 1.20A 5z0fA-3lm4A:
undetectable
5z0fB-3lm4A:
undetectable		 5z0fA-3lm4A:
12.06
5z0fB-3lm4A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 3lm4 CATECHOL
2,3-DIOXYGENASE
(Rhodococcus
jostii) 		5 / 11 HIS A 249
HIS A 217
ASN A 157
HIS A 155
VAL A 202
 HPX  A 406 (-3.4A)
FE  A 400 ( 3.4A)
PEO  A 401 ( 4.1A)
FE  A 400 ( 3.5A)
None
 1.20A 5z0gA-3lm4A:
undetectable
5z0gB-3lm4A:
undetectable		 5z0gA-3lm4A:
12.06
5z0gB-3lm4A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 3lm4 CATECHOL
2,3-DIOXYGENASE
(Rhodococcus
jostii) 		5 / 11 HIS A 249
HIS A 217
ASN A 157
HIS A 155
VAL A 202
 HPX  A 406 (-3.4A)
FE  A 400 ( 3.4A)
PEO  A 401 ( 4.1A)
FE  A 400 ( 3.5A)
None
 1.22A 5z0hA-3lm4A:
undetectable
5z0hB-3lm4A:
undetectable		 5z0hA-3lm4A:
12.06
5z0hB-3lm4A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 3lm4 CATECHOL
2,3-DIOXYGENASE
(Rhodococcus
jostii) 		5 / 11 HIS A 249
HIS A 217
ASN A 157
HIS A 155
VAL A 202
 HPX  A 406 (-3.4A)
FE  A 400 ( 3.4A)
PEO  A 401 ( 4.1A)
FE  A 400 ( 3.5A)
None
 1.21A 5z0iA-3lm4A:
undetectable
5z0iB-3lm4A:
undetectable		 5z0iA-3lm4A:
12.06
5z0iB-3lm4A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 3lm4 CATECHOL
2,3-DIOXYGENASE
(Rhodococcus
jostii) 		5 / 11 HIS A 249
HIS A 217
ASN A 157
HIS A 155
VAL A 202
 HPX  A 406 (-3.4A)
FE  A 400 ( 3.4A)
PEO  A 401 ( 4.1A)
FE  A 400 ( 3.5A)
None
 1.22A 5z0jA-3lm4A:
undetectable
5z0jB-3lm4A:
undetectable		 5z0jA-3lm4A:
12.06
5z0jB-3lm4A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 3lm4 CATECHOL
2,3-DIOXYGENASE
(Rhodococcus
jostii) 		5 / 11 HIS A 249
HIS A 217
ASN A 157
HIS A 155
VAL A 202
 HPX  A 406 (-3.4A)
FE  A 400 ( 3.4A)
PEO  A 401 ( 4.1A)
FE  A 400 ( 3.5A)
None
 1.22A 5z0kA-3lm4A:
undetectable
5z0kB-3lm4A:
undetectable		 5z0kA-3lm4A:
12.06
5z0kB-3lm4A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 3lm4 CATECHOL
2,3-DIOXYGENASE
(Rhodococcus
jostii) 		5 / 11 HIS A 249
HIS A 217
ASN A 157
HIS A 155
VAL A 202
 HPX  A 406 (-3.4A)
FE  A 400 ( 3.4A)
PEO  A 401 ( 4.1A)
FE  A 400 ( 3.5A)
None
 1.21A 5z0lA-3lm4A:
undetectable
5z0lB-3lm4A:
undetectable		 5z0lA-3lm4A:
12.06
5z0lB-3lm4A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 3lm4 CATECHOL
2,3-DIOXYGENASE
(Rhodococcus
jostii) 		5 / 11 HIS A 249
HIS A 217
ASN A 157
HIS A 155
VAL A 202
 HPX  A 406 (-3.4A)
FE  A 400 ( 3.4A)
PEO  A 401 ( 4.1A)
FE  A 400 ( 3.5A)
None
 1.25A 5z0mA-3lm4A:
undetectable
5z0mB-3lm4A:
undetectable		 5z0mA-3lm4A:
12.06
5z0mB-3lm4A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_ACTA405_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 4x6g OXYR
(Pseudomonas
aeruginosa) 		4 / 6 THR A 129
PRO A 149
GLN A 203
ILE A 146
 PEO  A 401 (-3.7A)
None
None
None
 1.43A 6ef6A-4x6gA:
undetectable		 6ef6A-4x6gA:
22.76