SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'PEB'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4002_1
(SERUM ALBUMIN)		 3v57 PHYCOERYTHRIN BETA
SUBUNIT
(Porphyridium
purpureum) 		4 / 4 ARG B  37
ALA B  40
ALA B 162
GLU B 164
 None
PEB  B 204 ( 4.0A)
None
None
 1.18A 1e7bA-3v57B:
undetectable		 1e7bA-3v57B:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_A_EAAA223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5nb3 PHYCOERYTHRIN BETA
SUBUNIT,PHYCOERYTHRI
N BETA SUBUNIT
(Phormidium
rubidum) 		4 / 8 PHE M  28
GLY M  32
LEU M  36
PHE M   5
 None
MPD  M 204 ( 4.0A)
PEB  M 187 (-4.2A)
None
 0.82A 1gsfA-5nb3M:
undetectable		 1gsfA-5nb3M:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_B_EAAB223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5nb3 PHYCOERYTHRIN BETA
SUBUNIT,PHYCOERYTHRI
N BETA SUBUNIT
(Phormidium
rubidum) 		4 / 8 PHE M  28
GLY M  32
LEU M  36
PHE M   5
 None
MPD  M 204 ( 4.0A)
PEB  M 187 (-4.2A)
None
 0.83A 1gsfB-5nb3M:
undetectable		 1gsfB-5nb3M:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_D_EAAD223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5nb3 PHYCOERYTHRIN BETA
SUBUNIT,PHYCOERYTHRI
N BETA SUBUNIT
(Phormidium
rubidum) 		4 / 8 PHE M  28
GLY M  32
LEU M  36
PHE M   5
 None
MPD  M 204 ( 4.0A)
PEB  M 187 (-4.2A)
None
 0.83A 1gsfD-5nb3M:
undetectable		 1gsfD-5nb3M:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWH_A_PEMA501_1
(HEMOGLOBIN ALPHA
CHAIN)		 3v57 PHYCOERYTHRIN ALPHA
SUBUNIT
(Porphyridium
purpureum) 		4 / 6 ALA A  50
LYS A  53
ASP A  57
ALA A  58
 PEB  A 202 (-3.5A)
None
None
None
 0.29A 1iwhA-3v57A:
9.1		 1iwhA-3v57A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_2
(DIHYDROFOLATE
REDUCTASE)		 1xg0 B-PHYCOERYTHRIN BETA
CHAIN
(Rhodomonas
sp.
CS24) 		4 / 4 SER C  32
ILE C  31
VAL C  41
THR C 153
 None
None
None
PEB  C 258 (-4.3A)
 1.21A 1u70A-1xg0C:
undetectable		 1u70A-1xg0C:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1xg0 B-PHYCOERYTHRIN BETA
CHAIN
(Rhodomonas
sp.
CS24) 		3 / 3 SER C  46
ASP C  39
CYH C 158
 None
PEB  C 258 (-3.1A)
PEB  C 258 (-1.8A)
 0.99A 2br4E-1xg0C:
undetectable		 2br4E-1xg0C:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2vjh PHYCOERYTHRIN BETA
SUBUNIT
(Gloeobacter
violaceus) 		3 / 3 SER B  46
ASP B  39
CYH B 158
 None
PEB  B1158 (-3.3A)
PEB  B1158 (-1.6A)
 1.07A 2br4E-2vjhB:
undetectable		 2br4E-2vjhB:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3v57 PHYCOERYTHRIN BETA
SUBUNIT
(Porphyridium
purpureum) 		3 / 3 SER B  46
ASP B  39
CYH B 158
 None
PEB  B 204 (-3.3A)
PEB  B 204 ( 1.7A)
 1.15A 2br4E-3v57B:
undetectable		 2br4E-3v57B:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4lmx CRYPTOPHYTE
PHYCOERYTHRIN (BETA
CHAIN)
(Hemiselmis
andersenii) 		3 / 3 SER B  46
ASP B  39
CYH B 158
 None
PEB  B 202 (-3.3A)
PEB  B 202 (-1.8A)
 0.86A 2br4E-4lmxB:
undetectable		 2br4E-4lmxB:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_C_SPMC1434_1
(NITROALKANE OXIDASE)		 1xg0 B-PHYCOERYTHRIN BETA
CHAIN
(Rhodomonas
sp.
