SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'PEE'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 3h1l CYTOCHROME B
(Gallus
gallus) 		6 / 12 ALA C 278
ILE C 281
MET C 125
LEU C 302
LEU C 329
LEU C 333
 3H1  C2001 ( 3.7A)
None
3H1  C2001 ( 4.7A)
HEM  C 502 ( 4.9A)
None
PEE  C2007 ( 4.0A)
 1.22A 1dtlA-3h1lC:
undetectable		 1dtlA-3h1lC:
15.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KB9_A_PCFA514_0
(CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3h1l MITOCHONDRIAL
UBIQUINOL-CYTOCHROME
-C REDUCTASE COMPLEX
CORE PROTEIN I
CYTOCHROME B
MITOCHONDRIAL
CYTOCHROME C1, HEME
PROTEIN
(Gallus
gallus;
Gallus
gallus;
Gallus
gallus) 		4 / 8 SER A 439
HIS C 222
PHE C 227
LYS D 226
 PEE  A2008 ( 4.1A)
PEE  A2008 (-4.1A)
None
None
 0.65A 1kb9A-3h1lA:
45.4
1kb9C-3h1lA:
undetectable
1kb9D-3h1lA:
undetectable
1kb9E-3h1lA:
undetectable		 1kb9A-3h1lA:
33.12
1kb9C-3h1lA:
21.04
1kb9D-3h1lA:
20.27
1kb9E-3h1lA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 3b74 UNCHARACTERIZED
PROTEIN YKL091C
(Saccharomyces
cerevisiae) 		5 / 12 TYR A 195
TYR A 137
ILE A 131
TYR A 109
LEU A 149
 PEE  A 311 (-4.0A)
PEE  A 311 (-3.8A)
PEE  A 311 ( 4.4A)
PEE  A 311 ( 4.8A)
None
 1.13A 1p91B-3b74A:
undetectable		 1p91B-3b74A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1xio ANABAENA SENSORY
RHODOPSIN
(Nostoc
sp.
PCC
7120) 		4 / 8 LEU A  84
TYR A 165
ARG A 151
THR A 170
 None
None
PEE  A 306 (-3.9A)
None
 0.85A 2einA-1xioA:
1.7
2einJ-1xioA:
undetectable		 2einA-1xioA:
21.56
2einJ-1xioA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_CHDA332_0
(CHOLOYLGLYCINE
HYDROLASE)		 3h1l CYTOCHROME B
(Gallus
gallus) 		5 / 12 ILE C  95
PHE C  96
ILE C 301
ILE C 305
LEU C 122
 None
PEE  C2007 (-3.9A)
None
None
3H1  C2001 ( 4.8A)
 1.18A 2rlcA-3h1lC:
undetectable		 2rlcA-3h1lC:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_C_ADNC601_1
(METHIONYL-TRNA
SYNTHETASE)		 2wqy SUCCINATE
DEHYDROGENASE
CYTOCHROME B, SMALL
SUBUNIT
(Gallus
gallus) 		5 / 11 ALA D  96
ALA D  98
GLY D  92
ASP D  36
ILE D  93
 None
PEE  D 109 ( 4.9A)
None
None
None
 1.14A 2x1lC-2wqyD:
undetectable		 2x1lC-2wqyD:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 2wqy SUCCINATE
DEHYDROGENASE
CYTOCHROME B, SMALL
SUBUNIT
(Gallus
gallus) 		4 / 5 ALA D  26
GLY D  32
CYH D  94
LYS D  95
 None
None
PEE  D 109 ( 4.8A)
None
 1.40A 2ylgA-2wqyD:
4.8		 2ylgA-2wqyD:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1xio ANABAENA SENSORY
RHODOPSIN
(Nostoc
sp.
PCC
7120) 		4 / 6 LEU A  84
TYR A 165
ARG A 151
THR A 170
 None
None
PEE  A 306 (-3.9A)
None
 0.77A 2zxwA-1xioA:
2.9
2zxwJ-1xioA:
undetectable		 2zxwA-1xioA:
21.56
2zxwJ-1xioA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4tl3 ANABAENA SENSORY
RHODOPSIN
(Nostoc
sp.
PCC
7120) 		4 / 6 LEU A  84
TYR A 165
ARG A 151
THR A 170
 None
None
None
PEE  A 304 ( 4.3A)
 0.80A 2zxwA-4tl3A:
2.8
2zxwJ-4tl3A:
undetectable		 2zxwA-4tl3A:
20.80
2zxwJ-4tl3A:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1xio ANABAENA SENSORY
RHODOPSIN
(Nostoc
sp.
