SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'PEH'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 1m56 CYTOCHROME C OXIDASE
(Rhodobacter
sphaeroides) 		3 / 3 VAL C  63
TRP C  58
TRP C  59
 PEH  C2008 (-4.2A)
None
PEH  C2008 ( 3.9A)
 1.13A 2xdcC-1m56C:
undetectable
2xdcD-1m56C:
undetectable		 2xdcC-1m56C:
5.35
2xdcD-1m56C:
5.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1m56 CYTOCHROME C OXIDASE
(Rhodobacter
sphaeroides) 		3 / 3 VAL C  63
TRP C  58
TRP C  59
 PEH  C2008 (-4.2A)
None
PEH  C2008 ( 3.9A)
 1.16A 3zq8A-1m56C:
undetectable
3zq8B-1m56C:
undetectable		 3zq8A-1m56C:
5.35
3zq8B-1m56C:
5.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7A_A_MXDA1002_1
(ANDROGEN RECEPTOR)		 1m56 CYTOCHROME C OXIDASE
(Rhodobacter
sphaeroides) 		3 / 3 GLU C 241
TRP C 245
LYS C 236
 None
PEH  C2013 (-3.3A)
PEH  C2008 ( 4.3A)
 1.43A 4k7aA-1m56C:
0.9		 4k7aA-1m56C:
18.64