CS24) 		5 / 12 VAL C 165
ALA C 162
LEU C 161
SER C  40
VAL C  41
 None
None
None
PEB  C 258 (-3.1A)
None
 1.23A 2c12C-1xg0C:
undetectable		 2c12C-1xg0C:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_A_J01A1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3v57 PHYCOERYTHRIN BETA
SUBUNIT
(Porphyridium
purpureum) 		5 / 12 SER B  43
ILE B  44
ALA B  40
VAL B 165
ALA B 162
 None
None
PEB  B 204 ( 4.0A)
None
None
 1.25A 2japA-3v57B:
undetectable		 2japA-3v57B:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_B_J01B1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3v57 PHYCOERYTHRIN BETA
SUBUNIT
(Porphyridium
purpureum) 		5 / 12 SER B  43
ILE B  44
ALA B  40
VAL B 165
ALA B 162
 None
None
PEB  B 204 ( 4.0A)
None
None
 1.24A 2japB-3v57B:
undetectable		 2japB-3v57B:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_C_J01C1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3v57 PHYCOERYTHRIN BETA
SUBUNIT
(Porphyridium
purpureum) 		5 / 12 SER B  43
ILE B  44
ALA B  40
VAL B 165
ALA B 162
 None
None
PEB  B 204 ( 4.0A)
None
None
 1.23A 2japC-3v57B:
undetectable		 2japC-3v57B:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_D_J01D1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3v57 PHYCOERYTHRIN BETA
SUBUNIT
(Porphyridium
purpureum) 		5 / 12 SER B  43
ILE B  44
ALA B  40
VAL B 165
ALA B 162
 None
None
PEB  B 204 ( 4.0A)
None
None
 1.24A 2japD-3v57B:
undetectable		 2japD-3v57B:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 2vjh PHYCOERYTHRIN BETA
SUBUNIT
(Gloeobacter
violaceus) 		3 / 3 LEU B 113
TYR B 117
GLY B 121
 PEB  B1082 (-4.5A)
None
MEN  B  72 ( 4.5A)
 0.60A 2ocuA-2vjhB:
undetectable		 2ocuA-2vjhB:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_F_CSCF1383_2
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 4lmx CRYPTOPHYTE
PHYCOERYTHRIN (BETA
CHAIN)
(Hemiselmis
andersenii) 		3 / 3 LEU B  98
MET B  38
MET B 134
 None
PEB  B 202 (-4.7A)
None
 1.06A 2vavF-4lmxB:
undetectable		 2vavF-4lmxB:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_F_ASDF1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1f99 R-PHYCOCYANIN
(Polysiphonia
urceolata) 		4 / 8 LEU A  24
ALA A   8
LEU A   5
ALA B  99
 PEB  B 355 ( 4.5A)
None
None
None
 0.90A 2vcvF-1f99A:
undetectable		 2vcvF-1f99A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)		 3v57 PHYCOERYTHRIN ALPHA
SUBUNIT
(Porphyridium
purpureum) 		4 / 7 LEU A 120
ASN A 121
GLU A  71
LEU A  66
 PEB  A 201 (-4.6A)
None
None
PEB  A 201 ( 3.8A)
 1.17A 2w8yA-3v57A:
undetectable		 2w8yA-3v57A:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_A_FOLA164_0
(DIHYDROFOLATE
REDUCTASE)		 2bv8 C-PHYCOCYANIN ALPHA
SUBUNIT
C-PHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis;
Gracilaria
chilensis) 		5 / 12 ILE A   9
ALA A  12
GLU A  23
LEU A  24
ILE B  44
 None
None
None
PEB  B1175 ( 4.6A)
None
 1.32A 2zzaA-2bv8A:
undetectable		 2zzaA-2bv8A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_B_FOLB164_0
(DIHYDROFOLATE
REDUCTASE)		 2bv8 C-PHYCOCYANIN ALPHA
SUBUNIT
C-PHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis;
Gracilaria
chilensis) 		5 / 11 ILE A   9
ALA A  12
GLU A  23
LEU A  24
ILE B  44
 None
None
None
PEB  B1175 ( 4.6A)
None