PCC
7120) 		4 / 6 LEU A  84
TYR A 165
ARG A 151
THR A 170
 None
None
PEE  A 306 (-3.9A)
None
 0.86A 3abmA-1xioA:
2.8
3abmJ-1xioA:
undetectable		 3abmA-1xioA:
21.56
3abmJ-1xioA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4tl3 ANABAENA SENSORY
RHODOPSIN
(Nostoc
sp.
PCC
7120) 		4 / 6 LEU A  84
TYR A 165
ARG A 151
THR A 170
 None
None
None
PEE  A 304 ( 4.3A)
 0.89A 3abmA-4tl3A:
2.7
3abmJ-4tl3A:
undetectable		 3abmA-4tl3A:
20.80
3abmJ-4tl3A:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA301_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 5nmi CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN,
MITOCHONDRIAL
(Bos
taurus) 		4 / 6 ARG D 201
ILE C  78
TRP C  77
HIS D 200
 None
None
None
PEE  D 502 (-3.5A)
 1.14A 3deuA-5nmiD:
undetectable		 3deuA-5nmiD:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1xio ANABAENA SENSORY
RHODOPSIN
(Nostoc
sp.
PCC
7120) 		3 / 3 ARG A 155
ILE A 146
TRP A 147
 None
None
PEE  A 306 ( 3.6A)
 1.12A 3e7iB-1xioA:
undetectable		 3e7iB-1xioA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_B_LEIB16_0
(COIL SER L16D-PEN)		 5gyk MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 256
LYS A 249
LEU A 252
GLU A 255
 PEE  A 301 (-4.8A)
None
None
PEE  A 301 (-3.9A)
 1.10A 3h5gA-5gykA:
undetectable
3h5gB-5gykA:
undetectable		 3h5gA-5gykA:
10.00
3h5gB-5gykA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_2
(DIHYDROFOLATE
REDUCTASE)		 5xtc NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
11
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2
(Homo
sapiens) 		3 / 3 ARG V 129
ILE i 277
THR i 156
 None
PEE  V 202 (-4.6A)
None
 0.75A 3ia4D-5xtcV:
undetectable		 3ia4D-5xtcV:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_1
(NEURAMINIDASE)		 3b74 UNCHARACTERIZED
PROTEIN YKL091C
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 102
GLU A 126
TYR A 195
 None
PEE  A 311 ( 4.1A)
PEE  A 311 (-4.0A)
 0.95A 3k37B-3b74A:
undetectable		 3k37B-3b74A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1xio ANABAENA SENSORY
RHODOPSIN
(Nostoc
sp.
PCC
7120) 		3 / 3 ARG A 155
ILE A 146
TRP A 147
 None
None
PEE  A 306 ( 3.6A)
 1.06A 3nw2A-1xioA:
undetectable		 3nw2A-1xioA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA451_1
(CYTOCHROME P450
164A2)		 1xio ANABAENA SENSORY
RHODOPSIN
(Nostoc
sp.
PCC
7120) 		5 / 10 ALA A  91
LEU A  87
LEU A 105
ILE A 146
THR A 108
 None
None
None
None
PEE  A 309 ( 4.6A)
 1.32A 3r9cA-1xioA:
undetectable		 3r9cA-1xioA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA451_1
(CYTOCHROME P450
164A2)		 4tl3 ANABAENA SENSORY
RHODOPSIN
(Nostoc
sp.
PCC
7120) 		5 / 10 ALA A  91
LEU A  87
LEU A 105
ILE A 146
THR A 108
 None
None
None
None
PEE  A 319 ( 4.4A)
 1.32A 3r9cA-4tl3A:
undetectable		 3r9cA-4tl3A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_1
(PROTEASE)		 1xio ANABAENA SENSORY
RHODOPSIN
(Nostoc
sp.