 1.34A 2zzaB-2bv8A:
undetectable		 2zzaB-2bv8A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_B_MTXB164_1
(DIHYDROFOLATE
REDUCTASE)		 2bv8 C-PHYCOCYANIN ALPHA
SUBUNIT
C-PHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis) 		5 / 12 ILE A   9
ALA A  12
GLU A  23
LEU A  24
ILE B  44
 None
None
None
PEB  B1175 ( 4.6A)
None
 1.30A 3ia4B-2bv8A:
undetectable		 3ia4B-2bv8A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_A_CAMA423_0
(CYTOCHROME P450)		 3v57 PHYCOERYTHRIN ALPHA
SUBUNIT
(Porphyridium
purpureum) 		5 / 10 THR A 134
LEU A 159
LEU A 156
VAL A  52
VAL A  51
 None
None
None
None
PEB  A 202 (-4.7A)
 1.26A 3lxiA-3v57A:
undetectable		 3lxiA-3v57A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_B_CAMB423_0
(CYTOCHROME P450)		 3v57 PHYCOERYTHRIN ALPHA
SUBUNIT
(Porphyridium
purpureum) 		5 / 11 THR A 134
LEU A 159
LEU A 156
VAL A  52
VAL A  51
 None
None
None
None
PEB  A 202 (-4.7A)
 1.31A 3lxiB-3v57A:
undetectable		 3lxiB-3v57A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_D_08JD4_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2bv8 C-PHYCOCYANIN ALPHA
SUBUNIT
C-PHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis) 		4 / 8 VAL B  41
LEU A  24
LEU B  38
ILE A   5
 None
PEB  B1175 ( 4.6A)
PEB  B1175 ( 4.0A)
None
 0.90A 3u5kD-2bv8B:
undetectable		 3u5kD-2bv8B:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 3v57 PHYCOERYTHRIN ALPHA
SUBUNIT
(Porphyridium
purpureum) 		5 / 9 THR A 134
LEU A 159
LEU A 156
VAL A  52
VAL A  51
 None
None
None
None
PEB  A 202 (-4.7A)
 1.26A 4c9pA-3v57A:
undetectable		 4c9pA-3v57A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 3v57 PHYCOERYTHRIN ALPHA
SUBUNIT
(Porphyridium
purpureum) 		5 / 10 THR A 134
LEU A 159
LEU A 156
VAL A  52
VAL A  51
 None
None
None
None
PEB  A 202 (-4.7A)
 1.25A 4c9pB-3v57A:
undetectable		 4c9pB-3v57A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)		 1f99 R-PHYCOCYANIN
(Polysiphonia
urceolata) 		4 / 7 ASN B  35
LEU B  38
ARG B  37
TYR A  31
 PEB  B 355 (-3.5A)
PEB  B 355 ( 4.2A)
None
None
 0.90A 4cp3A-1f99B:
0.0
4cp3B-1f99B:
0.9		 4cp3A-1f99B:
20.81
4cp3B-1f99B:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)		 2bv8 C-PHYCOCYANIN ALPHA
SUBUNIT
C-PHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis) 		4 / 7 ASN B  35
LEU B  38
ARG B  37
TYR A  31
 PEB  B1175 (-3.6A)
PEB  B1175 ( 4.0A)
None
None
 1.02A 4cp3A-2bv8B:
undetectable
4cp3B-2bv8B:
undetectable		 4cp3A-2bv8B:
20.57
4cp3B-2bv8B:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2vjh PHYCOERYTHRIN ALPHA
CHAIN
PHYCOERYTHRIN BETA
SUBUNIT
(Gloeobacter
violaceus) 		5 / 12 LEU B  38
ASN A  30
ALA B  99
ALA A  12
VAL A   8
 PEB  B1158 (-4.2A)
None
None
None
None
 1.09A 4nkxC-2vjhB:
undetectable		 4nkxC-2vjhB:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_2
(TUBULIN BETA CHAIN)		 1xg0 B-PHYCOERYTHRIN BETA
CHAIN
(Rhodomonas
sp.
CS24) 		5 / 12 CYH C  73
LEU C  66
ASN C 125
ALA C 130
VAL C  56
 PEB  C 282 (-3.5A)
PEB  C 282 ( 4.8A)
None
PEB  C 282 ( 3.9A)
None
 1.23A 4x1iB-1xg0C:
undetectable		 4x1iB-1xg0C:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_A_SAMA1304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 1xg0 B-PHYCOERYTHRIN BETA
CHAIN
(Rhodomonas
sp.