PCC
7120) 		5 / 9 ILE A 141
GLY A 103
ILE A 102
ILE A 146
ILE A 142
 PEE  A 311 ( 4.5A)
None
None
None
None
 0.88A 3s45A-1xioA:
undetectable		 3s45A-1xioA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_D_ACTD4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3h1l CYTOCHROME B
(Gallus
gallus) 		4 / 5 LEU C 302
LEU C 103
GLY C 100
GLY C 102
 HEM  C 502 ( 4.9A)
None
PEE  C2007 ( 4.1A)
None
 0.80A 3si7C-3h1lC:
undetectable
3si7D-3h1lC:
undetectable		 3si7C-3h1lC:
22.76
3si7D-3h1lC:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA502_0
(OXIDOREDUCTASE,
FMN-BINDING)		 3h1l CYTOCHROME B
MITOCHONDRIAL
UBIQUINOL-CYTOCHROME
C REDUCTASE 14 KDA
PROTEIN
(Gallus
gallus;
Gallus
gallus) 		4 / 7 THR C 317
ASN C  27
LEU F  66
PHE C 318
 PEE  C2007 (-3.3A)
None
None
None
 1.34A 4awuA-3h1lC:
undetectable		 4awuA-3h1lC:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_A_SVRA301_1
(NUCLEOCAPSID PROTEIN)		 3b74 UNCHARACTERIZED
PROTEIN YKL091C
(Saccharomyces
cerevisiae) 		5 / 11 ALA A 200
VAL A 230
MET A 226
PHE A 223
ILE A 216
 PEE  A 311 ( 4.3A)
None
PEE  A 311 ( 4.6A)
None
None
 1.21A 4j4vA-3b74A:
0.7		 4j4vA-3b74A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_D_SVRD301_1
(NUCLEOCAPSID PROTEIN)		 3b74 UNCHARACTERIZED
PROTEIN YKL091C
(Saccharomyces
cerevisiae) 		5 / 11 ALA A 200
VAL A 230
MET A 226
PHE A 223
ILE A 244
 PEE  A 311 ( 4.3A)
None
PEE  A 311 ( 4.6A)
None
None
 1.47A 4j4vD-3b74A:
0.0
4j4vE-3b74A:
undetectable		 4j4vD-3b74A:
19.70
4j4vE-3b74A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3b74 UNCHARACTERIZED
PROTEIN YKL091C
(Saccharomyces
cerevisiae) 		4 / 8 VAL A 199
TYR A 195
LEU A 128
LEU A 179
 None
PEE  A 311 (-4.0A)
PEE  A 311 (-4.6A)
None
 1.04A 4jtrA-3b74A:
undetectable		 4jtrA-3b74A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 2wqy SUCCINATE
DEHYDROGENASE
CYTOCHROME B, SMALL
SUBUNIT
(Gallus
gallus) 		4 / 5 ALA D  26
GLY D  32
CYH D  94
LYS D  95
 None
None
PEE  D 109 ( 4.8A)
None
 1.48A 5jt4A-2wqyD:
4.7		 5jt4A-2wqyD:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_0
(REGULATORY PROTEIN
TETR)		 5xtc NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT 1
NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
13
(Homo
sapiens;
Homo
sapiens) 		5 / 12 SER S  46
GLU S  49
LEU S  47
TYR W 143
PHE W 140
 None
None
None
None
PEE  W 201 (-3.5A)
 1.29A 5vlmF-5xtcS:
undetectable		 5vlmF-5xtcS:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xio ANABAENA SENSORY
RHODOPSIN
(Nostoc
sp.
PCC
7120) 		4 / 6 LEU A  84
TYR A 165
ARG A 151
THR A 170
 None
None
PEE  A 306 (-3.9A)
None
 0.83A 5x1fA-1xioA:
2.3
5x1fJ-1xioA:
undetectable		 5x1fA-1xioA:
21.56
5x1fJ-1xioA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4tl3 ANABAENA SENSORY
RHODOPSIN
(Nostoc
sp.