CS24) 		5 / 12 GLY C 121
ASN C  63
CYH C  73
CYH C  82
LEU C  66
 MEN  C  72 ( 4.5A)
None
PEB  C 282 (-3.5A)
PEB  C 282 (-1.8A)
PEB  C 282 ( 4.8A)
 1.36A 5lsuA-1xg0C:
undetectable		 5lsuA-1xg0C:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_A_SAMA1304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 2vjh PHYCOERYTHRIN BETA
SUBUNIT
(Gloeobacter
violaceus) 		5 / 12 ASN B  63
CYH B  73
ARG B  78
CYH B  82
LEU B  66
 None
PEB  B1082 (-3.5A)
PEB  B1082 (-4.5A)
PEB  B1082 (-1.6A)
PEB  B1082 ( 4.7A)
 1.35A 5lsuA-2vjhB:
undetectable		 5lsuA-2vjhB:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_A_SAMA1304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 2vjh PHYCOERYTHRIN BETA
SUBUNIT
(Gloeobacter
violaceus) 		5 / 12 GLY B 121
ASN B  63
CYH B  73
CYH B  82
LEU B  66
 MEN  B  72 ( 4.5A)
None
PEB  B1082 (-3.5A)
PEB  B1082 (-1.6A)
PEB  B1082 ( 4.7A)
 1.36A 5lsuA-2vjhB:
undetectable		 5lsuA-2vjhB:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_A_SAMA1304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 3v57 PHYCOERYTHRIN BETA
SUBUNIT
(Porphyridium
purpureum) 		5 / 12 GLY B 121
ASN B  63
CYH B  73
CYH B  82
LEU B  66
 MEN  B  72 ( 4.5A)
None
PEB  B 203 (-3.4A)
PEB  B 203 (-1.8A)
PEB  B 203 ( 4.6A)
 1.41A 5lsuA-3v57B:
undetectable		 5lsuA-3v57B:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_A_SAMA1304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 5nb3 PHYCOERYTHRIN BETA
SUBUNIT,PHYCOERYTHRI
N BETA SUBUNIT
(Phormidium
rubidum) 		5 / 12 GLY M 119
ASN M  61
CYH M  71
CYH M  80
LEU M  64
 MEN  M  70 ( 4.6A)
None
PEB  M 186 (-3.5A)
PEB  M 186 (-2.0A)
PEB  M 186 ( 4.5A)
 1.34A 5lsuA-5nb3M:
undetectable		 5lsuA-5nb3M:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA502_1
(CYTOCHROME P450 2C9)		 3v57 PHYCOERYTHRIN ALPHA
SUBUNIT
PHYCOERYTHRIN BETA
SUBUNIT
(Porphyridium
purpureum) 		5 / 12 ALA B  40
LEU B 161
VAL B 165
VAL B  93
THR A   6
 PEB  B 204 ( 4.0A)
None
None
None
None
 1.23A 5x24A-3v57B:
undetectable		 5x24A-3v57B:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 5nb3 PHYCOERYTHRIN ALPHA
SUBUNIT,PHYCOERYTHRI
N ALPHA
SUBUNIT,PHYCOERYTHRI
N ALPHA SUBUNIT
PHYCOERYTHRIN BETA
SUBUNIT,PHYCOERYTHRI
N BETA SUBUNIT
(Phormidium
rubidum;
Phormidium
rubidum) 		5 / 12 ALA A 159
LEU A 155
SER M   6
VAL A   4
TYR A  89
 None
None
None
None
PEB  A 166 (-4.3A)
 1.07A 6djzC-5nb3A:
undetectable		 6djzC-5nb3A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5nb3 PHYCOERYTHRIN ALPHA
SUBUNIT,PHYCOERYTHRI
N ALPHA
SUBUNIT,PHYCOERYTHRI
N ALPHA SUBUNIT
(Phormidium
rubidum) 		4 / 5 ALA A  40
TYR A 152
GLN A  94
ILE A  93
 None
PEB  A 167 ( 4.4A)
None
None
 1.26A 6f6sA-5nb3A:
undetectable
6f6sB-5nb3A:
undetectable		 6f6sA-5nb3A:
23.53
6f6sB-5nb3A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IE8_A_CHDA201_0
(REGULATORY PROTEIN)		 1xg0 PHYCOERYTHRIN
ALPHA-3 CHAIN
B-PHYCOERYTHRIN BETA
CHAIN
(Rhodomonas
sp.
CS24;
Rhodomonas
sp.
CS24) 		5 / 12 ILE C  31
ALA A  31
LEU C  38
ARG A  17
ASP A  35
 None
None
PEB  C 258 (-4.2A)
PEB  C 258 (-3.0A)
None
 1.19A 6ie8A-1xg0C:
undetectable		 6ie8A-1xg0C:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 5nb3 PHYCOERYTHRIN ALPHA
SUBUNIT,PHYCOERYTHRI
N ALPHA
SUBUNIT,PHYCOERYTHRI
N ALPHA SUBUNIT
(Phormidium
rubidum) 		4 / 5 GLY A 109
LEU A 105
SER A 162
GLN A 113
 PEB  A 166 ( 4.7A)
None
None
None
 0.90A 6ji6A-5nb3A:
undetectable		 6ji6A-5nb3A:
18.10