PCC
7120) 		4 / 6 LEU A  84
TYR A 165
ARG A 151
THR A 170
 None
None
None
PEE  A 304 ( 4.3A)
 0.88A 5x1fA-4tl3A:
2.3
5x1fJ-4tl3A:
undetectable		 5x1fA-4tl3A:
20.80
5x1fJ-4tl3A:
12.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HU9_C_PCFC607_0
(CYTOCHROME B)		 3h1l CYTOCHROME B
(Gallus
gallus) 		7 / 10 TRP C  31
PHE C  96
TYR C 104
TYR C 105
THR C 315
PHE C 326
VAL C 330
 PEE  C2007 ( 3.1A)
PEE  C2007 (-3.9A)
PEE  C2007 (-3.5A)
PEE  C2007 ( 4.3A)
None
PEE  C2007 ( 4.8A)
PEE  C2007 ( 4.7A)
 1.37A 6hu9C-3h1lC:
5.3		 6hu9C-3h1lC:
52.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HU9_C_PCFC607_0
(CYTOCHROME B)		 3h1l CYTOCHROME B
(Gallus
gallus) 		7 / 10 TRP C  31
PHE C  96
TYR C 104
TYR C 105
THR C 317
PHE C 326
VAL C 330
 PEE  C2007 ( 3.1A)
PEE  C2007 (-3.9A)
PEE  C2007 (-3.5A)
PEE  C2007 ( 4.3A)
PEE  C2007 (-3.3A)
PEE  C2007 ( 4.8A)
PEE  C2007 ( 4.7A)
 0.39A 6hu9C-3h1lC:
5.3		 6hu9C-3h1lC:
52.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HU9_C_PCFC607_0
(CYTOCHROME B)		 5nmi CYTOCHROME B
(Bos
taurus) 		5 / 10 TRP C  30
TYR C 103
TYR C 104
PHE C 325
VAL C 329
 PEE  C 504 ( 3.6A)
PEE  C 504 (-3.2A)
PEE  C 504 (-4.4A)
PEE  C 504 (-4.6A)
PEE  C 504 ( 4.1A)
 0.27A 6hu9C-5nmiC:
4.8		 6hu9C-5nmiC:
50.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HU9_N_PCFN606_0
(CYTOCHROME B)		 3h1l CYTOCHROME B
(Gallus
gallus) 		7 / 12 TRP C  31
PHE C  96
TYR C 104
TYR C 105
THR C 315
VAL C 330
TYR C 359
 PEE  C2007 ( 3.1A)
PEE  C2007 (-3.9A)
PEE  C2007 (-3.5A)
PEE  C2007 ( 4.3A)
None
PEE  C2007 ( 4.7A)
None
 1.42A 6hu9N-3h1lC:
undetectable		 6hu9N-3h1lC:
52.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HU9_N_PCFN606_0
(CYTOCHROME B)		 3h1l CYTOCHROME B
(Gallus
gallus) 		7 / 12 TRP C  31
PHE C  96
TYR C 104
TYR C 105
THR C 317
VAL C 330
TYR C 359
 PEE  C2007 ( 3.1A)
PEE  C2007 (-3.9A)
PEE  C2007 (-3.5A)
PEE  C2007 ( 4.3A)
PEE  C2007 (-3.3A)
PEE  C2007 ( 4.7A)
None
 0.43A 6hu9N-3h1lC:
undetectable		 6hu9N-3h1lC:
52.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HU9_N_PCFN606_0
(CYTOCHROME B)		 5nmi CYTOCHROME B
(Bos
taurus) 		5 / 12 TRP C  30
MET C  96
TYR C 103
TYR C 104
TYR C 358
 PEE  C 504 ( 3.6A)
PEE  C 504 (-4.5A)
PEE  C 504 (-3.2A)
PEE  C 504 (-4.4A)
None
 0.58A 6hu9N-5nmiC:
undetectable		 6hu9N-5nmiC:
50.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HU9_N_PCFN606_0
(CYTOCHROME B)		 5nmi CYTOCHROME B
(Bos
taurus) 		5 / 12 TRP C  30
TYR C 103
TYR C 104
VAL C 329
TYR C 358
 PEE  C 504 ( 3.6A)
PEE  C 504 (-3.2A)
PEE  C 504 (-4.4A)
PEE  C 504 ( 4.1A)
None
 0.31A 6hu9N-5nmiC:
undetectable		 6hu9N-5nmiC:
50.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J21_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 3b74 UNCHARACTERIZED
PROTEIN YKL091C
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 196
VAL A 199
ILE A 184
VAL A 230
PHE A 214
 PEE  A 311 (-4.8A)
None
PEE  A 311 ( 3.9A)
None
PEE  A 311 ( 4.4A)
 1.42A 6j21A-3b74A:
undetectable		 6j21A-3b74A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xio ANABAENA SENSORY
RHODOPSIN
(Nostoc
sp.
PCC
7120) 		4 / 6 LEU A  84
TYR A 165
ARG A 151
THR A 170
 None
None
PEE  A 306 (-3.9A)
None
 1.14A 6nmfN-1xioA:
1.6
6nmfW-1xioA:
undetectable		 6nmfN-1xioA:
21.56
6nmfW-1xioA:
12.67